By Professor Stuart Graham Tangye

Journal articles

Lévy R; Langlais D; Béziat V; Rapaport F; Rao G; Lazarov T; Bourgey M; Zhou YJ; Briand C; Moriya K; Ailal F; Avery DT; Markle J; Lim AI; Ogishi M; Yang R; Pelham S; Emam M; Migaud M; Deswarte C; Habib T; Saraiva LR; Moussa EA; Guennoun A; Boisson B; Belkaya S; Martinez-Barricarte R; Rosain J; Belkadi A; Breton S; Payne K; Benhsaien I; Plebani A; Lougaris V; Di Santo JP; Neven B; Abel L; Ma CS; Bousfiha AA; Marr N; Bustamante J; Liu K; Gros P; Geissmann F; Tangye SG; Casanova JL; Puel A, 2021, 'Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to multiple infectious agents', Journal of Clinical Investigation, 131, http://dx.doi.org/10.1172/JCI150143

Ogishi M; Yang R; Aytekin C; Langlais D; Bourgey M; Khan T; Ali FA; Rahman M; Delmonte OM; Chrabieh M; Zhang P; Gruber C; Pelham SJ; Spaan AN; Rosain J; Lei WT; Drutman S; Hellmann MD; Callahan MK; Adamow M; Wong P; Wolchok JD; Rao G; Ma CS; Nakajima Y; Yaguchi T; Chamoto K; Williams SC; Emile JF; Rozenberg F; Glickman MS; Rapaport F; Kerner G; Allington G; Tezcan I; Cagdas D; Hosnut FO; Dogu F; Ikinciogullari A; Rao VK; Kainulainen L; Béziat V; Bustamante J; Vilarinho S; Lifton RP; Boisson B; Abel L; Bogunovic D; Marr N; Notarangelo LD; Tangye SG; Honjo T; Gros P; Boisson-Dupuis S; Casanova JL, 2021, 'Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child', Nature Medicine, 27, pp. 1646 - 1654, http://dx.doi.org/10.1038/s41591-021-01388-5

Hewavisenti RV; Ferguson AL; Gasparini G; Ohashi T; Braun A; Watkins TS; Miles JJ; Elliott M; Sierro F; Feng CG; Britton WJ; Gebhardt T; Tangye S; Palendira U, 2021, 'Tissue-resident regulatory T cells accumulate at human barrier lymphoid organs', Immunology and Cell Biology, 99, pp. 894 - 906, http://dx.doi.org/10.1111/imcb.12481

Bastard P; Gervais A; Voyer TL; Rosain J; Philippot Q; Manry J; Michailidis E; Hoffmann HH; Eto S; Garcia-Prat M; Bizien L; Parra-Martínez A; Yang R; Haljasmägi L; Migaud M; Särekannu K; Maslovskaja J; De Prost N; Tandjaoui-Lambiotte Y; Luyt CE; Amador-Borrero B; Gaudet A; Poissy J; Morel P; Richard P; Cognasse F; Troya J; Trouillet-Assant S; Belot A; Saker K; Garçon P; Rivière JG; Lagier JC; Gentile S; Rosen LB; Shaw E; Morio T; Tanaka J; Dalmau D; Tharaux PL; Sene D; Stepanian A; Megarbane B; Triantafyllia V; Fekkar A; Heath JR; Franco JL; Anaya JM; Solé-Violán J; Imberti L; Biondi A; Bonfanti P; Castagnoli R; Delmonte OM; Zhang Y; Snow AL; Holland SM; Biggs CM; Moncada-Vélez M; Arias AA; Lorenzo L; Boucherit S; Coulibaly B; Anglicheau D; Planas AM; Haerynck F; Duvlis S; Nussbaum RL; Ozcelik T; Keles S; Bousfiha AA; El Bakkouri J; Ramirez-Santana C; Paul S; Pan-Hammarström Q; Hammarström L; Dupont A; Kurolap A; Metz CN; Aiuti A; Casari G; Lampasona V; Ciceri F; Barreiros LA; Dominguez-Garrido E; Vidigal M; Zatz M; Van De Beek D; Sahanic S; Tancevski I; Stepanovskyy Y; Boyarchuk O; Nukui Y; Tsumura M; Vidaur L; Tangye SG; Burrel S; Duffy D; Quintana-Murci L; Klocperk A, 2021, 'Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths', Science Immunology, 6, http://dx.doi.org/10.1126/sciimmunol.abl4340

