Select Publications

Book Chapters

Yik JJ; Crossley M; Quinlan KG R, 2018, 'Genome editing of erythroid cell culture model systems', in Methods in Molecular Biology, pp. 245 - 257, http://dx.doi.org/10.1007/978-1-4939-7428-3_15

Journal articles

Caruana BT; Byrne FL; Knights AJ; Quinlan KG R; Hoehn KL, 2019, 'Characterization of glucose transporter 6 in lipopolysaccharide-induced bone marrow-derived macrophage function', Journal of Immunology, vol. 202, pp. 1826 - 1832, http://dx.doi.org/10.4049/jimmunol.1801063

Martyn GE; Wienert B; Kurita R; Nakamura Y; Quinlan KG R; Crossley M, 2019, 'A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site', Blood, vol. 133, pp. 852 - 856, http://dx.doi.org/10.1182/blood-2018-07-863951

Artuz CM; Knights AJ; Funnell AP W; Gonda TJ; Ravid K; Pearson RC M; Quinlan KG R; Crossley M, 2018, 'Partial reprogramming of heterologous cells by defined factors to generate megakaryocyte lineage-restricted biomolecules', Biotechnology Reports, vol. 20, http://dx.doi.org/10.1016/j.btre.2018.e00285

Wienert B; Martyn GE; Funnell AP W; Quinlan KG R; Crossley M, 2018, 'Wake-up Sleepy Gene: Reactivating Fetal Globin for β-Hemoglobinopathies', Trends in Genetics, vol. 34, pp. 927 - 940, http://dx.doi.org/10.1016/j.tig.2018.09.004

Knights AJ; Vohralik EJ; Hoehn KL; Crossley M; Quinlan KG R, 2018, 'Defining Eosinophil Function in Adiposity and Weight Loss', BioEssays, vol. 40, http://dx.doi.org/10.1002/bies.201800098

Martyn GE; Wienert B; Yang L; Shah M; Norton LJ; Burdach J; Kurita R; Nakamura Y; Pearson RC M; Funnell AP W; Quinlan KG R; Crossley M, 2018, 'Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding', Nature Genetics, vol. 50, pp. 498 - 503, http://dx.doi.org/10.1038/s41588-018-0085-0

Summers MA; Rupasinghe T; Vasiljevski ER; Evesson FJ; Mikulec K; Peacock L; Quinlan KG R; Cooper ST; Roessner U; Stevenson DA; Little DG; Schindeler A, 2018, 'Dietary intervention rescues myopathy associated with neurofibromatosis type 1', Human Molecular Genetics, vol. 27, pp. 577 - 588, http://dx.doi.org/10.1093/hmg/ddx423

McKay MJ; Baldwin JN; Ferreira P; Simic M; Vanicek N; Burns J; Nightingale E; Pourkazemi F; Sman A; Hiller C; Mousavi S; Nicholson L; Rose K; Chard A; Mackey M; Moloney N; Raymond J; Yan AF; Hübscher M; Refshauge K; Wegener C; Lee F; North K; Quinlan K, 2017, 'Normative reference values for strength and flexibility of 1,000 children and adults', Neurology, vol. 88, pp. 36 - 43, http://dx.doi.org/10.1212/WNL.0000000000003466

McKay MJ; Baldwin JN; Ferreira P; Simic M; Vanicek N; Burns J; Nightingale E; Pourkazemi F; Sman A; Hiller C; Mousavi S; Nicholson L; Rose K; Chard A; Mackey M; Moloney N; Raymond J; Yan AF; Hübscher M; Refshauge K; Wegener C; Lee F; North K; Quinlan K, 2017, 'Reference values for developing responsive functional outcome measures across the lifespan', Neurology, vol. 88, pp. 1512 - 1519, http://dx.doi.org/10.1212/WNL.0000000000003847

Hamey JJ; Wienert B; Quinlan KG R; Wilkins MR, 2017, 'METTL21B Is a Novel Human lysine methyltransferase of translation elongation factor 1A: Discovery by CRISPR/Cas9 Knockout', Molecular and Cellular Proteomics, vol. 16, pp. 2229 - 2242, http://dx.doi.org/10.1074/mcp.M116.066308

Norton LJ; Funnell AP W; Burdach J; Wienert B; Kurita R; Nakamura Y; Philipsen S; Pearson RC M; Quinlan KG R; Crossley M, 2017, 'KLF1 directly activates expression of the novel fetal globin repressor ZBTB7A/LRF in erythroid cells.', Blood Adv, vol. 1, pp. 685 - 692, http://dx.doi.org/10.1182/bloodadvances.2016002303

