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Journal articles

Kim M; Singh M; Lee BK; Hibbs M; Richardson K; Ellies L; Wintle L; Stuart LM; Wang JY; Voon DC; Blancafort P; Wang J; Kim J; Leedman PJ; Woo AJ, 2022, 'A MYC-ZNF148-ID1/3 regulatory axis modulating cancer stem cell traits in aggressive breast cancer', Oncogenesis, vol. 11, pp. 60, http://dx.doi.org/10.1038/s41389-022-00435-1

Teng L; Feng YC; Guo ST; Wang PL; Qi TF; Yue YM; Wang SX; Zhang SN; Tang CX; La T; Zhang YY; Zhao XH; Gao JN; Wei LY; Zhang D; Wang JY; Shi Y; Liu XY; Li JM; Cao H; Liu T; Thorne RF; Jin L; Shao FM; Zhang XD, 2021, 'The pan-cancer lncRNA PLANE regulates an alternative splicing program to promote cancer pathogenesis', Nature Communications, vol. 12, http://dx.doi.org/10.1038/s41467-021-24099-4

Lan Q; Liu PY; Bell JL; Wang JY; Hüttelmaier S; Zhang XD; Zhang L; Liu T, 2021, 'The emerging roles of RNA m6A methylation and demethylation as critical regulators of tumorigenesis, drug sensitivity, and resistance', Cancer Research, pp. canres.4107.2020 - canres.4107.2020, http://dx.doi.org/10.1158/0008-5472.can-20-4107

Chen J; Nelson C; Wong M; Tee AE; Liu PY; La T; Fletcher JI; Kamili A; Mayoh C; Bartenhagen C; Trahair TN; Xu N; Jayatilleke N; Wong M; Peng H; Atmadibrata B; Cheung BB; Lan Q; Bryan TM; Mestdagh P; Vandesompele J; Combaret V; Boeva V; Wang JY; Janoueix-Lerosey I; Cowley MJ; MacKenzie KL; Dolnikov A; Li J; Polly P; Marshall GM; Reddel RR; Norris MD; Haber M; Fischer M; Zhang XD; Pickett HA; Liu T, 2021, 'Targeted therapy of TERT-rearranged neuroblastoma with BET bromodomain inhibitor and proteasome inhibitor combination therapy', Clinical Cancer Research, vol. 27, pp. 1438 - 1451, http://dx.doi.org/10.1158/1078-0432.CCR-20-3044

La T; Chen S; Guo T; Zhao XH; Teng L; Li D; Carnell M; Zhang YY; Feng YC; Cole N; Brown AC; Zhang D; Dong Q; Wang JY; Cao H; Liu T; Thorne RF; Shao FM; Zhang XD; Jin L, 2021, 'Visualization of endogenous p27 and Ki67 reveals the importance of a c-Myc-driven metabolic switch in promoting survival of quiescent cancer cells', Theranostics, vol. 11, pp. 9605 - 9622, http://dx.doi.org/10.7150/THNO.63763

Hassan N; Yang J; Wang JY, 2020, 'An Improved Protocol for Establishment of AML Patient-Derived Xenograft Models', STAR Protocols, vol. 1, http://dx.doi.org/10.1016/j.xpro.2020.100156

Salik B; Yi H; Hassan N; Santiappillai N; Vick B; Connerty P; Duly A; Trahair T; Woo AJ; Beck D; Liu T; Spiekermann K; Jeremias I; Wang J; Kavallaris M; Haber M; Norris MD; Liebermann DA; D'Andrea RJ; Murriel C; Wang JY, 2020, 'Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia', Cancer Cell, vol. 38, pp. 263 - 278.e6, http://dx.doi.org/10.1016/j.ccell.2020.05.014

Wong M; Sun Y; Xi Z; Milazzo G; Poulos RC; Bartenhagen C; Bell JL; Mayoh C; Ho N; Tee AE; Chen X; Li Y; Ciaccio R; Liu PY; Jiang CC; Lan Q; Jayatilleke N; Cheung BB; Haber M; Norris MD; Zhang XD; Marshall GM; Wang JY; Hüttelmaier S; Fischer M; Wong JWH; Xu H; Perini G; Dong Q; George RE; Liu T, 2019, 'JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma', Nature Communications, vol. 10, pp. 3319, http://dx.doi.org/10.1038/s41467-019-11132-w

Liu PY; Tee AE; Milazzo G; Hannan KM; Maag J; Mondal S; Atmadibrata B; Bartonicek N; Peng H; Ho N; Mayoh C; Ciaccio R; Sun Y; Henderson MJ; Gao J; Everaert C; Hulme AJ; Wong M; Lan Q; Cheung BB; Shi L; Wang JY; Simon T; Fischer M; Zhang XD; Marshall GM; Norris MD; Haber M; Vandesompele J; Li J; Mestdagh P; Hannan RD; Dinger ME; Perini G; Liu T, 2019, 'The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35', Nature Communications, vol. 10, pp. 5026, http://dx.doi.org/10.1038/s41467-019-12971-3

