Select Publications

Journal articles

San Juan BP; Garcia-Leon MJ; Rangel L; Goetz JG; Chaffer CL, 2019, 'The complexities of metastasis', Cancers, vol. 11,

Chaffer CL; Goetz JG, 2018, 'CD44 Orchestrates Metastatic Teamwork', Developmental Cell, vol. 47, pp. 691 - 693,

Castaño Z; San Juan BP; Spiegel A; Pant A; DeCristo MJ; Laszewski T; Ubellacker JM; Janssen SR; Dongre A; Reinhardt F; Henderson A; del Rio AG; Gifford AM; Herbert ZT; Hutchinson JN; Weinberg RA; Chaffer CL; McAllister SS, 2018, 'IL-1β inflammatory response driven by primary breast cancer prevents metastasis-initiating cell colonization', Nature Cell Biology, vol. 20, pp. 1084 - 1097,

Li J; Choi PS; Chaffer CL; Labella K; Hwang JH; Giacomelli AO; Kim JW; Ilic N; Doench JG; Ly SH; Dai C; Hagel K; Hong AL; Gjoerup O; Goel S; Ge JY; Root DE; Zhao JJ; Brooks AN; Weinberg RA; Hahn WC, 2018, 'An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer', eLife, vol. 7,

van Dijk D; Sharma R; Nainys J; Yim K; Kathail P; Carr AJ; Burdziak C; Moon KR; Chaffer CL; Pattabiraman D; Bierie B; Mazutis L; Wolf G; Krishnaswamy S; Pe'er D, 2018, 'Recovering Gene Interactions from Single-Cell Data Using Data Diffusion', Cell, vol. 174, pp. 716 - 729.e27,

Bierie B; Pierce SE; Kroeger C; Stover DG; Pattabiraman DR; Thiru P; Donaher JL; Reinhardt F; Chaffer CL; Keckesova Z; Weinberg RA, 2017, 'Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells', Proceedings of the National Academy of Sciences of the United States of America, vol. 114, pp. E2337 - E2346,

Chaffer CL; San Juan BP; Lim E; Weinberg RA, 2016, 'EMT, cell plasticity and metastasis', Cancer and Metastasis Reviews, vol. 35, pp. 645 - 654,

Katajisto P; Döhla J; Chaffer CL; Pentinmikko N; Marjanovic N; Iqbal S; Zoncu R; Chen W; Weinberg RA; Sabatini DM, 2015, 'Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness', Science, vol. 348, pp. 340 - 343,

Chaffer CL; Weinberg RA, 2015, 'How does multistep tumorigenesis really proceed?', Cancer Discovery, vol. 5, pp. 22 - 24,

Marjanovic ND; Weinberg RA; Chaffer CL, 2013, 'Poised with purpose: Cell plasticity enhances tumorigenicity', Cell Cycle, vol. 12, pp. 2713 - 2714,

Chaffer CL; Marjanovic ND; Lee T; Bell G; Kleer CG; Reinhardt F; D'Alessio AC; Young RA; Weinberg RA, 2013, 'XPoised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity', Cell, vol. 154, pp. 61,

Marjanovic ND; Weinberg RA; Chaffer CL, 2013, 'Cell plasticity and heterogeneity in cancer', Clinical Chemistry, vol. 59, pp. 168 - 179,

Scheel C; Eaton EN; Li SHJ; Chaffer CL; Reinhardt F; Kah KJ; Bell G; Guo W; Rubin J; Richardson AL; Weinberg RA, 2011, 'Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast', Cell, vol. 145, pp. 926 - 940,

Chaffer CL; Brueckmann I; Scheel C; Kaestli AJ; Wiggins PA; Rodrigues LO; Brooks M; Reinhardt F; Suc Y; Polyak K; Arendt LM; Kuperwasser C; Bierie B; Weinberg RA, 2011, 'Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state', Proceedings of the National Academy of Sciences of the United States of America, vol. 108, pp. 7950 - 7955,

Chaffer CL; Weinberg RA, 2011, 'A perspective on cancer cell metastasis', Science, vol. 331, pp. 1559 - 1564,

Chaffer CL; Weinberg RA, 2010, 'Cancer cell of origin: Spotlight on luminal progenitors', Cell Stem Cell, vol. 7, pp. 271 - 272,

Tilkorn DJ; Lokmic Z; Chaffer CL; Mitchell GM; Morrison WA; Thompson EW, 2010, 'Disparate companions: Tissue engineering meets cancer research', Cells Tissues Organs, vol. 192, pp. 141 - 157,

Gupta PB; Chaffer CL; Weinberg RA, 2009, 'Cancer stem cells: Mirage or reality?', Nature Medicine, vol. 15, pp. 1010 - 1012,

Chaffer CL; Dopheide B; Savagner P; Thompson EW; Williams ED, 2007, 'Aberrant fibroblast growth factor receptor signaling in bladder and other cancers', Differentiation, vol. 75, pp. 831 - 842,

Chaffer CL; Brennan JP; Slavin JL; Blick T; Thompson EW; Williams ED, 2006, 'Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: Role of fibroblast growth factor receptor-2', Cancer Research, vol. 66, pp. 11271 - 11278,

Chaffer CL; Thomas DM; Thompson EW; Williams ED, 2006, 'PPARγ-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma', BMC Cancer, vol. 6,

Chaffer CL; Dopheide B; McCulloch DR; Lee AB; Moseley JM; Thompson EW; Williams ED, 2005, 'Upregulated MT1-MMP/TIMP-2 axis in the TSU-Pr1-B1/B2 model of metastatic progression in transitional cell carcinoma of the bladder', Clinical and Experimental Metastasis, vol. 22, pp. 115 - 125,

Chaffer CL; Morris MJ, 2002, 'The Feeding Response to Melanin-Concentrating Hormone Is Attenuated by Antagonism of the NPY Y1-Receptor in the Rat', Endocrinology, vol. 143, pp. 191 - 197,

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