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Aggarwal A, Stella AO, Walker G, Akerman A, Esneau C, Milogiannakis V, Burnett DL, McAllery S, Silva MR, Lu Y, Foster CSP, Brilot F, Pillay A, Van Hal S, Mathivanan V, Fichter C, Kindinger A, Hoppe AC, Munier ML, Amatayakul-Chantler S, Roth N, Coppola G, Symonds GP, Schofield P, Jackson J, Lenthall H, Henry JY, Mazigi O, Jäck HM, Davenport MP, Darley DR, Matthews GV, Khoury DS, Cromer D, Goodnow CC, Christ D, Robosa R, Starck DJ, Bartlett NW, Rawlinson WD, Kelleher AD, Turville SG. Platform for isolation and characterization of SARS-CoV-2 variants enables rapid characterization of Omicron in Australia. Nat Microbiol. 2022 Jun;7(6):896-908. doi: 10.1038/s41564-022-01135-7. Epub 2022 May 30. PMID: 35637329; PMCID: PMC9159941. |
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Daniszewski M, Senabouth A, Liang HH, Han X, Lidgerwood GE, Hernández D, Sivakumaran P, Clarke JE, Lim SY, Lees JG, Rooney L, Gulluyan L, Souzeau E, Graham SL, Chan CL, Nguyen U, Farbehi N, Gnanasambandapillai V, McCloy RA, Clarke L, Kearns LS, Mackey DA, Craig JE, MacGregor S, Powell JE, Pébay A, Hewitt AW. Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma. Cell Genom. 2022 Jun 8;2(6):100142. doi: 10.1016/j.xgen.2022.100142. PMID: 36778138; PMCID: PMC9903700. |
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Herring CA, Simmons RK, Freytag S, Poppe D, Moffet JJD, Pflueger J, Buckberry S, Vargas-Landin DB, Clément O, Echeverría EG, Sutton GJ, Alvarez-Franco A, Hou R, Pflueger C, McDonald K, Polo JM, Forrest ARR, Nowak AK, Voineagu I, Martelotto L, Lister R. Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution. Cell. 2022 Nov 10;185(23):4428-4447.e28. doi: 10.1016/j.cell.2022.09.039. Epub 2022 Oct 31. PMID: 36318921. |
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Ho WJ, Law AMK, Masle-Farquhar E, Castillo LE, Mawson A, O'Bryan MK, Goodnow CC, Gallego-Ortega D, Oakes SR, Ormandy CJ. Activation of the viral sensor oligoadenylate synthetase 2 (Oas2) prevents pregnancy-driven mammary cancer metastases. Breast Cancer Res. 2022 May 3;24(1):31. doi: 10.1186/s13058-022-01525-z. PMID: 35505346; PMCID: PMC9066770. |
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Langley DB, Schofield P, Nevoltris D, Jackson J, Jackson KJL, Peters TJ, Burk M, Matthews JM, Basten A, Goodnow CC, van Nunen S, Reed JH, Christ D. Genetic and structural basis of the human anti-α-galactosyl antibody response. Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2123212119. doi: 10.1073/pnas.2123212119. Epub 2022 Jul 8. PMID: 35867757; PMCID: PMC9282431. |
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Masle-Farquhar E, Jackson KJL, Peters TJ, Al-Eryani G, Singh M, Payne KJ, Rao G, Avery DT, Apps G, Kingham J, Jara CJ, Skvortsova K, Swarbrick A, Ma CS, Suan D, Uzel G, Chua I, Leiding JW, Heiskanen K, Preece K, Kainulainen L, O'Sullivan M, Cooper MA, Seppänen MRJ, Mustjoki S, Brothers S, Vogel TP, Brink R, Tangye SG, Reed JH, Goodnow CC. STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation. Immunity. 2022 Dec 13;55(12):2386-2404.e8. doi: 10.1016/j.immuni.2022.11.001. Epub 2022 Nov 28. PMID: 36446385. |
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Masle-Farquhar E, Peters TJ, Miosge LA, Parish IA, Weigel C, Oakes CC, Reed JH, Goodnow CC. Uncontrolled CD21low age-associated and B1 B cell accumulation caused by failure of an EGR2/3 tolerance checkpoint. Cell Rep. 2022 Jan 18;38(3):110259. doi: 10.1016/j.celrep.2021.110259. PMID: 35045301. |
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Nüssing S, Miosge LA, Lee K, Olshansky M, Barugahare A, Roots CM, Sontani Y, Day EB, Koutsakos M, Kedzierska K, Goodnow CC, Russ BE, Daley SR, Turner SJ. SATB1 ensures appropriate transcriptional programs within naïve CD8+ T cells. Immunol Cell Biol. 2022 Sep;100(8):636-652. doi: 10.1111/imcb.12566. Epub 2022 Jul 13. PMID: 35713361; PMCID: PMC9542893. |
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Patel B, Kleeman SO, Neavin D, Powell J, Baskozos G, Ng M, Ahmed WU, Bennett DL, Schmid AB, Furniss D, Wiberg A. Shared genetic susceptibility between trigger finger and carpal tunnel syndrome: a genome-wide association study. Lancet Rheumatol. 2022 Aug;4(8):e556-e565. doi: 10.1016/S2665-9913(22)00180-1. PMID: 36043126; PMCID: PMC7613465. |
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Pelham SJ, Caldirola MS, Avery DT, Mackie J, Rao G, Gothe F, Peters TJ, Guerin A, Neumann D, Vokurkova D, Hwa V, Zhang W, Lyu SC, Chang I, Manohar M, Nadeau KC, Gaillard MI, Bezrodnik L, Iotova V, Zwirner NW, Gutierrez M, Al-Herz W, Goodnow CC, Vargas-Hernández A, Forbes Satter LR, Hambleton S, Deenick EK, Ma CS, Tangye SG. STAT5B restrains human B-cell differentiation to maintain humoral immune homeostasis. J Allergy Clin Immunol. 2022 Oct;150(4):931-946. doi: 10.1016/j.jaci.2022.04.011. Epub 2022 Apr 22. PMID: 35469842. |
