By Scientia Professor Perminder Singh Sachdev

Journal articles

Seeher ; Low LF; Reppermund S; Slavin M; Draper BM; Kang K; Kochan N; Trollor JN; Sachdev PS; Brodaty H, 2014, 'Correlates of psychological distress in study partners of older people with and without mild cognitive impairment (MCI) – the Sydney Memory and Ageing Study', Aging and Mental Health, 18, pp. 694 - 705, http://dx.doi.org/10.1080/13607863.2013.875123

Lee T; Sachdev P, 2014, 'The contributions of twin studies to the understanding of brain ageing and neurocognitive disorders', Current Opinion in Psychiatry, 27, pp. 122 - 127, http://dx.doi.org/10.1097/YCO.0000000000000039

Jiang J; Sachdev P; Lipnicki DM; Zhang H; Liu T; Suo C; Zhuang L; Crawford J; Reppermund S; Trollor J; Brodaty H; Wen W; Zhu W, 2014, 'A longitudinal study of brain atrophy over two years in community-dwelling older individuals', NeuroImage, 86, pp. 203 - 211, http://dx.doi.org/10.1016/j.neuroimage.2013.08.022

Song F; Poljak A; Kochan N; Raftery M; Brodaty H; Smythe GA; Sachdev PS, 2014, 'Plasma protein profiling of Mild Cognitive Impairment and Alzheimer’s disease using iTRAQ quantitative proteomics', Proteome Science, 12, pp. 5, http://dx.doi.org/10.1186/1477-5956-12-5

Lo AHY; Woodman RJ; Pachana NA; Byrne GJ; Sachdev PS, 2014, 'Associations between lifestyle and cognitive function over time in women aged 40-79 years', Journal of Alzheimer's Disease, 39, pp. 371 - 383, http://dx.doi.org/10.3233/jad-130971

Braidy N; Brew BJ; Inestrosa NC; Chung R; Sachdev P; Guillemin GJ, 2014, 'Changes in Cathepsin D and Beclin-1 mRNA and protein expression by the excitotoxin quinolinic acid in human astrocytes and neurons', Metabolic Brain Disease, 29, pp. 873 - 883, http://dx.doi.org/10.1007/s11011-014-9557-9

Sachdev P; Kalaria R; O'Brien J; Skoog I; Alladi S; Black SE; Blacker D; Blazer DG; Chen C; Chui H; Ganguli M; Jellinger K; Jeste DV; Pasquier F; Paulsen J; Prins N; Rockwood K; Roman G; Scheltens P, 2014, 'Diagnostic criteria for vascular cognitive disorders: A VASCOG statement', Alzheimer Disease and Associated Disorders, 28, pp. 206 - 218, http://dx.doi.org/10.1097/wad.0000000000000034

Cherbuin N; Kumar R; Sachdev PS; Anstey KJ, 2014, 'Dietary mineral intake and risk of mild cognitive impairment: The PATH through life project', Frontiers in Aging Neuroscience, 6, pp. 4, http://dx.doi.org/10.3389/fnagi.2014.00004

Ising M; Mather KA; Zimmermann P; Brückl T; Höhne N; Heck A; Schenk LA; Rujescu D; Armstrong NJ; Sachdev PS; Reppermund S, 2014, 'Genetic effects on information processing speed are moderated by age - Converging results from three samples', Genes, Brain and Behavior, 13, pp. 501 - 507, http://dx.doi.org/10.1111/gbb.12132

Wong AKW; Lord SR; Trollor JN; Sturnieks DL; Delbaere K; Menant J; Brodaty H; Sachdev PS; Close JCT, 2014, 'High arterial pulse wave velocity is a risk factor for falls in community-dwelling older people', Journal of the American Geriatrics Society, 62, pp. 1534 - 1539, http://dx.doi.org/10.1111/jgs.12931

Dong Y; Slavin MJ; Chan BPL; Venketasubramanian N; Sharma VK; Collinson SL; Sachdev PS; Chen CLH, 2014, 'Improving screening for vascular cognitive impairment at three to six months after mild ischemic stroke and transient ischemic attack', International Psychogeriatrics, 26, pp. 787 - 793, http://dx.doi.org/10.1017/S1041610213002457