Asano T; Khourieh J; Zhang P; Rapaport F; Spaan AN; Li J; Lei WT; Pelham SJ; Hum D; Chrabieh M; Han JE; Guérin A; Mackie J; Gupta S; Saikia B; Baghdadi JEI; Fadil I; Bousfiha A; Habib T; Marr N; Ganeshanandan L; Peake J; Droney L; Williams A; Celmeli F; Hatipoglu N; Ozcelik T; Picard C; Abel L; Tangye SG; Boisson-Dupuis S; Zhang Q; Puel A; Béziat V; Casanova JL; Boisson B, 2021, 'Human stat3 variants underlie autosomal dominant hyper-igesyndromebynegativedominance', Journal of Experimental Medicine, 218, http://dx.doi.org/10.1084/jem.20202592

Eisenbarth SC; Baumjohann D; Craft J; Fazilleau N; Ma CS; Tangye SG; Vinuesa CG; Linterman MA, 2021, 'CD4⁺ T cells that help B cells – a proposal for uniform nomenclature', Trends in Immunology, 42, pp. 658 - 669, http://dx.doi.org/10.1016/j.it.2021.06.003

Cagdas D; Mayr D; Baris S; Worley L; Langley DB; Metin A; Aytekin ES; Atan R; Kasap N; Bal SK; Dmytrus J; Heredia RJ; Karasu G; Torun SH; Toyran M; Karakoc-Aydiner E; Christ D; Kuskonmaz B; Uçkan-Çetinkaya D; Uner A; Oberndorfer F; Schiefer AI; Uzel G; Deenick EK; Keller B; Warnatz K; Neven B; Durandy A; Sanal O; Ma CS; Özen A; Stepensky P; Tezcan I; Boztug K; Tangye SG, 2021, 'Genomic Spectrum and Phenotypic Heterogeneity of Human IL-21 Receptor Deficiency', Journal of Clinical Immunology, 41, pp. 1272 - 1290, http://dx.doi.org/10.1007/s10875-021-01031-5

Bucciol G; Tousseyn T; Jansen K; Casteels I; Tangye SG; Breuer J; Brown JR; Wollants E; Van Ranst M; Moens L; Mekahli D; Meyts I, 2021, 'Hematopoietic Stem Cell Transplantation Cures Chronic Aichi Virus Infection in a Patient with X-linked Agammaglobulinemia', Journal of Clinical Immunology, 41, pp. 1403 - 1405, http://dx.doi.org/10.1007/s10875-021-01056-w

Béziat V; Rapaport F; Hu J; Titeux M; Bonnet des Claustres M; Bourgey M; Griffin H; Bandet É; Ma CS; Sherkat R; Rokni-Zadeh H; Louis DM; Changi-Ashtiani M; Delmonte OM; Fukushima T; Habib T; Guennoun A; Khan T; Bender N; Rahman M; About F; Yang R; Rao G; Rouzaud C; Li J; Shearer D; Balogh K; Al Ali F; Ata M; Dabiri S; Momenilandi M; Nammour J; Alyanakian MA; Leruez-Ville M; Guenat D; Materna M; Marcot L; Vladikine N; Soret C; Vahidnezhad H; Youssefian L; Saeidian AH; Uitto J; Catherinot É; Navabi SS; Zarhrate M; Woodley DT; Jeljeli M; Abraham T; Belkaya S; Lorenzo L; Rosain J; Bayat M; Lanternier F; Lortholary O; Zakavi F; Gros P; Orth G; Abel L; Prétet JL; Fraitag S; Jouanguy E; Davis MM; Tangye SG; Notarangelo LD; Marr N; Waterboer T; Langlais D; Doorbar J; Hovnanian A; Christensen N; Bossuyt X; Shahrooei M; Casanova JL, 2021, 'Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy', Cell, 184, pp. 3812 - 3828.e30, http://dx.doi.org/10.1016/j.cell.2021.06.004

Yang R; Weisshaar M; Mele F; Benhsaien I; Dorgham K; Han J; Croft CA; Notarbartolo S; Rosain J; Bastard P; Puel A; Fleckenstein B; Glimcher LH; Di Santo JP; Ma CS; Gorochov G; Bousfiha A; Abel L; Tangye SG; Casanova JL; Bustamante J; Sallusto F, 2021, 'High Th2 cytokine levels and upper airway inflammation in human inherited T-bet deficiency', Journal of Experimental Medicine, 218, http://dx.doi.org/10.1084/jem.20202726