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Phipson B, Sim CB, Porrello ER, Hewitt AW, Powell J, Oshlack A. propeller: testing for differences in cell type proportions in single cell data. Bioinformatics. 2022 Oct 14;38(20):4720-4726. doi: 10.1093/bioinformatics/btac582. PMID: 36005887; PMCID: PMC9563678. |
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Putri GH, Anders S, Pyl PT, Pimanda JE, Zanini F. Analysing high-throughput sequencing data in Python with HTSeq 2.0. Bioinformatics. 2022 May 13;38(10):2943-2945. doi: 10.1093/bioinformatics/btac166. PMID: 35561197; PMCID: PMC9113351. |
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Schulz SR, Hoffmann M, Roth E, Pracht K, Burnett DL, Mazigi O, Schuh W, Manger B, Mielenz D, Goodnow CC, Christ D, Pöhlmann S, Jäck HM. Augmented neutralization of SARS-CoV-2 Omicron variant by boost vaccination and monoclonal antibodies. Eur J Immunol. 2022 Jun;52(6):970-977. doi: 10.1002/eji.202249841. Epub 2022 Mar 23. PMID: 35253229; PMCID: PMC9087419. |
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Senabouth A, Daniszewski M, Lidgerwood GE, Liang HH, Hernández D, Mirzaei M, Keenan SN, Zhang R, Han X, Neavin D, Rooney L, Lopez Sanchez MIG, Gulluyan L, Paulo JA, Clarke L, Kearns LS, Gnanasambandapillai V, Chan CL, Nguyen U, Steinmann AM, McCloy RA, Farbehi N, Gupta VK, Mackey DA, Bylsma G, Verma N, MacGregor S, Watt MJ, Guymer RH, Powell JE, Hewitt AW, Pébay A. Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration. Nat Commun. 2022 Jul 26;13(1):4233. doi: 10.1038/s41467-022-31707-4. PMID: 35882847; PMCID: PMC9325891. |
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Wang J, Weatheritt R, Voineagu I. Alu-minating the Mechanisms Underlying Primate Cortex Evolution. Biol Psychiatry. 2022 Nov 15;92(10):760-771. doi: 10.1016/j.biopsych.2022.04.021. Epub 2022 May 19. PMID: 35981906. |
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Wilson SB, Howden SE, Vanslambrouck JM, Dorison A, Alquicira-Hernandez J, Powell JE, Little MH. DevKidCC allows for robust classification and direct comparisons of kidney organoid datasets. Genome Med. 2022 Feb 22;14(1):19. doi: 10.1186/s13073-022-01023-z. PMID: 35189942; PMCID: PMC8862535. |
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Yang R, Avery DT, Jackson KJL, Ogishi M, Benhsaien I, Du L, Ye X, Han J, Rosain J, Peel JN, Alyanakian MA, Neven B, Winter S, Puel A, Boisson B, Payne KJ, Wong M, Russell AJ, Mizoguchi Y, Okada S, Uzel G, Goodnow CC, Latour S, El Bakkouri J, Bousfiha A, Preece K, Gray PE, Keller B, Warnatz K, Boisson-Dupuis S, Abel L, Pan-Hammarström Q, Bustamante J, Ma CS, Casanova JL, Tangye SG. Human T-bet governs the generation of a distinct subset of CD11chighCD21low B cells. Sci Immunol. 2022 Jul 22;7(73):eabq3277. doi: 10.1126/sciimmunol.abq3277. Epub 2022 Jul 22. PMID: 35867801; PMCID: PMC9413977. |
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Yazar S, Alquicira-Hernandez J, Wing K, Senabouth A, Gordon MG, Andersen S, Lu Q, Rowson A, Taylor TRP, Clarke L, Maccora K, Chen C, Cook AL, Ye CJ, Fairfax KA, Hewitt AW, Powell JE. Single-cell eQTL mapping identifies cell type-specific genetic control of autoimmune disease. Science. 2022 Apr 8;376(6589):eabf3041. doi: 10.1126/science.abf3041. Epub 2022 Apr 8. PMID: 35389779. |
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Yazar S, Powell JE. Single-cell expression Quantitative Trait Loci: T-cell immunology teams up with statistical genetics. Immunol Cell Biol. 2022 Sep;100(8):588-590. doi: 10.1111/imcb.12577. Epub 2022 Aug 8. PMID: 35866982. |
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Zammit NW, McDowell J, Warren J, Muskovic W, Gamble J, Shi YC, Kaczorowski D, Chan CL, Powell J, Ormandy C, Brown D, Oakes SR, Grey ST. TNFAIP3 Reduction-of-Function Drives Female Infertility and CNS Inflammation. Front Immunol. 2022 Apr 8;13:811525. doi: 10.3389/fimmu.2022.811525. PMID: 35464428; PMCID: PMC9027572. |
| 1 | Alquicira-Hernandez J, Powell JE, Phan TG. No evidence that plasmablasts transdifferentiate into developing neutrophils in severe COVID-19 disease. Clin Transl Immunology. 2021 Jun 30;10(7):e1308. doi: 10.1002/cti2.1308. PMID: 34221402; PMCID: PMC8245277. |
| 2 | Alquicira-Hernandez J, Powell JE. Nebulosa recovers single cell gene expression signals by kernel density estimation. Bioinformatics. 2021 Jan 18:btab003. doi: 10.1093/bioinformatics/btab003. Epub ahead of print. PMID: 33459785 |
| 3 | Boast B, Miosge LA, Kuehn HS, Cho V, Athanasopoulos V, McNamara HA, Sontani Y, Mei Y, Howard D, Sutton HJ, Omari SA, Yu Z, Nasreen M, Andrews TD, Cockburn IA, Goodnow CC, Rosenzweig SD, Enders A. A Point Mutation in IKAROS ZF1 Causes a B Cell Deficiency in Mice. J Immunol. 2021 Apr 1;206(7):1505-1514. doi: 10.4049/jimmunol.1901464. Epub 2021 Mar 3. PMID: 33658297; PMCID: PMC7987828. |
