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Journal articles

Nagy Z; Seneviratne JA; Kanikevich M; Chang W; Mayoh C; Venkat P; Du Y; Jiang C; Salib A; Koach J; Carter DR; Mittra R; Liu T; Parker MW; Cheung BB; Marshall GM, 2021, 'An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability', Nature Communications, vol. 12, http://dx.doi.org/10.1038/s41467-021-22143-x

Teng L; Feng YC; Guo ST; Wang PL; Qi TF; Yue YM; Wang SX; Zhang SN; Tang CX; La T; Zhang YY; Zhao XH; Gao JN; Wei LY; Zhang D; Wang JY; Shi Y; Liu XY; Li JM; Cao H; Liu T; Thorne RF; Jin L; Shao FM; Zhang XD, 2021, 'The pan-cancer lncRNA PLANE regulates an alternative splicing program to promote cancer pathogenesis', Nature Communications, vol. 12, http://dx.doi.org/10.1038/s41467-021-24099-4

Cai X; Li JJ; Liu T; Brian O; Li J, 2021, 'Infectious disease mRNA vaccines and a review on epitope prediction for vaccine design.', Brief Funct Genomics, vol. 20, pp. 289 - 303, http://dx.doi.org/10.1093/bfgp/elab027

Cheung BB; Kleynhans A; Mittra R; Kim PY; Holien JK; Nagy Z; Ciampa OC; Seneviratne JA; Mayoh C; Raipuria M; Gadde S; Massudi H; Wong IPL; Tan O; Gong A; Suryano A; Diakiw SM; Liu B; Arndt GM; Liu T; Kumar N; Sangfelt O; Zhu S; Norris MD; Haber M; Carter DR; Parker MW; Marshall GM, 2021, 'A novel combination therapy targeting ubiquitin-specific protease 5 in MYCN-driven neuroblastoma', Oncogene, vol. 40, pp. 2367 - 2381, http://dx.doi.org/10.1038/s41388-021-01712-w

Putra V; Hulme AJ; Tee AE; Sun JQJ; Atmadibrata B; Ho N; Chen J; Gao J; Norris MD; Haber M; Kavallaris M; Henderson MJ; McCarroll J; Trahair T; Liu T; Liu PY, 2021, 'The RNA-helicase DDX21 upregulates CEP55 expression and promotes neuroblastoma', Molecular Oncology, vol. 15, pp. 1162 - 1179, http://dx.doi.org/10.1002/1878-0261.12906

Lan Q; Liu PY; Bell JL; Wang JY; Hüttelmaier S; Zhang XD; Zhang L; Liu T, 2021, 'The emerging roles of RNA m6A methylation and demethylation as critical regulators of tumorigenesis, drug sensitivity, and resistance', Cancer Research, pp. canres.4107.2020 - canres.4107.2020, http://dx.doi.org/10.1158/0008-5472.can-20-4107

Naveed A; Cooper JA; Li R; Hubbard A; Chen J; Liu T; Wilton SD; Fletcher S; Fox AH, 2021, 'NEAT1 polyA-modulating antisense oligonucleotides reveal opposing functions for both long non-coding RNA isoforms in neuroblastoma', Cellular and Molecular Life Sciences, vol. 78, pp. 2213 - 2230, http://dx.doi.org/10.1007/s00018-020-03632-6

Chen J; Nelson C; Wong M; Tee AE; Liu PY; La T; Fletcher JI; Kamili A; Mayoh C; Bartenhagen C; Trahair TN; Xu N; Jayatilleke N; Wong M; Peng H; Atmadibrata B; Cheung BB; Lan Q; Bryan TM; Mestdagh P; Vandesompele J; Combaret V; Boeva V; Wang JY; Janoueix-Lerosey I; Cowley MJ; MacKenzie KL; Dolnikov A; Li J; Polly P; Marshall GM; Reddel RR; Norris MD; Haber M; Fischer M; Zhang XD; Pickett HA; Liu T, 2021, 'Targeted therapy of TERT-rearranged neuroblastoma with BET bromodomain inhibitor and proteasome inhibitor combination therapy', Clinical Cancer Research, vol. 27, pp. 1438 - 1451, http://dx.doi.org/10.1158/1078-0432.CCR-20-3044