Sancho-Shimizu V; Brodin P; Cobat A; Biggs CM; Toubiana J; Lucas CL; Henrickson SE; Belot A; Tangye SG; Milner JD; Levin M; Abel L; Bogunovic D; Casanova JL; Zhang SY; Haddad E; Beland K; Pujol A; Schlüter A; Planas-Serra L; Aguilera-Albesa S; Valencia-Ramos J; Rodríguez-Palmero A; Gut M; Rivière JG; Colobran R; Soler-Palacin P; Rodriguez-Gallego C; de Diego RP; Flores C; Alsina L; Blazquez-Gamero D; Jordan I; Keles S; Emiroglu M; Akcan OM; Alkan G; Aytekin SE; Gul Y; Tüter Öz ŞK; Bozdemir SE; Bayhan GI; Yüksek SK; Parlakay AÖ; Gülhan B; Yahşi A; Kilic AO; Karbuz A; Erdeniz EH; Özkan EA; Orbak Z; Aydemir Ş; Celik JB; Kandemir B; Aytekin G; Kapakli H; Yarar V; Yosunkaya A; Vatansev H; Aytekin C; Torun SH; Nepesov S; Coskuner T; Sözeri B; Demirkol YK; Kasapcopur O; Yıldız M; Sevketoglu E; Hatipoğlu N; Özçelik T; Yesilbas O; Gayretli Aydin ZG; Sediva A; Klocperk A; Bloomfield M; Meyts I; Delafontaine S; Haerynck F; Hoste L; Shahrooei M; Marque L; Neves JF; Novelli G; Novelli A; Aiuti A; Casari G; Bousfiha AA; Almuhsen SZ; Sobh A; Gagro A; Bajolle F; Bonnet D; Lebon P; Lei W; Lee D; Seeleuthner Y; Zhang P; Maglorius M; Philippot Q; Pelham S, 2021, 'SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease?', Journal of Experimental Medicine, 218, http://dx.doi.org/10.1084/jem.20210446

Della Mina E; Guérin A; Tangye SG, 2021, 'Molecular requirements for human lymphopoiesis as defined by inborn errors of immunity', Stem Cells, 39, pp. 389 - 402, http://dx.doi.org/10.1002/stem.3327

Tangye SG; Al-Herz W; Bousfiha A; Cunningham-Rundles C; Franco JL; Holland SM; Klein C; Morio T; Oksenhendler E; Picard C; Puel A; Puck J; Seppänen MRJ; Somech R; Su HC; Sullivan KE; Torgerson TR; Meyts I, 2021, 'The Ever-Increasing Array of Novel Inborn Errors of Immunity: an Interim Update by the IUIS Committee', Journal of Clinical Immunology, 41, pp. 666 - 679, http://dx.doi.org/10.1007/s10875-021-00980-1

Meyts I; Bucciol G; Quinti I; Neven B; Fischer A; Seoane E; Lopez-Granados E; Gianelli C; Robles-Marhuenda A; Jeandel PY; Paillard C; Sankaran VG; Demirdag YY; Lougaris V; Aiuti A; Plebani A; Milito C; Dalm VA; Guevara-Hoyer K; Sánchez-Ramón S; Bezrodnik L; Barzaghi F; Gonzalez-Granado LI; Hayman GR; Uzel G; Mendonça LO; Agostini C; Spadaro G; Badolato R; Soresina A; Vermeulen F; Bosteels C; Lambrecht BN; Keller M; Mustillo PJ; Abraham RS; Gupta S; Ozen A; Karakoc-Aydiner E; Baris S; Freeman AF; Yamazaki-Nakashimada M; Scheffler-Mendoza S; Espinosa-Padilla S; Gennery AR; Jolles S; Espinosa Y; Poli MC; Fieschi C; Hauck F; Cunningham-Rundles C; Mahlaoui N; Warnatz K; Sullivan KE; Tangye SG, 2021, 'Coronavirus disease 2019 in patients with inborn errors of immunity: An international study', Journal of Allergy and Clinical Immunology, 147, pp. 520 - 531, http://dx.doi.org/10.1016/j.jaci.2020.09.010

Pillay BA; Fusaro M; Gray PE; Statham AL; Burnett L; Bezrodnik L; Kane A; Tong W; Abdo C; Winter S; Chevalier S; Levy R; Masson C; Schmitt Y; Bole C; Malphettes M; Macintyre E; de Villartay JP; Ziegler JB; Smart JM; Peake J; Aghamohammadi A; Hammarström L; Abolhassani H; Picard C; Fischer A; Latour S; Neven B; Tangye SG; Ma CS, 2021, 'Somatic reversion of pathogenic DOCK8 variants alters lymphocyte differentiation and function to effectively cure DOCK8 deficiency', Journal of Clinical Investigation, 131, http://dx.doi.org/10.1172/JCI142434