| 4 | Bui LT, Winters NI, Chung MI, Joseph C, Gutierrez AJ, Habermann AC, Adams TS, Schupp JC, Poli S, Peter LM, Taylor CJ, Blackburn JB, Richmond BW, Nicholson AG, Rassl D, Wallace WA, Rosas IO, Jenkins RG, Kaminski N, Kropski JA, Banovich NE; Human Cell Atlas Lung Biological Network. Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity. Nat Commun. 2021 Jul 14;12(1):4314. doi: 10.1038/s41467-021-24467-0. PMID: 34262047; PMCID: PMC8280215 |
| 5 | Burnett DL, Jackson KJL, Langley DB, Aggrawal A, Stella AO, Johansen MD, Balachandran H, Lenthall H, Rouet R, Walker G, Saunders BM, Singh M, Li H, Henry JY, Jackson J, Stewart AG, Witthauer F, Spence MA, Hansbro NG, Jackson C, Schofield P, Milthorpe C, Martinello M, Schulz SR, Roth E, Kelleher A, Emery S, Britton WJ, Rawlinson WD, Karl R, Schäfer S, Winkler TH, Brink R, Bull RA, Hansbro PM, Jäck HM, Turville S, Christ D, Goodnow CC. Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability. Immunity. 2021 Dec 14;54(12):2908-2921.e6. doi: 10.1016/j.immuni.2021.10.019. Epub 2021 Oct 29. PMID: 34788600; PMCID: PMC8554075. |
| 6 | Cohen J, Blumenthal A, Cuellar-Partida G, Evans DM, Finfer S, Li Q, Ljungberg J, Myburgh J, Peach E, Powell J, Rajbhandari D, Rhodes A, Senabouth A, Venkatesh B. The relationship between adrenocortical candidate gene expression and clinical response to hydrocortisone in patients with septic shock. Intensive Care Med. 2021 Sep;47(9):974-983. doi: 10.1007/s00134-021-06464-5. Epub 2021 Jun 29. PMID: 34185116. |
| 7 | Currant H, Hysi P, Fitzgerald TW, Gharahkhani P, Bonnemaijer PWM, Senabouth A, Hewitt AW; UK Biobank Eye and Vision Consortium, International Glaucoma Genetics Consortium, Atan D, Aung T, Charng J, Choquet H, Craig J, Khaw PT, Klaver CCW, Kubo M, Ong JS, Pasquale LR, Reisman CA, Daniszewski M, Powell JE, Pébay A, Simcoe MJ, Thiadens AAHJ, van Duijn CM, Yazar S, Jorgenson E, MacGregor S, Hammond CJ, Mackey DA, Wiggs JL, Foster PJ, Patel PJ, Birney E, Khawaja AP. Correction: Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images. PLoS Genet. 2021 Oct 18;17(10):e1009858. doi: 10.1371/journal.pgen.1009858. Erratum for: PLoS Genet. 2021 May 12;17(5):e1009497. PMID: 34662343; PMCID: PMC8523050. |
| 8 | Du Q, Smith GC, Luu PL, Ferguson JM, Armstrong NJ, Caldon CE, Campbell EM, Nair SS, Zotenko E, Gould CM, Buckley M, Chia KM, Portman N, Lim E, Kaczorowski D, Chan CL, Barton K, Deveson IW, Smith MA, Powell JE, Skvortsova K, Stirzaker C, Achinger-Kawecka J, Clark SJ. DNA methylation is required to maintain both DNA replication timing precision and 3D genome organization integrity. Cell Rep. 2021 Sep 21;36(12):109722. doi: 10.1016/j.celrep.2021.109722. PMID: 34551299. |
| 9 | Goodnow CC. COVID-19, varying genetic resistance to viral disease and immune tolerance checkpoints. Immunol Cell Biol. 2021 Feb;99(2):177-191. doi: 10.1111/imcb.12419. Epub 2020 Nov 23. PMID: 33113212; PMCID: PMC7894315. |
| 10 | Hemani G, Powell JE, Wang H, Shakhbazov K, Westra HJ, Esko T, Henders AK, McRae AF, Martin NG, Metspalu A, Franke L, Montgomery GW, Goddard ME, Gibson G, Yang J, Visscher PM. Phantom epistasis between unlinked loci. Nature. 2021 Aug;596(7871):E1-E3. doi: 10.1038/s41586-021-03765-z. Epub 2021 Aug 11. PMID: 34381229. |
| 11 | Kayagaki N, Kornfeld OS, Lee BL, Stowe IB, O'Rourke K, Li Q, Sandoval W, Yan D, Kang J, Xu M, Zhang J, Lee WP, McKenzie BS, Ulas G, Payandeh J, Roose-Girma M, Modrusan Z, Reja R, Sagolla M, Webster JD, Cho V, Andrews TD, Morris LX, Miosge LA, Goodnow CC, Bertram EM, Dixit VM. NINJ1 mediates plasma membrane rupture during lytic cell death. Nature. 2021 Mar;591(7848):131-136. doi: 10.1038/s41586-021-03218-7. Epub 2021 Jan 20. PMID: 33472215. |
| 12 | Lidgerwood GE, Senabouth A, Smith-Anttila CJA, Gnanasambandapillai V, Kaczorowski DC, Amann-Zalcenstein D, Fletcher EL, Naik SH, Hewitt AW, Powell JE, Pébay A. Transcriptomic Profiling of Human Pluripotent Stem Cell-derived Retinal Pigment Epithelium over Time. Genomics Proteomics Bioinformatics. 2021 Apr;19(2):223-242. doi: 10.1016/j.gpb.2020.08.002. Epub 2020 Dec 8. PMID: 33307245; PMCID: PMC8602392. |
| 13 | Muir AM, Gardner JF, van Jaarsveld RH, de Lange IM, van der Smagt JJ, Wilson GN, Dubbs H, Goldberg EM, Zitano L, Bupp C, Martinez J, Srour M, Accogli A, Alhakeem A, Meltzer M, Gropman A, Brewer C, Caswell RC, Montgomery T, McKenna C, McKee S, Powell C, Vasudevan PC, Brady AF, Joss S, Tysoe C, Noh G, Tarnopolsky M, Brady L, Zafar M, Schrier Vergano SA, Murray B, Sawyer L, Hainline BE, Sapp K, DeMarzo D, Huismann DJ, Wentzensen IM, Schnur RE, Monaghan KG, Juusola J, Rhodes L, Dobyns WB, Lecoquierre F, Goldenberg A, Polster T, Axer-Schaefer S, Platzer K, Klöckner C, Hoffman TL, MacArthur DG, O'Leary MC, VanNoy GE, England E, Varghese VC, Mefford HC. Variants in GNAI1 cause a syndrome associated with variable features including developmental delay, seizures, and hypotonia. Genet Med. 2021 May;23(5):881-887. doi: 10.1038/s41436-020-01076-8. Epub 2021 Jan 20. PMID: 33473207; PMCID: PMC8107131. |
