Select Publications

Journal articles

Abouelezz A; Stefen H; Segerstråle M; Micinski D; Minkeviciene R; Lahti L; Hardeman EC; Gunning PW; Hoogenraad CC; Taira T; Fath T; Hotulainen P, 2020, 'Tropomyosin Tpm3.1 Is Required to Maintain the Structure and Function of the Axon Initial Segment', iScience, vol. 23,

Tran C; Heng B; Teo JD; Humphrey SJ; Qi Y; Couttas TA; Stefen H; Brettle M; Fath T; Guillemin GJ; Don AS, 2020, 'Sphingosine 1-phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes', Journal of Neurochemistry, vol. 153, pp. 173 - 188,

Dobson-Stone C; Hallupp M; Shahheydari H; Ragagnin AMG; Chatterton Z; Carew-Jones F; Shepherd CE; Stefen H; Paric E; Fath T; Thompson EM; Blumbergs P; Short CL; Field CD; Panegyres PK; Hecker J; Nicholson G; Shaw AD; Fullerton JM; Luty AA; Schofield PR; Brooks WS; Rajan N; Bennett MF; Bahlo M; Landers JE; Piguet O; Hodges JR; Halliday GM; Topp SD; Smith BN; Shaw CE; McCann E; Fifita JA; Williams KL; Atkin JD; Blair IP; Kwok JB, 2020, 'CYLD is a causative gene for frontotemporal dementia - amyotrophic lateral sclerosis', Brain : a journal of neurology, vol. 143, pp. 783 - 799,

Sytnyk V; Fath T, 2020, 'Editorial: From Structure to Function - The Interplay Between Cell Adhesion Molecules and the Cytoskeleton', Frontiers in Cell and Developmental Biology, vol. 8, pp. 104,

Martin AD; Wojciechowski JP; Du EY; Rawal A; Stefen H; Au CG; Hou L; Cranfield CG; Fath T; Ittner LM; Thordarson P, 2020, 'Decoupling the effects of hydrophilic and hydrophobic moieties at the neuron-nanofibre interface', Chemical Science, vol. 11, pp. 1375 - 1382,

Lei M; Teo JD; Song H; McEwen HP; Yup Lee J; Couttas TA; Duncan T; Chesworth R; Bertz J; Przybyla M; Van Eersel J; Heng B; Guillemin GJ; Ittner LM; Fath T; Garner B; Ittner A; Karl T; Don AS, 2019, 'Sphingosine Kinase 2 Potentiates Amyloid Deposition but Protects against Hippocampal Volume Loss and Demyelination in a Mouse Model of Alzheimer's Disease', The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 39, pp. 9645 - 9659,

Brettle M; Stefen H; Djordjevic A; Fok SYY; Chan JW; van Hummel A; van der Hoven J; Przybyla M; Volkerling A; Ke YD; Delerue F; Ittner LM; Fath T, 2019, 'Developmental Expression of Mutant PFN1 in Motor Neurons Impacts Neuronal Growth and Motor Performance of Young and Adult Mice', Frontiers in Molecular Neuroscience, vol. 12,

Turner N; Lim XY; Toop HD; Osborne B; Brandon AE; Taylor EN; Fiveash CE; Govindaraju H; Teo JD; McEwen HP; Couttas TA; Butler SM; Das A; Kowalski GM; Bruce CR; Hoehn KL; Fath T; Schmitz-Peiffer C; Cooney GJ; Montgomery MK; Morris JC; Don AS, 2018, 'A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism', Nature Communications, vol. 9,

Stefen H; Hassanzadeh-Barforoushi A; Brettle M; Fok S; Suchowerska AK; Tedla N; Barber T; Warkiani ME; Fath T, 2018, 'A Novel Microfluidic Device-Based Neurite Outgrowth Inhibition Assay Reveals the Neurite Outgrowth-Promoting Activity of Tropomyosin Tpm3.1 in Hippocampal Neurons', Cellular and Molecular Neurobiology, vol. 38, pp. 1557 - 1563,