La T; Chen S; Guo T; Zhao XH; Teng L; Li D; Carnell M; Zhang YY; Feng YC; Cole N; Brown AC; Zhang D; Dong Q; Wang JY; Cao H; Liu T; Thorne RF; Shao FM; Zhang XD; Jin L, 2021, 'Visualization of endogenous p27 and Ki67 reveals the importance of a c-Myc-driven metabolic switch in promoting survival of quiescent cancer cells', Theranostics, vol. 11, pp. 9605 - 9622, http://dx.doi.org/10.7150/THNO.63763

Tee AE; Ciampa OC; Wong M; Fletcher JI; Kamili A; Chen J; Ho N; Sun Y; Carter DR; Cheung BB; Marshall GM; Liu PY; Liu T, 2020, 'Combination therapy with the CDK7 inhibitor and the tyrosine kinase inhibitor exerts synergistic anticancer effects against MYCN-amplified neuroblastoma', International Journal of Cancer, vol. 147, pp. 1928 - 1938, http://dx.doi.org/10.1002/ijc.32936

Salik B; Yi H; Hassan N; Santiappillai N; Vick B; Connerty P; Duly A; Trahair T; Woo AJ; Beck D; Liu T; Spiekermann K; Jeremias I; Wang J; Kavallaris M; Haber M; Norris MD; Liebermann DA; D'Andrea RJ; Murriel C; Wang JY, 2020, 'Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia', Cancer Cell, vol. 38, pp. 263 - 278.e6, http://dx.doi.org/10.1016/j.ccell.2020.05.014

Bell JL; Hagemann S; Holien JK; Liu T; Nagy Z; Chulte JH; Misiak D; Hüttelmaier S, 2020, 'Identification of rna-binding proteins as targetable putative oncogenes in neuroblastoma', International Journal of Molecular Sciences, vol. 21, pp. 1 - 27, http://dx.doi.org/10.3390/ijms21145098

Bi L; Xie C; Jiao L; Jin S; Hnit SST; Mu Y; Wang Y; Wang Q; Ge G; Wang Y; Zhao X; Shi X; Kang Y; De Souza P; Liu T; Zhou J; Xu L; Dong Q, 2020, 'CPF impedes cell cycle re-entry of quiescent lung cancer cells through transcriptional suppression of FACT and c-MYC', Journal of Cellular and Molecular Medicine, vol. 24, pp. 2229 - 2239, http://dx.doi.org/10.1111/jcmm.14897

Feng YC; Liu XY; Teng L; Ji Q; Wu Y; Li JM; Gao W; Zhang YY; La T; Tabatabaee H; Yan XG; Jamaluddin MFB; Zhang D; Guo ST; Scott RJ; Liu T; Thorne RF; Zhang XD; Jin L, 2020, 'c-Myc inactivation of p53 through the pan-cancer lncRNA MILIP drives cancer pathogenesis', Nature Communications, vol. 11, http://dx.doi.org/10.1038/s41467-020-18735-8

Lan T; Hutvagner G; Lan Q; Liu T; Li J, 2020, 'Sequencing dropout-and-batch effect normalization for single-cell mRNA profiles: a survey and comparative analysis', Briefings in Bioinformatics, http://dx.doi.org/10.1093/bib/bbaa248

Wong M; Sun Y; Xi Z; Milazzo G; Poulos RC; Bartenhagen C; Bell JL; Mayoh C; Ho N; Tee AE; Chen X; Li Y; Ciaccio R; Liu PY; Jiang CC; Lan Q; Jayatilleke N; Cheung BB; Haber M; Norris MD; Zhang XD; Marshall GM; Wang JY; Hüttelmaier S; Fischer M; Wong JWH; Xu H; Perini G; Dong Q; George RE; Liu T, 2019, 'JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma', Nature Communications, vol. 10, pp. 3319, http://dx.doi.org/10.1038/s41467-019-11132-w