| 14 | Muskovic, W., Powell, J.E. DropletQC: improved identification of empty droplets and damaged cells in single-cell RNA-seq data. Genome Biol 22, 329 (2021). https://doi.org/10.1186/s13059-021-02547-0 |
| 15 | Muus C, Luecken MD, Eraslan G, Sikkema L, Waghray A, Heimberg G, Kobayashi Y, Vaishnav ED, Subramanian A, Smillie C, Jagadeesh KA, Duong ET, Fiskin E, Torlai Triglia E, Ansari M, Cai P, Lin B, Buchanan J, Chen S, Shu J, Haber AL, Chung H, Montoro DT, Adams T, Aliee H, Allon SJ, Andrusivova Z, Angelidis I, Ashenberg O, Bassler K, Bécavin C, Benhar I, Bergenstråhle J, Bergenstråhle L, Bolt L, Braun E, Bui LT, Callori S, Chaffin M, Chichelnitskiy E, Chiou J, Conlon TM, Cuoco MS, Cuomo ASE, Deprez M, Duclos G, Fine D, Fischer DS, Ghazanfar S, Gillich A, Giotti B, Gould J, Guo M, Gutierrez AJ, Habermann AC, Harvey T, He P, Hou X, Hu L, Hu Y, Jaiswal A, Ji L, Jiang P, Kapellos TS, Kuo CS, Larsson L, Leney-Greene MA, Lim K, Litviňuková M, Ludwig LS, Lukassen S, Luo W, Maatz H, Madissoon E, Mamanova L, Manakongtreecheep K, Leroy S, Mayr CH, Mbano IM, McAdams AM, Nabhan AN, Nyquist SK, Penland L, Poirion OB, Poli S, Qi C, Queen R, Reichart D, Rosas I, Schupp JC, Shea CV, Shi X, Sinha R, Sit RV, Slowikowski K, Slyper M, Smith NP, Sountoulidis A, Strunz M, Sullivan TB, Sun D, Talavera-López C, Tan P, Tantivit J, Travaglini KJ, Tucker NR, Vernon KA, Wadsworth MH, Waldman J, Wang X, Xu K, Yan W, Zhao W, Ziegler CGK; NHLBI LungMap Consortium; Human Cell Atlas Lung Biological Network. Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics. Nat Med. 2021 Mar;27(3):546-559. doi: 10.1038/s41591-020-01227-z. Epub 2021 Mar 2. PMID: 33654293. |
| 16 | Neavin D, Nguyen Q, Daniszewski MS, Liang HH, Chiu HS, Wee YK, Senabouth A, Lukowski SW, Crombie DE, Lidgerwood GE, Hernández D, Vickers JC, Cook AL, Palpant NJ, Pébay A, Hewitt AW, Powell JE. Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells. Genome Biol. 2021 Mar 5;22(1):76. doi: 10.1186/s13059-021-02293-3. PMID: 33673841; PMCID: PMC7934233. |
| 17 | Nieto P, Elosua-Bayes M, Trincado JL, Marchese D, Massoni-Badosa R, Salvany M, Henriques A, Nieto J, Aguilar-Fernández S, Mereu E, Moutinho C, Ruiz S, Lorden P, Chin VT, Kaczorowski D, Chan CL, Gallagher R, Chou A, Planas-Rigol E, Rubio-Perez C, Gut I, Piulats JM, Seoane J, Powell JE, Batlle E, Heyn H. A single-cell tumor immune atlas for precision oncology. Genome Res. 2021 Oct;31(10):1913-1926. doi: 10.1101/gr.273300.120. Epub 2021 Sep 21. PMID: 34548323; PMCID: PMC8494216. |
| 18 | Palgen JL, Feraoun Y, Dzangué-Tchoupou G, Joly C, Martinon F, Le Grand R, Beignon AS. Optimize Prime/Boost Vaccine Strategies: Trained Immunity as a New Player in the Game. Front Immunol. 2021 Mar 8;12:612747. doi: 10.3389/fimmu.2021.612747. PMID: 33763063; PMCID: PMC7982481. |
| 19 | Peters TJ, Buckley MJ, Chen Y, Smyth GK, Goodnow CC, Clark SJ. Calling differentially methylated regions from whole genome bisulphite sequencing with DMRcate. Nucleic Acids Res. 2021 Nov 8;49(19):e109. doi: 10.1093/nar/gkab637. PMID: 34320181; PMCID: PMC8565305. |
| 20 | Randall KL, Law HD, Ziolkowski AF, Wirasinha RC, Goodnow CC, Daley SR. DOCK8 deficiency diminishes thymic T-regulatory cell development but not thymic deletion. Clin Transl Immunology. 2021 Jan 7;10(1):e1236. doi: 10.1002/cti2.1236. PMID: 33437483; PMCID: PMC7790591. |
| 21 | Russell AJ, Gray PE, Ziegler JB, Kim YJ, Smith S, Sewell WA, Goodnow CC. SAMD9L autoinflammatory or ataxia pancytopenia disease mutations activate cell-autonomous translational repression. Proc Natl Acad Sci U S A. 2021 Aug 24;118(34):e2110190118. doi: 10.1073/pnas.2110190118. PMID: 34417303; PMCID: PMC8403910. |
| 22 | Shen S, Sun Y, Matsumoto M, Shim WJ, Sinniah E, Wilson SB, Werner T, Wu Z, Bradford ST, Hudson J, Little MH, Powell J, Nguyen Q, Palpant NJ. Integrating single-cell genomics pipelines to discover mechanisms of stem cell differentiation. Trends Mol Med. 2021 Dec;27(12):1135-1158. doi: 10.1016/j.molmed.2021.09.006. Epub 2021 Oct 14. PMID: 34657800. |
| 23 | Shparberg R, Dewi CU, Gnanasambandapillai V, Liyanage L, O'Connor MD. Single cell RNA-sequencing data generated from human pluripotent stem cell-derived lens epithelial cells. Data Brief. 2021 Jan 8;34:106657. doi: 10.1016/j.dib.2020.106657. PMID: 33521174; PMCID: PMC7820909. |
| 24 | Sinclair KA, Yerkovich ST, Hopkins PM, Fieuw AM, Ford P, Powell JE, O'Sullivan B, Chambers DC. The autotaxin-lysophosphatidic acid pathway mediates mesenchymal cell recruitment and fibrotic contraction in lung transplant fibrosis. J Heart Lung Transplant. 2021 Jan;40(1):12-23. doi: 10.1016/j.healun.2020.10.005. Epub 2020 Oct 22. PMID: 33339555. |
