Select Publications

Journal articles

Salik B; Yi H; Hassan N; Santiappillai N; Vick B; Connerty P; Duly A; Trahair T; Woo AJ; Beck D; Liu T; Spiekermann K; Jeremias I; Wang J; Kavallaris M; Haber M; Norris MD; Liebermann DA; D'Andrea RJ; Murriel C; Wang JY, 2020, 'Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia', Cancer cell,

Mateos MK; Tulstrup M; Quinn MCJ; Tuckuviene R; Marshall GM; Gupta R; Mayoh C; Wolthers BO; Barbaro PM; Ruud E; Sutton R; Huttunen P; Revesz T; Trakymiene SS; Barbaric D; Tedgård U; Giles JE; Alvaro F; Jonsson OG; Mechinaud F; Saks K; Catchpoole D; Kotecha RS; Dalla-Pozza L; Chenevix-Trench G; Trahair TN; Macgregor S; Schmiegelow K, 2020, 'Genome-wide association meta-analysis of single-nucleotide polymorphisms and symptomatic venous thromboembolism during therapy for acute lymphoblastic leukemia and lymphoma in caucasian children', Cancers, vol. 12,

Mckenna JE; Trahair T, 2020, 'Bronchial carcinoid tumour identified as the cause for recurrent pneumonia in a 10-year-old boy', Journal of Paediatrics and Child Health, vol. 56, pp. 642 - 644,

Berry NK; Scott RJ; Sutton R; Law T; Trahair TN; Dalla-Pozza L; Ritchie P; Barbaric D; Enjeti AK, 2020, 'Enrichment of atypical hyperdiploidy and IKZF1 deletions detected by SNP-microarray in high-risk Australian AIEOP-BFM B-cell acute lymphoblastic leukaemia cohort', Cancer Genetics, vol. 242, pp. 8 - 14,

Xie J; Span M; van Maarseveen E; Langenhorst J; Boddy AV; Sia KCS; Sutton R; Venn N; Punt AM; Tyrrell V; Haber M; Trahair T; Lau L; Marshall GM; Lock RB, 2020, 'Optimization of a clofarabine-based drug combination regimen for the preclinical evaluation of pediatric acute lymphoblastic leukemia', Pediatric Blood and Cancer, vol. 67, pp. e28133,

Ladenstein R; Pö U; Valteau-couanet D; Luksch R; Castel V; Ash S; Laureys G; Brock P; Michon JM; C; Trahair T; Chan GCF; Ruud E; Schroeder H; Beck-popovic M; Schreier G; Loibner H; Ambros P; Holmes K; Castellani MR; Gaze MN; Garaventa A; Pearson ADJ; Lode HN, 2020, 'Investigation of the role of dinutuximab beta-based immunotherapy in the siopen high-risk neuroblastoma 1 trial (HR-NBL1)', Cancers, vol. 12,

Kamili A; Atkinson C; Trahair TN; Fletcher JI, 2020, 'Mouse models of high-risk neuroblastoma', Cancer and Metastasis Reviews,

Kamili A; Gifford AJ; Li N; Mayoh C; Chow S-O; Failes TW; Eden GL; Cadiz R; Xie J; Lukeis RE; Norris MD; Haber M; McCowage GB; Arndt GM; Trahair TN; Fletcher JI, 2020, 'Accelerating development of high-risk neuroblastoma patient-derived xenograft models for preclinical testing and personalised therapy', British Journal of Cancer,

Fordham AM; Xie J; Gifford AJ; Wadham C; Morgan LT; Mould EVA; Fadia M; Zhai L; Massudi H; Ali ZS; Marshall GM; Lukeis RE; Fletcher JI; MacKenzie KL; Trahair TN, 2020, 'CD30 and ALK combination therapy has high therapeutic potency in RANBP2-ALK-rearranged epithelioid inflammatory myofibroblastic sarcoma', British Journal of Cancer,

