By Professor William Ledger

Journal articles

Habibalahi A; Campbell JM; Bertoldo MJ; Mahbub SB; Goss DM; Ledger WL; Gilchrist RB; Wu LE; Goldys EM, 2022, 'Unique Deep Radiomic Signature Shows NMN Treatment Reverses Morphology of Oocytes from Aged Mice', Biomedicines, 10, http://dx.doi.org/10.3390/biomedicines10071544

Choi SKY; Venetis C; Ledger W; Havard A; Harris K; Norman RJ; Jorm LR; Chambers GM, 2022, 'Population-wide contribution of medically assisted reproductive technologies to overall births in Australia: Temporal trends and parental characteristics', Human Reproduction, 37, pp. 1047 - 1058, http://dx.doi.org/10.1093/humrep/deac032

Campbell JM; Mahbub SB; Bertoldo MJ; Habibalahi A; Goss DM; Ledger WL; Gilchrist RB; Wu LE; Goldys EM, 2022, 'Multispectral autofluorescence characteristics of reproductive aging in old and young mouse oocytes', Biogerontology, 23, pp. 237 - 249, http://dx.doi.org/10.1007/s10522-022-09957-y

Li HWR; Nelson SMG; Ledger WL, 2022, 'Editorial: Clinical Applications of Anti-Mullerian Hormone and Its Measurement in Reproductive Medicine and Women’s Health', Frontiers in Endocrinology, 13, http://dx.doi.org/10.3389/fendo.2022.879053

Crespi S; Hu XH; Johnson B; Griesinger G; Ledger WL; Heisel O; Kolibianakis EM, 2022, 'Patient burden and healthcare resource utilization of regimens for ovarian stimulation', Reproductive BioMedicine Online, 44, pp. 573 - 581, http://dx.doi.org/10.1016/j.rbmo.2021.03.019

Nesbitt-Hawes EM; Dietz HP; Ledger WL; Abbott JA, 2022, 'Four-dimensional ultrasound biometry following botulinum toxin type A injection to the pelvic floor', Neurourology and Urodynamics, 41, pp. 375 - 382, http://dx.doi.org/10.1002/nau.24833

XIONG T; PARIS VRODRIGUEZ; EDWARDS MC; COCHRAN BJ; RYE K-A; LEDGER WL; PADMANABHAN V; HANDELSMAN DJ; GILCHRIST RB; WALTERS KA, 2022, 'Androgen Actions in Adipose Tissue, But Not Skeletal Muscle, are Involved in the Development of Metabolic PCOS Features in a Mouse Model', Fertility & Reproduction, 04, pp. 169 - 169, http://dx.doi.org/10.1142/s2661318222740814

GILCHRIST RB; RICHANI D; CULLINAN R; DALATI S; TILIA L; ANAZODO A; LEDGER WL; RODGERS RJ, 2022, 'Application of Ex-Vivo In Vitro Maturation (IVM) to Fertility Preservation in Cancer Patients', Fertility & Reproduction, 04, pp. 133 - 133, http://dx.doi.org/10.1142/s2661318222740450

HABIBALAHI A; BERTOLDO MJ; MAHBUB SB; CAMPBELL JM; GOSS DM; LEDGER WL; GILCHRIST RB; WU LE; GOLDYS EM, 2022, 'Assessment of Oocyte Quality Using Deep Radiomic Signature of Oocyte Morphology in the Mouse', Fertility & Reproduction, 04, pp. 135 - 135, http://dx.doi.org/10.1142/s2661318222740474

SHYAMSUNDER A; HARDY T; YAZDANI A; POLYAKOV A; NORMAN R; HART R; AGRESTA F; ROMBAUTS L; BOOTHROYD C; CHAPMAN M; SWEETEN P; SOMERVILLE E; JOSE R; WAND H; LEDGER WL, 2022, 'Higher Doses of FSH Used for Superovulation Do Not Adversely Affect Embryonic Ploidy: A Randomised Controlled Trial (Stimulation Resulting in Embryonic Aneuploidy Using Menopur (STREAM) Trial)', Fertility & Reproduction, 04, pp. 142 - 142, http://dx.doi.org/10.1142/s2661318222740541