Hassan N; Salik B; Duly A; Wang JY, 2019, 'Rspo-LGR4 Cooperates with HOXA9 to Sustain Self-Renewal in Acute Myeloid Leukemia', Blood, vol. 134, pp. 2669 - 2669, http://dx.doi.org/10.1182/blood-2019-129704

Woo AJ; Patry CAA; Ghamari A; Pregernig G; Yuan D; Zheng K; Piers T; Hibbs M; Li J; Fidalgo M; Wang JY; Lee JH; Leedman PJ; Wang J; Fraenkel E; Cantor AB, 2019, 'Zfp281 (ZBP-99) plays a functionally redundant role with Zfp148 (ZBP-89) during erythroid development', Blood Advances, vol. 3, pp. 2499 - 2511, http://dx.doi.org/10.1182/bloodadvances.2018030551

Gonzales-Aloy E; Connerty P; Salik B; Liu B; Woo AJ; Haber M; Norris MD; Wang J; Wang JY, 2019, 'MiR-101 suppresses the development of MLL-rearranged acute myeloid leukemia', Haematologica, vol. 104, pp. e296 - e299, http://dx.doi.org/10.3324/haematol.2018.209437

Lynch JR; Salik B; Connerty P; Vick B; Leung H; Pijning A; Jeremias I; Spiekermann K; Trahair T; Liu T; Haber M; Norris MD; Woo AJ; Hogg P; Wang J; Wang JY, 2019, 'JMJD1C-mediated metabolic dysregulation contributes to HOXA9-dependent leukemogenesis', Leukemia, vol. 33, pp. 1400 - 1410, http://dx.doi.org/10.1038/s41375-018-0354-z

Voli F; Yi H; Gonzales-Aloy E; Wang JY, 2017, 'Abstract 3906: Targeting a novel G-protein coupled receptor (GPCR) for elimination of leukemia stem cells (LSC)', Cancer Research, vol. 77, pp. 3906 - 3906, http://dx.doi.org/10.1158/1538-7445.am2017-3906

Wong M; Tee AEL; Milazzo G; Bell JL; Poulos RC; Atmadibrata B; Sun Y; Jing D; Ho N; Ling D; Liu PY; Zhang XD; Hüttelmaier S; Wong JWH; Wang J; Polly P; Perini G; Scarlett CJ; Liu T, 2017, 'The histone methyltransferase DOT1L promotes neuroblastoma by regulating gene transcription', Cancer Research, vol. 77, pp. 2522 - 2533, http://dx.doi.org/10.1158/0008-5472.CAN-16-1663

Sun Y; Atmadibrata B; Yu D; Wong M; Liu B; Ho N; Ling D; Tee AE; Wang J; Mungrue IN; Liu PY; Liu T, 2017, 'Upregulation of LYAR induces neuroblastoma cell proliferation and survival', Cell Death and Differentiation, vol. 24, pp. 1645 - 1654, http://dx.doi.org/10.1038/cdd.2017.98

Lynch JR; Yi H; Casolari DA; Voli F; Gonzales-Aloy E; Fung TK; Liu B; Brown A; Liu T; Haber M; Norris MD; Lewis ID; So CWE; D'Andrea RJ; Wang JY, 2016, 'Gaq signaling is required for the maintenance of MLL-AF9-induced acute myeloid leukemia', Leukemia, vol. 30, pp. 1745 - 1748, http://dx.doi.org/10.1038/leu.2016.24

Lynch JR; Wang JY, 2016, 'G protein-coupled receptor signaling in stem cells and cancer', International Journal of Molecular Sciences, vol. 17, http://dx.doi.org/10.3390/ijms17050707

Liu PY; Sokolowski N; Guo ST; Siddiqi F; Atmadibrata B; Telfer TJ; Sun Y; Zhang L; Yu D; Mccarroll J; Liu B; Yang RH; Guo XY; Tee AE; Itoh K; Wang J; Kavallaris M; Haber M; Norris MD; Cheung BB; Byrne JA; Ziegler DS; Marshall GM; Dinger ME; Codd R; Zhang XD; Liu T, 2016, 'The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs', Oncotarget, vol. 7, pp. 79217 - 79232, http://dx.doi.org/10.18632/oncotarget.12640

Dietrich PA; Yang C; Leung HHL; Lynch JR; Gonzales E; Liu B; Haber M; Norris MD; Wang J; Wang JY, 2014, 'GPR84 sustains aberrant β-catenin signaling in leukemic stem cells for maintenance of MLL leukemogenesis', Blood, vol. 124, pp. 3284 - 3294, http://dx.doi.org/10.1182/blood-2013-10-532523