Lynch JR; Salik B; Connerty P; Vick B; Leung H; Pijning A; Jeremias I; Spiekermann K; Trahair T; Liu T; Haber M; Norris MD; Woo AJ; Hogg P; Wang J; Wang JY, 2019, 'JMJD1C-mediated metabolic dysregulation contributes to HOXA9-dependent leukemogenesis', Leukemia, vol. 33, pp. 1400 - 1410,

Mateos MK; Trahair TN; Mayoh C; Barbaro PM; Sutton R; Revesz T; Barbaric D; Giles JE; Alvaro F; Mechinaud F; Catchpoole D; Kotecha RS; Dalla-Pozza L; Quinn MCJ; MacGregor S; Chenevix-Trench G; Marshall GM, 2019, 'Risk factors for symptomatic venous thromboembolism during therapy for childhood acute lymphoblastic leukemia', Thrombosis Research, vol. 178, pp. 132 - 138,

Boutros R; Catchpoole D; Collins K; Cross S; Downie P; Drinkwater C; Fletcher J; Gottardo N; Hunter S; Kirby M; Ludlow L; MacNish M; Maybury M; Moore A; Morrin H; Purdy S; Revesz T; Saffery R; Strong R; Trahair T; Wood A; Byrne J, 2019, 'The Australian and New Zealand Children's Haematology/Oncology Group Biobanking Network', Biopreservation and Biobanking, vol. 17, pp. 95 - 97,

Gamble LD; Purgato S; Murray J; Xiao L; Yu DMT; Hanssen KM; Giorgi FM; Carter DR; Gifford AJ; Valli E; Milazzo G; Kamili A; Mayoh C; Liu B; Eden G; Sarraf S; Allan S; Giacomo SD; Flemming CL; Russell AJ; Cheung BB; Oberthuer A; London WB; Fischer M; Trahair TN; Fletcher JI; Marshall GM; Ziegler DS; Hogarty MD; Burns MR; Perini G; Norris MD; Haber M, 2019, 'Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma', Science Translational Medicine, vol. 11,

Trahair T; Gifford AJ; Fordham A; Mayoh C; Fadia M; Lukeis R; Wood AC; Valvi S; Walker RD; Blackburn J; Heyer EE; Mercer TR; Barbaric D; Marshall GM; MacKenzie KL, 2019, 'Crizotinib and surgery for long-term disease control in children and adolescents with ALK-positive inflammatory myofibroblastic tumors', JCO Precision Oncology, vol. 3, pp. 1 - 11,

Balzer B; Loo C; Wegner E; Nath C; Lee S; Smith C; Lewis C; Trahair T; Anazodo A, 2018, 'Alectinib is effective, safe and tolerable in an adolescent with stage IVB ALK-rearranged adenocarcinoma of the lung.', Pediatric Hematology-Oncology, pp. 1 - 7,

Tsoli M; Wadham C; Pinese M; Failes T; Joshi S; Mould E; Yin JX; Gayevskiy V; Kumar A; Kaplan W; Ekert PG; Saletta F; Franshaw L; Liu J; Gifford A; Weber MA; Rodriguez M; Cohn RJ; Arndt G; Tyrrell V; Haber M; Trahair T; Marshall GM; McDonald K; Cowley MJ; Ziegler DS, 2018, 'Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer', Cancer Biology and Therapy, vol. 19, pp. 1078 - 1087,

Ladenstein R; Pötschger U; Valteau-Couanet D; Luksch R; Castel V; Yaniv I; Laureys G; Brock P; Michon JM; Owens C; Trahair T; Chan GCF; Ruud E; Schroeder H; Beck Popovic M; Schreier G; Loibner H; Ambros P; Holmes K; Castellani MR; Gaze MN; Garaventa A; Pearson ADJ; Lode HN, 2018, 'Interleukin 2 with anti-GD2 antibody ch14.18/CHO (dinutuximab beta) in patients with high-risk neuroblastoma (HR-NBL1/SIOPEN): a multicentre, randomised, phase 3 trial', The Lancet Oncology, vol. 19, pp. 1617 - 1629,

