Select Publications

Journal articles

San Juan BP; Garcia-Leon MJ; Rangel L; Goetz JG; Chaffer CL, 2019, 'The complexities of metastasis', Cancers, vol. 11, http://dx.doi.org/10.3390/cancers11101575

Chaffer CL; Goetz JG, 2018, 'CD44 Orchestrates Metastatic Teamwork', Developmental Cell, vol. 47, pp. 691 - 693, http://dx.doi.org/10.1016/j.devcel.2018.11.038

Castaño Z; San Juan BP; Spiegel A; Pant A; DeCristo MJ; Laszewski T; Ubellacker JM; Janssen SR; Dongre A; Reinhardt F; Henderson A; del Rio AG; Gifford AM; Herbert ZT; Hutchinson JN; Weinberg RA; Chaffer CL; McAllister SS, 2018, 'IL-1β inflammatory response driven by primary breast cancer prevents metastasis-initiating cell colonization', Nature Cell Biology, vol. 20, pp. 1084 - 1097, http://dx.doi.org/10.1038/s41556-018-0173-5

Li J; Choi PS; Chaffer CL; Labella K; Hwang JH; Giacomelli AO; Kim JW; Ilic N; Doench JG; Ly SH; Dai C; Hagel K; Hong AL; Gjoerup O; Goel S; Ge JY; Root DE; Zhao JJ; Brooks AN; Weinberg RA; Hahn WC, 2018, 'An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer', eLife, vol. 7, http://dx.doi.org/10.7554/eLife.37184

van Dijk D; Sharma R; Nainys J; Yim K; Kathail P; Carr AJ; Burdziak C; Moon KR; Chaffer CL; Pattabiraman D; Bierie B; Mazutis L; Wolf G; Krishnaswamy S; Pe'er D, 2018, 'Recovering Gene Interactions from Single-Cell Data Using Data Diffusion', Cell, vol. 174, pp. 716 - 729.e27, http://dx.doi.org/10.1016/j.cell.2018.05.061

Bierie B; Pierce SE; Kroeger C; Stover DG; Pattabiraman DR; Thiru P; Donaher JL; Reinhardt F; Chaffer CL; Keckesova Z; Weinberg RA, 2017, 'Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells', Proceedings of the National Academy of Sciences of the United States of America, vol. 114, pp. E2337 - E2346, http://dx.doi.org/10.1073/pnas.1618298114

Chaffer CL; San Juan BP; Lim E; Weinberg RA, 2016, 'EMT, cell plasticity and metastasis', Cancer and Metastasis Reviews, vol. 35, pp. 645 - 654, http://dx.doi.org/10.1007/s10555-016-9648-7

Katajisto P; Döhla J; Chaffer CL; Pentinmikko N; Marjanovic N; Iqbal S; Zoncu R; Chen W; Weinberg RA; Sabatini DM, 2015, 'Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness', Science, vol. 348, pp. 340 - 343, http://dx.doi.org/10.1126/science.1260384

Chaffer CL; Weinberg RA, 2015, 'How does multistep tumorigenesis really proceed?', Cancer Discovery, vol. 5, pp. 22 - 24, http://dx.doi.org/10.1158/2159-8290.CD-14-0788

Marjanovic ND; Weinberg RA; Chaffer CL, 2013, 'Poised with purpose: Cell plasticity enhances tumorigenicity', Cell Cycle, vol. 12, pp. 2713 - 2714, http://dx.doi.org/10.4161/cc.26075

Chaffer CL; Marjanovic ND; Lee T; Bell G; Kleer CG; Reinhardt F; D'Alessio AC; Young RA; Weinberg RA, 2013, 'XPoised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity', Cell, vol. 154, pp. 61, http://dx.doi.org/10.1016/j.cell.2013.06.005

Marjanovic ND; Weinberg RA; Chaffer CL, 2013, 'Cell plasticity and heterogeneity in cancer', Clinical Chemistry, vol. 59, pp. 168 - 179, http://dx.doi.org/10.1373/clinchem.2012.184655

Scheel C; Eaton EN; Li SHJ; Chaffer CL; Reinhardt F; Kah KJ; Bell G; Guo W; Rubin J; Richardson AL; Weinberg RA, 2011, 'Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast', Cell, vol. 145, pp. 926 - 940, http://dx.doi.org/10.1016/j.cell.2011.04.029

Chaffer CL; Brueckmann I; Scheel C; Kaestli AJ; Wiggins PA; Rodrigues LO; Brooks M; Reinhardt F; Suc Y; Polyak K; Arendt LM; Kuperwasser C; Bierie B; Weinberg RA, 2011, 'Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state', Proceedings of the National Academy of Sciences of the United States of America, vol. 108, pp. 7950 - 7955, http://dx.doi.org/10.1073/pnas.1102454108

Chaffer CL; Weinberg RA, 2011, 'A perspective on cancer cell metastasis', Science, vol. 331, pp. 1559 - 1564, http://dx.doi.org/10.1126/science.1203543

