Select Publications

Book Chapters

Chiew AL; Isbister GK, 2018, 'N-Acetylcysteine in the poisoned patient', in The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine, pp. 147 - 168, http://dx.doi.org/10.1007/978-981-10-5311-5_9

Journal articles

Sun J; Stewart P; Chiew A; Becker T; Siu W; Varndell W; Chan BS, 2021, 'Association between shift work and cognitive performance on the Trail Making Test in emergency department health officers', EMA - Emergency Medicine Australasia, vol. 33, pp. 711 - 717, http://dx.doi.org/10.1111/1742-6723.13753

Chiew AL; Buckley NA, 2021, 'Acetaminophen Poisoning', Critical Care Clinics, vol. 37, pp. 543 - 561, http://dx.doi.org/10.1016/j.ccc.2021.03.005

Li J; Chiew AL; Isbister GK; Duffull SB, 2021, 'Sulfate conjugation may be the key to hepatotoxicity in paracetamol overdose', British Journal of Clinical Pharmacology, vol. 87, pp. 2392 - 2396, http://dx.doi.org/10.1111/bcp.14642

Isbister GK; Chiew A, 2021, 'The changing face of paracetamol toxicity and new regimens for an old antidote acetylcysteine', British Journal of Clinical Pharmacology, vol. 87, pp. 715 - 716, http://dx.doi.org/10.1111/bcp.14495

Chiew AL; Buckley NA; Graudins A; Munir VL, 2021, 'Review article: Up (to) date for Australian Toxicology and Toxinology guidelines', EMA - Emergency Medicine Australasia, vol. 33, pp. 6 - 8, http://dx.doi.org/10.1111/1742-6723.13663

Huang J; Buckley NA; Isoardi KZ; Chiew AL; Isbister GK; Cairns R; Brown JA; Chan BS, 2021, 'Angiotensin axis antagonists increase the incidence of haemodynamic instability in dihydropyridine calcium channel blocker poisoning', Clinical Toxicology, vol. 59, pp. 464 - 471, http://dx.doi.org/10.1080/15563650.2020.1826504

Chiew AL; Tran CTT; Mackenzie J, 2021, 'Effect of tourniquet time on whole blood point-of-care lactate concentration: A healthy human volunteer study', EMA - Emergency Medicine Australasia, http://dx.doi.org/10.1111/1742-6723.13697

Li J; Chiew AL; Isbister GK; Duffull SB, 2021, 'Population pharmacokinetics of immediate-release and modified-release paracetamol and its major metabolites in a supratherapeutic dosing study', Clinical Toxicology, http://dx.doi.org/10.1080/15563650.2021.1928163

Grealish M; Chiew AL; Varndell W; Depczynski B, 2021, 'The relationship between admission glucose and lactate with critical illness amongst adult patients presenting to the emergency department', Acta Diabetologica, http://dx.doi.org/10.1007/s00592-021-01725-7

Chan BS; Cheng S; Isoardi KZ; Chiew A; Siu W; Shulruf B; Vecellio E; Buckley NA, 2020, 'Effect of age on the severity of chronic lithium poisoning', Clinical Toxicology, vol. 58, pp. 1023 - 1027, http://dx.doi.org/10.1080/15563650.2020.1726376

Buckley NA; Cheng S; Isoardi K; Chiew AL; Siu W; Vecellio E; Chan BS, 2020, 'Haemodialysis for lithium poisoning: Translating EXTRIP recommendations into practical guidelines', British Journal of Clinical Pharmacology, vol. 86, pp. 999 - 1006, http://dx.doi.org/10.1111/bcp.14212

Khor NWM; Hepburn KS; Chiew AL; Somerville E; Micallef M; Lee ATK; Endre ZH, 2020, 'Chronic methyl bromide toxicity is ameliorated by haemodialysis', Internal Medicine Journal, vol. 50, pp. 370 - 373, http://dx.doi.org/10.1111/imj.14757

