Researcher

Dr Guozhen Liu

My Expertise

Chemical sensors and biosensors; Point-of-Care diagnostics; Stimuli-responsive nanoparticles; Nanoscale analysis; Electrochemistry; Nanofabrication; Surface Chemistry; Biomaterials; Precision diagnostics and therapeutics; Nanotechnology; Real-time in vivo sensing; Biomedical devices; Microfluidic paper based analytical devices.

Field of Research (FoR)

Sensor Technology (Chemical aspects); Electroanalytical Chemistry; Immunological and Bioassay Methods; Nanobiotechnology; Nanoscale characterisation; Nanomaterials; Nanomedicine; Biomedical engineering

Biography

Dr Guozhen Liu, an ARC Future Fellow, has taken a role as a Senior Lecturer at the Graduate School of Biomedical Engineering, UNSW in 2018. Before that, Dr Liu worked as an Associate Professor at Macquarie University. Gaining her PhD degree in Chemistry in 2006 under the supervision of Prof Justin Gooding at UNSW, Dr Liu is recognised for her innovative cross-disciplinary research in the area of nanotechnology, biosensors, and biomedical...view more

Dr Guozhen Liu, an ARC Future Fellow, has taken a role as a Senior Lecturer at the Graduate School of Biomedical Engineering, UNSW in 2018. Before that, Dr Liu worked as an Associate Professor at Macquarie University. Gaining her PhD degree in Chemistry in 2006 under the supervision of Prof Justin Gooding at UNSW, Dr Liu is recognised for her innovative cross-disciplinary research in the area of nanotechnology, biosensors, and biomedical devices. Dr Liu conducted her postdoctoral research at CSIRO (2006-2008) and UNSW (2008-2010), respectively before she accepted a faculty position as Associate Professor at the Central China Normal University, China (2010-2015). In 2015 Dr Liu moved back to Sydney and worked as Research Fellow at ARC Centre of Excellence for Nanoscale BioPhtotnics (CNBP) before she was awarded the prestigious ARC Future Fellowship in 2016. 

Dr Liu’s research career has alternated between industrial and academic research. Besides building effective collaborations within academia, Dr Liu has maintained close engagement with the industry sector in the conduction of translational research. Dr Liu’s industrial experience includes four years spent as R&D Manager for AgaMatrix Inc. (2010-2015), working for the US based company in China. This position saw her developing medical devices including glucose test strips and glucose meters. The sensing technologies described in her patents have attracted the attention and investment of industry end-users, such as MedImmune, Nutromics and Regeneus Ltd. These technologies have been, or are in the process of being commercialised, with one already available as a market product. Dr Liu has attracted more than $4M in national and international research funding since 2015.

Professional Interests

  • Member of IEEE
  • Member of Australian Diabetes Society
  • Member of Engineering in Medicine and Biology Society
  • Chartered member of Royal Australian Chemical Institute (RACI)
  • Member of American Chemical Society
  • Member of Chinese Chemical Society
  • Member of International Society of Aptamers (INSOAP)

Visit Dr Guozhen Liu's research web pages:

https://guozhenliu.weebly.com

https://research.unsw.edu.au/people/dr-guozhen-liu


My Grants

 

  • Australian Research Council Linkage Project (LP180100801), 2019-2022, $475,000, Guozhen Liu, Nigel Lovell. Kourosh Kalantar-Zadeh, Margaret Morris, Peter Vranes
  • UNSW Biomedical Engineering Seed Fund, 2019-2022, $450,000, Guozhen Liu, Margaret Morris, Jerry Greenfield, Maria Craig, Peter Vranes
  • Cooperative Research Centres Project (CRC-P) Grant with Nutromics, 2019-2021, $2.15M, Guozhen Liu (Lead CI at UNSW)
  • MedImmune Industry Funding, 2018-2019, $591,000, Guozhen Liu
  • Australian Research Council  Future Fellowship (FT160100039), 2017-2021, $652,000, Guozhen Liu
  • ANSTO PhD Project Funding, 2018-2019, $7,500, Guozhen Liu (for PhD student Jagjit Kaur)
  • ANSTO PhD Project Funding, 2017-2018, $7,500, Guozhen Liu (for PhD student Fuyuan Zhang)
  • Macquarie University Research Infrastructure Block Grant for 3D-printer for biomedical applications, 2017, $100,000
  • Australian Research Council  Linkage Project, 2016-2019, $342,000, Ewa Goldys, Guozhen Liu, Graham Vesey
  • Macquarie University Research Development Grant, 2015-2016, $50,000, Guozhen Liu, Ewa Goldys, Ayad Anwar
  • Macquarie University Research Infrastructure Block Grant, 2015, $100,000
  • Regeneus Inc. Industry Funding, 2015, $75,000, Guozhen Liu, Ewa Goldys
  • National Natural Science Foundation of China General Project Funding, 2016-2019, Guozhen Liu
  • Central China Normal University Infrastructure Funding, 2014, China
  • Ministry of Education Self-determined Research Funding, 2013-2016, China
  • Wuhan Rongtan Tech, Industry Funding, 2011-2012, China
  • National Natural Science Foundation of China Early Career Research Funding, 2010-2012, China
  • Central China Normal University New Staff Funding, 2010, China
  • International Postgraduate Scholarship (IPRS) 2003, awarded by Australian government