Brodaty H; Mothakunnel A; de Vel-Palumbo M; Ames D; Ellis KA; Reppermund S; Kochan NA; Savage G; Trollor JN; Crawford J; Sachdev PS, 2014, 'Influence of population versus convenience sampling on sample characteristics in studies of cognitive aging', Annals of Epidemiology, 24, pp. 63 - 71, http://dx.doi.org/10.1016/j.annepidem.2013.10.005

Gates NJ; Sachdev P, 2014, 'Is cognitive training an effective treatment for preclinical and early alzheimer's disease?', Journal of Alzheimer's Disease, 42, pp. S551 - S559, http://dx.doi.org/10.3233/jad-141302

Braidy N; Poljak A; Marjo C; Rutlidge H; Rich A; Jayasena T; Inestrosa NC; Sachdev P, 2014, 'Metal and complementary molecular bioimaging in alzheimer's disease', Frontiers in Aging Neuroscience, 6, pp. 138, http://dx.doi.org/10.3389/fnagi.2014.00138

Raamana PR; Wen W; Kochan NA; Brodaty H; Sachdev PS; Wang L; Beg MF, 2014, 'Novel ThickNet features for the discrimination of amnestic MCI subtypes', NeuroImage: Clinical, 6, pp. 284 - 295, http://dx.doi.org/10.1016/j.nicl.2014.09.005

Mortby ME; Burns R; Janke AL; Sachdev PS; Anstey KJ; Cherbuin N, 2014, 'Relating education, brain structure, and cognition: The role of cardiovascular disease risk factors', BioMed Research International, 2014, pp. 271487, http://dx.doi.org/10.1155/2014/271487

Assareh AA; Mather KA; Crawford JD; Wen W; Anstey KJ; Easteal S; Tan X; Mack HA; Kwok JBJ; Schofield PR; Sachdev PS; Schofield P, 2014, 'Renin-angiotensin system genetic polymorphisms and brain white matter lesions in older australians', American Journal of Hypertension, 27, pp. 1191 - 1198, http://dx.doi.org/10.1093/ajh/hpu035

Shiner E; Taylor L; Mohan A; Watson S; Sachdev PSI, 2014, 'Severe depression masquerading as Creutzfeldt-Jakob disease', BMJ case reports, 2014, http://dx.doi.org/10.1136/bcr-2013-203352

Mohan A; Lee T; Sachdev P, 2014, 'Surviving acute cyanide poisoning: a longitudinal neuropsychological investigation with interval MRI', BMJ case reports, 2014, http://dx.doi.org/10.1136/bcr-2013-203025

Thompson PM; Stein JL; Medland SE; Hibar DP; Vasquez AA; Renteria ME; Toro R; Jahanshad N; Schumann G; Franke B; Wright MJ; Martin NG; Agartz I; Alda M; Alhusaini S; Almasy L; Almeida J; Alpert K; Andreasen NC; Andreassen OA; Apostolova LG; Appel K; Armstrong NJ; Aribisala B; Bastin ME; Bauer M; Bearden CE; Bergmann Ø; Binder EB; Blangero J; Bockholt HJ; Bøen E; Bois C; Boomsma DI; Booth T; Bowman IJ; Bralten J; Brouwer RM; Brunner HG; Brohawn DG; Buckner RL; Buitelaar J; Bulayeva K; Bustillo JR; Calhoun VD; Cannon DM; Cantor RM; Carless MA; Caseras X; Cavalleri GL; Chakravarty MM; Chang KD; Ching CRK; Christoforou A; Cichon S; Clark VP; Conrod P; Coppola G; Crespo-Facorro B; Curran JE; Czisch M; Deary IJ; de Geus EJC; den Braber A; Delvecchio G; Depondt C; de Haan L; de Zubicaray GI; Dima D; Dimitrova R; Djurovic S; Dong H; Donohoe G; Duggirala R; Dyer TD; Ehrlich S; Ekman CJ; Elvsåshagen T; Emsell L; Erk S; Espeseth T; Fagerness J; Fears S; Fedko I; Fernández G; Fisher SE; Foroud T; Fox PT; Francks C; Frangou S; Frey EM; Frodl T; Frouin V; Garavan H; Giddaluru S; Glahn DC; Godlewska B; Goldstein RZ; Gollub RL; Grabe HJ, 2014, 'The ENIGMA Consortium: Large-scale collaborative analyses of neuroimaging and genetic data', Brain Imaging and Behavior, 8, pp. 153 - 182, http://dx.doi.org/10.1007/s11682-013-9269-5