Baldwin JN; McKay MJ; Hiller CE; Nightingale EJ; Moloney N; Burns J; Baldwin J; Chard A; Ferreira P; Yan AF; Hawke F; Lee (née Zheng) F; Mackey M; Mousavi S; Nicholson L; Pourkazemi F; Raymond J; Rose K; Simic M; Sman A; Wegener C; Refshauge KM; Hübscher M; Vanicek N; Quinlan K; North K, 2017, 'Correlates of Perceived Ankle Instability in Healthy Individuals Aged 8 to 101 Years', Archives of Physical Medicine and Rehabilitation, vol. 98, pp. 72 - 79, http://dx.doi.org/10.1016/j.apmr.2016.08.474

Wienert B; Martyn GE; Kurita R; Nakamura Y; Quinlan KG R; Crossley M, 2017, 'KLF1 drives the expression of fetal hemoglobin in British HPFH', Blood, vol. 130, pp. 803 - 807, http://dx.doi.org/10.1182/blood-2017-02-767400

Baldwin JN; McKay MJ; Simic M; Hiller CE; Moloney N; Nightingale EJ; Burns J; Baldwin JN; Chard A; Ferreira P; Fong Yan A; Hiller CE; Lee (nee Zheng) F; Mackey M; Mousavi S; Nicholson L; Nightingale EJ; Pourkazemi F; Raymond J; Rose K; Simic M; Sman A; Wegener C; Refshauge K; Burns J; Moloney N; North K; Hübscher M; Vanicek N; Quinlan K, 2017, 'Self-reported knee pain and disability among healthy individuals: reference data and factors associated with the Knee injury and Osteoarthritis Outcome Score (KOOS) and KOOS-Child', Osteoarthritis and Cartilage, vol. 25, pp. 1282 - 1290, http://dx.doi.org/10.1016/j.joca.2017.03.007

Houweling PJ; Berman YD; Turner N; Quinlan KG R; Seto JT; Yang N; Lek M; MacArthur DG; Cooney G; North KN, 2017, 'Exploring the relationship between α-actinin-3 deficiency and obesity in mice and humans', International Journal of Obesity, vol. 41, pp. 1154 - 1157, http://dx.doi.org/10.1038/ijo.2017.72

Norton LJ; Hallal S; Stout ES; Funnell AP W; Pearson RC M; Crossley M; Quinlan KG R, 2017, 'Direct competition between DNA binding factors highlights the role of Krüppel-like Factor 1 in the erythroid/megakaryocyte switch', Scientific Reports, vol. 7, http://dx.doi.org/10.1038/s41598-017-03289-5

Martyn GE; Quinlan KG R; Crossley M, 2017, 'The regulation of human globin promoters by CCAAT box elements and the recruitment of NF-Y', Biochimica et Biophysica Acta - Gene Regulatory Mechanisms, vol. 1860, pp. 525 - 536, http://dx.doi.org/10.1016/j.bbagrm.2016.10.002

Knights AJ; Yik JJ; Jusoh HM; Norton LJ; Funnell AP W; Pearson RC M; Bell-Anderson KS; Crossley M; Quinlan KG R, 2016, 'Krüppel-like factor 3 (KLF3/BKLF) is required for widespread repression of the inflammatory modulator galectin-3 (Lgals3)', Journal of Biological Chemistry, vol. 291, pp. 16048 - 16058, http://dx.doi.org/10.1074/jbc.M116.715748

Hogarth MW; Garton FC; Houweling PJ; Tukiainen T; Lek M; Macarthur DG; Seto JT; Quinlan KG R; Yang N; Head SI; North KN, 2016, 'Analysis of the ACTN3 heterozygous genotype suggests that α-actinin-3 controls sarcomeric composition and muscle function in a dose-dependent fashion', Human Molecular Genetics, vol. 25, pp. 866 - 877, http://dx.doi.org/10.1093/hmg/ddv613

Lee FX Z; Houweling PJ; North KN; Quinlan KG R, 2016, 'How does α-actinin-3 deficiency alter muscle function? Mechanistic insights into ACTN3, the 'gene for speed'', Biochimica et Biophysica Acta - Molecular Cell Research, vol. 1863, pp. 686 - 693, http://dx.doi.org/10.1016/j.bbamcr.2016.01.013