My Qualifications

  • PhD in Chemistry, School of Chemistry, University of New South Wales, Australia (2003 –2006) under the supervising of Prof Justin Gooding
  • Master in Analytical Chemistry, College of Material Science and Chemical Engineering, China University of Geosciences, China (1997-2000)
  • Bachelor in Chemical Education, Department of Chemistry, Hubei Normal University, China (1993-1997)

My Awards

 

  • The second prize of Innovation and Entrepreneurship Competition for Overseas High-level Talents 2018, China, Australia and South Africa
  • The Rising Star Award, Australian Association of Chinese Biomedical Scientists, 2018, Australia
  • Academic Excellence Award for transdisciplinary research publications in 2017, Australia
  • ARC Future Fellowship, 2016, Australia
  • Shortlisted by Georgina Sweet Award for Women in Quantitative Biomedical Science 2016, Australia
  • Travel grant and Childcare grant for Emerging Therapeutics Summit 2016, Melbourne, awarded by International Innovative Research Network
  • Best Poster Award, CNBP Annual Retreat 2015, Lake Macquarie, Australia
  • International Postgraduate Scholarship (IPRS) 2003, awarded by Australian government

My Research Activities

Dr Liu is leading a research team on Integrated Devices and Intelligent Diagnostics (ID2, https://guozhenliu.weebly.com/) covering the area of point-of-care testing, nanoscale analysis, stimuli-responsive nanoparticles, advanced sensing technologies and biomedical devices. Liu’s group targets to “Creating tools to quantify our health” where she modifies the bio-nano interfaces for diagnostic medical devices, bioimaging and biomaterials as well as more fundamental research on real-time in vivo sensing and adaptive cellular response systems. Besides the biomedical research, the group is also interested in the development of assays and portable devices for food safety. 

          Current research projects:

  • Smart sensing platforms for detection of key analytes in the body such as insulin, glucose, cytokines, microRNA, nucleic acids, exosomes, and ROS/RNS
  • Stimuli-responsive nanoparticles towards intelligent personialised nanomedicine
  • 3D microfluidic paper based point-of-care devices
  • Pathogen and toxin detection in foods and agriculture
  • Single cell analysis
  • Wearable and implantable in vivo devices 

    Patents:

  • CRISPR/CAS based non-nucleic acid target biosensing system, G. Liu, Y. Li, Australian provisional patent No.: 2019901593
  • A composite and sensing device for point-of-care bioanalysis, G. Liu, Australian provisional patent.: 2019900402
  • An electrochemical real-time detection system based on DNA switches, G. Liu, C. Cao, Chinese Patent No.: ZL 201710031366.9 (Granted at China)
  • Methods for detecting a biological molecule, G. Liu, Australian provisional patent.: 2018904363
  • Cell selection method, G. Liu, E.M. Goldys, A. Anwer, Australian provisional patent No.: 2015904816
  • Biological detection system, G. Liu, E.M. Goldys, US patent application No.: 16/061, 218, 2018
  • Electrochemical affinity sensor, J.J. Gooding, G. Liu, Patent No.: US 20140174949 A1
  • Electrochemical competition sensor, J.J. Gooding, G. Liu, Patent No.: US 20140174950 A1
  • A method for in situ covalent attachment of gold nanoparticles to surfaces, G. Liu, W. Guo, Chinese Patent No.: ZL 2013 1 0164582.2 (Granted at China)
  • Chelating amphiphiles, M.J. Maghaddam, C.J. Drummond, G. Liu, Patent No.: WO2010139003 A1
  • Electrochemical Sensor, J.J. Gooding, G. Liu, Patent No.: US 8110079 B2 (Granted at US) 