BIGGS S; LEWIS S; KENNEDY J; CHAMBERS G; MCLACHLAN R; O’BRYAN M; von SALDERN S; HART R; KHASHABA S; LEDGER W; NICOL C; ROMBAUTS L; STERN K; YAZDANI A; HALLIDAY J, 2022, 'Opportunities and Challenges Arising from the Australian Male Infertility Exposure (AMIE) Study', Fertility & Reproduction, 04, pp. 174 - 174, http://dx.doi.org/10.1142/s2661318222740851

HABIBALAHI A; CULLINAN R; TILLIA L; DALATI S; MAHBUB SB; CAMPBELL JM; RIEPSAMEN A; GILCHRIST RB; LEDGER WL; GOLDYS EM, 2022, 'Prediction of Progression from Oocyte to Useable Blastocyst Using Deep Radiomic Signatures: Preliminary Results', Fertility & Reproduction, 04, pp. 136 - 136, http://dx.doi.org/10.1142/s2661318222740486

RIEPSAMEN AH; DONOGHOE MW; INDRAN IR; LIEN S; HECHTMAN L; ROBERTSON DM; GILCHRIST RB; YONG E-L; LEDGER WL, 2022, 'Serum GDF9 and BMP15 as Markers of Ovarian Function in Healthy Women and Women with Polycystic Ovary Syndrome', Fertility & Reproduction, 04, pp. 141 - 141, http://dx.doi.org/10.1142/s266131822274053x

Ko JKY; Kan A; Leung P; Lee VCY; Li RHW; Ledger W; Ng EHY, 2021, 'Comparison of the number of oocytes obtained after ovarian stimulation between Chinese and Caucasian women undergoing in vitro fertilization using a standardized stimulation regime', Journal of Ovarian Research, 14, http://dx.doi.org/10.1186/s13048-021-00928-4

Rodgers RJ; Abbott JA; Walters KA; Ledger WL, 2021, 'Translational Physiology of Anti-Müllerian Hormone: Clinical Applications in Female Fertility Preservation and Cancer Treatment', Frontiers in Endocrinology, 12, pp. 689532, http://dx.doi.org/10.3389/fendo.2021.689532

Riepsamen AH; Donoghoe MW; Baerwald A; Pankhurst MW; Lien S; Chong YH; Robertson DM; Ledger WL; Gilchrist RB, 2021, 'Exploratory analysis of serum concentrations of oocyte biomarkers growth differentiation factor 9 and bone morphogenetic protein 15 in ovulatory women across the menstrual cycle', Fertility and Sterility, 116, pp. 546 - 557, http://dx.doi.org/10.1016/j.fertnstert.2021.02.001

Paris VR; Edwards MC; Aflatounian A; Bertoldo MJ; Ledger WL; Handelsman DJ; Gilchrist RB; Walters KA, 2021, 'Pathogenesis of reproductive and metabolic PCOSTraits in a mouse model', Journal of the Endocrine Society, 5, http://dx.doi.org/10.1210/jendso/bvab060

Li HWR; Robertson DM; Burns C; Ledger WL, 2021, 'Challenges in Measuring AMH in the Clinical Setting', Frontiers in Endocrinology, 12, http://dx.doi.org/10.3389/fendo.2021.691432

Riepsamen AH; Donoghoe MW; Baerwald A; Pankhurst MW; Lien S; Chong YH; Robertson DM; Ledger WL; Gilchrist RB, 2021, 'Serum Concentrations of GDF9 and BMP15 Across the Menstrual Cycle', Journal of the Endocrine Society, 5, pp. A734 - A735, http://dx.doi.org/10.1210/jendso/bvab048.1494

Chambers GM; Choi SKY; Irvine K; Venetis C; Harris K; Havard A; Norman RJ; Lui K; Ledger W; Jorm LR, 2021, 'A bespoke data linkage of an IVF clinical quality registry to population health datasets; methods and performance', International Journal of Population Data Science, 6, pp. 1679, http://dx.doi.org/10.23889/ijpds.v6i1.1679

