Select Publications

Book Chapters

Chiew AL; Isbister GK, 2018, 'N-Acetylcysteine in the poisoned patient', in The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine, pp. 147 - 168, http://dx.doi.org/10.1007/978-981-10-5311-5_9

Journal articles

Chiew AL; Buckley NA, 2022, 'Comment on: "population pharmacokinetic analysis of acetaminophen overdose with immediate release, extended release and modified release formulations".', Clin Toxicol (Phila), pp. 1 - 2, http://dx.doi.org/10.1080/15563650.2022.2135519

Chiew AL; Raubenheimer JE; Berling I; Buckley NA; Becker T; Chan B; Brett J, 2022, 'Just ‘nanging’ around – harmful nitrous oxide use: a retrospective case series and review of Internet searches, social media posts and the coroner's database', Internal Medicine Journal, vol. 52, pp. 1724 - 1732, http://dx.doi.org/10.1111/imj.15391

Mirabella J; Ravi D; Chiew AL; Buckley NA; Chan BS, 2022, 'Prescribing trend of tapentadol in a Sydney local health district', British Journal of Clinical Pharmacology, vol. 88, pp. 3929 - 3935, http://dx.doi.org/10.1111/bcp.15448

Isoardi KZ; Chiew AL, 2022, 'Too much of a good thing: Bicarbonate toxicity following treatment of sodium channel blocker overdose', EMA - Emergency Medicine Australasia, vol. 34, pp. 639 - 641, http://dx.doi.org/10.1111/1742-6723.13995

Chan BS; Mirabella J; Allen K; Berling I; Chiew AL; Isoardi K; Brown J; Isbister G, 2022, 'Tapentadol exposures and poisonings in Australia', CLINICAL TOXICOLOGY, vol. 60, pp. 1063 - 1066, http://dx.doi.org/10.1080/15563650.2022.2074857

Pai K; Buckley NA; Isoardi KZ; Isbister GK; Becker T; Chiew AL; Cairns R; Brown JA; Chan BS, 2022, 'Optimising alkalinisation and its effect on QRS narrowing in tricyclic antidepressant poisoning', British Journal of Clinical Pharmacology, vol. 88, pp. 723 - 733, http://dx.doi.org/10.1111/bcp.15008

Chiew AL; Buckley NA, 2022, 'Authors' reply to comment on “the serotonin toxidrome: shortfalls of current diagnostic criteria for related syndromes”', Clinical Toxicology, pp. 1 - 2, http://dx.doi.org/10.1080/15563650.2022.2101472

McNab L; Varndell W; Vecellio E; Chiew AL, 2022, 'Clean the skin: Reducing blood culture contamination in the emergency department', EMA - Emergency Medicine Australasia, http://dx.doi.org/10.1111/1742-6723.14092

Chan BS; Isbister GK; Chiew A; Isoardi K; Buckley NA, 2022, 'Clinical experience with titrating doses of digoxin antibodies in acute digoxin poisoning. (ATOM-6)', Clinical Toxicology, vol. 60, pp. 433 - 439, http://dx.doi.org/10.1080/15563650.2021.1968422

Tan H; Stathakis P; Varghese B; Buckley NA; Chiew AL, 2022, 'Delayed Acetaminophen Absorption Resulting in Acute Liver Failure', Case Reports in Critical Care, vol. 2022, pp. 3672248, http://dx.doi.org/10.1155/2022/3672248

Li J; Chiew AL; Isbister GK; Duffull SB, 2022, 'Population pharmacokinetics of immediate-release and modified-release paracetamol and its major metabolites in a supratherapeutic dosing study', Clinical Toxicology, vol. 60, pp. 25 - 32, http://dx.doi.org/10.1080/15563650.2021.1928163

Chiew AL; Buckley NA, 2022, 'The serotonin toxidrome: shortfalls of current diagnostic criteria for related syndromes', Clinical Toxicology, vol. 60, pp. 143 - 158, http://dx.doi.org/10.1080/15563650.2021.1993242