McKay MJ; Baldwin JN; Ferreira P; Simic M; Vanicek N; Hiller CE; Nightingale EJ; Moloney NA; Quinlan KG; Pourkazemi F; Sman AD; Nicholson LL; Mousavi SJ; Rose K; Raymond J; Mackey MG; Chard A; Hübscher M; Wegener C; Fong Yan A; Refshauge KM; Burns J, 2016, '1000 Norms Project: Protocol of a cross-sectional study cataloging human variation', Physiotherapy (United Kingdom), vol. 102, pp. 50 - 56, http://dx.doi.org/10.1016/j.physio.2014.12.002

Yuen M; Sandaradura SA; Dowling JJ; Kostyukova AS; Moroz N; Quinlan KG; Lehtokari VL; Ravenscroft G; Todd EJ; Ceyhan-Birsoy O; Gokhin DS; Maluenda J; Lek M; Nolent F; Pappas CT; Novak SM; D'Amico A; Malfatti E; Thomas BP; Gabriel SB; Gupta N; Daly MJ; Ilkovski B; Houweling PJ; Davidson AE; Swanson LC; Brownstein CA; Gupta VA; Medne L; Shannon P; Martin N; Bick DP; Flisberg A; Holmberg E; Van Den Bergh P; Lapunzina P; Waddell LB; Sloboda DD; Bertini E; Chitayat D; Telfer WR; Laquerrière A; Gregorio CC; Ottenheijm CA C; Bönnemann CG; Pelin K; Beggs AH; Hayashi YK; Romero NB; Laing NG; Nishino I; Wallgren-Pettersson C; Melki J; Fowler VM; MacArthur DG; North KN; Clarke NF, 2015, 'Erratum: Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy (Journal of Clinical Investigation (2014) 124: 11 (4693-4708) DOI: 10.1172/JCI75199)', Journal of Clinical Investigation, vol. 125, pp. 456 - 457, http://dx.doi.org/10.1172/JCI75199

Summers MA; Quinlan KG; Payne JM; Little DG; North KN; Schindeler A, 2015, 'Skeletal muscle and motor deficits in neurofibromatosis type 1', Journal of Musculoskeletal Neuronal Interactions, vol. 15, pp. 161 - 170

Lim WF; Burdach J; Funnell AP W; Pearson RC M; Quinlan KG R; Crossley M, 2015, 'Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain', Nucleic Acids Research, vol. 44, pp. 3118 - 3130, http://dx.doi.org/10.1093/nar/gkv1380

Wienert B; Funnell AP W; Norton LJ; Pearson RC M; Wilkinson-White LE; Lester K; Vadolas J; Porteus MH; Matthews JM; Quinlan KG R; Crossley M, 2015, 'Editing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin', Nature Communications, vol. 6, http://dx.doi.org/10.1038/ncomms8085

Dewi V; Kwok A; Lee S; Lee MM; Tan YM; Nicholas HR; Isono KI; Wienert B; Mak KS; Knights AJ; Quinlan KG R; Cordwell SJ; Funnell AP W; Pearson RC M; Crossley M, 2015, 'Phosphorylation of krüppel-like factor 3 (KLF3/BKLF) and C-terminal binding protein 2 (CtBP2) by homeodomaininteracting protein kinase 2 (HIPK2) modulates KLF3 DNA binding and activity', Journal of Biological Chemistry, vol. 290, pp. 8591 - 8605, http://dx.doi.org/10.1074/jbc.M115.638338

Head SI; Chan S; Houweling PJ; Quinlan KG R; Murphy R; Wagner S; Friedrich O; North KN, 2015, 'Altered Ca2+ Kinetics Associated with α-Actinin-3 Deficiency May Explain Positive Selection for ACTN3 Null Allele in Human Evolution', PLoS Genetics, vol. 11, http://dx.doi.org/10.1371/journal.pgen.1004862

Thomas KC; Zheng XF; Suarez FG; Raftery JM; Quinlan KG R; Yang N; North KN; Houweling PJ, 2014, 'Evidence based selection of commonly used RT-qPCR reference genes for the analysis of mouse skeletal muscle', PLoS ONE, vol. 9, http://dx.doi.org/10.1371/journal.pone.0088653

Garton FC; Seto JT; Quinlan KG R; Yang N; Houweling PJ; North KN, 2014, 'α-Actinin-3 deficiency alters muscle adaptation in response to denervation and immobilization', Human molecular genetics, vol. 23, pp. 1879 - 1893, http://dx.doi.org/10.1093/hmg/ddt580