Shyamsunder A; Hardy T; Yazdani A; Polyakov A; Norman R; Hart R; Agresta F; Rombauts L; Boothroyd C; Chapman M; Sweeten P; Somerville E; Jose R; Wand H; Ledger WL, 2021, 'Higher Doses of FSH Used for Superovulation Do Not Adversely Affect Embryonic Ploidy: A Randomized Controlled Trial (STimulation Resulting in Embryonic Aneuploidy using Menopur (STREAM) Trial)', Fertility & Reproduction, 03, pp. 108 - 114, http://dx.doi.org/10.1142/s2661318221500146

Rodriguez Paris V; Solon-Biet SM; Senior AM; Edwards MC; Desai R; Tedla N; Cox MJ; Ledger WL; Gilchrist RB; Simpson SJ; Handelsman DJ; Walters KA, 2020, 'Defining the impact of dietary macronutrient balance on PCOS traits', Nature Communications, 11, http://dx.doi.org/10.1038/s41467-020-19003-5

Ombelet W; van Eekelen R; McNally A; Ledger W; Doody K; Farquhar C, 2020, 'Should couples with unexplained infertility have three to six cycles of intrauterine insemination with ovarian stimulation or in vitro fertilization as first-line treatment?', Fertility and Sterility, 114, pp. 1141 - 1148, http://dx.doi.org/10.1016/j.fertnstert.2020.10.029

Chambers GM; Keller E; Choi S; Khalaf Y; Crawford S; Botha W; Ledger W, 2020, 'Funding and public reporting strategies for reducing multiple pregnancy from fertility treatments', Fertility and Sterility, 114, pp. 715 - 721, http://dx.doi.org/10.1016/j.fertnstert.2020.08.1405

Makeyeva Y; Nicol C; Ledger WL; Ryugo DK, 2020, 'Immunocytochemical Localization of Olfactory-signaling Molecules in Human and Rat Spermatozoa', Journal of Histochemistry and Cytochemistry, 68, pp. 491 - 513, http://dx.doi.org/10.1369/0022155420939833

Aflatounian A; Edwards MC; Paris VR; Bertoldo MJ; Desai R; Gilchrist RB; Ledger WL; Handelsman DJ; Walters KA, 2020, 'Androgen signaling pathways driving reproductive and metabolic phenotypes in a PCOS mouse model', Journal of Endocrinology, 245, pp. 381 - 395, http://dx.doi.org/10.1530/JOE-19-0530

Paris VR; Kaakoush NO; Solon-Biet SM; Edwards MC; Ledger WL; Gilchrist RB; Simpson SJ; Handelsman DJ; Walters KA, 2020, 'MON-022 Dissecting the Interplay Between Diet and PCOS Pathology on Gut Microbiota in a PCOS Mouse Model', Journal of the Endocrine Society, 4, http://dx.doi.org/10.1210/jendso/bvaa046.568

Cox MJ; Edwards MC; Aflatounian A; Paris VR; Ledger WL; Gilchrist RB; Handelsman DJ; Walters KA, 2020, 'SAT-018 Androgen Actions in Adipose Tissue and the Brain Are Key Mediators in the Development of Polycystic Ovary Syndrome', Journal of the Endocrine Society, 4, http://dx.doi.org/10.1210/jendso/bvaa046.088

Alshehre SM; Duffy S; Jones G; Ledger WL; Metwally M, 2020, 'A prospective, single-centre, single-arm, open label study of the long term use of a gonadotropin releasing hormone agonist (Triptorelin SR, 11.25 mg) in combination with Tibolone add-back therapy in the management of chronic cyclical pelvic pain', Reproductive Biology and Endocrinology, 18, http://dx.doi.org/10.1186/s12958-020-00586-z

Wang Y; Logan S; Stern K; Wakefield CE; Cohn RJ; Agresta F; Jayasinghe Y; Deans R; Segelov E; McLachlan RI; Gerstl B; Sullivan E; Ledger WE; Anazodo A, 2020, 'Supportive oncofertility care, psychological health and reproductive concerns: a qualitative study', Supportive Care in Cancer, 28, pp. 809 - 817, http://dx.doi.org/10.1007/s00520-019-04883-1

Raymer J; Guan Q; Norman RJ; