Researcher

Dr Arcadi Cipponi

Fields of Research (FoR)

Cancer Genetics, Molecular Evolution

Biography

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Dr Arcadi Cipponi received his degree in Molecular Biology at the University of Milan, Italy. He obtained his PhD in Molecular and Cellular Pathology at the University of Parma, Italy.

In 2006 he moved to the Ludwing Institute of Cancer Research in Brussels where he worked on fundamental aspects of anti-tumor immune response in human melanoma.

 In 2011 he joined the group of Prof. David Thomas at the Peter MacCallum Cancer Centre in Melbourne to study the mechanisms driving adaptive mutagenesis of human cancer cells in response to pharmacologic pressures.

 He is currently Senior Research Officer in the Genomic Cancer Medicine Laboratory at the Kinghorn Cancer Centre in Sydney directed by Prof. David Thomas.

 Dr Cipponi’s interests include:

  • The development of in vitro models to define cancer risks associated with germline mutations in tumour suppressor genes
  • The spatial resolution of transcriptional landscapes in human cancer samples
  • The ex-vivo functional and transcriptional profiling of DNA repair defects in primary human cells

 


My Grants

2020-2021

Tour de Cure Pioneering Research Grant

 

2015-2018

NHMRC research grant

 

2013-2014                  

Foundation Grant, Peter MacCallum Cancer Institute, Melbourne Australia.

 

2006-2010                 

Belgian National Founds for Scientific Research (FNRS)

                                              


My Qualifications

2008 - Ph.D in Cellular and Molecular Pathology, University of Parma, Italy.

1998 - Degree in Biological Sciences, University of Milan, Italy.


My Research Activities

One of the main interests of the laboratory is to shed light on the hard-wired genetic and molecular mechanisms that are at the basis of the forces promoting adaptive strategies of human cancer cells in response to pharmacological and physiological stresses.

Additional projects are focused on:

  1. Exploiting pharmacologically-induced synthetic lethal vulnerabilities to enhance therapeutic responses in cancer
  2. the development of a new methodology to spatially resolve transcriptional landscapes in human cancer samples
  3. ex vivo functional and transcriptional profiling of DNA repair defects in primary human cells

 

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Location

The Kinghorn Cancer Centre
370 Victoria Street, Darlinghurst, NSW 2010, Australia

Map reference (Google map)

Contact

02 9355 5756

Publications

by Dr Arcadi Cipponi

ORCID as entered in ROS