Fields of Research (FoR)Cancer Genetics, Molecular Evolution
In 2006 he moved to the Ludwing Institute of Cancer Research in Brussels where he worked on fundamental aspects of anti-tumor immune response in human melanoma.
- The development of in vitro models to define cancer risks associated with germline mutations in tumour suppressor genes
- The spatial resolution of transcriptional landscapes in human cancer samples
- The ex-vivo functional and transcriptional profiling of DNA repair defects in primary human cells
Tour de Cure Pioneering Research Grant
NHMRC research grant
Foundation Grant, Peter MacCallum Cancer Institute, Melbourne Australia.
Belgian National Founds for Scientific Research (FNRS)
2008 - Ph.D in Cellular and Molecular Pathology, University of Parma, Italy.
1998 - Degree in Biological Sciences, University of Milan, Italy.
My Research Activities
One of the main interests of the laboratory is to shed light on the hard-wired genetic and molecular mechanisms that are at the basis of the forces promoting adaptive strategies of human cancer cells in response to pharmacological and physiological stresses.
Additional projects are focused on:
- Exploiting pharmacologically-induced synthetic lethal vulnerabilities to enhance therapeutic responses in cancer
- the development of a new methodology to spatially resolve transcriptional landscapes in human cancer samples
- ex vivo functional and transcriptional profiling of DNA repair defects in primary human cells