          Refereed Journal Articles (Names underlined were students or postdocs under Liu's supervision; *corresponding author; Google citations: https://scholar.google.com.au/citations?user=xms_zr0AAAAJ&hl=en)

         2019

  • G. Liu*, C. CaoH. Wei, S. Feng, S. NiOn-Chip Structure-Switching Aptamer Modified Magnetic Nanobeads for Continuous Monitoring of Interferon-gamma Ex Vivo, Microsystems & Nanoengineering, 2019, accepted, [IF=5.1]
  • B. V. Dang, A. Hassanzadeh-Barforoushi, M. S. Syed, D. Yang, S.-J. Kim, R. Taylor, G.-J. Liu, G. Liu*, Tracie Barber*Microfluidic actuation via 3D-printed molds towards multiplex biosensing of cell apoptosisACS Sensors, 2019, accepted [IF=6.9]
  • Y. Li, L. Liu, G. Liu*CRISPR/Cas multiplexed biosensing: a challenge or an insurmountable obstacle? Trend in Biotechnology, 2019, I:https://doi.org/10.1016/j.tibtech.2019.04.012 [IF=13.6]
  • Y. Alhamoud, D, Yang, S. S. F. Kenston, G. Liu, L. Liu, H. Zhou, F. Ahmed, J. Zhao, Advanced in biosensors for the detection of ochratoxin A: Bioreceptors, nanomaterials, and their applicationsBiosens. Bioelectron., 2019, 141, 11418 [IF=9.5]
  • T. Jiang, L. Zhou, H. Liu, P. Zhang, G. Liu, P. Gong, C. Li, W. Tan, J. Chen, L. Cai, A Monitorable Mitochondria-targeting DNAtrain for Image-guided Synergistic Cancer Therapy, Anal. Chem. 2019, 91, 6996-7000DOI: 10.1021/acs.analchem.9b01777 [IF=6.3]
  • K. Wen, X. Xu, J. Chen, L. Lv, L. Wu, Y. Hu, X. Wu, A. Peng, G. Liu,  H. Huang,  Triplet Tellurophene-based Semiconducting Polymer Nanoparticles for Near-Infrared-mediated Cancer TheranosticsACS Appl. Mater. Interfaces, 2019, 11, 19, 17884-17893,  https://pubs.acs.org/doi/10.1021/acsami.9b05196 [IF=8.1]
  • F. Deng, E.M. Goldys, G. Liu*, Molecularly imprinted polymer-based reusable biosensing device on stainless steel for spatially localized detection of cytokine IL-1β, Sensors and Actuators B: Chemical, 2019, 292, 277-283, https://doi.org/10.1016/j.snb.2019.04.142 [IF=5.7]
  • L. LiuD. YangG. Liu*Signal amplification strategies for paper-based analytical devicesBiosens. Bioelectron., 2019, 136, 60-75. http://authors.elsevier.com/sd/article/S0956566319303355 [IF=8.2]
  • F. ZhangF. Deng, G-J Liu, R. Middleton, D. Inglis, A. Anwer, S. Wang, G. Liu*, IFN-γ-induced signal-on fluorescence aptasensors: from hybridization chain reaction amplification to 3D optical fiber sensing interface towards a deployable device for cytokine sensingMolecular Systems Design & Engineering, 2019, in press https://pubs.rsc.org/en/Content/ArticleLanding/2019/ME/C9ME00047J#!divAbstract
  • Y. Li, S. Li, J. Wang, G. Liu*CRISPR/Cas systems towards next generation biosensing, Trends in Biotechnology2019, 37 (7), 730-743, DOI: https://doi.org/10.1016/j.tibtech.2018.12.005 [Review paper]
  • K. Ma, G-J. Liu, L. Yan, S. Wen, B. XU, W. Tian, E. Goldys, G. Liu*AIEgen based PLGA magnetic nanoparticles to localize cytokine VEGF for early diagnosis and photothermal therapyNanomedicine, 2019, in press, https://www.futuremedicine.com/doi/full/10.2217/nnm-2018-0467
  • F. Zhang, L. Liu, S. Ni, J. Deng, G.J. Liu, R. Middleton, D. Inglis, S. Wang, G. Liu*, Turn-on fluorescence aptasensor on magnetic nanobeads for aflatoxin M1 detection based on an Exonuclease III assisted signal amplification strategy, Nanomaterials, 2019, 9(104), 1-13
  • W. Wu, M. Jia, Z. Wang, W Zhang, Q. Zhang, G. Liu, Z. Zhang, P. Li, Simultaneous voltammetric determination of cadmium(II), lead(II), mercury(II), zinc(II), and copper(II) using a glassy carbon el ectrode modified with magnetite (Fe3O4) nanoparticles and fluorinated multiwalled carbon nanotubes, Microchimica Acta, 2019, 186:97, https://doi.org/10.1007/s00604-018-3216-5
  • J. Kaur, C. Jiang, G. Liu*Different strategies for detection of HbA1c emphasizing on HbA1c biosensors and point-of-care analyzersBiosens. Bioelectron., 2019, 123, 85-100 [Review paperhttps://doi.org/10.1016/j.bios.2018.06.018