Grealish M; Chiew AL; Varndell W; Depczynski B, 2021, 'The relationship between admission glucose and lactate with critical illness amongst adult patients presenting to the emergency department', Acta Diabetologica, vol. 58, pp. 1343 - 1349, http://dx.doi.org/10.1007/s00592-021-01725-7

Sun J; Stewart P; Chiew A; Becker T; Siu W; Varndell W; Chan BS, 2021, 'Association between shift work and cognitive performance on the Trail Making Test in emergency department health officers', EMA - Emergency Medicine Australasia, vol. 33, pp. 711 - 717, http://dx.doi.org/10.1111/1742-6723.13753

Chiew AL; Tran CTT; Mackenzie J, 2021, 'Effect of tourniquet time on whole blood point-of-care lactate concentration: A healthy human volunteer study', EMA - Emergency Medicine Australasia, vol. 33, pp. 647 - 654, http://dx.doi.org/10.1111/1742-6723.13697

Chiew AL; Buckley NA, 2021, 'Acetaminophen Poisoning', Critical Care Clinics, vol. 37, pp. 543 - 561, http://dx.doi.org/10.1016/j.ccc.2021.03.005

Li J; Chiew AL; Isbister GK; Duffull SB, 2021, 'Sulfate conjugation may be the key to hepatotoxicity in paracetamol overdose', British Journal of Clinical Pharmacology, vol. 87, pp. 2392 - 2396, http://dx.doi.org/10.1111/bcp.14642

Isbister GK; Chiew A, 2021, 'The changing face of paracetamol toxicity and new regimens for an old antidote acetylcysteine', British Journal of Clinical Pharmacology, vol. 87, pp. 715 - 716, http://dx.doi.org/10.1111/bcp.14495

Chiew AL; Buckley NA; Graudins A; Munir VL, 2021, 'Review article: Up (to) date for Australian Toxicology and Toxinology guidelines', EMA - Emergency Medicine Australasia, vol. 33, pp. 6 - 8, http://dx.doi.org/10.1111/1742-6723.13663

Huang J; Buckley NA; Isoardi KZ; Chiew AL; Isbister GK; Cairns R; Brown JA; Chan BS, 2021, 'Angiotensin axis antagonists increase the incidence of haemodynamic instability in dihydropyridine calcium channel blocker poisoning', Clinical Toxicology, vol. 59, pp. 464 - 471, http://dx.doi.org/10.1080/15563650.2020.1826504

Chan BS; Cheng S; Isoardi KZ; Chiew A; Siu W; Shulruf B; Vecellio E; Buckley NA, 2020, 'Effect of age on the severity of chronic lithium poisoning', Clinical Toxicology, vol. 58, pp. 1023 - 1027, http://dx.doi.org/10.1080/15563650.2020.1726376

Buckley NA; Cheng S; Isoardi K; Chiew AL; Siu W; Vecellio E; Chan BS, 2020, 'Haemodialysis for lithium poisoning: Translating EXTRIP recommendations into practical guidelines', British Journal of Clinical Pharmacology, vol. 86, pp. 999 - 1006, http://dx.doi.org/10.1111/bcp.14212

Jiang S; Madrasi K; Samant T; Lagishetty C; Vozmediano V; Chiew A; Abdel-Rahman SM; James LP; Schmidt S, 2020, 'Population Pharmacokinetic Modeling of Acetaminophen Protein Adducts in Adults and Children', Journal of Clinical Pharmacology, vol. 60, pp. 595 - 604, http://dx.doi.org/10.1002/jcph.1555

Khor NWM; Hepburn KS; Chiew AL; Somerville E; Micallef M; Lee ATK; Endre ZH, 2020, 'Chronic methyl bromide toxicity is ameliorated by haemodialysis', Internal Medicine Journal, vol. 50, pp. 370 - 373, http://dx.doi.org/10.1111/imj.14757

Chiew AL; James LP; Isbister GK; Pickering JW; McArdle K; Chan BSH; Buckley NA, 2020, 'Early acetaminophen-protein adducts predict hepatotoxicity following overdose (ATOM-5)', Journal of Hepatology, vol. 72, pp. 450 - 462, http://dx.doi.org/10.1016/j.jhep.2019.10.030

