By Dr Derrick Lau

Journal articles

Lau D; Márquez CL; Parker MW; Böcking T, 2022, 'Negative Staining Transmission Electron Microscopy of HIV Viral Particles Permeabilized with PFO and Capsid Stabilized with IP6', Bio-protocol, 12, http://dx.doi.org/10.21769/BioProtoc.4536

Yoh SM; Mamede JI; Lau D; Ahn N; Sánchez-Aparicio MT; Temple J; Tuckwell A; Fuchs NV; Cianci GC; Riva L; Curry H; Yin X; Gambut S; Simons LM; Hultquist JF; König R; Xiong Y; García-Sastre A; Böcking T; Hope TJ; Chanda SK, 2022, 'Recognition of HIV-1 capsid by PQBP1 licenses an innate immune sensing of nascent HIV-1 DNA', Molecular Cell, 82, pp. 2871 - 2884.e6, http://dx.doi.org/10.1016/j.molcel.2022.06.010

Lau D; Magnan C; Hill K; Cooper A; Gambin Y; Sierecki E, 2022, 'Single Molecule Fingerprinting Reveals Different Amplification Properties of α-Synuclein Oligomers and Preformed Fibrils in Seeding Assay', ACS Chemical Neuroscience, 13, pp. 883 - 896, http://dx.doi.org/10.1021/acschemneuro.1c00553

Leitão ADG; Rudolffi-Soto P; Chappard A; Bhumkar A; Lau D; Hunter DJB; Gambin Y; Sierecki E, 2021, 'Selectivity of Lewy body protein interactions along the aggregation pathway of α-synuclein', Communications Biology, 4, http://dx.doi.org/10.1038/s42003-021-02624-x

Bhumkar A; Magnan C; Lau D; Jun ESW; Dzamko N; Gambin Y; Sierecki E, 2021, 'Single-Molecule Counting Coupled to Rapid Amplification Enables Detection of α-Synuclein Aggregates in Cerebrospinal Fluid of Parkinson's Disease Patients', Angewandte Chemie - International Edition, 60, pp. 11874 - 11883, http://dx.doi.org/10.1002/anie.202014898

Bhumkar A; Magnan C; Lau D; Jun ESW; Dzamko N; Gambin Y; Sierecki E, 2021, 'Single‐Molecule Counting Coupled to Rapid Amplification Enables Detection of α‐Synuclein Aggregates in Cerebrospinal Fluid of Parkinson's Disease Patients', Angewandte Chemie, 133, pp. 11981 - 11990, http://dx.doi.org/10.1002/ange.202014898

Böcking T; Jacques DA; Lau D; Walsh JC; Dickson CF; Tuckwell A; Stear JH; Hunter DJB; Bhumkar A; Shah V; Turville SG; Sierecki E; Gambin Y, 2021, 'Rapid HIV-1 capsid interaction screening using fluorescence fluctuation spectroscopy', Analytical Chemistry, 93, pp. 3786 - 3793, http://dx.doi.org/10.1021/acs.analchem.0c04250

Lau D; Walsh JC; Mousapasandi A; Ariotti N; Shah VB; Turville S; Jacques DA; Böcking T, 2020, 'Self-Assembly of Fluorescent HIV Capsid Spheres for Detection of Capsid Binders', Langmuir, 36, pp. 3624 - 3632, http://dx.doi.org/10.1021/acs.langmuir.0c00103

Lau D; Walsh JC; Peng W; Shah VB; Turville S; Jacques DA; Böcking T, 2019, 'Fluorescence Biosensor for Real-Time Interaction Dynamics of Host Proteins with HIV-1 Capsid Tubes', ACS Applied Materials and Interfaces, 11, pp. 34586 - 34594, http://dx.doi.org/10.1021/acsami.9b08521

Márquez CL; Lau D; Walsh J; Faysal KMR; Parker MW; Turville SG; Böcking T, 2019, 'Fluorescence Microscopy Assay to Measure HIV-1 Capsid Uncoating Kinetics in vitro', Bio-protocol, 9, http://dx.doi.org/10.21769/BioProtoc.3297

Lau D; Walsh J; Peng W; Shah V; Turville S; Jacques D; Böcking T, 2019, 'Fluorescence biosensor for real-time interaction dynamics of host proteins with HIV-1 capsid tubes', , http://dx.doi.org/10.1101/619841

Peng W; Shi J; Márquez CL; Lau D; Walsh J; Faysal KMR; Byeon CH; Byeon IJL; Aiken C; Böcking T, 2019, 'Functional analysis of the secondary HIV-1 capsid binding site in the host protein cyclophilin A', Retrovirology, 16, http://dx.doi.org/10.1186/s12977-019-0471-4

Márquez CL; Lau D; Walsh J; Shah V; McGuinness C; Wong A; Aggarwal A; Parker MW; Jacques DA; Turville S; Böcking T, 2018, 'Kinetics of HIV-1 capsid uncoating revealed by single-molecule analysis', eLife, 7, http://dx.doi.org/10.7554/eLife.34772

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