Chiew AL; James LP; Isbister GK; Pickering JW; McArdle K; Chan BSH; Buckley NA, 2020, 'Early acetaminophen-protein adducts predict hepatotoxicity following overdose (ATOM-5)', Journal of Hepatology, vol. 72, pp. 450 - 462, http://dx.doi.org/10.1016/j.jhep.2019.10.030

Chiew AL; Reith D; Pomerleau A; Wong A; Isoardi KZ; Soderstrom J; Buckley NA, 2020, 'Updated guidelines for the management of paracetamol poisoning in Australia and New Zealand', Medical Journal of Australia, vol. 212, pp. 175 - 183, http://dx.doi.org/10.5694/mja2.50428

Chiew AL; Domingo G; Buckley NA; Stathakis P; Ress K; Roberts DM, 2020, 'Hepatotoxicity in a child following an accidental overdose of liquid paracetamol.', Clin Toxicol (Phila), vol. 58, pp. 1063 - 1066, http://dx.doi.org/10.1080/15563650.2020.1722150

Scott-King JM; Tieu S; Chiew AL; Lui J; Kirby KA; Chan BS, 2019, 'Clinical decision rule for non-traumatic computed tomography of the brain', EMA - Emergency Medicine Australasia, vol. 31, pp. 974 - 981, http://dx.doi.org/10.1111/1742-6723.13292

Cheng S; Buckley NA; Siu W; Chiew AL; Vecellio E; Chan BS, 2019, 'Seasonal and temperature effect on serum lithium concentrations', AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY, vol. 54, pp. 282 - 287, http://dx.doi.org/10.1177/0004867419889160

Egan H; Isbister GK; Robinson J; Downes M; Chan BS; Vecellio E; Chiew AL, 2019, 'Retrospective evaluation of repeated supratherapeutic ingestion (RSTI) of paracetamol', Clinical Toxicology, vol. 57, pp. 703 - 711, http://dx.doi.org/10.1080/15563650.2018.1547829

Chan BS; Isbister GK; Page CB; Isoardi KZ; Chiew AL; Kirby KA; Buckley NA, 2019, 'Clinical outcomes from early use of digoxin-specific antibodies versus observation in chronic digoxin poisoning (ATOM-4)', Clinical Toxicology, vol. 57, pp. 638 - 643, http://dx.doi.org/10.1080/15563650.2018.1546010

McLenachan CJ; Chua O; Chan BSH; Vecellio E; Chiew AL, 2019, 'Comparison of Wells and YEARS clinical decision rules with D-dimer for low-risk pulmonary embolus patients', Internal Medicine Journal, vol. 49, pp. 739 - 744, http://dx.doi.org/10.1111/imj.14138

Chiew AL; Buckley NA, 2019, 'SNAP – A Large Step in the Move towards Personalised Dosing of Acetylcysteine', EClinicalMedicine, vol. 11, pp. 3 - 4, http://dx.doi.org/10.1016/j.eclinm.2019.04.012

Jiang S; Madrasi K; Samant T; Lagishetty C; Vozmediano V; Chiew A; Abdel-Rahman SM; James LP; Schmidt S, 2019, 'Population Pharmacokinetic Modeling of Acetaminophen Protein Adducts in Adults and Children', Journal of Clinical Pharmacology, http://dx.doi.org/10.1002/jcph.1555

Depczynski B; Lee ATK; Varndell W; Chiew AL, 2019, 'The Significance of an Increased Beta-Hydroxybutyrate at Presentation to the Emergency Department in Patients with Diabetes in the Absence of a Hyperglycemic Emergency', Journal of Diabetes Research, vol. 2019, http://dx.doi.org/10.1155/2019/7387128

Hepburn K; Khor N; Micallef M; Chiew A; Somerville E; Endre Z, 2019, 'SUN-332 DIALYSIS FOR TREATMENT OF CHRONIC METHYL BROMIDE TOXICITY: A CASE REPORT', Kidney International Reports, vol. 4, pp. S298 - S298, http://dx.doi.org/10.1016/j.ekir.2019.05.742