Yari H; Jin L; Teng L; Wang Y; Wu Y; Liu GZ; Gao W; Liang J; Xi Y; Feng YC; Zhang C; Zhang YY; Tabatabaee H; La T; Yang RH; Wang FH; Yan XG; Farrelly M; Scott R; Liu T; Thorne RF; Guo ST; Zhang XD, 2019, 'LncRNA REG1CP promotes tumorigenesis through an enhancer complex to recruit FANCJ helicase for REG3A transcription', Nature Communications, vol. 10, http://dx.doi.org/10.1038/s41467-019-13313-z

Liu PY; Tee AE; Milazzo G; Hannan KM; Maag J; Mondal S; Atmadibrata B; Bartonicek N; Peng H; Ho N; Mayoh C; Ciaccio R; Sun Y; Henderson MJ; Gao J; Everaert C; Hulme AJ; Wong M; Lan Q; Cheung BB; Shi L; Wang JY; Simon T; Fischer M; Zhang XD; Marshall GM; Norris MD; Haber M; Vandesompele J; Li J; Mestdagh P; Hannan RD; Dinger ME; Perini G; Liu T, 2019, 'The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35', Nature Communications, vol. 10, pp. 5026, http://dx.doi.org/10.1038/s41467-019-12971-3

Koach J; Holien JK; Massudi H; Carter DR; Ciampa OC; Herath M; Lim T; Seneviratne JA; Milazzo G; Murray JE; McCarroll JA; Liu B; Mayoh C; Keenan B; Stevenson BW; Gorman MA; Bell JL; Doughty L; Hüttelmaier S; Oberthuer A; Fischer M; Gifford AJ; Liu T; Zhang X; Zhu S; Gustafson WC; Haber M; Norris MD; Fletcher JI; Perini G; Parker MW; Cheung BB; Marshall GM, 2019, 'Drugging MYCN oncogenic signaling through the MYCN-PA2G4 binding interface', Cancer Research, vol. 79, pp. 5652 - 5667, http://dx.doi.org/10.1158/0008-5472.CAN-19-1112

Lynch JR; Salik B; Connerty P; Vick B; Leung H; Pijning A; Jeremias I; Spiekermann K; Trahair T; Liu T; Haber M; Norris MD; Woo AJ; Hogg P; Wang J; Wang JY, 2019, 'JMJD1C-mediated metabolic dysregulation contributes to HOXA9-dependent leukemogenesis', Leukemia, vol. 33, pp. 1400 - 1410, http://dx.doi.org/10.1038/s41375-018-0354-z

Lan Q; Liu PY; Haase J; Bell JL; Huttelmaier S; Liu T, 2019, 'The critical role of RNA M6A methylation in cancer', Cancer Research, vol. 79, pp. 1285 - 1292, http://dx.doi.org/10.1158/0008-5472.CAN-18-2965

Wang Q; Liu PY; Liu T; Lan Q, 2019, 'The histone demethylase NO66 induces glioma cell proliferation', Anticancer Research, vol. 39, pp. 6007 - 6014, http://dx.doi.org/10.21873/anticanres.13806

La T; Liu GZ; Farrelly M; Cole N; Feng YC; Zhang YY; Sherwin SK; Yari H; Tabatabaee H; Yan XG; Guo ST; Liu T; Thorne RF; Jin L; Zhang XD, 2018, 'A p53-responsive miRNA network promotes cancer cell quiescence', Cancer Research, vol. 78, pp. 6666 - 6679, http://dx.doi.org/10.1158/0008-5472.CAN-18-1886

Peng H; Zheng Y; Zhao Z; Liu T; Li J, 2018, 'Recognition of CRISPR/Cas9 off-target sites through ensemble learning of uneven mismatch distributions', Bioinformatics, vol. 34, pp. i757 - i765, http://dx.doi.org/10.1093/bioinformatics/bty558