Bigas A; Zanoni I; Hepworth MR; Eisenbarth SC; Masters SL; Kipnis J; Vinuesa CG; Good-Jacobson KL; Tangye SG; Yamazaki S; Hivroz C; Wojno ET; Shulman Z; Colonna M, 2021, 'JEM career launchpad', Journal of Experimental Medicine, 218, http://dx.doi.org/10.1084/jem.20202509

Nguyen T; Deenick EK; Tangye SG, 2021, 'Phosphatidylinositol 3-kinase signaling and immune regulation: insights into disease pathogenesis and clinical implications', Expert Review of Clinical Immunology, 17, pp. 905 - 914, http://dx.doi.org/10.1080/1744666X.2021.1945443

Keller B; Strohmeier V; Harder I; Unger S; Payne KJ; Andrieux G; Boerries M; Felixberger PT; Landry JJM; Nieters A; Rensing-Ehl A; Salzer U; Frede N; Usadel S; Elling R; Speckmann C; Hainmann I; Ralph E; Gilmour K; Wentink MWJ; van der Burg M; Kuehn HS; Rosenzweig SD; Kölsch U; von Bernuth H; Kaiser-Labusch P; Gothe F; Hambleton S; Vlagea AD; Garcia AG; Alsina L; Markelj G; Avcin T; Vasconcelos J; Guedes M; Ding JY; Ku CL; Shadur B; Avery DT; Venhoff N; Thiel J; Becker H; Erazo-Borrás L; Trujillo-Vargas CM; Franco JL; Fieschi C; Okada S; Gray PE; Uzel G; Casanova JL; Fliegauf M; Grimbacher B; Eibel H; Ehl S; Voll RE; Rizzi M; Stepensky P; Benes V; Ma CS; Bossen C; Tangye SG; Warnatz K, 2021, 'The expansion of human T-bet^highCD21^low B cells is T cell dependent', Science Immunology, 6, http://dx.doi.org/10.1126/sciimmunol.abh0891

Yang R; Mele F; Worley L; Langlais D; Rosain J; Benhsaien I; Elarabi H; Croft CA; Doisne JM; Zhang P; Weisshaar M; Jarrossay D; Latorre D; Shen Y; Han J; Ogishi M; Gruber C; Markle J; Al Ali F; Rahman M; Khan T; Seeleuthner Y; Kerner G; Husquin LT; Maclsaac JL; Jeljeli M; Errami A; Ailal F; Kobor MS; Oleaga-Quintas C; Roynard M; Bourgey M; El Baghdadi J; Boisson-Dupuis S; Puel A; Batteux F; Rozenberg F; Marr N; Pan-Hammarström Q; Bogunovic D; Quintana-Murci L; Carroll T; Ma CS; Abel L; Bousfiha A; Di Santo JP; Glimcher LH; Gros P; Tangye SG; Sallusto F; Bustamante J; Casanova JL, 2020, 'Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria', Cell, 183, pp. 1826 - 1847.e31, http://dx.doi.org/10.1016/j.cell.2020.10.046

Ghosh S; Bal SK; Edwards ESJ; Pillay B; Heredia RJ; Cipe FE; Rao G; Salzer E; Zoghi S; Abolhassani H; Momen T; Gostick E; Price DA; Zhang Y; Oler AJ; Gonzaga-Jauregui C; Erman B; Metin A; Ilhan I; Haskologlu S; Islamoglu C; Baskin K; Ceylaner S; Yilmaz E; Unal E; Karakukcu M; Berghuis D; Cole T; Gupta AK; Hauck F; Kogler H; Hoepelman AIM; Baris S; Karakoc-Aydiner E; Ozen A; Kager L; Holzinger D; Paulussen M; Krüger R; Meisel R; Oommen PT; Morris E; Neven B; Worth A; van Montfrans J; Fraaij PLA; Choo S; Dogu F; Graham Davies E; Burns S; Dückers G; Becker RP; von Bernuth H; Latour S; Faraci M; Gattorno M; Su HC; Pan-Hammarström Q; Hammarström L; Lenardo MJ; Ma CS; Niehues T; Aghamohammadi A; Rezaei N; Ikinciogullari A; Tangye SG; Lankester AC; Boztug K, 2020, 'Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency', Blood, 136, pp. 2638 - 2655, http://dx.doi.org/10.1182/BLOOD.2020006738

Lucas CL; Tangye SG, 2020, 'Editorial: Human Disorders of PI3K Biology', Frontiers in Immunology, 11, http://dx.doi.org/10.3389/fimmu.2020.617464

Tangye SG, 2020, 'It's that time of year—APRIL promotes humoral immunity in humans', Journal of Allergy and Clinical Immunology, 146, pp. 1013 - 1015, http://dx.doi.org/10.1016/j.jaci.2020.09.005