Gray KT; Stefen H; Ly TNA; Keller CJ; Colpan M; Wayman GA; Pate E; Fath T; Kostyukova AS, 2018, 'Tropomodulin’s Actin-Binding Abilities Are Required to Modulate Dendrite Development', Frontiers in Molecular Neuroscience, vol. 11,

Nguyen HL; Ruhoff AM; Fath T; Jones NM, 2018, 'Hypoxic postconditioning enhances functional recovery following endothelin-1 induced middle cerebral artery occlusion in conscious rats', Experimental Neurology, vol. 306, pp. 177 - 189,

Martin AD; Chua SW; Au CG; Stefen H; Przybyla M; Lin Y; Bertz J; Thordarson P; Fath T; Ke YD; Ittner LM, 2018, 'Peptide Nanofiber Substrates for Long-Term Culturing of Primary Neurons', ACS Applied Materials and Interfaces, vol. 10, pp. 25127 - 25134,

Stefen H; Suchowerska AK; Chen BJ; Brettle M; Kuschelewski J; Gunning PW; Janitz M; Fath T, 2018, 'Tropomyosin isoforms have specific effects on the transcriptome of undifferentiated and differentiated B35 neuroblastoma cells', FEBS Open Bio, vol. 8, pp. 570 - 583,

Fröhlich D; Suchowerska AK; Voss C; He R; Wolvetang E; Von Jonquieres G; Simons C; Fath T; Housley GD; Klugmann M, 2018, 'Expression pattern of the aspartyl-tRNA synthetase DARS in the human brain', Frontiers in Molecular Neuroscience, vol. 11,

Tonkin RS; Bowles C; Perera CJ; Keating BA; Makker PGS; Duffy SS; Lees JG; Tran C; Don AS; Fath T; Liu L; O'Carroll SJ; Nicholson LFB; Green CR; Gorrie C; Moalem-Taylor G, 2018, 'Attenuation of mechanical pain hypersensitivity by treatment with Peptide5, a connexin-43 mimetic peptide, involves inhibition of NLRP3 inflammasome in nerve-injured mice', Experimental Neurology, vol. 300, pp. 1 - 12,

Suchowerska AK; Fok S; Stefen H; Gunning PW; Hardeman EC; Power J; Fath T, 2017, 'Developmental profiling of tropomyosin expression in mouse brain reveals Tpm4.2 as the major post-synaptic tropomyosin in the mature brain', Frontiers in Cellular Neuroscience, vol. 11,

Bi M; Gladbach A; Van Eersel J; Ittner A; Przybyla M; Van Hummel A; Chua SW; Hoven JVD; Lee WS; Müller J; Parmar J; Jonquieres GV; Stefen H; Guccione E; Fath T; Housley GD; Klugmann M; Ke YD; Ittner LM, 2017, 'Tau exacerbates excitotoxic brain damage in an animal model of stroke', Nature Communications, vol. 8,

Patel S; Fok SYY; Stefen H; Tomanić T; Parić E; Herold R; Brettle M; Djordjevic A; Fath T, 2017, 'Functional characterisation of filamentous actin probe expression in neuronal cells', PLoS ONE, vol. 12,

Gormal R; Valmas N; Fath T; Meunier F, 2017, 'A role for tropomyosins in activity-dependent bulk endocytosis?', Molecular and Cellular Neuroscience, vol. 84, pp. 112 - 118,

Gray KT; Kostyukova AS; Fath T, 2017, 'Actin regulation by tropomodulin and tropomyosin in neuronal morphogenesis and function', Molecular and Cellular Neuroscience, vol. 84, pp. 48 - 57,

Fath T; Kostyukova AS; Foa L, 2017, 'Special issue on ‘Cytoskeleton-dependent regulation of neuronal network formation’', Molecular and Cellular Neuroscience, vol. 84, pp. 1 - 3,