         2018

  • H. WeiS.N. NiC.M. Cao, G. F. Yang, G. Liu*Graphene oxides signal reporters based multifunctional immunosensing platform for amperometric profiling of multiple cytokines in serum, ACS Sens., 2018, 3(8), 1553-1561
  • C. Cao. R. Jin, H. Wei, et al, G. Liu*Graphene Oxide Based Recyclable In vivo Device for Amperometric Monitoring of Interferon-γ in Inflammatory MiceACS Appl. Mater. Interfaces, 2018, 10(39), 33078-33087
  • J. Li, et al, G. Liu, et al, Perspective: Biomedical sensing and imaging with optical fibers—Innovation through convergence of science disciplinesAPL Photonics, 2018, 3, 100902
  • K. Zhang, M.V. Baratta, G. Liu*, M.G. Frank, N.R. Leslie, L.R. Watkins, S.F. Maier, M.R. Hutchinson, E.M. Goldys, A novel platform for in vivo detection of cytokine release within discrete brain regionsBrain Behav. Immu., 2018, S0889-159(18), 30130-30132. https://doi.org/101016/j.bbi.2018.04.011
  • F. Zhang, B. Liu, G. Liu, W. Sheng, Y. Zhang, Q. Liu, S. Wang, Novel magnetic nanobeads-based fluoroimmunoassays for zearalenone detection in cereals using protein G as the recognition linkerSens. Actuators B Chem., 2018, 270, 149-157https://doi.org/10.1016/j.snb.2018.04.131
  • C.M. CaoF. Zhang, E. M. Goldys, F. GaoG. Liu*Advances in structure-switching aptasensing towards real-time detection of cytokinesTrAC Trends Anal. Chem., 2018, 102, 379-396 [Review paper]
  • F. Zhang, B. Liu, G. Liu, Y. Zhang, J. Wang, S. Wang, Substrycture-activity relationship studies on antibody recogntion for phenylurea compounds using immunoassay and computational chemistrySci. Rep., 2018,  8(3131), 1-8. https://doi.org/10.1016/j.trac.2018.03.002
  • K. Ma, F., Zhang, N. Sayyadi, W. J. Chen, A. Anwer, A. Care, B. Xu, W. J. Tian, E. M. Goldys,G. Liu*, Turn-on fluorescent aptasensor based on AIEgen labelling for the localisation of IFN-y in live cells, ACS Sens., 2018, 3(2), 320-326. https://pubs.acs.org/doi/10.1021/acssensors.7b00720
  • K.X. Zhang, G. Liu*, E.M. Goldys, Robust immunosensing system based on biotin-streptavidin coupling for spatially localized femtogram mL-1 level detection of interleukin-6, Biosens. Bioelectron., 2018, 102, 80-86. https://doi.org/10.1016/j.bios.2017.11.023