Bastard P; Rosen LB; Zhang Q; Michailidis E; Hoffmann HH; Zhang Y; Dorgham K; Philippot Q; Rosain J; Béziat V; Manry J; Shaw E; Haljasmägi L; Peterson P; Lorenzo L; Bizien L; Trouillet-Assant S; Dobbs K; de Jesus AA; Belot A; Kallaste A; Catherinot E; Tandjaoui-Lambiotte Y; Le Pen J; Kerner G; Bigio B; Seeleuthner Y; Yang R; Bolze A; Spaan AN; Delmonte OM; Abers MS; Aiuti A; Casari G; Lampasona V; Piemonti L; Ciceri F; Bilguvar K; Lifton RP; Vasse M; Smadja DM; Migaud M; Hadjadj J; Terrier B; Duffy D; Quintana-Murci L; van de Beek D; Roussel L; Vinh DC; Tangye SG; Haerynck F; Dalmau D; Martinez-Picado J; Brodin P; Nussenzweig MC; Boisson-Dupuis S; Rodríguez-Gallego C; Vogt G; Mogensen TH; Oler AJ; Gu J; Burbelo PD; Cohen JI; Biondi A; Bettini LR; DÁngio M; Bonfanti P; Rossignol P; Mayaux J; Rieux-Laucat F; Husebye ES; Fusco F; Ursini MV; Imberti L; Sottini A; Paghera S; Quiros-Roldan E; Rossi C; Castagnoli R; Montagna D; Licari A; Marseglia GL; Duval X; Ghosn J; Tsang JS; Goldbach-Mansky R; Kisand K; Lionakis MS; Puel A; Zhang SY; Holland SM; Gorochov G; Jouanguy E; Rice CM; Cobat A; Notarangelo LD; Abel L; Su HC; Casanova JL; Arias AA; Darley D; Matthews G, 2020, 'Autoantibodies against type I IFNs in patients with life-threatening COVID-19', Science, 370, pp. eabd4585, http://dx.doi.org/10.1126/science.abd4585

Zhang Q; Liu Z; Moncada-Velez M; Chen J; Ogishi M; Bigio B; Yang R; Arias AA; Zhou Q; Han JE; Ugurbil AC; Zhang P; Rapaport F; Li J; Spaan AN; Boisson B; Boisson-Dupuis S; Bustamante J; Puel A; Ciancanelli MJ; Zhang SY; Béziat V; Jouanguy E; Abel L; Cobat A; Casanova JL; Bastard P; Korol C; Rosain J; Philippot Q; Chbihi M; Lorenzo L; Bizien L; Neehus AL; Kerner G; Seeleuthner Y; Manry J; Le Voyer T; Zhang SY; Le Voyer T; Zhang SY; Le Pen J; Schneider WM; Razooky BS; Hoffmann HH; Michailidis E; Rice CM; Sabli IKD; Hodeib S; Sancho-Shimizu V; Bilguvar K; Ye J; Maniatis T; Bolze A; Arias AA; Arias AA; Zhang Y; Notarangelo LD; Su HC; Zhang Y; Onodi F; Korniotis S; Karpf L; Soumelis V; Bonnet-Madin L; Amara A; Dorgham K; Gorochov G; Smith N; Duffy D; Moens L; Meyts I; Meade P; Darley D; Tangye S; Matthews G, 2020, 'Inborn errors of type I IFN immunity in patients with life-threatening COVID-19', Science, 370, pp. eabd4570, http://dx.doi.org/10.1126/science.abd4570

Bedford JG; Heinlein M; Garnham AL; Nguyen THO; Loudovaris T; Ge C; Mannering SI; Elliott M; Tangye SG; Kedzierska K; Gray DHD; Heath WR; Wakim LM, 2020, 'Unresponsiveness to inhaled antigen is governed by conventional dendritic cells and overridden during infection by monocytes', Science Immunology, 5, http://dx.doi.org/10.1126/sciimmunol.abb5439

Kong XF; Worley L; Rinchai D; Bondet V; Jithesh PV; Goulet M; Nonnotte E; Rebillat AS; Conte M; Mircher C; Gürtler N; Liu L; Migaud M; Elanbari M; Habib T; Ma CS; Bustamante J; Abel L; Ravel A; Lyonnet S; Munnich A; Duffy D; Chaussabel D; Casanova JL; Tangye SG; Boisson-Dupuis S; Puel A, 2020, 'Three Copies of Four Interferon Receptor Genes Underlie a Mild Type I Interferonopathy in Down Syndrome', Journal of Clinical Immunology, 40, pp. 807 - 819, http://dx.doi.org/10.1007/s10875-020-00803-9