Fröhlich D; Suchowerska AK; Spencer ZHT; von Jonquieres G; Klugmann CB; Bongers A; Delerue F; Stefen H; Ittner LM; Fath T; Housley GD; Klugmann M, 2017, 'In vivo characterization of the aspartyl-tRNA synthetase DARS: Homing in on the leukodystrophy HBSL', Neurobiology of Disease, vol. 97, pp. 24 - 35,

Brettle M; Patel S; Fath T, 2016, 'Tropomyosins in the healthy and diseased nervous system', Brain Research Bulletin, vol. 126, pp. 311 - 323,

Yang J-L; Polly P; Fath T; Jones NM; Power J, 2016, 'ISA model and integrative career development learning in year three science courses', Int J Science Math Tech Learning, vol. 23, pp. 33 - 46

Couttas TA; Kain N; Suchowerska AK; Quek LE; Turner N; Fath T; Garner B; Don AS, 2016, 'Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease', Neurobiology of Aging, vol. 43, pp. 89 - 100,

Gray KT; Suchowerska AK; Bland T; Colpan M; Wayman G; Fath T; Kostyukova AS, 2016, 'Tropomodulin isoforms utilize specific binding functions to modulate dendrite development', Cytoskeleton, vol. 73, pp. 316 - 328,

Knothe Tate ML; Fath T, 2016, 'The only constant is change: next generation medical devices for physical and mental health', Advanced healthcare materials, vol. 5, pp. 1840 - 1843,

Stefen H; Chaichim C; Power J; Fath T, 2016, 'Regulation of the Postsynaptic Compartment of Excitatory Synapses by the Actin Cytoskeleton in Health and Its Disruption in Disease', Neural Plasticity, vol. 2016,

An H; Brettle M; Lee T; Heng B; Lim CK; Guillemin GJ; Lord MS; Klotzsch E; Geczy CL; Bryant K; Fath T; Tedla N, 2016, 'Soluble LILRA3 promotes neurite outgrowth and synapses formation through a high-affinity interaction with Nogo 66', Journal of Cell Science, vol. 129, pp. 1198 - 1209,

Gray KT; Suchowerska AK; Bland T; Colpan M; Wayman G; Fath T; Kostyukova AS, 2016, 'Tropomodulin isoforms utilize specific binding functions to modulate dendrite development', Cytoskeleton,

Brettle M; Suchowerska AK; Chua SW; Ittner LM; Fath T, 2015, 'Amyotrophic lateral sclerosis-associated mutant profilin 1 increases dendritic arborisation and spine formation in primary hippocampal neurons', Neuroscience Letters, vol. 609, pp. 223 - 228,

Jalilian I; Heu C; Cheng H; Freittag H; Desouza M; Stehn JR; Bryce NS; Whan RM; Hardeman EC; Fath T; Schevzov G; Gunning PW, 2015, 'Cell elasticity is regulated by the tropomyosin isoform composition of the actin cytoskeleton', PLoS ONE, vol. 10,

Schevzov G; Kee AJ; Wang B; Sequeira VB; Hook J; Coombes JD; Lucas CA; Stehn JR; Musgrove EA; Cretu A; Assoian R; Fath T; Hanoch T; Seger R; Pleines I; Kile BT; Hardeman EC; Gunning PW, 2015, 'Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments', Molecular Biology of the Cell, vol. 26, pp. 2475 - 2490,

Sytnyk V; Fath T, 2015, 'Synapse Function in Dementia and Neurodegenerative Disorders', Australian Biochemist, vol. 46,

Suchowerska AK; Fath T, 2014, 'Cytoskeletal changes in diseases of the nervous system', Frontiers in Biology, vol. 9, pp. 5 - 17,