| 25 | Thompson M, Matsumoto M, Ma T, Senabouth A, Palpant NJ, Powell JE, Nguyen Q. scGPS: Determining Cell States and Global Fate Potential of Subpopulations. Front Genet. 2021 Jul 19;12:666771. doi: 10.3389/fgene.2021.666771. PMID: 34349778; PMCID: PMC8326972 |
| 26 | Tuong ZK, Lukowski SW, Nguyen QH, Chandra J, Zhou C, Gillinder K, Bashaw AA, Ferdinand JR, Stewart BJ, Teoh SM, Hanson SJ, Devitt K, Clatworthy MR, Powell JE, Frazer IH. A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasia. iScience. 2021 Oct 21;24(11):103326. doi: 10.1016/j.isci.2021.103326. PMID: 34805788; PMCID: PMC8586807. |
| 27 | van der Wijst M, de Vries DH, Groot HE, Trynka G, Hon CC, Bonder MJ, Stegle O, Nawijn MC, Idaghdour Y, van der Harst P, Ye CJ, Powell J, Theis FJ, Mahfouz A, Heinig M, Franke L. The single-cell eQTLGen consortium. Elife. 2020 Mar 9;9:e52155. doi: 10.7554/eLife.52155. PMID: 32149610; PMCID: PMC7077978. |
| 28 | Võsa U, Claringbould A, Westra HJ, Bonder MJ, Deelen P, Zeng B, Kirsten H, Saha A, Kreuzhuber R, Yazar S, Brugge H, Oelen R, de Vries DH, van der Wijst MGP, Kasela S, Pervjakova N, Alves I, Favé MJ, Agbessi M, Christiansen MW, Jansen R, Seppälä I, Tong L, Teumer A, Schramm K, Hemani G, Verlouw J, Yaghootkar H, Sönmez Flitman R, Brown A, Kukushkina V, Kalnapenkis A, Rüeger S, Porcu E, Kronberg J, Kettunen J, Lee B, Zhang F, Qi T, Hernandez JA, Arindrarto W, Beutner F; BIOS Consortium; i2QTL Consortium, Dmitrieva J, Elansary M, Fairfax BP, Georges M, Heijmans BT, Hewitt AW, Kähönen M, Kim Y, Knight JC, Kovacs P, Krohn K, Li S, Loeffler M, Marigorta UM, Mei H, Momozawa Y, Müller-Nurasyid M, Nauck M, Nivard MG, Penninx BWJH, Pritchard JK, Raitakari OT, Rotzschke O, Slagboom EP, Stehouwer CDA, Stumvoll M, Sullivan P, 't Hoen PAC, Thiery J, Tönjes A, van Dongen J, van Iterson M, Veldink JH, Völker U, Warmerdam R, Wijmenga C, Swertz M, Andiappan A, Montgomery GW, Ripatti S, Perola M, Kutalik Z, Dermitzakis E, Bergmann S, Frayling T, van Meurs J, Prokisch H, Ahsan H, Pierce BL, Lehtimäki T, Boomsma DI, Psaty BM, Gharib SA, Awadalla P, Milani L, Ouwehand WH, Downes K, Stegle O, Battle A, Visscher PM, Yang J, Scholz M, Powell J, Gibson G, Esko T, Franke L. Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. Nat Genet. 2021 Sep;53(9):1300-1310. doi: 10.1038/s41588-021-00913-z. Epub 2021 Sep 2. PMID: 34475573; PMCID: PMC8432599. |
| 29 | Wagle MV, Vervoort SJ, Kelly MJ, Van Der Byl W, Peters TJ, Martin BP, Martelotto LG, Nüssing S, Ramsbottom KM, Torpy JR, Knight D, Reading S, Thia K, Miosge LA, Howard DR, Gloury R, Gabriel SS, Utzschneider DT, Oliaro J, Powell JD, Luciani F, Trapani JA, Johnstone RW, Kallies A, Goodnow CC, Parish IA. Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance. Nat Commun. 2021 May 13;12(1):2782. doi: 10.1038/s41467-021-23044-9. PMID: 33986293; PMCID: PMC8119420. |
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| 34 | Zhang Z, Jara CJ, Singh M, Xu H, Goodnow CC, Jackson KJ, Reed JH. Human transitional and IgMlow mature naïve B cells preserve permissive B-cell receptors. Immunol Cell Biol. 2021 Sep;99(8):865-878. doi: 10.1111/imcb.12478. Epub 2021 Jun 4. PMID: 33988890; PMCID: PMC8453828. |
| 1 | Avila Cobos, F, Alquicira-Hernandez, J, Powell, JE*. et al. Benchmarking of cell type deconvolution pipelines for transcriptomics data. Nat Commun 11, 5650, 2020 Nov 4. doi: 10.1038/s41467-020-19015-1. *co-senior |
| 2 | Ballouz, S, Mangala, MM, Perry, MD, Heitmann, S, Gillis, J, Hill, AP, Vandenberg, JI. Co-expression of calcium and herG potassium channels reduces the incidence of proarrhythmic events. Cardiovascular Research. Cardiovascular Research. 2020 Oct 1; cvaa280. doi: 10.1093/cvr/cvaa280. |
| 3 | Ballouz, S. Single‐Cell Transcriptomics. In eLS, John Wiley & Sons, Ltd (Ed.). 2020 Feb 17; doi:10.1002/9780470015902.a0028528. |
| 4 | Burnett, D. L.; Schofield, P.; Langley, D. B.; Jackson, J.; Bourne, K.; Wilson, E.; Porebski, B. T.; Buckle, A. M.; Brink, R.; Goodnow, C. C.; Christ, D. Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens PNAS 117 (36) :22341-22350, 2020 DOI: https://doi.org/10.1073/pnas.2005102117 |
| 5 | Byrne AJ, Powell JE, O'Sullivan BJ, Ogger PP, Hoffland A, Cook J, Bonner KL, Hewitt RJ, Wolf S, Ghai P, Walker SA, Lukowski SW, Molyneaux PL, Saglani S, Chambers DC, Maher TM, Lloyd CM. Dynamics of human monocytes and airway macrophages during healthy aging and after transplant. J Exp Med. 2020 Mar 2;217(3). DOI: 10.1084/jem.20191236 |
| 6 | Duffy AM, Halaki M, Spigelman A, Chin V, Gallagher RM, Flood VM. Nutritional parameters associated with hospital admissions in patients being treated for head and neck cancer. Supportive Care in Cancer. 2020 Jan 1;28(1):341-9. DOI: 10.1007/s00520-019-04826-w |
| 7 | Engel J, Lee H, Williams C, Kuns R, Olver S, Lansink L, Soon M, Andersen S, Powell J, Svensson V, Teichmann S, Hill G, Varelias A, Koyama M, Haque A. Single cell transcriptomics of allo-reactive CD4+ T cells over time reveals divergent fates during gut GVHD. JCI Insight. 2020; 5(13) doi: https://doi.org/10.1172/jci.insight.137990. |