Béziat V; Tavernier SJ; Chen YH; Ma CS; Materna M; Laurence A; Staal J; Aschenbrenner D; Roels L; Worley L; Claes K; Gartner L; Kohn LA; de Bruyne M; Schmitz-Abe K; Charbonnier LM; Keles S; Nammour J; Vladikine N; Renkilaraj MRLM; Seeleuthner Y; Migaud M; Rosain J; Jeljeli M; Boisson B; van Braeckel E; Rosenfeld JA; Dai H; Burrage LC; Murdock DR; Lambrecht BN; Avettand-Fenoel V; Vogel TP; Network UD; Esther CR; Haskologlu S; Dogu F; Ciznar P; Boutboul D; Ouachée-Chardin M; Amourette J; Lebras MN; Gauvain C; Tcherakian C; Ikinciogullari A; Beyaert R; Abel L; Milner JD; Grimbacher B; Couderc LJ; Butte MJ; Freeman AF; Catherinot É; Fieschi C; Chatila TA; Tangye SG; Uhlig HH; Haerynck F; Casanova JL; Puel A, 2020, 'Erratum: Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome (J. Exp. Med. (2020) 217:6 Doi:10.1084/jem.20191804)', Journal of Experimental Medicine, 217, http://dx.doi.org/10.1084/jem.2019180405272020c

Yap JY; Gloss B; Batten M; Hsu P; Berglund L; Cai F; Dai P; Parker A; Qiu M; Miley W; Roshan R; Marshall V; Whitby D; Wegman E; Garsia R; Wu KHC; Kirk E; Polizzotto M; Deenick EK; Tangye SG; Ma CS; CIRCA ; Phan TG, 2020, 'Everolimus-Induced Remission of Classic Kaposi’s Sarcoma Secondary to Cryptic Splicing Mediated CTLA4 Haploinsufficiency', Journal of Clinical Immunology, 40, pp. 774 - 779, http://dx.doi.org/10.1007/s10875-020-00804-8

Phan TG; Gray PE; Wong M; Macintosh R; Burnett L; Tangye SG, 2020, 'The Clinical Immunogenomics Research Consortium Australasia (CIRCA): a Distributed Network Model for Genomic Healthcare Delivery', Journal of Clinical Immunology, 40, pp. 763 - 766, http://dx.doi.org/10.1007/s10875-020-00787-6

Casanova JL; Su HC; Abel L; Aiuti A; Almuhsen S; Arias AA; Bastard P; Biggs C; Bogunovic D; Boisson B; Boisson-Dupuis S; Bolze A; Bondarenko A; Bousfiha A; Brodin P; Bustamante J; Butte M; Casari G; Ciancanelli M; Cobat A; Condino-Neto A; Cooper M; Dalgard C; Espinosa S; Feldman H; Fellay J; Franco JL; Hagin D; Itan Y; Jouanguy E; Lucas C; Mansouri D; Meyts I; Milner J; Mogensen T; Morio T; Ng L; Notarangelo LD; Okada S; Ozcelik T; Palacín PS; Planas A; Prando C; Puel A; Pujol A; Redin C; Renia L; Rodriguez Gallego JC; Quintana-Murci L; Sancho-Shimizu V; Sankaran V; Seppänen MRJ; Shahrooei M; Snow A; Spaan A; Tangye S; Tur JP; Turvey S; Vinh DC; von Bernuth H; Wang X; Zawadzki P; Zhang Q; Zhang S, 2020, 'A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection', Cell, 181, pp. 1194 - 1199, http://dx.doi.org/10.1016/j.cell.2020.05.016

Béziat V; Tavernier SJ; Chen YH; Ma CS; Materna M; Laurence A; Staal J; Aschenbrenner D; Roels L; Worley L; Claes K; Gartner L; Kohn LA; De Bruyne M; Schmitz-Abe K; Charbonnier LM; Keles S; Nammour J; Vladikine N; Renkilaraj MRLM; Seeleuthner Y; Migaud M; Rosain J; Jeljeli M; Boisson B; Van Braeckel E; Rosenfeld JA; Dai H; Burrage LC; Murdock DR; Lambrecht BN; Avettand-Fenoel V; Vogel TP; Esther CR; Haskologlu S; Dogu F; Ciznar P; Boutboul D; Ouachée-Chardin M; Amourette J; Lebras MN; Gauvain C; Tcherakian C; Ikinciogullari A; Beyaert R; Abel L; Milner JD; Grimbacher B; Couderc LJ; Butte MJ; Freeman AF; Catherinot É; Fieschi C; Chatila TA; Tangye SG; Uhlig HH; Haerynck F; Casanova JL; Puel A, 2020, 'Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome', Journal of Experimental Medicine, 217, http://dx.doi.org/10.1084/jem.20191804