Chiew AL; Reith D; Pomerleau A; Wong A; Isoardi KZ; Soderstrom J; Buckley NA, 2020, 'Updated guidelines for the management of paracetamol poisoning in Australia and New Zealand', Medical Journal of Australia, vol. 212, pp. 175 - 183, http://dx.doi.org/10.5694/mja2.50428

Chiew AL; Domingo G; Buckley NA; Stathakis P; Ress K; Roberts DM, 2020, 'Hepatotoxicity in a child following an accidental overdose of liquid paracetamol.', Clin Toxicol (Phila), vol. 58, pp. 1063 - 1066, http://dx.doi.org/10.1080/15563650.2020.1722150

Scott-King JM; Tieu S; Chiew AL; Lui J; Kirby KA; Chan BS, 2019, 'Clinical decision rule for non-traumatic computed tomography of the brain', EMA - Emergency Medicine Australasia, vol. 31, pp. 974 - 981, http://dx.doi.org/10.1111/1742-6723.13292

Cheng S; Buckley NA; Siu W; Chiew AL; Vecellio E; Chan BS, 2019, 'Seasonal and temperature effect on serum lithium concentrations', AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY, vol. 54, pp. 282 - 287, http://dx.doi.org/10.1177/0004867419889160

Egan H; Isbister GK; Robinson J; Downes M; Chan BS; Vecellio E; Chiew AL, 2019, 'Retrospective evaluation of repeated supratherapeutic ingestion (RSTI) of paracetamol', Clinical Toxicology, vol. 57, pp. 703 - 711, http://dx.doi.org/10.1080/15563650.2018.1547829

Chan BS; Isbister GK; Page CB; Isoardi KZ; Chiew AL; Kirby KA; Buckley NA, 2019, 'Clinical outcomes from early use of digoxin-specific antibodies versus observation in chronic digoxin poisoning (ATOM-4)', Clinical Toxicology, vol. 57, pp. 638 - 643, http://dx.doi.org/10.1080/15563650.2018.1546010

McLenachan CJ; Chua O; Chan BSH; Vecellio E; Chiew AL, 2019, 'Comparison of Wells and YEARS clinical decision rules with D-dimer for low-risk pulmonary embolus patients', Internal Medicine Journal, vol. 49, pp. 739 - 744, http://dx.doi.org/10.1111/imj.14138

Chiew AL; Buckley NA, 2019, 'SNAP – A Large Step in the Move towards Personalised Dosing of Acetylcysteine', EClinicalMedicine, vol. 11, pp. 3 - 4, http://dx.doi.org/10.1016/j.eclinm.2019.04.012

Depczynski B; Lee ATK; Varndell W; Chiew AL, 2019, 'The Significance of an Increased Beta-Hydroxybutyrate at Presentation to the Emergency Department in Patients with Diabetes in the Absence of a Hyperglycemic Emergency', Journal of Diabetes Research, vol. 2019, http://dx.doi.org/10.1155/2019/7387128

Hepburn K; Khor N; Micallef M; Chiew A; Somerville E; Endre Z, 2019, 'SUN-332 DIALYSIS FOR TREATMENT OF CHRONIC METHYL BROMIDE TOXICITY: A CASE REPORT', Kidney International Reports, vol. 4, pp. S298 - S298, http://dx.doi.org/10.1016/j.ekir.2019.05.742

Chiew AL; Wright DFB; Dobos NM; McArdle K; Mostafa AA; Newth A; Roberts MS; Isbister GK, 2018, '‘Massive’ metformin overdose', British Journal of Clinical Pharmacology, vol. 84, pp. 2923 - 2927, http://dx.doi.org/10.1111/bcp.13582

Chiew AL; Wright DFB; Roberts MS; Isbister GK, 2018, 'Response to ‘Comment on ‘‘Massive’ metformin overdose’ by Chiew et al.’', British Journal of Clinical Pharmacology, vol. 84, pp. 2940 - 2941, http://dx.doi.org/10.1111/bcp.13747