Zhang YY; Tabataba H; Liu XY; Wang JY; Yan XG; Farrelly M; Jiang CC; Guo ST; Liu T; Kao HY; Thorne RF; Zhang XD; Jin L, 2018, 'ACTN4 regulates the stability of RIPK1 in melanoma', Oncogene, vol. 37, pp. 4033 - 4045, http://dx.doi.org/10.1038/s41388-018-0260-x

Ooi CY; Carter DR; Liu B; Mayoh C; Beckers A; Lalwani A; Nagy Z; De Brouwer S; Decaesteker B; Hung TT; Norris MD; Haber M; Liu T; De Preter K; Speleman F; Cheung BB; Marshall GM, 2018, 'Network modeling of microRNA-mRNA interactions in neuroblastoma tumorigenesis identifies miR-204 as a direct inhibitor of MYCN', Cancer Research, vol. 78, pp. 3122 - 3134, http://dx.doi.org/10.1158/0008-5472.CAN-17-3034

Wang YF; Liu F; Sherwin S; Farrelly M; Yan XG; Croft A; Liu T; Jin L; Zhang XD; Jiang CC, 2018, 'Cooperativity of HOXA5 and STAT3 Is Critical for HDAC8 Inhibition-Mediated Transcriptional Activation of PD-L1 in Human Melanoma Cells', Journal of Investigative Dermatology, vol. 138, pp. 922 - 932, http://dx.doi.org/10.1016/j.jid.2017.11.009

Ho N; Peng H; Mayoh C; Liu PY; Atmadibrata B; Marshall GM; Li J; Liu T, 2018, 'Delineation of the frequency and boundary of chromosomal copy number variations in paediatric neuroblastoma', Cell Cycle, vol. 17, pp. 749 - 758, http://dx.doi.org/10.1080/15384101.2017.1421875

Bi L; Xie C; Yao M; Thae Hnit SS; Vignarajan S; Wang Y; Wang Q; Xi Z; Xu H; Li Z; de Souza P; Tee A; Wong M; Liu T; Zhao X; Zhou J; Xu L; Dong Q, 2018, 'The histone chaperone complex FACT promotes proliferative switch of G0 cancer cells', International Journal of Cancer, vol. 145, pp. 164 - 178, http://dx.doi.org/10.1002/ijc.32065

Qiu S; Liu PY; Liu T, 2017, 'Up-regulation of LYAR blocks Myc-induced cell death', Cell Cycle, vol. 16, pp. 1857 - 1858, http://dx.doi.org/10.1080/15384101.2017.1374682

Melaiu O; Mina M; Chierici M; Boldrini R; Jurman G; Romania P; D'Alicandro V; Benedetti MC; Castellano A; Liu T; Furlanello C; Locatelli F; Fruci D, 2017, 'PD-L1 is a therapeutic target of the bromodomain inhibitor JQ1 and, combined with HLA class I, a promising prognostic biomarker in neuroblastoma', Clinical Cancer Research, vol. 23, pp. 4462 - 4472, http://dx.doi.org/10.1158/1078-0432.CCR-16-2601

Wong M; Tee AEL; Milazzo G; Bell JL; Poulos RC; Atmadibrata B; Sun Y; Jing D; Ho N; Ling D; Liu PY; Zhang XD; Hüttelmaier S; Wong JWH; Wang J; Polly P; Perini G; Scarlett CJ; Liu T, 2017, 'The histone methyltransferase DOT1L promotes neuroblastoma by regulating gene transcription', Cancer Research, vol. 77, pp. 2522 - 2533, http://dx.doi.org/10.1158/0008-5472.CAN-16-1663

Tang Y; Cheung BB; Atmadibrata B; Marshall GM; Dinger ME; Liu PY; Liu T, 2017, 'The regulatory role of long noncoding RNAs in cancer', Cancer Letters, vol. 391, pp. 12 - 19, http://dx.doi.org/10.1016/j.canlet.2017.01.010

