By Professor Maria Kavallaris

Journal articles

Parker AL; Kavallaris M; McCarroll JA, 2014, 'Microtubules and their role in cellular stress in cancer', Frontiers in Oncology, 4 JUN, pp. 153, http://dx.doi.org/10.3389/fonc.2014.00153

Fife CM; McCarroll JA; Kavallaris M, 2014, 'Movers and shakers: Cell cytoskeleton in cancer metastasis', British Journal of Pharmacology, 171, pp. 5507 - 5523, http://dx.doi.org/10.1111/bph.12704

Vittorio O; Brandl M; Cirillo G; Spizzirri UG; Picci N; Kavallaris M; Iemma F; Hampel S, 2014, 'Novel functional cisplatin carrier based on carbon nanotubes-quercetin nanohybrid induces synergistic anticancer activity against neuroblastoma in vitro', RSC Advances, 4, pp. 31378 - 31384, http://dx.doi.org/10.1039/c4ra03331k

McCarroll JA; Naim S; Sharbeen G; Russia N; Lee J; Kavallaris M; Goldstein D; Phillips PA, 2014, 'Role of pancreatic stellate cells in chemoresistance in pancreatic cancer', Frontiers in Physiology, 5 APR, pp. 141, http://dx.doi.org/10.3389/fphys.2014.00141

Chen X; Cheng X; Soeriyadi AH; Sagnella SM; Lu X; Scott JA; Lowe SB; Kavallaris M; Gooding JJ, 2014, 'Stimuli-responsive functionalized mesoporous silica nanoparticles for drug release in response to various biological stimuli', Biomaterials Science, 2, pp. 121 - 130, http://dx.doi.org/10.1039/c3bm60148j

Sagnella SM; McCarroll JA; Kavallaris M, 2014, 'Drug delivery: Beyond active tumour targeting', Nanomedicine: Nanotechnology, Biology, and Medicine, http://dx.doi.org/10.1016/j.nano.2014.04.012

McCarroll J; Teo J; Boyer C; Goldstein D; Kavallaris M; Phillips PA, 2014, 'Potential applications of nanotechnology for the diagnosis and treatment of pancreatic cancer', Frontiers in Physiology, 5, pp. 1 - 10, http://dx.doi.org/10.3389/fphys.2014.00002

Byrne FL; Yang L; Phillips PA; Hansford LM; Fletcher JI; Ormandy CJ; McCarroll JA; Kavallaris M, 2014, 'RNAi-mediated stathmin suppression reduces lung metastasis in an orthotopic neuroblastoma mouse model', Oncogene, 33, pp. 882 - 890, http://dx.doi.org/10.1038/onc.2013.11

Sevimli S; Sagnella S; Kavallaris M; Bulmus V; Davis TP, 2013, 'Assessment of cholesterol-derived ionic copolymers as potential vectors for gene delivery', Biomacromolecules, 14, pp. 4135 - 4149, http://dx.doi.org/10.1021/bm4013088

Basuki JS; Duong HTT; Macmillan A; Erlich RB; Esser L; Akerfeldt MC; Whan RM; Kavallaris M; Boyer C; Davis TP, 2013, 'Using Fluorescence Lifetime Imaging Microscopy to Monitor Theranostic Nanoparticle Uptake and Intracellular Doxorubicin Release', ACS NANO, 7, pp. 10175 - 10189, http://dx.doi.org/10.1021/nn404407g

Pasquier E; Trahair T; Kavallaris M; Andre N, 2013, 'Reply: Comment on 'beta-blockers increase response to chemotherapy via direct anti-tumour and anti-angiogenic mechanisms in neuroblastoma'-β- blockers are potent anti-angiogenic and chemo-sensitising agents, rather than cytotoxic drugs', British Journal of Cancer, 109, pp. 2024 - 2025, http://dx.doi.org/10.1038/bjc.2013.498

Pasquier E; Street J; Pouchy C; Carre M; Gifford AJ; Murray J; Norris MD; Trahair T; Andre N; Kavallaris M, 2013, 'B-blockers increase response to chemotherapy via direct antitumour and anti-angiogenic mechanisms in neuroblastoma', British Journal of Cancer, 108, pp. 2485 - 2494, http://dx.doi.org/10.1038/bjc.2013.205