Batouli SAH; Trollor JN; Wen W; Sachdev PS, 2014, 'The heritability of volumes of brain structures and its relationship to age: A review of twin and family studies', Ageing Research Reviews, 13, pp. 1 - 9, http://dx.doi.org/10.1016/j.arr.2013.10.003

Raamana PR; Wen W; Kochan NA; Brodaty H; Sachdev PS; Wang L; Beg MF, 2014, 'The sub-classification of amnestic mild cognitive impairment using MRI-based cortical thickness measures', Frontiers in Neurology, 5 MAY, pp. 76, http://dx.doi.org/10.3389/fneur.2014.00076

Braidy N; Gai W-P; Xu YH; Sachdev P; Guillemin GJ; Jiang X-M; Ballard JWO; Horan MP; Fang ZM; Chong BH; Chan DKY, 2014, 'Alpha-Synuclein Transmission and Mitochondrial Toxicity in Primary Human Foetal Enteric Neurons In Vitro', Neurotoxicity Research, 25, pp. 170 - 182, http://dx.doi.org/10.1007/s12640-013-9420-5

Assareh AA; Piguet O; Lye TC; Mather KA; Broe GA; Schofield PR; Sachdev PS; Kwok JB; Schofield P, 2014, 'Association of SORL1 gene variants with hippocampal and cerebral atrophy and Alzheimer's disease', Current Alzheimer Research, 11, pp. 558 - 563, http://dx.doi.org/10.2174/1567205011666140618101408

Coupland KG; Mellick GD; Silburn PA; Mather K; Armstrong NJ; Sachdev PS; Brodaty H; Huang Y; Halliday GM; Hallupp M; Kim WS; Dobson-Stone C; Kwok JBJ; Kim W; Schofield P, 2014, 'DNA methylation of the MAPT gene in Parkinson's disease cohorts and modulation by vitamin E In Vitro', Movement Disorders, 29, pp. 1606 - 1614, http://dx.doi.org/10.1002/mds.25784

Batouli SAH; Sachdev PS; Wen W; Trollor JN; Wright MJ; Ames D, 2014, 'Heritability of brain volumes in older adults: The Older Australian Twins Study', Neurobiology of Aging, 35, pp. 937e5 - 937e18, http://dx.doi.org/10.1016/j.neurobiolaging.2013.10.079

Fuchs T; Trollor JN; Crawford J; Baune BT; Samaras K; Campbell L; Breit SN; Brodaty H; Sachdev P; Smith E; Brown DA, 2014, 'Macrophage inhibitory cytokine-1 is associated with cognitive impairment and predicts cognitive decline – The Sydney Memory and Aging Study', Neurology, Psychiatry and Brain Research, 20, pp. 9 - 9, http://dx.doi.org/10.1016/j.npbr.2014.01.145

Samaras K; Lutgers HL; Kochan NA; Crawford JD; Campbell LV; Wen W; Slavin MJ; Baune BT; Lipnicki DM; Brodaty H; Trollor JN; Sachdev PS, 2014, 'The impact of glucose disorders on cognition and brain volumes in the elderly: the Sydney Memory and Ageing Study', AGE, 36, pp. 977 - 993, http://dx.doi.org/10.1007/s11357-013-9613-0

Liu T; Sachdev PS; Lipnicki DM; Jiang J; Geng G; Zhu W; Reppermund S; Tao D; Trollor JN; Brodaty H; Wen W, 2013, 'Limited relationships between two-year changes in sulcal morphology and other common neuroimaging indices in the elderly', NeuroImage, 83, pp. 12 - 17, http://dx.doi.org/10.1016/j.neuroimage.2013.06.058

Sachdev PS; Lee T; Wen W; Ames D; Batouli AH; Bowden J; Brodaty H; Chong E; Crawford J; Kang K; Mather K; Lammel A; Slavin MJ; Thalamuthu A; Trollor J; Wright MJ; OATS Research Team ; Kumfor F; Kwok J; Menant J, 2013, 'The contribution of twins to the study of cognitive ageing and dementia: The Older Australian Twins Study', International Review of Psychiatry, 25, pp. 738 - 747, http://dx.doi.org/10.3109/09540261.2013.870137

