Researcher

Dr Sophie Stocker

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Biography

Sophie Stocker is a Senior Hospital Scientist in the Department of Clinical Pharmacology and Toxicology at St Vincent’s Hospital, Sydney. She is also a conjoint lecturer of the St Vincent’s Clinical School, University of New South Wales. Her research program involves clinical and experimental pharmacology, ethnopharmacology, pharmacogenomics, pharmacometrics and qualitative research on the impact of intrinsic and extrinsic factors on drug...view more

Sophie Stocker is a Senior Hospital Scientist in the Department of Clinical Pharmacology and Toxicology at St Vincent’s Hospital, Sydney. She is also a conjoint lecturer of the St Vincent’s Clinical School, University of New South Wales. Her research program involves clinical and experimental pharmacology, ethnopharmacology, pharmacogenomics, pharmacometrics and qualitative research on the impact of intrinsic and extrinsic factors on drug disposition, efficacy and safety. Her research focuses on understanding variability in response to medicines and how this can be managed to optimise patient care.

On the international front, Dr Sophie Stocker is a founding member of the inaugural Global Pharmacogenomics (PGx) Society, affiliated with the Pharmacogenomics Research Network (PGRN), and is on the Steering Committee for PGx implementation which aims to translate genetic research into routine clinical practice. She is a Co-Principal investigator for an international collaborative GWAS examining ‘The Genetic Determinates of Metformin Pharmacokinetics’.


My Grants

2019    St Vincent’s Clinic Foundation - SVPHS Ladies’ Committee Sister Mary Bernice Research Grant; “Vascular effects of the sodium-glucose cotransporter 2 inhibitor empagliflozin in people with type 2 diabetes and chronic kidney disease”; Day RO, Greenfield JR, Sevastos J, Stocker S, Samocha-Bonet D, Milder T; Award amount: $120,000

2018    St Vincent’s’ Curran Foundation Endowment Award; “Metabolomics of metformin in heart failure”; Carland JE, Stocker SL, Chowdhury G; Award amount: $35,000

2018    St Vincent’s’ Curran Foundation Endowment Award; “Optimising tacrolimus therapy in lung transplant patients”; Stocker SL, Carland JE; Award amount: $30,000

2017-18 The Friends of the Mater Foundation Grant Application; “Pharmacokinetic factors associated with scalp cooling efficacy for docetaxel-containing regimens in cancer patients”; Boyle F, Dear R, Andrews K, Carland JE, Stocker SL; Award amount: $20,000

2017    UNSW Research Infrastructure Scheme; “Installation of a Shimadzu Nexera X2 UHPLC into the Department of Clinical Pharmacology and Toxicology”; Day RO, Carland JE, Stocker SL, Norris RLG, Greenfield JR; Award amount: $78,431

2017    St Vincent’s Clinic Foundation Annual Research Grant; “The safety and pharmacokinetics of metformin in heart failure”; Day RO, Macdonald P, Greenfield J, Graham G, Carland J, Stocker S; Award amount: $30,000

2011    Young Investigator Pilot Award - NIH; “Effect of genetic variation in MATE1 and OCT3 transporters on the pharmacokinetics and pharmacodynamics of metformin in healthy African Americans”; Stocker SL, Dahlin A, Giacomini K; Award amount: $10,000


My Qualifications

PhD, BSc (Hons I)

 


My Awards

2013    American Society for Clinical Pharmacology and Therapeutics, Presidential Trainee Award
2010    UCSF Post-doctoral Travel Grant
2009    Australian Society of Clinical and Experimental Pharmacology and Toxicology Annual Conference, Sydney, Australia. Percy Prize Winner
2008    Dean's award for most outstanding presentation, Faculty Postgraduate Conference, University of Sydney.
2008    Travel grant, Australasian Society of Clinical and Experimental Pharmacology and Toxicology
2007    Australian Pharmaceutical Science Association Conference Pharmaceutical Practice Best Poster
2007    Dean's award for most outstanding presentation, Faculty Postgraduate Conference, University of Sydney.
2007    Travel grant, Australasian Society of Clinical and Experimental Pharmacology and Toxicology
2006 - 2009    Australian Postgraduate Award
2006     "Dorothy Thorp Prize in Science Communication", University of Sydney
2006    Travel grant, Australasian Society of Clinical and Experimental Pharmacology and Toxicology


My Research Activities

Broad Research themes: Quality use of medicines, pharmacotherapy
Specific Research theme: Understanding variability in response to medicines and how this can be managed to optimise patient care
Specific Research expertise: Clinical and experimental aspects of PK, PD, ethnopharmacology, pharmacogenomics, drug metabolism and drug safety in specific ethnic populations and/or special patient populations such as the elderly, people with renal impairment, gout or type II diabetes
 


My Research Supervision


Supervision keywords


Currently supervising

University of New South Wales, Australia (2007-present)
•    Co-supervision of Postgraduate students: Diluk Kannangara (2011-2015), Bishoy Kamel (2014-present), Ana Schteinman (2013-present), Felicity Smith (2014-2018), Gina Chowdury (2016-present), Indy Sandaradura (2016-present), Tamie Milder (2018-present), Ranita Kana (2018-present) 
•    Co-supervision of undergraduate students: Alex Cheng (2015), Joanne Chan (2016), Gina Chowdhury (2016), Crystal Li (2016), Tania Elhage (2016), Vasu Mehndiratta (2017), Kanika X (2017), Rashmi Shingde (2018), Andrew Coulshed (2018), Karson Tam (2018)
•    Tutor for the “Pharmacokinetics” module of the Pharmaceutical Medicine and Drug Development Programs (2008)
•    Mentorship of undergraduate students: Daniel Ng (2006-2007), Jacqueline Anderson (2007-2008), Yewon Chung (2006-2007), Cameron Korb-Wells (2006-2007), Hugo Lee (2007-2008), Praveen Indraratna (2008-2009), Indira Datta (2008-2009), Diluk Kannangara (2009-2010)
•    Mentorship of graduate candidates: Shaun Kumar (2011-2015), Janna Duong (2008-2012)

Notre Dame, Sydney, Australia (2017-present)
•    Supervision of masters students: Alice Minogue (2017), Renee Pope (2017), Alex Stacey (2018)

University of Sydney, Faculty of Pharmacy, Australia (2012-2015)
•    Co-supervision of Honour’s students: Daniel Trajkov (2012), Jenny Shin (2013), Nanty Mulenga (2014), Samson Siu (2015)

University of California, San Francisco, USA (2010-2012)
•    Supervision of Master’s student, Jen Hibma (2011)

University of Sydney, Faculty of Pharmacy, Australia (2006-2009)
•    Undergraduate and postgraduate tutor of the pharmacokinetics course (2007-2009)

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Location

Department of Clinical Pharmacology & Toxicology
St Vincent’s Hospital Sydney
Therapeutics Centre, Level 2 Xavier Building
390 Victoria Street DARLINGHURST NSW 2010

St Vincent's Clinical School, UNSW Medicine, UNSW Sydney

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Contact

02 83822617
02 8382 2724

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