Curthoys NM; Freittag H; Connor A; Desouza M; Brettle M; Poljak A; Hall A; Hardeman E; Schevzov G; Gunning PW; Fath T, 2014, 'Tropomyosins induce neuritogenesis and determine neurite branching patterns in B35 neuroblastoma cells', Molecular and Cellular Neuroscience, vol. 58, pp. 11 - 21,

2014, '2014 ASCB/IFCB Meeting abstracts', Molecular Biology of the Cell, vol. 25, pp. 3987 - 3987,

Suchowerska A; Chen B; Mueller J; Ittner A; Hardeman E; Ittner L; Janitz M; Gunning P; Fath T, 2013, 'Increased levels of actin filaments containing the tropomyosin Tm5NM1 regulate excitotoxicity in the mouse', MOLECULAR BIOLOGY OF THE CELL, vol. 24,

Stehn JR; Haass NK; Bonello T; Desouza M; Kottyan G; Treutlein H; Zeng J; Nascimento PR; Sequeira VB; Butler TL; Allanson M; Fath T; Hill TA; McCluskey A; Schevzov G; Palmer S; Hardeman EC; Winlaw D; Reeve VE; Dixon I; Weninger W; Cripe TP; Gunning PW, 2013, 'A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells', Cancer research, vol. 73, pp. 5169 - 5182,

Fath T, 2013, 'Tropomodulins and tropomyosins - Organizers of cellular microcompartments', Biomolecular Concepts, vol. 4, pp. 89 - 101,

Dale RC; Merheb V; Pillai S; Wang D; Cantrill L; Murphy TK; Ben-Pazi H; Varadkar S; Aumann TD; Horne MK; Church AJ; Fath T; Brilot F, 2012, 'Antibodies to surface dopamine-2 receptor in autoimmune movement and psychiatric disorders', Brain, vol. 135, pp. 3453 - 3468,

Gerdes S; Osadtschy S; Rostami-Yazdi M; Buhles N; Weichenthal M; Mrowietz U, 2012, 'Leptin, adiponectin, visfatin and retinol-binding protein-4 - mediators of comorbidities in patients with psoriasis?', Experimental Dermatology, vol. 21, pp. 43 - 47,

2012, 'ADF Abstracts 2012', Experimental Dermatology, vol. 21, pp. e1 - e58,

Schevzov G; Curthoys NM; Gunning P; Fath T, 2012, 'Chapter Two – Functional Diversity of Actin Cytoskeleton in Neurons and its Regulation by Tropomyosin', International Review of Cell and Molecular Biology, vol. 298, pp. 33 - 94,

Hundelt M; Fath T; Selle K; Oesterwind K; Jordan J; Schultz C; Gotz J; Von engelhardt J; Monyer H; Lewejohann H; Lewejohann H; Bakota L; Brandt R, 2011, 'Altered phosphorylation but no neurodegeneration in a mouse model of tau hyperphosphorylation', Neurobiology of Aging, vol. 32, pp. 991 - 1006,

Schevzov G; Whittaker S; Fath T; Lin JJC; Gunning P, 2011, 'Everything you need to know about: Tropomyosin Isoforms and Reagents', BioArchitecture, vol. 1, pp. 135 - 164,

Hook J; Lemckert F; Schevzov G; Fath T; Gunning P, 2011, 'Functional identity of the gamma tropomyosin gene: Implications for embryonic development, reproduction and cell viability', BioArchitecture, vol. 1, pp. 49 - 59,

Gunning P; Fath T; Guven K, 2011, 'TPM3 and TPM4 gene products segregate to the postsynaptic region of central nervous system synapses', BioArchitecture, vol. 1, pp. 284 - 289,

Fath T; Fischer RS; Dehmelt L; Halpain S; Fowler V, 2011, 'Tropomodulins are negative regulators of neurite outgrowth', European Journal of Cell Biology, vol. 90, pp. 291 - 300,

2011, '2011 ASCB Annual Meeting abstracts', Molecular Biology of the Cell, vol. 22, pp. 4705 - 4705,

Back to profile page