Vedi A; Mitchell R; Shanmuganathan S; Oswald C; Marshall GM; Trahair T; Sivarajasingam S; Ziegler DS, 2018, 'Increased Survival for Children with Acute Myeloid Leukemia Results from Improved Postrelapse Treatment', Journal of Pediatric Hematology/Oncology, vol. 40, pp. 541 - 547,

Balzer BW; Loo C; Lewis CR; Trahair TN; Anazodo A, 2018, 'Adenocarcinoma of the Lung in Childhood and Adolescence: a systematic review.', J Thorac Oncol., vol. 18, pp. 33035 - 33035,

Matsuno R; Gifford AJ; Fang J; Warren M; Lukeis RE; Trahair T; Sugimoto T; Marachelian A; Asgharzadeh S; Maris JM; Ikegaki N; Shimada H, 2018, 'Rare MYC-amplified Neuroblastoma With Large Cell Histology', Pediatric and Developmental Pathology, vol. 21, pp. 461 - 466,

Vetsch J; Wakefield CE; Robertson EG; Trahair TN; Mateos MK; Grootenhuis M; Marshall GM; Cohn RJ; Fardell JE, 2018, 'Health-related quality of life of survivors of childhood acute lymphoblastic leukemia: a systematic review', Quality of Life Research, vol. 27, pp. 1431 - 1443,

Fletcher JI; Ziegler DS; Trahair TN; Marshall GM; Haber M; Norris MD, 2018, 'Too many targets, not enough patients: Rethinking neuroblastoma clinical trials', Nature Reviews Cancer, vol. 18, pp. 389 - 400,

Sutton R; Venn NC; Law T; Boer JM; Trahair TN; Ng A; Den Boer ML; Dissanayake A; Giles JE; Dalzell P; Mayoh C; Barbaric D; Revesz T; Alvaro F; Pieters R; Haber M; Norris MD; Schrappe M; Dalla Pozza L; Marshall GM, 2018, 'A risk score including microdeletions improves relapse prediction for standard and medium risk precursor B-cell acute lymphoblastic leukaemia in children', British Journal of Haematology, vol. 180, pp. 550 - 562,

Afrin S; Zhang CRC; Meyer C; Stinson CL; Pham T; Bruxner TJC; Venn NC; Trahair TN; Sutton R; Marschalek R; Lynn Fink J; Moore AS, 2018, 'Targeted Next-Generation Sequencing for Detecting MLL Gene Fusions in Leukemia', Molecular Cancer Research, vol. 16, pp. 279 - 285,

Balzer BWR; Loo C; Lewis CR; Trahair TN; Anazodo AC, 2018, 'Adenocarcinoma of the Lung in Childhood and Adolescence: A Systematic Review', Journal of Thoracic Oncology,

Norman M; David C; Wainstein B; Ziegler JB; Cohn R; Mitchell R; O'Brien T; Russell S; Trahair T; Trickett A; Frith K; Gray P, 2017, 'Haematopoietic stem cell transplantation for primary immunodeficiency syndromes: A 5-year single-centre experience', Journal of Paediatrics and Child Health, vol. 53, pp. 988 - 994,

Fardell JE; Vetsch J; Trahair T; Mateos MK; Grootenhuis MA; Touyz LM; Marshall GM; Wakefield CE, 2017, 'Health-related quality of life of children on treatment for acute lymphoblastic leukemia: A systematic review', Pediatric Blood and Cancer, vol. 64,

Trahair T; Sorrentino S; Russell SJ; Sampaio H; Selek L; Plantaz D; Freycon C; Simon T; Kraal K; Beck-Popovic M; Haupt R; Ash S; De Bernardi B, 2017, 'Spinal Canal Involvement in Neuroblastoma', Journal of Pediatrics, vol. 188, pp. 294 - 298,

Ladenstein R; Pötschger U; Pearson ADJ; Brock P; Luksch R; Castel V; Yaniv I; Papadakis V; Laureys G; Malis J; Balwierz W; Ruud E; Kogner P; Schroeder H; de Lacerda AF; Beck-Popovic M; Bician P; Garami M; Trahair T; Canete A; Ambros PF; Holmes K; Gaze M; Schreier G; Garaventa A; Vassal G; Michon J; Valteau-Couanet D, 2017, 'Busulfan and melphalan versus carboplatin, etoposide, and melphalan as high-dose chemotherapy for high-risk neuroblastoma (HR-NBL1/SIOPEN): an international, randomised, multi-arm, open-label, phase 3 trial', The Lancet Oncology, vol. 18, pp. 500 - 514,