Chiew AL; Wright DFB; Dobos NM; McArdle K; Mostafa AA; Newth A; Roberts MS; Isbister GK, 2018, '‘Massive’ metformin overdose', British Journal of Clinical Pharmacology, vol. 84, pp. 2923 - 2927, http://dx.doi.org/10.1111/bcp.13582

Chiew AL; Wright DFB; Roberts MS; Isbister GK, 2018, 'Response to ‘Comment on ‘‘Massive’ metformin overdose’ by Chiew et al.’', British Journal of Clinical Pharmacology, vol. 84, pp. 2940 - 2941, http://dx.doi.org/10.1111/bcp.13747

Chan BSH; Chiew AL; Grainger S; Page CB; Gault A; Mostafa A; Roberts MS; Buckley NA; Isbister GK, 2018, 'Bromoxynil and 2-methyl-4-chlorophenoxyacetic acid (MCPA) poisoning could be a bad combination', Clinical Toxicology, vol. 56, pp. 861 - 863, http://dx.doi.org/10.1080/15563650.2018.1433299

Chiew AL; Isbister GK; Page CB; Kirby KA; Chan BSH; Buckley NA, 2018, 'Modified release paracetamol overdose: a prospective observational study (ATOM-3)', Clinical Toxicology, vol. 56, pp. 810 - 819, http://dx.doi.org/10.1080/15563650.2018.1439950

Chan BS; Mills N; Chiew A, 2018, 'Does physician education and factsheet impact on safe opioid use in emergency patients?', Canadian Journal of Addiction, vol. 9, pp. 26 - 33, http://dx.doi.org/10.1097/CXA.0000000000000019

Chiew AL; Page CB; Clancy D; Mostafa A; Roberts MS; Isbister GK, 2018, '2-Methyl-4-chlorophenoxyacetic acid (MCPA) and bromoxynil herbicide ingestion', Clinical Toxicology, vol. 56, pp. 377 - 380, http://dx.doi.org/10.1080/15563650.2017.1385790

Chan BS; Becker T; Chiew AL; Abdalla AM; Robertson TA; Liu X; Roberts MS; Buckley NA, 2018, 'Vasoplegic Shock Treated with Methylene Blue Complicated by Severe Serotonin Syndrome', Journal of Medical Toxicology, vol. 14, pp. 100 - 103, http://dx.doi.org/10.1007/s13181-017-0637-1

Chiew AL; Gluud C; Brok J; Buckley NA, 2018, 'Interventions for paracetamol (acetaminophen) overdose', Cochrane Database of Systematic Reviews, vol. 2018, http://dx.doi.org/10.1002/14651858.CD003328.pub3

Chiew AL; Isbister GK; Kirby KA; Page CB; Chan BSH; Buckley NA, 2017, 'Massive paracetamol overdose: an observational study of the effect of activated charcoal and increased acetylcysteine dose (ATOM-2)', Clinical Toxicology, vol. 55, pp. 1055 - 1065, http://dx.doi.org/10.1080/15563650.2017.1334915

Chan BS; Chiew A; Isbister GK; O’Leary M; Buckley NA, 2017, 'Authors’ responses to letter to the editor re: “Efficacy and effectiveness of anti-digoxin antibodies in chronic digoxin poisonings from the DORA study (ATOM-1)”', Clinical Toxicology, vol. 55, pp. 64, http://dx.doi.org/10.1080/15563650.2016.1214278

Corcoran G; Chan B; Chiew A, 2016, 'Use and knowledge of single dose activated charcoal: A survey of Australian doctors', EMA - Emergency Medicine Australasia, vol. 28, pp. 578 - 585, http://dx.doi.org/10.1111/1742-6723.12659

Chiew AL, 2016, 'New guidelines for the management of paracetamol poisoning in Australia and New Zealand (vol 203, pg 215, 2015)', MEDICAL JOURNAL OF AUSTRALIA, vol. 205, pp. 167 - 167, http://dx.doi.org/10.5694/mja2c15.00614