          2017

  • M. Qi, J.W. Huang, H. WeiC.M. Cao, S.L. Feng, Q. Guo, E.M. Goldys, R. Li, G. Liu*,Graphene oxide thin film with dual function integrated into a nano-sandwich device for in vivo monitoring of interleukin-6, ACS Appl. Mater. Interfaces, 2017, 9(48), 41659-41668. https://pubs.acs.org/doi/pdf/10.1021/acsami.7b10753
  • S.L. Feng, G. Liu, L. Jiang, Y. Zhu, E.M. Goldys, D.W. Inglis, A microfluidic needle for sampling and delivery of chemical signals by segmented flows, Appl. Phys. Lett, 2017, 111, 183702.
  • S.L. Feng, A.M. Skelley, A.G. Anwer, G. Liu, D.W. Inglis, Maximizing Particle Concentration in Deterministic Lateral Displacement Arrays, Biomicrofluidics, 2017, 11, 024121.
  • G. Liu*, K. Zhang, K. Ma, A. Care, M.R. Hutchinson, E. M. Goldys, Graphene quantum dots based "switch-on" nanosensors for intracellular cytokine monitoringNanoscale, 2017, 9, 4934-4943.
  • C.M. CaoY. Zhang, C. Jiang, M. QiG. Liu*, Advances on Aryldiazonium Salt Chemistry Based Interfacial Fabrication for Sensing Applications, ACS Appl. Mater. Interfaces, 2017, 9(6), 5031-5049. [Review paper]
  • A. Rehman, A. Anwer, M, Gosnell, S. Mahbub, G. Liu, E.M. Goldys, Fluorescence quenching of free and bound NADH in Hela cells determined by hyperspectral imaging nad unmixing of cell autofluorescenceBiomed. Opt. Express, 2017, 8(3), 1488-1498
  • G. Liu*, K.X. Zhang, A. Nadort, M.R. Huctchinson, E.M. Goldys, Sensitive cytokine assay based on optical fiber allowing localised and spatially resolved detection of interleukin-6ACS Sens., 2017, 2(2), 218-226.
  • C. Jiang, S.M. Silva, S. Fan, Y. Wu, M.T. Alam, G. Liu, J.J. Gooding, Aryldiazonium elelctrochemistry derived mixed organic layers: from surface chemistry to its applicationsJ. Electroanal. Chem, 2017, 785, 265-278. [Review paper]
  • Y. Lu, Y. Xia, G. Liu, M. Pan, M. Li, N. A. Lee, S. Wang, A Review of Methods for Detecting Melamine in Food Samples, Crit. Rev. Anal. Chem., 2017, 47(1), 51-66.[Review paper]

          2016

  • X. GongG. Liu, Y. Li, Y. Yu, W.Y. Teoh, Functionalized-graphene composites: Fabrication and applications in sustainable energy and environment, Chem. Mater., 2016, 28(22), 8082-8118.[Review paper]
  • M. QiY. Zhang, C.M. Cao, M. Zhang, S. Liu, G. Liu*Decoration of RGO nanosheets with aryldiazonium salt and gold nanoparticles towards a label-free amperimetric immunosensor for detecting TNF-a in live cellsAnal. Chem., 2016, 88(19), 9614-9621.
  • M. QiY. Zhang, C.M. Cao, Y. Lu, G. Liu*, Increased sensitivity of extracellular glucose monitoring based on AuNP decorated GO nanocompositesRSC Adv., 2016, 6, 39180-39187.
  • Y. Lu, M. Li, M. Ding, G. Liu, Y. Zhang, S.Wang, Detection of biosphenol-A with electrochemical immunosensor: The comparison of the competition and displacement format assayJ. Electroanal. Chem., 2016, 779, 34-38.
  • G. Liu*M. Qi, M. Hutchinson, G. Yang, E.M. Goldys, Recent Advances in Cytokine Detection by ImmunosensingBiosens. Bioelectron., 2016, 79, 810-821. [Review paper]
  • G. Liu*M. QiY. ZhangC.M. Cao, E.M. Goldys, Nanocomposites of Gold Nanoparticles and Graphene Oxide Towards an Stable Label-Free Electrochemical Immunosensor for Detection of Cardiac Marker TroponinI, Anal. Chim. Acta, 2016, 909, 1-8. [Front cover feature article]
  • D. Song, C. Guo, J. Zhao, H. Suo, X. Zhao, G. LiuHost Sensitized Near-infrared Emission in Nd3+ -Yb3+ Co-doped Na2GdMg2V3O12 PhosphorCeram. Int., 2016, 42(11):12988-12994
  • W. Z. W. Ismail, G. Liu, K. Zhang, E.M. Goldys, J.M. Dawes, Dopamine Sensing and Measurement using Threshold and Spectral Measurements in Random Lasers,Opt. Express, 2016, 24(2), A85-A91.

          2015

  • G. Liu*, Y. ZhangM. Qi, F. Chen, Covalent Anchoring of Multifunctionized Gold Nanoparticles on Electrodes towards an Electrochemical Sensor for Detection of Cadmium IonsAnal. Methods, 2015, 7, 5619-5626.
  • Y. ZhangM. QiG. Liu*, C-C Bonding of Graphene Oxide on 4-Aminophenyl Modified Gold Electrodes towards Simultaneous Detection of Heavy Metal IonsElectroanalysis, 2015, 27 (5), 1110-1118.
  • G. Liu*, Y. ZhangW. GuoCovalent Functionalization of Gold Nanoparticles as Electronic Bridges and Signal Amplifiers Towards an Electrochemical Immunosensor for Botulinum Neurotoxin Type ABiosens. Bioelectron., 2014, 61, 547-553.

