Select Publications
Journal articles
2004, 'The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition', The Journal of Biological Chemistry, 279, pp. 9298 - 9305
,2003, 'Extracellular acidosis modulates drug block of Kv4.3 currents by flecainide and quinidine', Journal of Cardiovascular Electrophysiology, 14, pp. 641 - 650
,2003, 'Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum', Proceedings of the National Academy of Sciences of the United States of America, 100, pp. 3410 - 3415, http://dx.doi.org/10.1073/pnas.0530278100
,2003, 'Macrophage inhibitory cytokine 1 reduces cell adhesion and induces apoptosis in prostate cancer cells', Cancer research, 63, pp. 5034 - 5040
,2003, 'Macrophage Inhibitory Cytokine-1 in Gestational Tissues and Maternal Serum in Normal and Pre-eclamptic Pregnancy', Placenta, 24, pp. 100 - 106
,2003, 'Macrophage inhibitory cytokine-1: a novel biomarker for p53 pathway activation', Molecular Cancer Therapeutics, 2, pp. 1023 - 1029
,2003, 'Macrophase hihibitory cytokine 1 (MIC-1) in fetal membranes and amniotic fluid from pregnancies with and without preterm labour and premature rupture of membranes', Molecular Human Reproduction, 9, pp. 535 - 540
,2003, 'MIC 1 serum level and genotype: Associations with progress and prognosis of colorectal carcinoma', Clinical Cancer Research, 9, pp. 2642 - 2650
,2003, 'Structure of the HERGK+ channel S5P extracellulal linker: Role of an amphipathic a-helix in C-type inactivation.', Journal of Biochemistry, 278, pp. 42136 - 42148
,2002, 'Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1', Oncogene, 21, pp. 4212 - 4219, http://dx.doi.org/10.1038/sj.onc.1205610
,2002, 'Erratum: A potassium ion channel is involved in cytokine production by activated human macrophages (Clinical and Experimental Immunology (2002) 130 (67-74))', Clinical and Experimental Immunology, 130, pp. 559 - 561, http://dx.doi.org/10.1046/j.1365-2249.2002.02041.x
,2002, 'Extension language automation of embedded system debugging', Automated Software Engineering, 9, pp. 7 - 39, http://dx.doi.org/10.1023/A:1013276002164
,2002, 'A potassium ion channel is involved in cytokine production by activated human macrophages', Clinical and Experimental Immunology, 130, pp. 67 - 74
,2002, 'Activation of Macrophage Promatrix metalloproteinase-9 by Lipopolysaccharide-Associated Proteinases', Journal of Immunology, 168, pp. 2449 - 2455
,2002, 'Antibody-based approach to high-volume genotyping for MIC-1 polymorphism', BioTechniques, 33, pp. 118 - 120
,2002, 'Concentration in plasma of macrophage inhibitory cytokine-1 and risk of cardiovascular events in women: a nested case-control study', Lancet, 359, pp. 2159 - 2163, http://dx.doi.org/10.1016/S0140-6736(02)09093-1
,2002, 'Effects of components of ischemia on the Kv4.3 current stably expressed in chinese hamster ovary cells', Journal of Mol Cell Caridiol, 34, pp. 197 - 207
,2002, 'Recombinant CLIC1 (NCC27) assembles in lipid bilayers via a pH-dependent two-state process to form chloride ion channels with identical characteristics to those observed in Chinese Hamster Ovary cells expressing CLIC1', The Journal of Biological Chemistry, 277, pp. 26003 - 26011
,2001, 'Clozapine and sudden death [10]', Journal of Clinical Psychopharmacology, 21, pp. 630 - 632, http://dx.doi.org/10.1097/00004714-200112000-00023
,2001, 'Differential gene expression of adenosine A1, A2a, A2b, and A3 receptors in the human enteric nervous system', Journal of Comparative Neurology, 439, pp. 46 - 64, http://dx.doi.org/10.1002/cne.1334
,2001, 'Crystal structure of a soluble form of the Intracellular Chloride Ion Channel CLIC1 (NCC27) at 1.4-A resolution', The Journal of Biological Chemistry, pp. 44993 - 45000
,2001, 'Epitope mapping of the transforming growth factor-beta superfamily protein macrophage inhibitory cytokine-1 (MIC-1): indentification of at least five distinct epitope specificities', Biochemistry, pp. 65 - 73
,2001, 'Expression of growth differentiation factor-15/ macrophage inhibitory cytokine-1 (CDF-15/MIC-1) in the perinatal adult and injured rat brain', Journal of Comparative Neurology, pp. 32 - 45
,2001, 'The propeptide of the transforming growth factor beta superfamily member macrophage inhibitory cytokine-1 (MIC-1) Is a multifunctional domain that can facilitate protein folding and secretion', The Journal of Biological Chemistry, pp. 16911 - 16918
,2000, 'The nuclear chloride ion channel NCC27 is involved in regulation of the cell cycle', Journal of Physiology, 529, pp. 541 - 552, http://dx.doi.org/10.1111/j.1469-7793.2000.00541.x