| 8 | Fernández-Rodríguez J, Morales La Madrid A, Gel B, Castañeda Heredia A, Salvador H, Martínez-Iniesta M, Moutinho C, Morata J, Heyn H, Blanco I, Creus-Bachiller E, Capella G, Farré L, Vidal A, Soldado F, Krauel L, Suñol M, Serra E, Villanueva A, Lázaro C. Use of patient derived orthotopic xenograft models for real-time therapy guidance in a pediatric sporadic malignant peripheral nerve sheath tumor. Ther Adv Med Oncol. 2020 Jul 3;12:1758835920929579. doi: 10.1177/1758835920929579. |
| 9 | Hagemann-Jensen M, Ziegenhain C, Chen P, Ramsköld D, Hendriks G-J, Larsson AJM, Faridani OR, Sandberg R. Single-cell RNA counting at allele and isoform resolution using Smart-seq3. Nature Biotechnology. 2020 May. [IF 45.1] |
| 10 | Hastings JF, Gonzalez Rajal A, Latham SL, Han JZ, McCloy RA, O'Donnell YE, Phimmachanh M, Murphy AD, Nagrial A, Daneshvar D, Chin V, Watkins DN, Burgess A, Croucher DR. Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma. Elife. 2020;9:e53367. Published 2020 Jun 9. [IF 7.1] |
| 11 | HCA Lung Network Powell J. Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and highlights inflammatory programs in putative target cells. Cell, 181, 1016-1035. [IF 36.2] doi: https://doi.org/10.1101/2020.04.19.049254 |
| 12 | Kott KA, Vernon ST, Hansen T, de Dreu M, Das SK, Powell J, Fazekas de St Groth B, Di Bartolo BA, McGuire HM, Figtree GA. Single-Cell Immune Profiling in Coronary Artery Disease: The Role of State-of-the-Art Immunophenotyping With Mass Cytometry in the Diagnosis of Atherosclerosis. J Am Heart Assoc. 2020 Dec 15;9(24):e017759. doi: 10.1161/JAHA.120.017759. Epub 2020 Nov 30. |
| 13 | Lee J, Shah M, Ballouz S, Crow M, Gillis J. CoCoCoNet: conserved and comparative co-expression across a diverse set of species. Nucleic Acids Res. 48(W1)W566–W57, 02 July 2020. [IF 11.5] |
| 14 | Lidgerwood GE, Senabouth A, Smith-Anttila CJA, Gnanasambandapillai V, Kaczorowski DC, Amann-Zalcenstein D, Fletcher EL, Naik SH, Hewitt AW, Powell JE, Pébay A. Transcriptomic Profiling of Human Pluripotent Stem Cell-derived Retinal Pigment Epithelium over Time. Genomics Proteomics Bioinformatics. 2020 Dec 8:S1672-0229(20)30135-2. doi: 10.1016/j.gpb.2020.08.002. Epub ahead of print. |
| 15 | Mereu E, Lafzi A, Moutinho C, Ziegenhain C, McCarthy DJ, Álvarez-Varela A, Batlle E, Sagar, Grün D, Lau JK, Boutet SC, Sanada C, Ooi A, Jones RC, Kaihara K, Brampton C, Talaga Y, Sasagawa Y, Tanaka K, Hayashi T, Braeuning C, Fischer C, Sauer S, Trefzer T, Conrad C, Adiconis X, Nguyen LT, Regev A, Levin JZ, Parekh S, Janjic A, Wange LE, Bagnoli JW, Enard W, Gut M, Sandberg R, Nikaido I, Gut I, Stegle O, Heyn H. Benchmarking single-cell RNA-sequencing protocols for cell atlas projects. Nat Biotechnol. 2020 Jun;38(6):747-755. doi: 10.1038/s41587-020-0469-4. Epub 2020 Apr 6. |
| 16 | Mereu, E., Lafzi, A., Moutinho, C. et al. Benchmarking single-cell RNA-sequencing protocols for cell atlas projects. Nat Biotechnol. 2020 April 6. https://doi.org/10.1038/s41587-020-0469-4. |
| 17 | Ogger PP, Albers GJ, Hewitt RJ, O'Sullivan BJ, Powell JE, Calamita E, Ghai P, Walker SA, McErlean P, Saunders P, Kingston S, Molyneaux PL, Halket JM, Gray R, Chambers DC, Maher TM, Lloyd CM, Byrne AJ. Itaconate controls the severity of pulmonary fibrosis. Sci Immunol. 2020 Oct 23;5(52):eabc1884. doi: 10.1126/sciimmunol.abc1884. |
| 18 | Pang CNI, Ballouz S, Weissberger D, Thibaut LM, Hamey JJ, Gillis J, Wilkins MR, Hart-Smith G. Analytical guidelines for co-fractionation mass spectrometry obtained through global profiling of gold standard Saccharomyces cerevisiae protein complexes. Mol Cell Proteomics. 2020 Aug 18:mcp.RA120.002154. doi: 10.1074/mcp.RA120.002154. |
| 19 | Payne, K., Li, W., Salomon, R. and Ma, C.S. OMIP‐063: 28‐Color Flow Cytometry Panel for Broad Human Immunophenotyping. Cytometry. 2020 April 16; doi:10.1002/cyto.a.24018. |
| 20 | Pineda SS, Chin YK, Undheim EAB, Senff S, Mobli M, Dauly C, Escoubas P, Nicholson GM, Kaas Q, Guo S, Herzig V, Mattick JS, King GF. Structural venomics reveals evolution of a complex venom by duplication and diversification of an ancient peptide-encoding gene. Proc Natl Acad Sci USA. 2020 May 26;117(21):11399-11408. Epub 2020 May 12. [IF 10.6] |
| 21 | Pinese M, Lacaze P, Rath EM, Stone A, Brion MJ, Ameur A, Nagpal S, Puttick C, Husson S, Degrave D, Cristina TN, Kahl VFS, Statham AL, Woods RL, McNeil JJ, Riaz M, Barr M, Nelson MR, Reid CM, Murray AM, Shah RC, Wolfe R, Atkins R, Fitzsimmons C, Cairns HM, Green MJ, Carr VJ, Cowley MJ, Pickett HA, James PA, Powell JE, Kaplan W, Gibson G, Gyllensten U, Cairns MJ, McNamara M, Dinger, ME & Thomas DM. The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly. Nat Commun. 2020 Jan 23;11(1):435. DOI: 10.1038/s41467-019-14079-0 |