Sachdev PS; Lipnicki DM; Kochan NA; Crawford JD; Reppermund S; Brodaty H; Rockwood K; Xiao S; Li X; Li J; Brayne C; Matthews FE; Stephan BCM; Lipton RB; Katz MJ; Ritchie K; Carrière I; Ancelin M-L; Seshadri S; Au R; Beiser AS; Lam LCW; Fung AWT; Wong CHY; Kim KW; Han JW; Kim TH; Petersen RC; Roberts RO; Mielke MM; Ganguli M; Hughes T; Dodge HH; Anstey KJ; Cherbuin N; Butterworth P; Ng TP; Gao Q; Meguro K; Schupf N; Manly J; Stern Y; Lobo A; Lopez-Anton R; Santabárbara J, 2013, 'COSMIC (Cohort Studies of Memory in an International Consortium): An international consortium to identify risk and protective factors and biomarkers of cognitive ageing and dementia in diverse ethnic and sociocultural groups', BMC Neurology, 13, pp. 165, http://dx.doi.org/10.1186/1471-2377-13-165

Kim J; Sachdev P; Sidhu K, 2013, 'Alginate microcapsule as a 3D platform for the efficient differentiation of human embryonic stem cells to dopamine neurons', Stem Cell Research, 11, pp. 978 - 989, http://dx.doi.org/10.1016/j.scr.2013.06.005

Anstey KJ; Bunce D; Bielak AAM; Cherbuin N; Batterham P; Wen W; Sachdev P, 2013, 'The utility of intraindividual reaction time variability measures to predict neuropathology in cognitively normal adults: A potential assessment tool for clinical contexts', Journal of the International Neuropsychological Society, 9, pp. 1 - 6, http://dx.doi.org/10.1017/S1355617713000830

Braidy N; Gai WP; Xu YH; Sachdev P; Guillemin GJ; Jiang XM; Ballard JWO; Horan MP; Fang ZM; Chong BH; Chan DKY, 2013, 'Uptake and mitochondrial dysfunction of alpha-synuclein in human astrocytes, cortical neurons and fibroblasts', Translational Neurodegeneration, 2, pp. 20, http://dx.doi.org/10.1186/2047-9158-2-20

Mortby ME; Janke AL; Anstey KJ; Sachdev PS; Cherbuin N, 2013, 'High "Normal" Blood Glucose Is Associated with Decreased Brain Volume and Cognitive Performance in the 60s: The PATH through Life Study', PLoS ONE, 8, pp. e73697, http://dx.doi.org/10.1371/journal.pone.0073697

Dong YH; Slavin MJ; Chan BPL; Venketasubramanian N; Sharma VK; Crawford JD; Collinson SL; Sachdev PS; Chen C, 2013, 'Cognitive screening improves the predictive value of stroke severity scores for functional outcome 3–6 months after mild stroke and transient ischemic attack: an observational study', BMJ Open, 3, pp. e003105 - e003105, http://dx.doi.org/10.1136/bmjopen-2013-003105

Chan HN; Alonzo A; Martin DM; Mitchell PB; Sachdev P; Loo CK, 2013, 'Augmenting transcranial direct current stimulation with D-cycloserine for depression: A pilot study', Journal of ECT, 29, pp. 196 - 200, http://dx.doi.org/10.1097/YCT.0b013e3182801b09

Quah-Smith I; Suo C; Sachdev P; Williams MA; Lundeberg T, 2013, 'Differential brain effects of laser and needle acupuncture at LR8 using functional MRI', Acupuncture in Medicine, 31, pp. 282 - 289, http://dx.doi.org/10.1136/acupmed-2012-010297

Mewton L; Sachdev PS; Andrews G, 2013, 'A Naturalistic Study of the Acceptability and Effectiveness of Internet-Delivered Cognitive Behavioural Therapy for Psychiatric Disorders in Older Australians', PLoS ONE, 8, pp. e71825, http://dx.doi.org/10.1371/journal.pone.0071825