Ng M; Forsyth V; Trahair T; Carrington N; Anazodo A, 2017, 'Adolescents, young adults and cancer: What GPs need to know.', Medicine Today, vol. 18(8):, pp. 14 - 22,

Shadur B; Trahair TN; O'Brien T; Russell SJ; Ziegler JB, 2017, 'Desensitisation to liposomal amphotericin B', JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, vol. 5, pp. 181 - 183,

Trahair TN; Lock RB; Sutton R; Sia KCS; Evans K; Richmond J; Law T; Venn NC; Irving JA; Moore S; Nievergall E; Dang P; Heatley SL; White DL; Revesz T, 2016, 'Xenograft-directed personalized therapy for a patient with post-transplant relapse of ALL', Bone Marrow Transplantation, vol. 51, pp. 1279 - 1282,

Chang W; Brohl AS; Patidar R; Sindiri S; Shern JF; Wei JS; Song YK; Yohe ME; Gryder B; Zhang S; Calzone KA; Shivaprasad N; Wen X; Badgett TC; Miettinen M; Hartman KR; League-Pascual JC; Trahair TN; Widemann BC; Merchant MS; Kaplan RN; Lin JC; Khan J, 2016, 'Multidimensional clinomics for precision therapy of children and adolescent young adults with relapsed and refractory cancer: A report from the center for cancer research', Clinical Cancer Research, vol. 22, pp. 3810 - 3820,

Kim PY; Tan O; Liu B; Trahair T; Liu T; Haber M; Norris MD; Marshall GM; Cheung BB, 2016, 'High TDP43 expression is required for TRIM16-induced inhibition of cancer cell growth and correlated with good prognosis of neuroblastoma and breast cancer patients', Cancer Letters, vol. 374, pp. 315 - 323,

Sun Y; Bell JL; Carter D; Gherardi S; Poulos RC; Milazzo G; Wong JWH; Al-Awar R; Tee AE; Liu PY; Liu B; Atmadibrata B; Wong M; Trahair T; Zhao Q; Shohet JM; Haupt Y; Schulte JH; Brown PJ; Arrowsmith CH; Vedadi M; MacKenzie KL; Hüttelmaier S; Perini G; Marshall GM; Braithwaite A; Liu T, 2015, 'WDR5 supports an N-myc transcriptional complex that drives a protumorigenic gene expression signature in neuroblastoma', Cancer Research, vol. 75, pp. 5143 - 5154,

Bartlett A; Goeman E; Vedi A; Mostaghim M; Trahair T; O’Brien TA; Palasanthiran P; McMullan B, 2015, 'A pilot study of a computerized decision support system to detect invasive fungal infection in pediatric hematology/oncology patients', Infection Control and Hospital Epidemiology, vol. 36, pp. 1313 - 1317,

Sutton R; Shaw PJ; Venn NC; Law T; Dissanayake A; Kilo T; Haber M; Norris MD; Fraser C; Alvaro F; Revesz T; Trahair TN; Dalla-Pozza L; Marshall GM; O'Brien TA, 2015, 'Persistent MRD before and after allogeneic BMT predicts relapse in children with acute lymphoblastic leukaemia', British Journal of Haematology, vol. 168, pp. 395 - 404,

Kim PY; Tan O; Diakiw SM; Carter D; Sekerye EO; Wasinger VC; Liu T; Kavallaris M; Norris MD; Haber M; Chesler L; Dolnikov A; Trahair TN; Cheung NK; Marshall GM; Cheung BB, 2014, 'Identification of plasma Complement C3 as a potential biomarker for neuroblastoma using a quantitative proteomic approach', Journal of Proteomics, vol. 96, pp. 1 - 12,