Chan BSH; Chiew AL; Grainger S; Page CB; Gault A; Mostafa A; Roberts MS; Buckley NA; Isbister GK, 2018, 'Bromoxynil and 2-methyl-4-chlorophenoxyacetic acid (MCPA) poisoning could be a bad combination', Clinical Toxicology, vol. 56, pp. 861 - 863, http://dx.doi.org/10.1080/15563650.2018.1433299

Chiew AL; Isbister GK; Page CB; Kirby KA; Chan BSH; Buckley NA, 2018, 'Modified release paracetamol overdose: a prospective observational study (ATOM-3)', Clinical Toxicology, vol. 56, pp. 810 - 819, http://dx.doi.org/10.1080/15563650.2018.1439950

Chan BS; Mills N; Chiew A, 2018, 'Does physician education and factsheet impact on safe opioid use in emergency patients?', Canadian Journal of Addiction, vol. 9, pp. 26 - 33, http://dx.doi.org/10.1097/CXA.0000000000000019

Chiew AL; Page CB; Clancy D; Mostafa A; Roberts MS; Isbister GK, 2018, '2-Methyl-4-chlorophenoxyacetic acid (MCPA) and bromoxynil herbicide ingestion', Clinical Toxicology, vol. 56, pp. 377 - 380, http://dx.doi.org/10.1080/15563650.2017.1385790

Chan BS; Becker T; Chiew AL; Abdalla AM; Robertson TA; Liu X; Roberts MS; Buckley NA, 2018, 'Vasoplegic Shock Treated with Methylene Blue Complicated by Severe Serotonin Syndrome', Journal of Medical Toxicology, vol. 14, pp. 100 - 103, http://dx.doi.org/10.1007/s13181-017-0637-1

Chiew AL; Gluud C; Brok J; Buckley NA, 2018, 'Interventions for paracetamol (acetaminophen) overdose', Cochrane Database of Systematic Reviews, vol. 2018, http://dx.doi.org/10.1002/14651858.CD003328.pub3

Chiew AL; Isbister GK; Kirby KA; Page CB; Chan BSH; Buckley NA, 2017, 'Massive paracetamol overdose: an observational study of the effect of activated charcoal and increased acetylcysteine dose (ATOM-2)', Clinical Toxicology, vol. 55, pp. 1055 - 1065, http://dx.doi.org/10.1080/15563650.2017.1334915

Chan BS; Chiew A; Isbister GK; O’Leary M; Buckley NA, 2017, 'Authors’ responses to letter to the editor re: “Efficacy and effectiveness of anti-digoxin antibodies in chronic digoxin poisonings from the DORA study (ATOM-1)”', Clinical Toxicology, vol. 55, pp. 64, http://dx.doi.org/10.1080/15563650.2016.1214278

Corcoran G; Chan B; Chiew A, 2016, 'Use and knowledge of single dose activated charcoal: A survey of Australian doctors', EMA - Emergency Medicine Australasia, vol. 28, pp. 578 - 585, http://dx.doi.org/10.1111/1742-6723.12659

Chiew AL, 2016, 'New guidelines for the management of paracetamol poisoning in Australia and New Zealand (vol 203, pg 215, 2015)', MEDICAL JOURNAL OF AUSTRALIA, vol. 205, pp. 167 - 167, http://dx.doi.org/10.5694/mja2c15.00614

Chan BS; Isbister GK; O’Leary M; Chiew A; Buckley NA, 2016, 'Efficacy and effectiveness of anti-digoxin antibodies in chronic digoxin poisonings from the DORA study (ATOM-1)', Clinical Toxicology, vol. 54, pp. 488 - 494, http://dx.doi.org/10.1080/15563650.2016.1175620

Chiew A; Raos MP; Isbister GK, 2016, 'Sub-mammary injection of ropivacaine resulting in severe toxicity with seizures', EMA - Emergency Medicine Australasia, vol. 28, pp. 246 - 247, http://dx.doi.org/10.1111/1742-6723.12539


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