Tangye SG, 2020, 'Genetic susceptibility to EBV infection: insights from inborn errors of immunity', Human Genetics, 139, pp. 885 - 901, http://dx.doi.org/10.1007/s00439-020-02145-3

Bucciol G; Pillay B; Casas-Martin J; Delafontaine S; Proesmans M; Lorent N; Coolen J; Tousseyn T; Bossuyt X; Ma CS; Schrijvers R; Tangye SG; Moens L; Meyts I, 2020, 'Systemic Inflammation and Myelofibrosis in a Patient with Takenouchi-Kosaki Syndrome due to CDC42 Tyr64Cys Mutation', Journal of Clinical Immunology, 40, pp. 567 - 570, http://dx.doi.org/10.1007/s10875-020-00742-5

Masle-Farquhar E; Payne K; Singh M; Rao G; Al-Eryani G; Jara C; Jackson K; Brink RA; Tangye S; Reed J; Goodnow CC, 2020, 'The effects of germline STAT3-activating mutations from autoimmunity and lymphoid malignancy on mouse and human T cells', The Journal of Immunology, 204, pp. 142.35 - 142.35, http://dx.doi.org/10.4049/jimmunol.204.supp.142.35

Fagbemi A; Newman WG; Tangye SG; Hughes SM; Arkwright PD; Cheesman E, 2020, 'Refractory very early-onset inflammatory bowel disease associated with cytosolic isoleucyl-tRNA synthetase deficiency: A case report', World Journal of Gastroenterology, 26, pp. 1841 - 1846, http://dx.doi.org/10.3748/WJG.V26.I15.1841

Tangye SG; Latour S, 2020, 'Primary immunodeficiencies reveal the molecular requirements for effective host defense against EBV infection', Blood, 135, pp. 644 - 655, http://dx.doi.org/10.1182/BLOOD.2019000928

Lau A; Avery DT; Jackson K; Lenthall H; Volpi S; Brigden H; Russell AJ; Bier J; Reed JH; Smart JM; Cole T; Choo S; Gray PE; Berglund LJ; Hsu P; Wong M; O'Sullivan M; Boztug K; Meyts I; Uzel G; Notarangelo LD; Brink R; Goodnow CC; Tangye SG; Deenick EK, 2020, 'Activated PI3Kd breaches multiple B cell tolerance checkpoints and causes autoantibody production', Journal of Experimental Medicine, 217, http://dx.doi.org/10.1084/jem_20191336

Klinken EM; Gray PE; Pillay B; Worley L; Edwards ESJ; Payne K; Bennetts B; Hung D; Wood BA; Chan JJ; Marshall GM; Mitchell R; Uzel G; Ma CS; Tangye SG; McLean-Tooke A, 2020, 'Diversity of XMEN Disease: Description of 2 Novel Variants and Analysis of the Lymphocyte Phenotype', Journal of Clinical Immunology, 40, pp. 299 - 309, http://dx.doi.org/10.1007/s10875-019-00732-2

Jouanguy E; Béziat V; Mogensen TH; Casanova JL; Tangye SG; Zhang SY, 2020, 'Human inborn errors of immunity to herpes viruses', Current Opinion in Immunology, 62, pp. 106 - 122, http://dx.doi.org/10.1016/j.coi.2020.01.004

Tangye SG; Al-Herz W; Bousfiha A; Chatila T; Cunningham-Rundles C; Etzioni A; Franco JL; Holland SM; Klein C; Morio T; Ochs HD; Oksenhendler E; Picard C; Puck J; Torgerson TR; Casanova JL; Sullivan KE, 2020, 'Correction to: Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee (Journal of Clinical Immunology, (2020), 40, 1, (24-64), 10.1007/s10875-019-00737-x)', Journal of Clinical Immunology, 40, pp. 65, http://dx.doi.org/10.1007/s10875-020-00763-0

Bousfiha A; Jeddane L; Picard C; Al-Herz W; Ailal F; Chatila T; Cunningham-Rundles C; Etzioni A; Franco JL; Holland SM; Klein C; Morio T; Ochs HD; Oksenhendler E; Puck J; Torgerson TR; Casanova JL; Sullivan KE; Tangye SG, 2020, 'Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification', Journal of Clinical Immunology, 40, pp. 66 - 81, http://dx.doi.org/10.1007/s10875-020-00758-x