         2014

  • X. Gong, Y. Bi, Y. Zhao, G. Liu, W.Y. Teoh, Graphene Oxide-based Electrochemical Sensor: a Platform for Ultrasensitive Detection of Heavy Metal Ions, RSC Advances, 2014, 4 (47), 24653-24657.
  • F. Chen, G. Liu, Y. Shi, P. Xi, J. Cheng, J. Hong, R. Shen, X. Yao, D. Bai, Z. Zeng, A Coumarin-derived Fluorescent Chemosensor for Selectively Detecting Cu2+: Synthesis, DFT Calculations and Cell Imaging ApplicationsTalanta, 2014, 124(15), 139-145.
  • G. Liu*, W. GuoY. ZhangCovalent Fabrication of Methyl Parathion Hydrolase on Gold Nanoparticles Modified Carbon Substrates for Designing a Methyl Parathion Biosensor,Biosens. Bioelectron., 2014,53 (15), 440-446.
  • G. Liu*, W. Guo, D. Song, A Multianalyte Electrochemical Immunosensor Based on Patterned Carbon Nanotubes Modified Substrates for Detection of Pesticides,Biosens. Bioelectron., 2014, 52 (15), 360-366.
  • A. Li, J. Liu, G. Liu, J. Zhang, S. Feng, Design and Synthesis of Fluorescent Core-shell Nanoparticles with Tunable LCST Behavior and Metal-enhanced Fluorescence,J. Polym. Sci. Part A: Polym. Chem., 2014, 52(1), 87-95.
  • C. Fairman, M. Chockalingam, G. Liu, A.H. Soeriyadi, J.J. Gooding. Light-Induced Organic Monolayer Modification of Iodinated Carbon Electrodes, Langmuir,2014, 30, 332−339.

         2013

  • W. GuoF. Jiang, J. Chu, D. Song, G. Liu*, A Sensitive Hydrogen Peroxide Biosensor Based on Aryldiazonium salts and SWNTs Modified Gold Electrodes, J. Electroanal. Chem., 2013, 703, 63-69.
  • U.E. Wawrzyniak, P. Ciosek, M. Zaborowski, G. Liu, J.J. Gooding. Gly-Gly-His Immobilized On Monolayer Modified Back-Side Contact Miniaturized Sensors for Complexation of Copper Ions,Electroanalysis, 2013, 25(8), 1-11.
  • F. Chen, P. Xi, C. Ma, C. Shao, J. Wang, S. Wang, G. Liu, Z. Zeng. In Situ Preparation, Characterization, Magnetic and Catalytic Studies of Surfactant Free RGO/FexCo100−xnanocomposites, Dalton Trans., 2013, 42, 7936-7942.
  • G. Liu*, D. Song, F. Chen. Towards the Fabrication of a Label-free Amperometric Immunosensor Using SWNTs for Direct Detection of ParaoxonTalanta, 2013, 104, 103-108.
  • G. Liu, S.G. Iyengar, J.J. Gooding. An Amperometric Immunosensor Based on a Gold Nanoparticle-Diazonium Salt Modified Sensing Interface for the Detection of HbA1c in Human Blood, Electroanalysis, 2013, 25(4), 881-887.

          2012

  • G. Liu*S. Wang, J. Liu, D. Song. An Electrochemical Immunosensor Based on Chemical Assembly of Vertically Aligned Carbon Nanotubes on Carbon Substrates for Direct Detection of Pesticide Endosulfan in Environmental WaterAnal. Chem., 2012, 84(9), 3921-3928.
  • X. Luo, J. Liu, G. Liu, R. Wang, Z. Liu. Manipulation of the Bioactivity of Glucose Oxidase via RAFT Controlled Surface Modification, J. Polym. Sci. Part A: Polym. Chem., 2012, 50(14), 2786-2793.
  • G. LiuS.M. Khor, S.G. Iyengar, J.J. Gooding. Development of an Electrochemical Immunosensor for the Detection of HbA1c in Serum, Analyst, 2012, 137, 829-832.
  • G. Liu, S.G. Iyengar, J.J. Gooding. An Electrochemical Impedance Immunosensor Based on Gold Nanoparticle-Modified Electrodes for the Detection of HbA1c in Human Blood,Electroanalysis, 2012, 24(7), 1509-1516.