Teo J; Erlich RB; Sagnella S; Dwarte T; Davis TP; Kavallaris M; McCarroll J; Boyer C; Duong HTT; Phillips P; Sharbeen G; Goldstein D, 2013, 'Effective delivery of siRNA into cancer cells and tumors using well-defined biodegradable cationic star polymers', Molecular Pharmaceutics, 10, pp. 2435 - 2444, http://dx.doi.org/10.1021/mp400049e

Po'uha ST; Honore S; Braguer D; Kavallaris M, 2013, 'Partial depletion of gamma-actin suppresses microtubule dynamics', Cytoskeleton, 70, pp. 148 - 160, http://dx.doi.org/10.1002/cm.21096

Pasquier E; Tuset MP; Street J; Sinnappan SM; Mackenzie KL; Braguer D; Andre N; Kavallaris M, 2013, 'Concentration- and schedule-dependent effects of chemotherapy on the angiogenic potential and drug sensitivity of vascular endothelial cells', Angiogenesis, 16, pp. 373 - 386, http://dx.doi.org/10.1007/s10456-012-9321-x

Boyer CA; Kavallaris M; Whan R; Macmillan A, 2013, 'Functionalizing biodegradable dextran scaffolds using living radical polymerization: New versatile nanoparticles for the delivery of therapeutic molecules', Molecular Pharmaceutics, 9, pp. 3046 - 3061, http://dx.doi.org/10.1021/mp300144y

Duong HTT; Kamarudin ZM; Erlich RB; Li Y; Jones MJ; Kavallaris M; Boyer CA; Davis TP, 2013, 'Intracellular nitric oxide delivery from stable NO-polymeric nanoparticle carriers', Chemical Communications, 49, pp. 4190 - 4192, http://dx.doi.org/10.1039/c2cc37181b

Bell JL; Malyukova A; Kavallaris M; Marshall GM; Cheung BB, 2013, 'TRIM16 inhibits neuroblastoma cell proliferation through cell cycle regulation and dynamic nuclear localization', Cell Cycle, 12, pp. 889 - 898, http://dx.doi.org/10.4161/cc.23825

Mccarroll JA; Baigude H; Erlich R; Dwarte T; Rana TM; Kayallaris M, 2012, 'Silencing alll-tubulin by RNA interfering nanoparticles in non-small cell lung cancer', CANCER RESEARCH, 72, http://dx.doi.org/10.1158/1538-7445.AM2012-1969

Kan C; Wen VW; Pasquier E; Jankowski K; Chang M; Richards LA; Kavallaris M; Mackenzie K, 2012, 'Endothelial cell dysfunction and cytoskeletal changes associated with repression of p16(INK4a) during immortalization', Oncogene, 31, pp. 4815 - 4827, http://dx.doi.org/10.1038/onc.2011.645

Failes TW; Mitic G; Abdel-halim H; Po'uha ST; Liu M; Hibbs DE; Kavallaris M, 2012, 'Evolution of Resistance to Aurora Kinase B Inhibitors in Leukaemia Cells', PLoS ONE, 7, pp. e30734, http://dx.doi.org/10.1371/journal.pone.0030734

Sevimli S; Sagnella SM; Kavallaris M; Bulmus V; Davis TP, 2012, 'Synthesis, self-assembly and stimuli responsive properties of cholesterol conjugated polymers', Polymer Chemistry, 3, pp. 2057 - 2069, http://dx.doi.org/10.1039/c2py20112g

Cheung BB; Koach J; Tan O; Kim P; Bell J; D'andreti C; Sutton S; Malyukova A; Sekyere E; Norris MD; Haber M; Kavallaris M; Cunningham AM; Proby C; Leigh I; Wilmott J; Cooper C; Halliday GM; Scolyer RA; Marshall GM, 2012, 'The retinoid signalling molecule, TRIM16, is repressed during squamous cell carcinoma skin carcinogenesis in vivo and reduces skin cancer cell migration in vitro', Journal of Pathology, 226, pp. 451 - 462, http://dx.doi.org/10.1002/path.2986

Bell J; Malyukova A; Holien J; Koach J; Parker M; Kavallaris M; Marshall GM; Cheung BB, 2012, 'TRIM16 acts as an E3 ubiquitin ligase and can heterodimerize with other TRIM family members', PLoS One, 7, pp. Article number e37470, http://dx.doi.org/10.1371/journal.pone.0037470