Mewton L; Sachdev PS; Anderson T; Sunderland M; Andrews G; Sachdev P, 2013, 'Demographic, Clinical, and Lifestyle Correlates of Subjective Memory Complaints in the Australian Population', The American Journal of Geriatric Psychiatry, 22, pp. 1222 - 1232, http://dx.doi.org/10.1016/j.jagp.2013.04.004

Fuchs T; Trollor JN; Crawford J; Baune BT; Samaras K; Campbell L; Breit SN; Brodaty H; Sachdev P; Smith E; Brown D, 2013, 'Macrophage inhibitory cytokine-1 is associated with cognitive impairment and predicts cognitive decline – the Sydney Memory and Ageing Study', Aging Cell, 12, pp. 882 - 889, http://dx.doi.org/10.1111/acel.12116

Schilling S; DeStefano AL; Sachdev PS; Choi SH; Mather KA; DeCarli CD; Wen W; Høgh P; Raz N; Au R; Beiser A; Wolf PA; Romero JR; Zhu YC; Lunetta KL; Farrer L; Dufouil C; Kuller LH; Mazoyer B; Seshadri S; Tzourio C; Debette S, 2013, 'APOE genotype and MRI markers of cerebrovascular disease', Neurology, 81, pp. 292 - 300, http://dx.doi.org/10.1212/WNL.0b013e31829bfda4

Gates N; Sachdev ; Fiatarone Singh M; Valenzuela MV, 2013, 'The effects of exercise training on cognitive function in older adults with mild cognitive impairment: a meta-analysis', American Journal of Geriatric Psychiatry, 21, pp. 1086 - 1097, http://dx.doi.org/10.1016/j.jagp.2013.02.018

Yang Z; Slavin MJ; Sachdev PS, 2013, 'Dementia in the oldest old', Nature Reviews Neurology, 9, pp. 382 - 393, http://dx.doi.org/10.1038/nrneurol.2013.105

Gautam P; Cherbuin N; Sachdev PS; Wen W; Anstey KJ, 2013, 'Sex differences in cortical thickness in middle aged and early old-aged adults: Personality and Total Health Through Life study', Neuroradiology, 55, pp. 697 - 707, http://dx.doi.org/10.1007/s00234-013-1144-y

Martin DM; Liu R; Alonzo A; Green M; Player MJ; Sachdev PS; Loo CK, 2013, 'Can transcranial direct current stimulation enhance outcomes from cognitive training? A randomized controlled trial in healthy participants', International Journal of Neuropsychopharmacology, 16, pp. 1927 - 1936, http://dx.doi.org/10.1017/s1461145713000539

Funahashi Y; Penson RT; Powell MA; Miller DS; Fan J; Ren M; Meneses N; Sachdev P; Kadowaki T; O'Brien JP; Vergote I, 2013, 'Analysis of plasma biomarker and tumor genetic alterations from a phase II trial of lenvatinib in patients with advanced endometrial cancer.', Journal of Clinical Oncology, 31, pp. 5591 - 5591, http://dx.doi.org/10.1200/jco.2013.31.15_suppl.5591

Sachdev P; Hamid O; Kim K; Hauschild A; O'Day S; Andresen C; Funahashi Y; Kadowaki T; O'Brien JP; Flaherty K, 2013, 'Analysis of serum biomarkers and tumor genetic alterations from a phase II study of lenvatinib in patients with advanced BRAF wild-type melanoma.', Journal of Clinical Oncology, 31, pp. 9058 - 9058, http://dx.doi.org/10.1200/jco.2013.31.15_suppl.9058

Slavin MJ; Brodaty H; Sachdev PS, 2013, 'Challenges of diagnosing dementia in the oldest old population', Journal of Gerontology Series A: Biological Sciences and Medical Sciences, 68, pp. 1103 - 1111, http://dx.doi.org/10.1093/Gerona/glt051

Player MJ; Weickert CS; Alonzo A; Sachdev P; Martin D; Mitchell PB; Loo CK; Taylor JL, 2013, 'Neuroplasticity in Depressed Individuals Compared with Healthy Controls', Neuropsychopharmacology, 38, pp. 2101 - 2108, http://dx.doi.org/10.1038/npp.2013.126

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