          2011

  • G. LiuModification of Aryldiazonium Salts on Electrodes towards Designing Stable and Versatile Sensing Interfaces, Aus. J. Chem., 2011, 64, 658.
  • G. Liu, J. Liu, T.P. Davis, J.J. Gooding. Electrochemical Impedance Immunosensor Based on Gold Nanoparticles and Aryldiazonium Salts Functionalized Gold Interface for the Detection of AntibodyBiosens. Bioelectron., 2011, 26(8), 3660-3665.
  • G. Liu, E. Luais, J.J. Gooding. The Fabrication of Stable Gold nanoparticle Modified Interfaces for Electrochemistry, Langmuir, 2011, 27(7), 4173-4186.
  • G. Liu, N.M.K. Tse, M.R. Hill, D.F. Kennedy, C.J. Drummond, Disordered Mesoporous Gadolinosilicate Nanoparticles Prepared Using Gadolinium Based Ionic Liquid Emulsions: Potential as Magnetic Resonance Imaging Contrast Agent, Aus. J. Chem., 2011, 64, 617-624.
  • S.M. Khor, G. Liu, J.R. Peterson, S.G. Iyengar, J.J. Gooding. An Electrochemical Immunobiosensor for Direct Detection of Veterinary Drug Residues in Undiluted Complex MatricesElectroanalysis, 2011, 23(8), 1797-1804.
  • S.M. Khor, G. Liu, S.G. Iyengar, J.J. Gooding. The Importance of Interfacial Design for the Sensitivity of a Label-Free Electrochemical Immuno-Biosensor for Small Organic Molecules.Biosens. Bioelectron., 2011, 26(5), 2038-2044.
  • X. Chen, M. Chockalingam, G. Liu, E. Luais, A.L. Gui, J.J. Gooding, A Molecule with Dual Functionality 4-Aminophenylmethylphosphonic Acid: A Comparison Between Layers Formed on Indium Tin Oxide by In Situ Generation of an Aryl Diazonium Salt or by Self-Assembly of the Phosphonic Acid, Electroanalysis, 2011, 23(11), 2633-2642.
  • C. Hua, W. H. Zhang, S.R. M.D. Almeida, S. Ciampi, D. Gloria, G. Liu, J.B. Harper, J.J. Gooding, A Novel Route to Copper(II) detection Using ‘Click’ Chemistry-induced Aggregation of Gold NanoparticlesAnalyst, 2011, 137, 82-86. [Front cover feature article]

          2010

  • A.L. GuiG. Liu, M. Chockalingam, G.L. Saux, J.B. Harper, J.J. Gooding. A Comparative Study of Modifying Gold and Carbon Electrode with 4-nitrophenyl Diazonium SaltElectroanalysis, 2010, 22(16), 1824-1830.
  • A.L. Gui, G. Liu, M. Chockalingam, G.L. Saux, J.B. Harper, J.J. Gooding. A Comparative Study of Modifying Gold and Carbon Electrode with 4-sulfophenyl Diazonium SaltElectroanalysis, 2010, 22(12), 1283-1289.
  • G. Liu, M. Chockalingham, S.M. Khor, A.L. Gui, J.J. Gooding. A Comparative Study of the Modification Gold and Glassy Carbon Surfaces with Mixed Layers of In situ Generated Aryl Diazonium Compounds. Electroanalysis, 2010, 22(9), 918-926

          2009

  • G. Liu, C.E. Conn, L. Waddington, S.T. Mudie, C.J. Drummond. Colloidal Amphiphiles Self-Assembly Particles Comprised of Gadolinium Oleate and Myverol: Evaluation as Contrast Agents for Magnetic Resonance Imaging. Langmuir, 2009, 26(4), 2383-2391.
  • G. Liu, C.E. Conn, C.J. Drummond. Lanthanide Metal Oleates: Chelation, Self-Assembly and Exemplification of ordered Nanostructured Colloidal Contrast Agents for Medical Imaging. J. Phys. Chem. B, 2009, 113(49), 15949-15959.
  • G. Liu, J.J. Gooding. Towards the Fabrication of Label-free Amperometric Immunosensors Using SWNTs. Electrochem. Commun., 2009, 11: 1982-1985.

          2008

  • G. Liu, M.N. Paddon-Row, J.J. Gooding. Protein Modulation of Electrochemical Signals: Application to Immunobiosensing. Chem. Commun., 2008, 3870-3872.
  • C. Fairman, S.S.C. Yu, G. Liu, A.J. Downard, B.D. Hibbert, J.J. Gooding. Exploration of Variables in the Fabrication of Pyrolysed Photoresist. J. Solid State Electrochem., 2008, 12(10): 1357-1365.

