Problem 1

Legislation

The Animal Research Act (1985) and Regulations (1995)

Available from: NSW Government Publications Internet:

Gene Technology Act

For information contact the Office of the Gene Technology Regulator
Internet: http://www.ogtr.gov.au

Codes of Practice

The Australian Code of Practice for the Care and Use of Animals for Scientific Purposes (1997)

Available from: Australian Government Publishing Services, GPO Box 84, Canberra. 2601
Internet: http://www.health.gov.au./nhmrc

Model Codes of Practice sponsored by the Agriculture and Resource Management Council of Australia and New Zealand (ARMCANZ) cover the transport, handling and husbandry of livestock.

Available from CSIRO Publishing, PO Box 1139, Collingwood, Victoria 3066.
Internet: http://www.publish.CSIRO.au

Policies & Guidelines

Animal Welfare Unit, NSW Agriculture

The Animal Research Review Panel publishes policies and guidelines which cover a range of situations and activities. Copies of all documents can be found at and down loaded from: www.agric.nsw.gov.au/Aw/index.html

Recommended texts and references

General

Fox, J.G., Cohen, B.J., Loew, F.M. (1984) Eds. Laboratory Animal Medicine. Academic Press. Orlando Florida, USA. ISN 0122636201.

Poole, T.B. (1999) Ed. UFAW Handbook on the Care and Management of Laboratory Animals. 7th Edition. (2 Vols) Blackwells Scientific & Technical, Harlow, UK.

Rose MA (1991) The Care and Use of Animals for Scientific Purpose. A Selected Bibliography. ANZCCART, Adelaide.

Van Zutphen L.F.M., Baumans, V., Beynen, A.C. Eds. Principles of Laboratory Animal Science - A Contribution to the Humane Use and Care of Animals and to the Quality of Experimental Results. Elsevier Science Publishers B.V., Amsterdam, The Netherlands. ISBN 0-444-81487-6.

Wester, J. (1994) Animal welfare -A Cool Eye Towards Eden. Blackwell Science Ltd. Oxford. UK.

Organisations

Animal ethics committees

  • Baker RM, Burrell JH, Rose MA Eds. (1994) Effective Animal Experimentation Ethics Committees. ANZCCART, Adelaide.

  • Rose MA (1996) Striking the balance: the practitioner and the animal ethics committee. ANZCCART News, 9: 1-3.

The 3R’s

  • Balls M (1994) Replacement of animal procedures : alternatives in research, education, and testing. Laboratory Animals 28: 193-211.

  • Festing MFW (1994) Reduction of animal use: experimental design and quality of experiments . Laboratory Animals 28: 212-221.

  • Flecknell PA (1994) Refinement of animal use- assessment and alleviation of pain and distress. Laboratory Animals 28: 222-231.

  • Rose MA (1992) Russell and Burch revisited. ANZCCART NEWS. 5: 1-7.

  • Russell, W.M.S., Burch, R.L. (1992) The Principles of Humane Experimental Technique.2nd.Ed. Methuen, London,UK. ISBN 0900767782.

Animal models

  • FELASA (1999)Laboratory animal health monitoring (1999) Laboratory Animals 33 Supplement 1 Copies available from website http: //www.lal.org.uk

  • Gay, W.I. (1965-86) Ed. Methods of Animal Experimentation. Vols 1 - 7. Academic Press, New York. USA.

  • Loeb, W.F., Quimby, F.W. (1988) Eds. Clinical Chemistry of Laboratory Animals. Pergamon Press, New York. USA.

  • Kawamata J., Melby EC Eds. (1987) Animal Models: Assessing the Scope of Their Use in Biomedical Research. Alan R.Liss, New York.

  • Mitruka, E.D., Rawnsley, H.M. (1979) Clinical Biochemical and Haematological Reference Values in Normal Experimental Animals. Masson Publ. New York.USA.

  • National Research Council (1991) Infectious Diseases of Mice and Rats. National Academy Press, Washington DC.

  • National Research Council Committee on Models for Biomedical Research (1985) Models for Biomedical Research: A New Perspective. National Academy Press, Washington DC.

  • Tyndale-Biscoe CH, Janssens PA (1988) The Developing Marsupial: Models for Biomedical Research. Springer-Verlag, Berlin/New York.

  • van Zutphen LFM, ban der Meer M (1996) Welfare Aspects of Transgenic Animals. Springer-Verlag, Berlin.

  • National Institutes of Health website: www.nih.gov/science/models

  • Transgenic Animal Web; www.med.umich.edu/tamc

  • Gene Knockout mice database; www.bioscience.org/knockout

  • Jackson Laboratories www.informatics.jax.org and tbase.jax.org

  • MRC Mammalian Genetics Unitwww.mgu.har.mrc.ac.uk and tbase.jax.org

Environmental conditions

  • Baker RM, Jenkin G., Mellor DJ Eds. (1994) Improving the Well-being of Animals in the Research Environment. ANZCCART. Adelaide.

  • Clough G. (1982) Environmental effects on animals used in biomedical research. Biological Reviews, 57: 487-523.

  • Gamble, MR (1982) Sound and its significance for laboratory animals. Biological Reviews, 57: 395-421.

  • Annotated database on Refinement of Housing and Handling Conditions and Environmental Enrichment for Laboratory Animals; www.awionline.org/lab_animals/bibliio/refine.htm

Euthanasia

  • AVMA (2000) Report of the American Veterinary Association Panel on euthanasia. Journal of the Veterinary Medical Association, 218: 669-696 :www.avma.org/resources/euthanasia.pdf

  • LASA (1996/97) Recommendations for euthanasia of experimental animals, Laboratory Animals, 30: 293-316; 31: 1-32. Copies available from website http: //www.lal.org.uk

  • Reilly JS Ed.(2001) Euthanasia of Animals Used for Scientific Purposes. ANZCCART, Adelaide.

  • UFAW/WSPCA (1989) Euthanasia of Amphibians and Reptiles. UFAW, Potters Bar Herts. UK.

Monitoring animal welfare

  • Barclay RJ (1988) The Disturbance Index: A Behavioural Method of Assessing the Severity of Common Laboratory Procedures on Rodents. UFAW, Potters Bar Herts.UK.

  • Lynch JJ, Hinch G,Adams DB (1992) Behaviour of Sheep: Biological Principles and Implications for Production. CSIRO Australia & CAB UK.

  • Mason G, Mendl M (1993) Why isn’t there a simple way of measuring animal welfare? Animal Welfare 2: 301-319.

  • Morton DB., Griffiths PHM (1985) Guidelines on the recognition of pain, distress and discomfort in experimental animals and an hypothesis for assessment. Veterinary Record, 116: 431-436.

Website on assessment of animal welfare: www.vetinfo.demon.nl/aw/index.html

Return to the top of the page