Researcher

Associate Professor Alexander Swarbrick

Field of Research (FoR)

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Biography

Research Interests:
The large majority of cancers arise through sporadic genetic and epigenetic alterations during a person's life. By identifying these alterations, we will greatly improve our ability to predict and treat the emergence of lethal cancers. My lab focuses on adult breast and prostate cancers and the childhood disease neuroblastoma. 

We use single cell genomics and related techniques to uncover the genetic 'wiring' operating...view more

Research Interests:
The large majority of cancers arise through sporadic genetic and epigenetic alterations during a person's life. By identifying these alterations, we will greatly improve our ability to predict and treat the emergence of lethal cancers. My lab focuses on adult breast and prostate cancers and the childhood disease neuroblastoma. 

We use single cell genomics and related techniques to uncover the genetic 'wiring' operating within the microenvironment of cancers,  to identify new mechanisms of disease and therapeutic strategies. We are particularly interested in finding novel therapeutic opportunities in stromal-epithelial signaling and cancer immunology. We use preclinical models to test the efficacy of these new treatments, and with clinical collaborators move these into early phase clinical trials. 

My lab is a multi-disciplinary collaboration of cell biology, pathology, oncology, computation biology and genetics. Its a great place to learn, and good fun to boot.  

Broad Research Areas:
Cancer, Cell Biology and Gene Regulation, single cell genomics, cellular genomics, single cell RNA-Seq, animal models, translational research

Specific Research Keywords:
Metastasis, Cell Biology, Molecular Biology, Breast Cancer, prostate cancer, single cell genomics, transcriptomics


My Qualifications

BSc (Hons) PhD


My Awards

NHMRC Senior Research Fellowship

NSW Premier’s award for Outstanding Research Fellow, Cancer Institute NSW

NHMRC Career Development Fellowship II

CINSW Early Career Fellowship and NBCF Early Career Fellowship

Sydney University Medal for Excellence in Medical Research

NHMRC CJ Martin Fellowship


My Research Supervision


Supervision keywords


Areas of supervision

I am an engaged and accomplished mentor, having supervised more than a dozen students to successful completion. 

I am looking for students in these courses: ILP, Honours, Masters and PhD

I am interested in applicants with backgrounds in:

- Cell and molecular biology

- Immunology

- Cancer Medicine, especially medical Oncology and Pathology

- Bioinformatics and computational biology

- Anatomy


Currently supervising

5 postdoctoral fellows

4 PhD students

2 Honours Students

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Location

Garvan Institute of Medical Research
384 Victoria st
Darlinghurst, NSW 2010

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Contact

+61-2-9295-8366
+61-2-9295-8321