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Journal articles

Wang N; Zhang S; Yuan Y; Xu H; Defossa E; Matter H; Besenius M; Derdau V; Dreyer M; Halland N; He KH; Petry S; Podeschwa M; Tennagels N; Jiang X; Yan N, 2022, 'Molecular basis for inhibiting human glucose transporters by exofacial inhibitors', Nature Communications, vol. 13, http://dx.doi.org/10.1038/s41467-022-30326-3

Jiang X, 2022, 'An overview of the Plasmodium falciparum hexose transporter and its therapeutic interventions', Proteins: Structure, Function and Bioinformatics, http://dx.doi.org/10.1002/prot.26351

Peng X; Wang N; Zhu A; Xu H; Li J; Zhou Y; Wang C; Xiao Q; Guo L; Liu F; Jia ZJ; Duan H; Hu J; Yuan W; Geng J; Yan C; Jiang X; Deng D, 2021, 'Structural characterization of the Plasmodium falciparum lactate transporter PfFNT alone and in complex with antimalarial compound MMV007839 reveals its inhibition mechanism', PLoS Biology, vol. 19, http://dx.doi.org/10.1371/journal.pbio.3001386

Wang N; Jiang X; Zhang S; Zhu A; Yuan Y; Xu H; Lei J; Yan C, 2021, 'Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates', Cell, vol. 184, pp. 370 - 383.e13, http://dx.doi.org/10.1016/j.cell.2020.11.043

Huang J; Yuan Y; Zhao N; Pu D; Tang Q; Zhang S; Luo S; Yang X; Wang N; Xiao Y; Zhang T; Liu Z; Sakata-Kato T; Jiang X; Kato N; Yan N; Yin H, 2021, 'Orthosteric–allosteric dual inhibitors of PfHT1 as selective antimalarial agents', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, http://dx.doi.org/10.1073/pnas.2017749118

Jiang X; Yuan Y; Huang J; Zhang S; Luo S; Wang N; Pu D; Zhao N; Tang Q; Hirata K; Yang X; Jiao Y; Sakata-Kato T; Wu JW; Yan C; Kato N; Yin H; Yan N, 2020, 'Structural Basis for Blocking Sugar Uptake into the Malaria Parasite Plasmodium falciparum', Cell, vol. 183, pp. 258 - 268.e12, http://dx.doi.org/10.1016/j.cell.2020.08.015

Gao M; Huang J; Jiang X; Yuan Y; Pang H; Luo S; Wang N; Yao C; Lin Z; Pu D; Zhang S; Sun P; Liu Z; Xiao Y; Wang Q; Hu Z; Yin H, 2020, 'Regulation of aerobic glycolysis to decelerate tumor proliferation by small molecule inhibitors targeting glucose transporters', Protein and Cell, vol. 11, pp. 446 - 451, http://dx.doi.org/10.1007/s13238-020-00725-7

Jiang X; Wu J; Ke M; Zhang S; Yuan Y; Lin JY; Yan N, 2019, 'Engineered XylE as a tool for mechanistic investigation and ligand discovery of the glucose transporters GLUTs', Cell Discov, vol. 5, pp. 14 - 14, http://dx.doi.org/10.1038/s41421-019-0082-1

Jiang X; Xu C; Lei F; Liao M; Wang W; Xu N; Zhang Y; Xie W, 2017, 'MiR-30a targets IL-1α and regulates islet functions as an inflammation buffer and response factor', Scientific Reports, vol. 7, http://dx.doi.org/10.1038/s41598-017-05560-1

Ke M; Yuan Y; Jiang X; Yan N; Gong H, 2017, 'Molecular determinants for the thermodynamic and functional divergence of uniporter GLUT1 and proton symporter XylE', PLoS Comput. Biol., vol. 13, pp. e1005603 - e1005603, http://dx.doi.org/10.1371/journal.pcbi.1005603

TIAN CM; JIANG X; OUYANG XX; ZHANG YO; XIE WD, 2016, 'Berberine enhances antidiabetic effects and attenuates untoward effects of canagliflozin in streptozotocin-induced diabetic mice', Chinese Journal of Natural Medicines, vol. 14, pp. 518 - 526, http://dx.doi.org/10.1016/S1875-5364(16)30061-9

Cui K; Zhang S; Jiang X; Xie W, 2016, 'Novel synergic antidiabetic effects of Astragalus polysaccharides combined with Crataegus flavonoids via improvement of islet function and liver metabolism', Molecular Medicine Reports, vol. 13, pp. 4737 - 4744, http://dx.doi.org/10.3892/mmr.2016.5140

Ouyang X; Jiang X; Gu D; Zhang Y; Kong SK; Jiang C; Xie W, 2016, 'Dysregulated serum miRNA profile and promising biomarkers in dengue-infected patients', International Journal of Medical Sciences, vol. 13, pp. 195 - 205, http://dx.doi.org/10.7150/ijms.13996

Jiang X; Smirnova I; Kasho V; Wu J; Hirata K; Ke M; Pardon E; Steyaert J; Yan N; Kaback HR, 2016, 'Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation', Proc. Natl. Acad. Sci. U.S.A., vol. 113, pp. 12420 - 12425, http://dx.doi.org/10.1073/pnas.1615414113

Zhang S; Ouyang X; Jiang X; Gu D; Lin Y; Kong SK; Xie W, 2015, 'Dysregulated serum microRNA expression profile and potential biomarkers in hepatitis C virus-infected patients', International Journal of Medical Sciences, vol. 12, pp. 590 - 598, http://dx.doi.org/10.7150/ijms.11525

Deng D; Sun P; Yan C; Ke M; Jiang X; Xiong L; Ren W; Hirata K; Yamamoto M; Fan S; Yan N, 2015, 'Molecular basis of ligand recognition and transport by glucose transporters', Nature, vol. 526, pp. 391 - 396, http://dx.doi.org/10.1038/nature14655

Zhang X; Xia M; Li Y; Liu H; Jiang X; Ren W; Wu J; DeCaen P; Yu F; Huang S; He J; Clapham DE; Yan N; Gong H, 2013, 'Analysis of the selectivity filter of the voltage-gated sodium channel Na(v)Rh', Cell Res., vol. 23, pp. 409 - 422, http://dx.doi.org/10.1038/cr.2012.173


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