Jung MS; Russell AJ; Liu B; George J; Liu PY; Liu T; DeFazio A; Bowtell DDL; Oberthuer A; London WB; Fletcher JI; Haber M; Norris MD; Henderson MJ, 2017, 'A Myc activity signature predicts poor clinical outcomes in Myc-associated cancers', Cancer Research, vol. 77, pp. 971 - 981, http://dx.doi.org/10.1158/0008-5472.CAN-15-2906

Peng H; Lan C; Liu Y; Liu T; Blumenstein M; Li J, 2017, 'Chromosome preference of disease genes and vectorization for the prediction of non-coding disease genes', Oncotarget, vol. 8, pp. 78901 - 78916, http://dx.doi.org/10.18632/oncotarget.20481

Sun Y; Atmadibrata B; Yu D; Wong M; Liu B; Ho N; Ling D; Tee AE; Wang J; Mungrue IN; Liu PY; Liu T, 2017, 'Upregulation of LYAR induces neuroblastoma cell proliferation and survival', Cell Death and Differentiation, vol. 24, pp. 1645 - 1654, http://dx.doi.org/10.1038/cdd.2017.98

Liu PY; Atmadibrata B; Mondal S; Tee AE; Liu T, 2016, 'NCYM is upregulated by lncUSMycN and modulates N-Myc expression', International Journal of Oncology, vol. 49, pp. 2464 - 2470, http://dx.doi.org/10.3892/ijo.2016.3730

Lynch JR; Yi H; Casolari DA; Voli F; Gonzales-Aloy E; Fung TK; Liu B; Brown A; Liu T; Haber M; Norris MD; Lewis ID; So CWE; D'Andrea RJ; Wang JY, 2016, 'Gaq signaling is required for the maintenance of MLL-AF9-induced acute myeloid leukemia', Leukemia, vol. 30, pp. 1745 - 1748, http://dx.doi.org/10.1038/leu.2016.24

Guo ST; Chi MN; Yang RH; Guo XY; Zan LK; Wang CY; Xi YF; Jin L; Croft A; Tseng HY; Yan XG; Farrelly M; Wang FH; Lai F; Wang JF; Li YP; Ackland S; Scott R; Agoulnik IU; Hondermarck H; Thorne RF; Liu T; Zhang XD; Jiang CC, 2016, 'INPP4B is an oncogenic regulator in human colon cancer', Oncogene, vol. 35, pp. 3049 - 3061, http://dx.doi.org/10.1038/onc.2015.361

Xi Z; Yao M; Li Y; Xie C; Holst J; Liu T; Cai S; Lao Y; Tan H; Xu HX; Dong Q, 2016, 'Guttiferone K impedes cell cycle re-entry of quiescent prostate cancer cells via stabilization of FBXW7 and subsequent c-MYC degradation', Cell Death and Disease, vol. 7, http://dx.doi.org/10.1038/cddis.2016.123

Shahbazi J; Liu PY; Atmadibrata B; Bradner JE; Marshall GM; Lock RB; Liu T, 2016, 'The bromodomain inhibitor jq1 and the histone deacetylase inhibitor panobinostat synergistically reduce n-myc expression and induce anticancer effects', Clinical Cancer Research, vol. 22, pp. 2534 - 2544, http://dx.doi.org/10.1158/1078-0432.CCR-15-1666

Kim PY; Tan O; Liu B; Trahair T; Liu T; Haber M; Norris MD; Marshall GM; Cheung BB, 2016, 'High TDP43 expression is required for TRIM16-induced inhibition of cancer cell growth and correlated with good prognosis of neuroblastoma and breast cancer patients', Cancer Letters, vol. 374, pp. 315 - 323, http://dx.doi.org/10.1016/j.canlet.2016.02.021