Pasquier E; Trahair T; Kavallaris M; Andre N, 2013, 'Reply: Comment on 'beta-blockers increase response to chemotherapy via direct anti-tumour and anti-angiogenic mechanisms in neuroblastoma'-β- blockers are potent anti-angiogenic and chemo-sensitising agents, rather than cytotoxic drugs', British Journal of Cancer, vol. 109, pp. 2024 - 2025,

Pasquier E; Street J; Pouchy C; Carre M; Gifford AJ; Murray J; Norris MD; Trahair T; Andre N; Kavallaris M, 2013, 'B-blockers increase response to chemotherapy via direct antitumour and anti-angiogenic mechanisms in neuroblastoma', British Journal of Cancer, vol. 108, pp. 2485 - 2494,

Sekyere E; Thomas WD; Keating J; Calao M; Cui HJ; Chen JB; Raif A; Jankowski K; Cheung B; Davies NP NP; Trahair TN; Liu T; Wainwright BJ; Ding HF; Marshall GM, 2013, 'Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation', Oncogene, vol. 32, pp. 3616 - 3626,

Malyukova A; Papa R; O'Brien R; Giles JE; Trahair TN; Pozza LD; Sutton R; Liu T; Haber M; Norris MD; Lock RB; Marshall GM; Giles J, 2013, 'FBXW7 regulates glucocorticoid response in T-cell acute lymphoblastic leukaemia by targeting the glucocorticoid receptor for degradation', Leukemia, vol. 27, pp. 1053 - 1062,

Mateos MK; O'Brien TA; Oswald C; Ziegler DS; Cohn RJ; Russell SJ; Barbaric D; Marshall GM; Trahair TN; Gabriel M, 2013, 'Transplant-related mortality following allogeneic hematopoeitic stem cell transplantation for pediatric acute lymphoblastic leukemia: 25-year retrospective review', Pediatric Blood and Cancer, vol. 60, pp. 1520 - 1527,

Elahi MM; Houng C; Trahair T; Ravindranathan H; Grant PW, 2012, 'Extracorporeal Membrane Oxygenation Support in a Situation of Diagnostic Dilemma', Heart Lung and Circulation, vol. 21, pp. 821 - 823,

Bhadri V; Trahair TN; Lock RB; bhadri , 2012, 'Glucocorticoid resistance in paediatric acute lymphoblastic leukaemia', Journal of Paediatrics and Child Health, vol. 48, pp. 634 - 640,

Marsh DJ; Trahair TN; Kirk EP, 2011, 'Mutant AKT1 in Proteus Syndrome', New England Journal of Medicine, vol. 365, pp. 2141 - 2142,

Bhadri VA; Satharasinghe K; Sugo E; Barbaric D; Trahair TN, 2011, 'Excellent response to dasatinib of childhood Philadelphia positive intracranial acute lymphoblastic leukaemia tumours', British Journal of Haematology, vol. 152, pp. 347 - 349,

Bhadri V; Cowley MJ; Kaplan W; Trahair TN; Lock RB, 2011, 'Evaluation of the NOD/SCID xenograft model for glucocorticoid-regulated gene expression in childhood B-cell precursor acute lymphoblastic leukemia', BMC Genomics, vol. 12, pp. 1 - 13,

Marshall GM; Liu PY; Gherardi S; Scarlett CJ; Bedalov A; Xu N; Iraci N; Valli E; Ling D; Thomas W; Van bekkum M; Sekyere E; Jankowski K; Trahair T; Mackenzie K; Haber M; Norris MD; Biankin AV; Perini G; Liu T, 2011, 'SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability', PLOS Genetics, vol. 7, pp. e1 - e14,

Marshall GM; Gherardi S; Xu N; Neiron Z; Trahair TN; Scarlett CJ; Chang DK; Liu PY; Jankowski K; Iraci N; Haber M; Norris MD; Keating J; Sekyere E; Jonquieres G; Biankin AV; Stossi F; Katzenellenbogen BS; Perini G; Liu T, 2010, 'Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects', Oncogene, vol. 29, pp. 5957 - 5968,

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