Chan BS; Isbister GK; O’Leary M; Chiew A; Buckley NA, 2016, 'Efficacy and effectiveness of anti-digoxin antibodies in chronic digoxin poisonings from the DORA study (ATOM-1)', Clinical Toxicology, vol. 54, pp. 488 - 494, http://dx.doi.org/10.1080/15563650.2016.1175620

Chiew A; Raos MP; Isbister GK, 2016, 'Sub-mammary injection of ropivacaine resulting in severe toxicity with seizures', EMA - Emergency Medicine Australasia, vol. 28, pp. 246 - 247, http://dx.doi.org/10.1111/1742-6723.12539

Chiew AL; Isbister GK; Duffull SB; Buckley NA, 2016, 'Evidence for the changing regimens of acetylcysteine', British Journal of Clinical Pharmacology, vol. 81, pp. 471 - 481, http://dx.doi.org/10.1111/bcp.12789

Isbister GK; Sellors KV; Beckmann U; Chiew AL; Downes MA; Berling I, 2015, 'Catecholamine-induced cardiomyopathy resulting from life-threatening funnel-web spider envenoming', Medical Journal of Australia, vol. 203, pp. 302 - 304.e1, http://dx.doi.org/10.5694/mja15.00279

Buckley NA; Chiew AL, 2015, 'Re: External validation of the paracetamol-aminotransferase multiplication product to predict hepatotoxicity from paracetamol overdose', Clinical toxicology (Philadelphia, Pa.), vol. 53, pp. 1152 - 1153, http://dx.doi.org/10.3109/15563650.2015.1096367

Chiew AL; Fountain JS; Graudins A; Isbister GK; Reith D; Buckley NA, 2015, 'Summary statement: New guidelines for the management of paracetamol poisoning in Australia and New Zealand', Medical Journal of Australia, vol. 203, pp. 215 - 218, http://dx.doi.org/10.5694/mja15.00614

Chan BSH; Sellors K; Chiew AL; Buckley NA, 2015, 'Use of multi-dose activated charcoal in phenytoin toxicity secondary to genetic polymorphism', Clinical Toxicology, vol. 53, pp. 131 - 133, http://dx.doi.org/10.3109/15563650.2014.998338

Chiew AL; Buckley NA, 2014, 'Carbon monoxide poisoning in the 21st century', Critical Care, vol. 18, http://dx.doi.org/10.1186/cc13846

Chiew AL; Isbister GK, 2014, 'A coagulopathic dilemma: Snakes or genes', The Lancet, vol. 383, pp. 2184, http://dx.doi.org/10.1016/S0140-6736(14)60690-5

Chiew AL; Khamoudes D; Chan BSH, 2014, 'Use of continuous veno-venous haemodiafiltration therapy in dabigatran overdose', Clinical Toxicology, vol. 52, pp. 283 - 287, http://dx.doi.org/10.3109/15563650.2014.900179

James LP; Chiew A; Abdel-Rahman SM; Letzig L; Graudins A; Day P; Roberts D, 2013, 'Acetaminophen protein adduct formation following low-dose acetaminophen exposure: Comparison of immediate-release vs extended-release formulations', European Journal of Clinical Pharmacology, vol. 69, pp. 851 - 857, http://dx.doi.org/10.1007/s00228-012-1410-7

Bailey AR; Sathianathan VJ; Chiew AL; Paterson AD; Chan BSH; Arora S, 2011, 'Comparison of intermittent haemodialysis, prolonged intermittent renal replacement therapy and continuous renal replacement haemofiltration for lithium toxicity: A case report', Critical Care and Resuscitation, vol. 13, pp. 120 - 122

Chiew A; Day P; Salonikas C; Naidoo D; Graudins A; Thomas R, 2010, 'The comparative pharmacokinetics of modified-release and immediate-release paracetamol in a simulated overdose model', EMA - Emergency Medicine Australasia, vol. 22, pp. 548 - 555, http://dx.doi.org/10.1111/j.1742-6723.2010.01354.x


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