Clifton MK; Westman BJ; Thong SY; O'Connell MR; Webster MW; Shepherd NE; Quinlan KG; Crossley M; Blobel GA; Mackay JP, 2014, 'The identification and structure of an N-terminal PR domain show that FOG1 is a member of the PRDM family of proteins', PLoS ONE, vol. 9, http://dx.doi.org/10.1371/journal.pone.0106011

Funnell AP W; Vernimmen D; Lim WF; Mak KS; Wienert B; Martyn GE; Artuz CM; Burdach J; Quinlan KG R; Higgs DR; Whitelaw E; Pearson RC M; Crossley M, 2014, 'Differential regulation of the α-globin locus by Krüppel-like factor 3 in erythroid and non-erythroid cells', BMC Molecular Biology, vol. 15, http://dx.doi.org/10.1186/1471-2199-15-8

Sullivan K; El-hoss J; Quinlan KG R; Deo N; Garton F; Seto JT C; Gdalevitch M; Turner N; Cooney GJ; Kolanczyk M; North KN; Little DG; Schindeler A, 2014, 'NF1 is a critical regulator of muscle development and metabolism', Human Molecular Genetics, vol. 23, pp. 1250 - 1259, http://dx.doi.org/10.1093/hmg/ddt515

Seto JT; Quinlan KG R; Lek M; Zheng XF; Garton F; Macarthur DG; Hogarth MW; Houweling PJ; Gregorevic P; Turner N; Cooney GJ; Yang N; North KN, 2013, 'ACTN3 genotype infuences muscle performance through the regulation of calcineurin signaling', Journal of Clinical Investigation, vol. 123, pp. 4255 - 4263, http://dx.doi.org/10.1172/JCI67691

Nunez N; Clifton MM K; Funnell AP W; Artuz C; Hallal S; Quinlan KG R; Font J; Vandevenne M; Setiyaputra S; Pearson RC M; Mackay JP; Crossley M, 2011, 'The multi-zinc finger protein ZNF217 contacts DNA through a two-finger domain', Journal of Biological Chemistry, vol. 286, pp. 38190 - 38201, http://dx.doi.org/10.1074/jbc.M111.301234

Seto JT; Lek M; Quinlan KG R; Houweling PJ; Zheng XF; Garton F; MacArthur DG; Raftery JM; Garvey SM; Hauser MA; Yang N; Head SI; North KN, 2011, 'Deficiency of α-actinin-3 is associated with increased susceptibility to contraction-induced damage and skeletal muscle remodeling', Human Molecular Genetics, vol. 20, pp. 2914 - 2927, http://dx.doi.org/10.1093/hmg/ddr196

Yang N; Schindeler A; McDonald MM; Seto JT; Houweling PJ; Lek M; Hogarth M; Morse AR; Raftery JM; Balasuriya D; MacArthur DG; Berman Y; Quinlan KG R; Eisman JA; Nguyen TV; Center JR; Prince RL; Wilson SG; Zhu K; Little DG; North KN, 2011, 'α-Actinin-3 deficiency is associated with reduced bone mass in human and mouse', Bone, vol. 49, pp. 790 - 798, http://dx.doi.org/10.1016/j.bone.2011.07.009

Seto JT; Chan S; Turner N; MacArthur DG; Raftery JM; Berman YD; Quinlan KG R; Cooney GJ; Head S; Yang N; North KN, 2011, 'The effect of α-actinin-3 deficiency on muscle aging', Experimental Gerontology, vol. 46, pp. 292 - 302, http://dx.doi.org/10.1016/j.exger.2010.11.006

Lek M; Quinlan KG R; North KN, 2010, 'The evolution of skeletal muscle performance: Gene duplication and divergence of human sarcomeric α-actinins', BioEssays, vol. 32, pp. 17 - 25, http://dx.doi.org/10.1002/bies.200900110

Quinlan KG R; Seto JT; Turner N; Vandebrouck A; Floetenmeyer M; Macarthur DG; Raftery JM; Lek M; Yang N; Parton RG; Cooney GJ; North KN, 2010, 'α-Actinin-3 deficiency results in reduced glycogen phosphorylase activity and altered calcium handling in skeletal muscle', Human Molecular Genetics, vol. 19, pp. 1335 - 1346, http://dx.doi.org/10.1093/hmg/ddq010

