Researcher

Dr Wang-Wei Tsai

My Expertise

Dr Tsai leads a research group within the Cytokine and Inflammation Research Program at St Vincent’s Centre for Applied Medical Research (AMR). Her research focus on the biology of a divergent TGFb superfamily cytokine, GDF15. Since joined Prof Sam Breit’s laboratory in 2007, Dr Tsai has elucidated much of the GDF15’s role in central regulation of appetite and obesity resistance. 

 

Keywords

Biography

Dr Tsai was awarded a PhD from the University of Queensland in 2005. This was followed by postdoctoral work at Taiwan’s prestigious Academia Sinica, where she led a study identifying one of the neuroinflammatory mechanisms that causes amyloid plaque accumulation. In 2007, Dr Tsai joined Prof Breit’s team as a postdoctoral scientist in the Inflammation and Cytokine Biology Program at St Vincent’s Centre for Applied Medical Research (AMR)....view more

Dr Tsai was awarded a PhD from the University of Queensland in 2005. This was followed by postdoctoral work at Taiwan’s prestigious Academia Sinica, where she led a study identifying one of the neuroinflammatory mechanisms that causes amyloid plaque accumulation. In 2007, Dr Tsai joined Prof Breit’s team as a postdoctoral scientist in the Inflammation and Cytokine Biology Program at St Vincent’s Centre for Applied Medical Research (AMR). Her research focus has shifted to appetite regulation and metabolism, drawing on her background in neurobiology. She was directly involved in the NHMRC-recognised studies on GDF15/MIC-1 and delineated much of its role in cachexia/appetite/metabolic regulation. Since 2011, Dr Tsai has been a conjoint senior lecturer in the Faculty of Medicine at UNSW and supervises and mentors postgraduate students. In 2016, she received independent research funding as sole CI from the Diabetes Australia Research Trust (DART) looking at GDF15 for treatment of type-2 diabetes, which resulted in identification of the role of GDF15 in the treatment of obesity (selected the best of Int J Obes (Lond) paper of 2018; www.nature.com/collections/hbgddhdbgb.


My Research Activities

Obese animal model, central regulation of metabolism, appetite and inflammation

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Location

Level 8, Lowy Packer Building
405 Liverpool Street, Darlinghurst NSW 2010

Contact

02 8382 4920