Chaffer CL; Weinberg RA, 2010, 'Cancer cell of origin: Spotlight on luminal progenitors', Cell Stem Cell, vol. 7, pp. 271 - 272, http://dx.doi.org/10.1016/j.stem.2010.08.008

Tilkorn DJ; Lokmic Z; Chaffer CL; Mitchell GM; Morrison WA; Thompson EW, 2010, 'Disparate companions: Tissue engineering meets cancer research', Cells Tissues Organs, vol. 192, pp. 141 - 157, http://dx.doi.org/10.1159/000308892

Gupta PB; Chaffer CL; Weinberg RA, 2009, 'Cancer stem cells: Mirage or reality?', Nature Medicine, vol. 15, pp. 1010 - 1012, http://dx.doi.org/10.1038/nm0909-1010

Chaffer CL; Dopheide B; Savagner P; Thompson EW; Williams ED, 2007, 'Aberrant fibroblast growth factor receptor signaling in bladder and other cancers', Differentiation, vol. 75, pp. 831 - 842, http://dx.doi.org/10.1111/j.1432-0436.2007.00210.x

Chaffer CL; Brennan JP; Slavin JL; Blick T; Thompson EW; Williams ED, 2006, 'Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: Role of fibroblast growth factor receptor-2', Cancer Research, vol. 66, pp. 11271 - 11278, http://dx.doi.org/10.1158/0008-5472.CAN-06-2044

Chaffer CL; Thomas DM; Thompson EW; Williams ED, 2006, 'PPARγ-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma', BMC Cancer, vol. 6, http://dx.doi.org/10.1186/1471-2407-6-53

Chaffer CL; Dopheide B; McCulloch DR; Lee AB; Moseley JM; Thompson EW; Williams ED, 2005, 'Upregulated MT1-MMP/TIMP-2 axis in the TSU-Pr1-B1/B2 model of metastatic progression in transitional cell carcinoma of the bladder', Clinical and Experimental Metastasis, vol. 22, pp. 115 - 125, http://dx.doi.org/10.1007/s10585-005-5141-3

Chaffer CL; Morris MJ, 2002, 'The Feeding Response to Melanin-Concentrating Hormone Is Attenuated by Antagonism of the NPY Y1-Receptor in the Rat', Endocrinology, vol. 143, pp. 191 - 197, http://dx.doi.org/10.1210/en.143.1.191

Conference Papers

Castano Z; Chaffer CL; Spiegel A; Pant A; Richardson AL; Reinhardt F; Marsh T; Janssen S; Gifford AM; Weinberg RA; McAllister SS, 2016, 'Understanding the systemic interactions between primary tumors and disseminated tumor initiating cells', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, San Diego, CA, presented at AACR Special Conference on Function of Tumor Microenvironment in Cancer Progression, San Diego, CA, 07 January 2016 - 10 January 2016, http://dx.doi.org/10.1158/1538-7445.TME16-PR13

Scheel C; NgEaton E; Li SH-J; Chaffer CL; Reinhardt F; Kah K-J; Bell G; Guo W; Rubin J; Richardson A; Weinberg RA, 2011, 'Formation and maintenance of mesenchymal and stem-cell states in the breast by paracrine and autocrine signals', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.AM2011-LB-108

Chaffer CL; Thompson EW; Williams ED, 2007, 'Mesenchymal to epithelial transition in development and disease', in Cells Tissues Organs, pp. 7 - 19, http://dx.doi.org/10.1159/000101298

Williams E; Chaffer C; Oakes SR; Ormandy CJ; Blick T; Thompson E, 2007, 'Mesenchymal to epithetial transition in the establishment of secondary tumours: insights from a bladder carcinoma progression series', in Clinical and Experimental Metastasis, Kluwer Academic Publ, pp. 262 - 262, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000248687200097&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Williams ED; Chaffer CL; Oakes SR; Ormandy CJ; Blick T; Thompson EW, 2006, 'Mesenchymal to epithelial transition in the establishment of secondary tumors: Insights from a bladder carcinoma progression series', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000454606204397&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Brennan JP; Chaffer CL; Slavin J; Temelcos C; Goad J; Williams ED, 2006, 'Patterns of spread in an orthotopic mouse model of bladder cancer', in BJU INTERNATIONAL, BLACKWELL PUBLISHING, pp. 9 - 9, http://dx.doi.org/10.1111/j.1464-410X.2006.06085_31.x

Brennan JP; Williams ED; Chaffer CL; Goad J; Temelcos C; Slavin J, 2005, 'A novel orthotopic model of muscle-invasive bladder cancer', in BJU INTERNATIONAL, BLACKWELL PUBLISHING, Melbourne, AUSTRALIA, pp. 27 - 27, presented at Annual Scientific Meeting of the Urological- Society-of-Australasia, Melbourne, AUSTRALIA, 13 February 2005 - 17 February 2005, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000236061300125&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1


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