Schofield DJ; Meachem S; West C; Kavallaris M; Callander EJ, 2011, 'A crisis in the making? Education, ageing populations and the future of the medical research workforce', Medical Education, 45, pp. 200 - 207, http://dx.doi.org/10.1111/j.1365-2923.2010.03785.x

Ginu A; McCarroll J; Byrne F; Saricilar S; Kavallaris M; Bulmus V, 2011, 'Block Co-polymer Nanoparticles with Degradable Cross-Linked Core and Low-Molecular-Weight PEG Corona for Anti-tumour Drug Delivery', Journal of Biomaterials Science - Polymer Edition, 22, pp. 1001 - 1022, http://dx.doi.org/10.1163/092050610X497872

Kow SC; McCarroll J; Valade D; Boyer CA; Dwarte T; Davis TP; Kavallaris M; Bulmus V, 2011, 'Dicer-Labile PEG Conjugates for siRNA Delivery', Biomacromolecules, 12, pp. 4301 - 4310, http://dx.doi.org/10.1021/bm201199c

Wong L; Kavallaris M; Bulmus V, 2011, 'Doxorubicin conjugated, crosslinked, PEGylated particles prepared via one-pot thiol-ene modification of a homopolymer scaffold: synthesis and in vitro evaluation', Polymer Chemistry, 2, pp. 385 - 393, http://dx.doi.org/10.1039/c0py00256a

Nakano M; Saldanha R; Gobel A; Kavallaris M; Packer NH, 2011, 'Identification of Glycan Structure Alterations on Cell Membrane Proteins in Desoxyepothilone B Resistant Leukemia Cells', Molecular and Cellular Proteomics, 10, http://dx.doi.org/10.1074/mcp.M111.009001

Pasquier E; Ciccolini J; Carre M; Giacometti S; Fanciullino R; Pouchy C; Montero MP; Serdjebi C; Kavallaris M; Andre N, 2011, 'Propranolol potentiates the anti-angiogenic effects and anti-tumor efficacy of chemotherapy agents: implication in breast cancer treatment.', Oncotarget, 2, pp. 797 - 809

Gan PP; Mccarroll J; Byrne F; Garner J; Kavallaris M, 2011, 'Specific beta-Tubulin Isotypes Can Functionally Enhance or Diminish Epothilone B Sensitivity in Non-Small Cell Lung Cancer Cells', PLoS One, 6, pp. e21717, http://dx.doi.org/10.1371/journal.pone.0021717

Katsetos CD; Draber P; Kavallaris M, 2011, 'Targeting betaIII-tubulin in glioblastoma multiforme: From cell biology and histopathology to cancer therapeutics', Anti-Cancer Agents in Medicinal Chemistry, 11, pp. 719 - 728, http://dx.doi.org/10.2174/187152011797378760

Shum M; Pasquier E; Po'uha ST; O'Neill GM; Chaponnier C; Gunning PW; Kavallaris M, 2011, 'γ-Actin regulates cell migration and modulates the ROCK signaling pathway', The FASEB Journal, 25, pp. 4423 - 4433

Kavallaris M, 2010, 'Erratum: Microtubules and resistance to tubulin-binding agents (Nature Reviews Cancer)', Nature Reviews Cancer, 10, pp. 309, http://dx.doi.org/10.1038/nrc2819

Kavallaris M, 2010, 'Microtubules and resistance to tubulin-binding agents', NATURE REVIEWS CANCER, 10, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000275932700015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Kavallaris M, 2010, 'Microtubules and resistance to tubulin-binding agents', Nature Reviews Cancer, http://dx.doi.org/10.1038/nrc2830

Boyer CA; Priyanto P; Davis TP; Pissuwan D; Bulmus V; Kavallaris M; Teoh WY; Amal R; Carroll M; Woodward R; St pierre T, 2010, 'Anti-fouling magnetic nanoparticles for siRNA delivery', Journal of Materials Chemistry, 20, pp. 255 - 265, http://dx.doi.org/10.1039/b914063h

McCarroll J; Gan PP; Liu M; Kavallaris M, 2010, 'beta III-Tubulin Is a Multifunctional Protein Involved in Drug Sensitivity and Tumorigenesis in Non-Small Cell Lung Cancer', Cancer research, 70, pp. 4995 - 5003, http://dx.doi.org/10.1158/0008-5472.CAN-09-4487