Dietrich PA; Norris MD; Wang JY, 2014, '513: GPR84 is a positive regulator of beta-catenin signalling and is required for the maintenance of MLLAF9-rearranged acute myeloid leukaemia', European Journal of Cancer, vol. 50, pp. S123 - S124, http://dx.doi.org/10.1016/s0959-8049(14)50456-x

Dietrich PA; Norris MD; Wang JY, 2013, 'GPR84, a Proinflammatory Receptor, Sustains Wnt/β-Catenin Signaling In Leukemic Stem Cells For Maintenance Of MLL-AF9-Induced Leukemogenesis', Blood, vol. 122, pp. 3781 - 3781, http://dx.doi.org/10.1182/blood.v122.21.3781.3781

Wang JY; Sprod O; Haber M; Norris MD, 2012, 'Epigenetic Elimination of Mixed-Lineage Leukemia Leukemic Stem Cells by a Potent Small Molecule PRC2 Inhibitor.', Blood, vol. 120, pp. 2456 - 2456, http://dx.doi.org/10.1182/blood.v120.21.2456.2456

Lane SW; Lo celso C; Ragu C; Bullinger L; Wang JY; Sykes SM; Ferraro F; Shterental S; Lin CP; Gilliland DG; Scadden DT; Armstrong SA; Williams DA, 2011, 'Differential niche and Wnt requirements during acute myeloid leukemia progression', Blood, vol. 118, pp. 2849 - 2856, http://dx.doi.org/10.1182/blood-2011-03-345165

Wang Y; Krivtsov AV; Sinha AU; North TE; Goessling W; Feng Z; Zon LI; Armstrong SA, 2010, 'The wnt/β-catenin pathway is required for the development of leukemia stem cells in AML', Science, vol. 327, pp. 1650 - 1653, http://dx.doi.org/10.1126/science.1186624

Wang Y; Krivtsov AV; Sinha AU; North T; Goessling W; Zon LI; Armstrong S, 2009, 'β-Catenin Determines Developmental Stage Specific Transformation by Hox Genes.', Blood, vol. 114, pp. 385 - 385, http://dx.doi.org/10.1182/blood.v114.22.385.385

Wang Y; Armstrong SA, 2008, 'Cancer: Inappropriate Expression of Stem Cell Programs?', Cell Stem Cell, vol. 2, pp. 297 - 299, http://dx.doi.org/10.1016/j.stem.2008.03.014

Wang Y; Krivtsov A; Losyev G; Armstrong SA, 2007, 'Hoxa9+Meis1a Efficiently Transform Hematopoietic Stem Cells but Not Committed Progenitors.', Blood, vol. 110, pp. 3375 - 3375, http://dx.doi.org/10.1182/blood.v110.11.3375.3375

Wang Y; Armstrong SA, 2007, 'Genome-wide SNP analysis in cancer: Leukemia shows the way', CANCER CELL, vol. 11, pp. 308 - 309, http://dx.doi.org/10.1016/j.ccr.2007.03.017

Gao L; Wang J; Wang Y; Andreadis A, 2007, 'SR protein 9G8 modulates splicing of tau exon 10 via its proximal downstream intron, a clustering region for frontotemporal dementia mutations', Molecular and Cellular Neuroscience, vol. 34, pp. 48 - 58, http://dx.doi.org/10.1016/j.mcn.2006.10.004

Krivtsov AV; Twomey D; Feng Z; Stubbs MC; Wang Y; Faber J; Levine JE; Wang J; Hahn WC; Gilliland DG; Golub TR; Armstrong SA, 2006, 'Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9', Nature, vol. 442, pp. 818 - 822, http://dx.doi.org/10.1038/nature04980

Wang Y; Wang J; Gao L; Lafyatis R; Stamm S; Andreadis A, 2005, 'Tau exons 2 and 10, which are misregulated in neurodegenerative diseases, are partly regulated by silencers which bind a SRp30c·SRp55 complex that either recruits or antagonizes htra2β1', Journal of Biological Chemistry, vol. 280, pp. 14230 - 14239, http://dx.doi.org/10.1074/jbc.M413846200

Wang J; Gao Q-S; Wang Y; Lafyatis R; Stamm S; Andreadis A, 2004, 'Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors', Journal of Neurochemistry, vol. 88, pp. 1078 - 1090, http://dx.doi.org/10.1046/j.1471-4159.2003.02232.x

Wang YZ; Slade MB; Gooley AA; Atwell BJ; Williams KL, 2001, 'Cellulose-binding modules from extracellular matrix proteins of Dictyostelium discoideum stalk and sheath', EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 268, pp. 4334 - 4345, http://dx.doi.org/10.1046/j.1432-1327.2001.02354.x


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