Macarthur DG; Seto JT; Chan S; Quinlan KG R; Raftery JM; Turner N; Nicholson MD; Kee AJ; Hardeman EC; Gunning PW; Cooney GJ; Head SI; Yang N; North KN, 2008, 'An Actn3 knockout mouse provides mechanistic insights into the association between α-actinin-3 deficiency and human athletic performance', Human Molecular Genetics, vol. 17, pp. 1076 - 1086, http://dx.doi.org/10.1093/hmg/ddm380

Quinlan KG R; Verger A; Yaswen P; Crossley M, 2007, 'Amplification of zinc finger gene 217 (ZNF217) and cancer: When good fingers go bad', Biochimica et Biophysica Acta - Reviews on Cancer, vol. 1775, pp. 333 - 340, http://dx.doi.org/10.1016/j.bbcan.2007.05.001

MacArthur DG; Seto JT; Raftery JM; Quinlan KG; Huttley GA; Hook JW; Lemckert FA; Kee AJ; Edwards MR; Berman Y; Hardeman EC; Gunning PW; Easteal S; Yang N; North KN, 2007, 'Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans', Nature Genetics, vol. 39, pp. 1261 - 1265, http://dx.doi.org/10.1038/ng2122

Quinlan KG R; Verger A; Kwok A; Lee SH Y; Perdomo J; Nardini M; Bolognesi M; Crossley M, 2006, 'Role of the C-terminal binding protein PXDLS motif binding cleft in protein interactions and transcriptional repression', Molecular and Cellular Biology, vol. 26, pp. 8202 - 8213, http://dx.doi.org/10.1128/MCB.00445-06

Van Vliet J; Crofts LA; Quinlan KG R; Czolij R; Perkins AC; Crossley M, 2006, 'Human KLF17 is a new member of the Sp/KLF family of transcription factors', Genomics, vol. 87, pp. 474 - 482, http://dx.doi.org/10.1016/j.ygeno.2005.12.011

Quinlan KG R; Nardini M; Verger A; Francescato P; Yaswen P; Corda D; Bolognesi M; Crossley M, 2006, 'Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins', Molecular and Cellular Biology, vol. 26, pp. 8159 - 8172, http://dx.doi.org/10.1128/MCB.00680-06

Verger A; Quinlan KG R; Crofts LA; Spanò S; Corda D; Kable EP W; Braet F; Crossley M, 2006, 'Mechanisms directing the nuclear localization of the CtBP family proteins', Molecular and Cellular Biology, vol. 26, pp. 4882 - 4894, http://dx.doi.org/10.1128/MCB.02402-05

Stankovic-Valentin N; Verger A; Deltour-Balerdi S; Quinlan KG R; Crossley M; Leprince D, 2006, 'A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP', FEBS Journal, vol. 273, pp. 2879 - 2890, http://dx.doi.org/10.1111/j.1742-4658.2006.05301.x

Haigh CL; Edwards K; Brown DR, 2005, 'Copper binding is the governing determinant of prion protein turnover', Molecular and Cellular Neuroscience, vol. 30, pp. 186 - 196, http://dx.doi.org/10.1016/j.mcn.2005.07.001

Conference Papers

Kreissl M; Sandaradura SA; Dowling JJ; Kostyukova AS; Moroz N; Quinlan KG; Lehtokari V; Ravenscroft G; Todd EJ; Ceyhan-Birsoy O; Gokhin DS; Maluenda J; Lek M; Nolent F; Pappas CT; Novak SM; D'Amico A; Malfatti E; Thomas BP; Gabriel SB; Gupta N; Daly MJ; Ilkovski B; Houweling PJ; Swanson LC; Brownstein CA; Gupta VA; Medne L; Shannon P; Flisberg A; Holmberg E; Van den Bergh P; Lapunzina P; Waddell LB; Sloboda DD; Bertini E; Chitayat D; Telfer WR; Laquerriere A; Gregorio CC; Ottenheijm CA C; Boennemann CG; Pelin K; Beggs AH; Hayashi YK; Romero NB; Laing NG; Nishino I; Wallgren-Pettersson C; Melki J; Fowler VM; MacArthur DG; North KN; Clarke NF, 2014, 'Mutations in LMOD3 cause severe nemaline myopathy by disrupting thin filament organisation in skeletal muscle', in NEUROMUSCULAR DISORDERS, PERGAMON-ELSEVIER SCIENCE LTD, Berlin, GERMANY, pp. 792 - 793, presented at 19th International Congress of the World-Muscle-Society, Berlin, GERMANY, 07 - 11 October 2014, http://dx.doi.org/10.1016/j.nmd.2014.06.010


Back to profile page