Tangye SG; Al-Herz W; Bousfiha A; Chatila T; Cunningham-Rundles C; Etzioni A; Franco JL; Holland SM; Klein C; Morio T; Ochs HD; Oksenhendler E; Picard C; Puck J; Torgerson TR; Casanova JL; Sullivan KE, 2020, 'Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee', Journal of Clinical Immunology, 40, pp. 24 - 64, http://dx.doi.org/10.1007/s10875-019-00737-x

Tangye SG; Ma CS, 2020, 'Regulation of the germinal center and humoral immunity by interleukin-21', Journal of Experimental Medicine, 217, http://dx.doi.org/10.1084/jem.20191638

French MA; Tangye SG, 2020, 'The next generation of diagnostic tests for primary immunodeficiency disorders', Journal of Infectious Diseases, 221, pp. 1232 - 1234, http://dx.doi.org/10.1093/infdis/jiz230

Li J; Ritelli M; Ma CS; Rao G; Habib T; Corvilain E; Bougarn S; Cypowyj S; Grodecká L; Lévy R; Béziat V; Shang L; Payne K; Avery DT; Migaud M; Boucherit S; Boughorbel S; Guennoun A; Chrabieh M; Rapaport F; Bigio B; Itan Y; Boisson B; Cormier-Daire V; Syx D; Malfait F; Zoppi N; Abel L; Freiberger T; Dietz HC; Marr N; Tangye SG; Colombi M; Casanova JL; Puel A, 2019, 'Chronic mucocutaneous candidiasis and connective tissue disorder in humans with impaired JNK1-dependent responses to IL-17A/F and TGF-β', Science Immunology, 4, http://dx.doi.org/10.1126/sciimmunol.aax7965

Zammit NW; Siggs OM; Gray PE; Horikawa K; Langley DB; Walters SN; Daley SR; Loetsch C; Warren J; Yap JY; Cultrone D; Russell A; Malle EK; Villanueva JE; Cowley MJ; Gayevskiy V; Dinger ME; Brink R; Zahra D; Chaudhri G; Karupiah G; Whittle B; Roots C; Bertram E; Yamada M; Jeelall Y; Enders A; Clifton BE; Mabbitt PD; Jackson CJ; Watson SR; Jenne CN; Lanier LL; Wiltshire T; Spitzer MH; Nolan GP; Schmitz F; Aderem A; Porebski BT; Buckle AM; Abbott DW; Ziegler JB; Craig ME; Benitez-Aguirre P; Teo J; Tangye SG; King C; Wong M; Cox MP; Phung W; Tang J; Sandoval W; Wertz IE; Christ D; Goodnow CC; Grey ST, 2019, 'Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity', Nature Immunology, 20, pp. 1299 - 1310, http://dx.doi.org/10.1038/s41590-019-0492-0

Ma CS; Tangye SG, 2019, 'Flow Cytometric-Based Analysis of Defects in Lymphocyte Differentiation and Function Due to Inborn Errors of Immunity', Frontiers in Immunology, 10, http://dx.doi.org/10.3389/fimmu.2019.02108

Khourieh J; Rao G; Habib T; Avery DT; Lefèvre-Utile A; Chandesris MO; Belkadi A; Chrabieh M; Alwaseem H; Grandin V; Sarrot-Reynauld F; Sénéchal A; Lortholary O; Kong XF; Boisson-Dupuis S; Picard C; Puel A; Béziat V; Zhang Q; Abel L; Molina H; Marr N; Tangye SG; Casanova JL; Boissona B, 2019, 'A deep intronic splice mutation of STAT3 underlies hyper IgE syndrome by negative dominance', Proceedings of the National Academy of Sciences of the United States of America, 116, pp. 16463 - 16472, http://dx.doi.org/10.1073/pnas.1901409116

Bier J; Rao G; Payne K; Brigden H; French E; Pelham SJ; Lau A; Lenthall H; Edwards ESJ; Smart JM; Cole TS; Choo S; Joshi AY; Abraham RS; O'Sullivan M; Boztug K; Meyts I; Gray PE; Berglund LJ; Hsu P; Wong M; Holland SM; Notarangelo LD; Uzel G; Ma CS; Brink R; Tangye SG; Deenick EK, 2019, 'Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4⁺ T cells', Journal of Allergy and Clinical Immunology, 144, pp. 236 - 253, http://dx.doi.org/10.1016/j.jaci.2019.01.033

Frith K; Joly AL; Ma CS; Tangye SG; Lohse Z; Seitz C; Verge CF; Andersson J; Gray P, 2019, 'The FOXP3Δ2 isoform supports Treg cell development and protects against severe IPEX syndrome', Journal of Allergy and Clinical Immunology, 144, pp. 317 - 320.e8, http://dx.doi.org/10.1016/j.jaci.2019.03.003

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