          2007

  • G. Liu, M.N. Paddon-Row, J.J. Gooding. Molecular Wire Modified Glassy Carbon Electrode for Achieving Direct Electron Transfer to Native Glucose Oxidase.Electrochem. Commun., 2007, 9(9): 2218-2223.
  • G. Liu, T. Böcking, J.J. Gooding. Diazonium salts: Stable Monolayers on Gold Electrodes for Sensing Applications. J. Electroanal. Chem., 2007, 600(2):335-344.

          2006

  • G. Liu, J.J. Gooding. An Electrochemical Interface Comprising Molecular Wires and Poly(ethylene glycol) Spacer Units Self-Assembled on Carbon Electrodes for Studies of Protein Electrochemistry. Langmuir, 2006, 22(17):7421-7430.
  • G. Liu, Q.T. Nguyen, E. Chow, T. Bocking, D.B. Hibbert, J.J. Gooding. Study of Factors Affecting the Performance of Voltammetric Copper Sensors based on Gly-Gly-His Modified Glassy Carbon and Gold Electrodes. Electroanalysis, 2006 18(12): 1141-1151.

          2005

  • G. Liu, J. Liu, T. Böcking, P.K. Eggers, .J.J. Gooding. The Modification of Glassy Carbon and Gold Electrodes with Aryl Diazonium Salt: The Impact of the Electrode Materials on the Rate of Heterogeneous Electron Transfer. Chem. Phys., 2005, 319: 136-146.

          Scholarly Book Chapters

  • J.J. Gooding, G. LiuA.L. Gui. Book chapter 9: The Use of Aryl Diazonium Salts in the Fabrication of Biosensors and Chemical Sensors, in book Aryl Diazonium Salts: New Coupling Agents and Surface Science 2012, Wiley publisher, p.197-218 

           Research in Media Coverage:

https://www.theweek.in/news/health/2019/08/12/australian-health-start-ups-eye-indian-market.html

https://www.engineering.unsw.edu.au/news/cytokine-research-opens-window-onto-live-brain-processes

https://www.mq.edu.au/research-impact/2016/11/11/developing-novel-nano-tools-to-better-understand-the-brain/#.WP5bPNKGMtI

http://www.arc.gov.au/nanoscale-sensor-spot-disease

https://www.photonics.com/Article.aspx?AID=61870

https://phys.org/news/2017-03-nanoscale-sensor-disease.html

http://www.researchcareer.com.au/news/cytokine-sensor-to-see-sub-cellular

http://getstem.com.au/nanoscale-sensor-spot-disease/

https://www.eedesignit.com/diseases-to-be-detected-with-nanoscale-sensor/

https://www.mdtmag.com/news/2017/03/nanoscale-sensor-spot-disease

http://www.mq.edu.au/newsroom/2015/11/24/new-agreement-to-open-the-door-to-next-generation-cell-therapies/

http://www.proactiveinvestors.com.au/companies/news/65781/regeneus-secures-commercial-rights-for-breakthrough-stem-cell-technology-65781.html


My Research Supervision


Areas of supervision

  • Advanced Sensing technologies and biosensors
  • Nanotechnologies towards surface chemistry and stimuli-responsive nanoparticles
  • Point-of-Care diagnostics
  • Microfluidic paper devices
  • Wearable sweat biosensing devices
  • Nanoscale in vivo analysis

Current High Degree Research students

  • Fei Deng (PhD candidate, 2017 S1-
  • Jagjit Kaur (PhD candidate, 2018 T1-), ANSTO top-up scholarship
  • Yi Li (PhD candidate, 2018 T1-)
  • Laicong Qiao (PhD candidate, 2018 T2-)
  • Zijie Luo (PhD candidate, 2018 T2-)
  • Linyang Liu (PhD candidate, 2019 T1-)
  • Mahroo Baharfar (PhD candidate, 2019 T3-)
  • Bitong Li (Master research candidate, 2019 T3-)

Teaching

We are looking for highly motivated postgraduate students pursuing PhD, Master or Honours degree to join the research team. We also welcome the postdoctoral researchers and visiting scholars to explore the opportunities. Once joining our team, the candidates will be collaborating with the research groups of Prof Ewa Goldys (Biophotonics), Prof Nigel Lovell (Biomedical electronics), Prof Margaret Morris (Biology) and Prof Mark Hutchinson (Neuroscience). If you are interested in joining us, please email Dr Guozhen Liu (guozhen.liu@unsw.edu.au) with your CV. 

Postgraduate Scholarship Opportunities

Postdoctoral Fellowship Opportunities

View less

Location

Hilmer Building E10
Level 5, Room 518
UNSW
Sydney NSW 2052

Map reference (Google map)

Contact

029/385-0714