Abraham G; McCaroll J; Byrne F; Saricilar S; Kavallaris M; Bulmus V, 2010, 'Block Co-polymer Nanoparticles with Degradable Cross-Linked Core and Low-Molecular-Weight PEG Corona for Anti-tumour Drug Delivery', Journal of Biomaterials Science - Polymer Edition, 22, pp. 1001 - 1022, http://dx.doi.org/10.1163/092050610X497872

Pasquier E; Sinnappan S; Munoz M; Kavallaris M, 2010, 'ENMD-1198, a New Analogue of 2-Methoxyestradiol, Displays Both Antiangiogenic and Vascular-Disrupting Properties', Molecular Cancer Therapeutics, 9, pp. 1408 - 1418, http://dx.doi.org/10.1158/1535-7163.MCT-09-0894

Po'uha S; Shum MSY; Goebel A; Bernard O; Kavallaris M, 2010, 'LIM-kinase 2, a regulator of actin dynamics, is involved in mitotic spindle integrity and sensitivity to microtubule-destabilizing drugs', Oncogene, 29, pp. 597 - 607, http://dx.doi.org/10.1038/onc.2009.367

Pasquier E; Kavallaris M; Andre N, 2010, 'Metronomic chemotherapy: new rationale for new directions', Nature Reviews Clinical Oncology, 7, pp. 455 - 465, http://dx.doi.org/10.1038/nrclinonc.2010.82

Gan PP; McCarroll JA; Po'uha S; Kamath K; Jordan MA; Kavallaris M, 2010, 'Microtubule Dynamics, Mitotic Arrest, and Apoptosis: Drug-Induced Differential Effects of beta III-Tubulin', Molecular Cancer Therapeutics, 9, pp. 1339 - 1348, http://dx.doi.org/10.1158/1535-7163.MCT-09-0679

Kavallaris M, 2010, 'Microtubules and resistance to tubulin-binding agents', Nature Reviews Cancer, 10, pp. 194 - 204, http://dx.doi.org/10.1038/nrc2803

Liu T; Bell J; Koach J; Malyukova A; Thomas W; Sekyere E; Cunningham A; Norris M; Haber M; Kavallaris M; Cheung B-B; Kim P; Tan O; Marshall G, 2010, 'TRIM16 acts as a tumour suppressor by inhibitory effects on cytoplasmic vimentin and nuclear E2F1 in neuroblastoma cells', Oncogene, 29, pp. 6172 - 6183, http://dx.doi.org/10.1038/onc.2010.340

Liu T, 2009, 'The cyclin-dependent kinase inhibitor, p21WAF1, promotes angiogenesis by repressing gene transcription of thioredoxin-binding protein 2 in cancer cells', Carcinogenesis, 30, pp. 1865 - 1871, http://dx.doi.org/10.1093/carcin/bgp225

Raif A; Marshall GM; Bell J; Koach J; Tan O; D'andreti C; Thomas WD; Sekyere E; Norris MD; Haber M; Kavallaris M; Cheung BB, 2009, 'The estrogen-responsive B box protein (EBBP) restores retinoid sensitivity in retinoid-resistant cancer cells via effects on histone acetylation', Cancer Letters, 277, pp. 82 - 90, http://dx.doi.org/10.1016/j.canlet.2008.11.030

Kavallaris M; Annereau JP; Barret JM, 2008, 'Potential Mechanisms of Resistance to Microtubule Inhibitors', Seminars in Oncology, 35, http://dx.doi.org/10.1053/j.seminoncol.2008.01.006

Ong V; Liem N; Schmid M; Verrills NM; Papa R; Marshall GM; Mackenzie K; Kavallaris M; Lock RB, 2008, 'A role for altered microtubule polymer levels in vincristine resistance of childhood acute lymphoblastic leukemia xenografts', Journal of Pharmacology and Experimental Therapeutics, 324, pp. 434 - 442, http://dx.doi.org/10.1124/jpet.107.128926

Chan YK; Wong TH; Byrne F; Kavallaris M; Bulmus V, 2008, 'Acid-labile core cross-linked micelles for pH-triggered release of antitumor drugs.', Biomacromolecules, 9, pp. 1826 - 1836, http://dx.doi.org/10.1021/bm800043n

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