Xue C; Yu DMT; Gherardi S; Koach J; Milazzo G; Gamble L; Liu B; Valli E; Russell AJ; London WB; Liu T; Cheung BB; Marshall GM; Perini G; Haber M; Norris MD, 2016, 'MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4', Oncotarget, vol. 7, pp. 54937 - 54951, http://dx.doi.org/10.18632/oncotarget.10709

Liu PY; Sokolowski N; Guo ST; Siddiqi F; Atmadibrata B; Telfer TJ; Sun Y; Zhang L; Yu D; Mccarroll J; Liu B; Yang RH; Guo XY; Tee AE; Itoh K; Wang J; Kavallaris M; Haber M; Norris MD; Cheung BB; Byrne JA; Ziegler DS; Marshall GM; Dinger ME; Codd R; Zhang XD; Liu T, 2016, 'The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs', Oncotarget, vol. 7, pp. 79217 - 79232, http://dx.doi.org/10.18632/oncotarget.12640

Tee AE; Liu B; Song R; Li J; Pasquier E; Cheung BB; Jiang C; Marshall GM; Haber M; Norris MD; Fletcher JI; Dinger ME; Liu T, 2016, 'The long noncoding RNA MALAT1 promotes tumor-driven angiogenesis by up-regulating pro-angiogenic gene expression', Oncotarget, vol. 7, pp. 8663 - 8675, http://dx.doi.org/10.18632/oncotarget.6675

Sun Y; Bell JL; Carter D; Gherardi S; Poulos RC; Milazzo G; Wong JWH; Al-Awar R; Tee AE; Liu PY; Liu B; Atmadibrata B; Wong M; Trahair T; Zhao Q; Shohet JM; Haupt Y; Schulte JH; Brown PJ; Arrowsmith CH; Vedadi M; MacKenzie KL; Hüttelmaier S; Perini G; Marshall GM; Braithwaite A; Liu T, 2015, 'WDR5 supports an N-myc transcriptional complex that drives a protumorigenic gene expression signature in neuroblastoma', Cancer Research, vol. 75, pp. 5143 - 5154, http://dx.doi.org/10.1158/0008-5472.CAN-15-0423

Carter DR; Murray J; Cheung BB; Gamble L; Koach J; Tsang J; Sutton S; Kalla H; Syed S; Gifford AJ; Issaeva N; Biktasova A; Atmadibrata B; Sun Y; Sokolowski N; Ling D; Kim PY; Webber H; Clark A; Ruhle M; Liu B; Oberthuer A; Fischer M; Byrne J; Saletta F; Thwe LM; Purmal A; Haderski G; Burkhart C; Speleman F; De Preter K; Beckers A; Ziegler DS; Liu T; Gurova KV; Gudkov AV; Norris MD; Haber M; Marshall GM, 2015, 'Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma', Science Translational Medicine, vol. 7, http://dx.doi.org/10.1126/scitranslmed.aab1803

Cheung BB; Tan O; Koach J; Liu B; Shum MSY; Carter DR; Sutton S; Po'uha ST; Chesler L; Haber M; Norris MD; Kavallaris M; Liu T; O'Neill GM; Marshall GM, 2015, 'Thymosin-β4 is a determinant of drug sensitivity for Fenretinide and Vorinostat combination therapy in neuroblastoma', Molecular Oncology, vol. 9, pp. 1484 - 1500, http://dx.doi.org/10.1016/j.molonc.2015.04.005

Bell JL; Turlapati R; Liu T; Schulte JH; Hüttelmaier S, 2015, 'IGF2BP1 harbors prognostic significance by gene gain and diverse expression in neuroblastoma', Journal of Clinical Oncology, vol. 33, pp. 1285 - 1293, http://dx.doi.org/10.1200/JCO.2014.55.9880

Song R; Liu Q; Liu T; Li J, 2015, 'Connecting rules from paired miRNA and mRNA expression data sets of HCV patients to detect both inverse and positive regulatory relationships', BMC Genomics, vol. 16, http://dx.doi.org/10.1186/1471-2164-16-S2-S11


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