,2000, 'Analysis of dendritic cell populations using a revised histological staging of morphoea', British Journal of Dermatology, 143, pp. 1183 - 1192, http://dx.doi.org/10.1046/j.1365-2133.2000.03886.x
,2000, 'The transforming growth factor-β superfamily cytokine macrophage inhibitory cytokine-1 is present in high concentrations in the serum of pregnant women', Journal of Clinical Endocrinology and Metabolism, 85, pp. 4781 - 4788, http://dx.doi.org/10.1210/jc.85.12.4781
,2000, 'Intracellular Ion Channel NCC27 Moves between a Soluble and a Transmembrane State', Biochemical Society Transactions, 28, pp. A471 - A471, http://dx.doi.org/10.1042/bst028a471c
,2000, 'Expression of a TGF-β superfamily protein, macrophage inhibitory cytokine-1, in the yeast Pichia pastoris', Gene, 254, pp. 67 - 76, http://dx.doi.org/10.1016/S0378-1119(00)00295-X
,2000, 'The heart of psychotropic drug therapy.', Lancet, 355, pp. 1825, http://dx.doi.org/10.1016/S0140-6736(05)73083-X
,2000, 'Comparative effects of azimilide and ambasilide on the human ether-a-go-go-related gene (HERG) potassium channel', Cardiovascular Research, pp. 44 - 58
,2000, 'Functional characterization of the NCC27 nuclear protein in stable transfected CHO-K1 cells', Federation of American Societies for Experimantal Biology Journal, 14, pp. 1171 - 1178
,2000, 'Hyperkalaemia and acidosis modify HERG channel biophysical properties and antagonise inhibition by sotalol', Heart, Lung and Circulation, 9, pp. A131 - A131, http://dx.doi.org/10.1046/j.1443-9506.2000.07650.x
,2000, 'Inhibiton of HERG potassium channels by the antimalarial agent halofantrine', British Journal of Pharmacology, 130, pp. 1967 - 1975
,2000, 'Potent blockade by quinidine of the Kv4.3 current: Significance with regard to treatment of the brugada syndrome', Heart, Lung and Circulation, 9, pp. A92 - A92, http://dx.doi.org/10.1046/j.1443-9506.2000.06115.x
,2000, 'The antipsychotic agents thioridazine, chlorpromazine and clozapine block the human-ether-a-go-go-related gene (HERG) potassium channel: Cellular mechanism for proarrhythmia', Heart, Lung and Circulation, 9, pp. A109 - A109, http://dx.doi.org/10.1046/j.1443-9506.2000.06796.x
,2000, 'The Propeptide of macrophage inhibitory cytokine (MIC-1) , a TGF-b superfamily member, act as a quality control determinant for correctly folded MIC-1.', European Molecular Biology Organization, 19, pp. 2212 - 2220
,1999, 'Effects of tetrabutylhydroperoxide on hepatocyte ion channels', Cellular Physiology and Biochemistry, 9, pp. 133 - 138, http://dx.doi.org/10.1159/000016310
,1999, 'Blockade by N-3 polyunsaturated fatty acid of the Kv4.3 current stably expressed in Chinese Hamster ovary cells', British Journal of Pharmacology, 127, pp. 941 - 948
,1999, 'Inhibition of HERG channels stably expressed in a mammalian cell line by the antianginal agent perhexiline maleate.', British Journal of Pharmacology, 127, pp. 243 - 251
,1999, 'Inhibition of the human ether-a-go-go-related gene (HERG) potassium channel by cisapride: affinity for open and inactivated states', British Journal of Pharmacology, 128, pp. 444 - 450
,1999, 'MIC-1 is a novel TGF-beta superfamily cytokine associated with macrophage activation', Journal of Leukocyte Biology, pp. 2 - 5
,1999, 'Screening procedure for Pichia pastoris clones containing multiple copy gene inserts', BioTechniques, pp. 1042 - 1044
,1998, 'Alternative hypothesis for efficacy of macrolides in acute coronary syndromes', Lancet, 351, pp. 1858 - 1859, http://dx.doi.org/10.1016/S0140-6736(05)78804-8
,1998, 'Regulation of ion channels in rat hepatocytes', Pflugers Archiv European Journal of Physiology, 435, pp. 203 - 210, http://dx.doi.org/10.1007/s004240050502
,1997, 'MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-Beta superfamily cluster.', Proceedings of the National Academy of Sciences of the United States of America, pp. 11514 - 11519
,1997, 'Molecular cloning and expression of a chloride ion channel of cell nuclei.', The Journal of Biological Chemistry, pp. 12575 - 12582
,1997, 'Scleroderma Lung Disease', Biodrugs, pp. 185 - 192
,1996, 'Both in vitro and in vivo irradiation are associated with induction of macrophage derived fibroblast growth factors', Clinical and Experimental Immunology, 103, pp. 67 - 73
,1995, 'Electrophysiological effects of progesterone on hepatocytes', Biochimica et Biophysica Acta - Molecular Cell Research, 1266, pp. 186 - 190, http://dx.doi.org/10.1016/0167-4889(94)00236-8
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