| 22 | Senabouth A, Andersen S, Shi Q, Shi L, Jiang F, Zhang W, Wing K, Daniszewski M, Lukowski SW, Hung S, Nguyen Q, Fink L, Beckhouse A, Pébay A, Hewitt AW, Powell JE. Comparative performance of the BGI and Illumina sequencing technology for single-cell RNA-sequencing. Nucleic Acids Res. 2(2) June 2020. [IF 11.5] |
| 23 | Sinclair, KA, Yerkovich, ST, Hopkins, PM, Fieuw, AM, Ford, P, Powell, JE, O'Sullivan, B, Chambers, DC. The Autotaxin-Lysophosphatidic-Acid Pathway Mediates Mesenchymal Cell Recruitment and Fibrotic Contraction in Lung Transplant Fibrosis. The Journal of Heart and Lung Transplantation, 2020 Oct 21;10.005. doi: 10.1016/j.healun.2020.10.005 |
| 24 | Singh M, Jackson KJL, Wang JJ, Schofield P, Field MA, Koppstein D, Peters TJ, Burnett DL, Rizzetto S, Nevoltris D, Masle-Farquhar E, Faulks ML, Russell A, Gokal D, Hanioka A, Horikawa K, Colella AD, Chataway TK, Blackburn J, Mercer TR, Langley DB, Goodall DM, Jefferis R, Gangadharan Komala M, Kelleher AD, Suan D, Rischmueller M, Christ D, Brink R, Luciani F, Gordon TP, Goodnow CC, Reed JH. Lymphoma driver mutations in the pathogenic evolution of an iconic human autoantibody. Cell 2020; 180:878-894. DOI:https://doi.org/10.1016/j.cell.2020.01.029 |
| 25 | Tucker NR, Chaffin M, Bedi KC Jr, Papangeli I, Akkad AD, Arduini A, Hayat S, Eraslan G, Muus C, Bhattacharyya RP, Stegmann CM; Human Cell Atlas Lung Biological Network, Margulies KB, Ellinor PT; Human Cell Atlas Lung Biological Network Consortium Members. Myocyte-Specific Upregulation of ACE2 in Cardiovascular Disease: Implications for SARS-CoV-2-Mediated Myocarditis. Circulation. 2020 Aug 18;142(7):708-710. doi: 10.1161/CIRCULATIONAHA.120.047911. Epub 2020 Jun 22. |
| 26 | Wu SZ, Roden DL, Wang C, Holliday H, Harvey K, Cazet AS, Murphy KJ, Pereira B, Al-Eryani G, Bartonicek N, Hou R, Torpy JR, Junankar S, Chan CL, Lam CE, Hui MN, Gluch L, Beith J, Parker A, Robbins E, Segara D, Mak C, Cooper C, Warrier S, Forrest A, Powell J, O'Toole S, Cox TR, Timpson P, Lim E, Liu XS, Swarbrick A. Stromal cell diversity associated with immune evasion in human triple-negative breast cancer. EMBO J. 2020 Aug 13:e104063. doi: 10.15252/embj.2019104063. |
| 27 | Yabas, M.; Yazicioglu, Y. F.; Hoyne, G. F.; Goodnow, C. C.; Enders, A. Loss of hnRNPLL-dependent splicing of Ptprc has no impact on B-cell development, activation and terminal differentiation into antibody-secreting cells. IMMUNOLOGY AND CELL BIOLOGY 2020 DOI: https://doi.org/10.1111/imcb.12433 |
| 1 | Ahmed AT, MahmoudianDehkordi S, Bhattacharyya S, Arnold M, Liu D, Neavin D, et al. Acylcarnitine metabolomic profiles inform clinically-defined major depressive phenotypes. J Affect Disord. 2020;264(October 2019):90–7. DOI: 10.1016/j.jad.2019.11.122 |
| 2 | Alquicira-Hernandez J, Sathe A, Ji HP, Nguyen Q, Powell JE. scPred: accurate supervised method for cell-type classification from single-cell RNA-seq data. Genome Biol. 2019 Dec 12;20(1):264. DOI: 10.1186/s13059-019-1862-5 |
| 3 | Chambers DC, Carew AM, Lukowski SW, Powell JE. Transcriptomics and single-cell RNA-sequencing. Respirology. 2019 Jan;24(1):29-36. DOI: 10.1111/resp.13412 |
| 4 | Farbehi, N, Patrick, R, Dorison, A., Janbandhu, V, Xaymardan, M, Wystub-Lis, W, Ho, J, Nordon, R, Harvey, P. Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury. Elife, 2019 Mar 26;8. DOI: 10.7554/eLife.43882 |
| 5 | Hardwick SA, Bassett SD, Kaczorowski D, Blackburn J, Barton K, Bartonicek N, Carswell SL, Tilgner HU, Loy C, Halliday G, Mercer TR, Smith MA, Mattick JS. Targeted, High-Resolution RNA Sequencing of Non-coding Genomic Regions Associated With Neuropsychiatric Functions. Front Genet. 2019 Apr 12;10:309. DOI: 10.3389/fgene.2019.00309 |
| 6 | Kayagaki N, Lee BL, Stowe IB, Kornfeld OS, O'Rourke K, Mirrashidi KM, Haley B, Watanabe C, Roose-Girma M, Modrusan Z, Kummerfeld S, Reja R, Zhang Y, Cho V, Andrews TD, Morris LX, Goodnow CC, Bertram EM, Dixit VM. IRF2 transcriptionally induces GSDMD expression for pyroptosis. Sci Signal 2019; 12(582). doi: 10.1126/scisignal.aax4917 |
| 7 | Koay HF, Su S, Amann-Zalcenstein D, Daley SR, Comerford I, Miosge L, Whyte CE, Konstantinov IE, d'Udekem Y, Baldwin T, Hickey PF, Berzins SP, Mak JYW, Sontani Y, Roots CM, Sidwell T, Kallies A, Chen Z, Nüssing S, Kedzierska K, Mackay LK, McColl SR, Deenick EK, Fairlie DP, McCluskey J, Goodnow CC, Ritchie ME, Belz GT, Naik SH, Pellicci DG, Godfrey DI. A divergent transcriptional landscape underpins the development and functional branching of MAIT cells. Science Immunol. 2019;4(41). pii: eaay6039. doi: 10.1126/sciimmunol.aay6039. |
| 8 | Lau A, Avery DT, Jackson K, Lenthall H, Volpi S, Brigden H, Russell AJ, Bier J, Reed JH, Smart JM, Cole T, Choo S, Gray PE, Berglund LJ, Hsu P, Wong M, O'Sullivan M, Boztug K, Meyts I, Uzel G, Notarangelo LD, Brink R, Goodnow CC, Tangye SG, Deenick EK. Activated PI3Kdelta breaches multiple B cell tolerance checkpoints and causes autoantibody production. J Exp Med 2020; 217(2). doi: 10.1084/jem.20191336 |
| 9 | Leong TL, Gayevskiy V, Steinfort DP, De Massy MR, Gonzalez-Rajal A, Marini KD, Stone E, Chin V, Havryk A, Plit M, Irving LB. Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer. Oncogene. 2019 Mar;38(10):1661-75. DOI: 10.1038/s41388-018-0536-1 |
| 10 | Lingham G, Mackey DA, Lucas R, Yazar S. How does spending time outdoors protect against myopia? A review. British Journal of Ophthalmology. 2019 Nov 13. DOI: 10.1136/bjophthalmol-2019-314675 |
| 11 | Lukowski SW, Lo CY, Sharov AA, Nguyen Q, Fang L, Hung SS, Zhu L, Zhang T, Granert U, Nguyen T, Senabouth A, Jabbari JS, Welby E, Sowden JC, Waugh HS, Mackey A, Pollock G, Lamb TD, Wang PY, Hewitt AW, Gillies MC, Powell JE, et al. A single-cell transcriptome atlas of the adult human retina. EMBO J. 2019 Sep 16;38(18):e100811. DOI: 10.15252/embj.2018100811 |
| 12 | Lukowski SW, Patel J, Andersen SB, Sim SL, Wong HY, Tay J, Winkler I, Powell JE*, Khosrotehrani K. *Joint Senior. Single-Cell Transcriptional Profiling of Aortic Endothelium Identifies a Hierarchy from Endovascular Progenitors to Differentiated Cells. Cell Rep. 2019 May 28;27(9):2748-2758.e3. DOI: 10.1016/j.celrep.2019.04.102 |
| 13 | Moran I, Avery DT, Payne K, Lenthall H, Davies EG, Burns S, Ip W, Oleastro MM, Reisli I, Guner S, Keles S, Notarangelo L, Deenick EK, Goodnow CC, Zahra D, Brink R, Circa, Wong M, Tangye SG, Ma CS, Phan TG. B cell-intrinsic requirement for STK4 in humoral immunity in mice and human subjects. J Allergy Clin Immunol. 2019; 143(6):2302-5. doi: 10.1016/j.jaci.2019.02.010 |
| 14 | Neavin DR, Lee J-H, Liu D, Ye Z, Li H, Wang L, et al. Single Nucleotide Polymorphisms at a Distance from Aryl Hydrocarbon Receptor Binding Sites Influence AHR Ligand-Dependent Gene Expression. Drug Metab Dispos 2019 Sep;47(9):983-994. doi: 10.1124/dmd.119.087312. Epub 2019 Jul 10. DOI: 10.1124/dmd.119.087312 |
| 15 | O'Sullivan, B. & Powell, J. & Lukowski, S. & Tan, Maxine & Hopkins, P. & Chambers, D. (2019). Reconstruction of Transcriptional Programs of Monocyte to Macrophage Sequential Cell Fate Transition Using Single Cell RNA Sequencing in Sex Mis-Matched Lung Transplantation. The Journal of Heart and Lung Transplantation. 2019 April 38. S157. 10.1016 DOI: https://doi.org/10.1016/j.healun.2019.01.375 |
| 16 | Policheni A, Horikawa K, Milla L, Kofler J, Bouillet P, Belz GT, O'Reilly LA, Goodnow CC, Strasser A, Gray DH. CARD11 is dispensable for homeostatic responses and suppressive activity of peripherally induced FOXP3(+) regulatory T cells. Immunol Cell Biol. 2019; 97(8):740-52. doi: 10.1111/imcb.12268 |
| 17 | Qin S, Eugene AR, Liu D, Zhang L, Neavin D, Biernacka JM, et al. Dual Roles for the TSPYL Family in Mediating Serotonin Transport and the Metabolism of Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder. Clin Pharmacol Ther. 2020 Mar;107(3):662-670. doi: 10.1002/cpt.1692. Epub 2019 Nov 30. DOI: 10.1002/cpt.1692 |
| 18 | Salomon, R, Kaczorowski, D, Valdes-Mora, F, E. Nordon, R, Neild, A, Farbehi, N, Bartonic, N, Gallego-Ortega, D. Droplet-based single cell RNAseq tools: A practical guide. Lab Chip. 2019 May 14;19(10):1706-1727. DOI: 10.1039/c8lc01239c |
| 19 | Senabouth A, Lukowski SW, Hernandez JA, Andersen SB, Mei X, Nguyen QH, Powell JE. ascend: R package for analysis of single-cell RNA-seq data. Gigascience. 2019 Aug 1;8(8). DOI: 10.1093/gigascience/giz087 |
| 20 | Siggs OM, Russell A, Singh-Grewal D, Wong M, Chan P, Craig ME, O'Loughlin T, Stormon M, Goodnow CC. Preponderance of CTLA4 Variation Associated With Autosomal Dominant Immune Dysregulation in the MYPPPY Motif. Front Immunol 2019; 10:1544. doi: 10.3389/fimmu.2019.01544 |
| 21 | Singh M, Al-Eryani G, Carswell S, Ferguson JM, Blackburn J, Barton K, Roden D, Luciani F, Giang Phan T, Junankar S, Jackson K, Goodnow CC, Smith MA, Swarbrick A. High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes. Nat Commun 2019; 10:3120. doi: 10.1038/s41467-019-11049-4 |
| 22 | Skvortsova K, Masle-Farquhar E, Luu PL, Song JZ, Qu W, Zotenko E, Gould CM, Du Q, Peters TJ, Colino-Sanguino Y, Pidsley R, Nair SS, Khoury A, Smith GC, Miosge LA, Reed JH, Kench JG, Rubin MA, Horvath L, Bogdanovic O, Lim SM, Polo JM, Goodnow CC, Stirzaker C, Clark SJ. DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns. Cancer Cell. 2019; 35(2):297-314 e8. doi: 10.1016/j.ccell.2019.01.004. |
| 23 | Wang H, Zhang F, Zeng J, Wu Y, Kemper KE, Xue A, Zhang M, Powell JE, Goddard ME, Wray NR, Visscher PM, McRae AF, Yang J. Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. Sci Adv. 2019 Aug 14;5(8):eaaw3538. DOI: 10.1126/sciadv.aaw3538 |
| 24 | Wilson BE, Routy B, Nagrial A, Chin VT. The effect of antibiotics on clinical touches in immune-checkpoint blockade: a systematic review and meta-analysis of observational studies. Cancer Immune Immunotherapy. 2019 Dec 21 DOI: 10.1007/s00262-019-02453-2 |
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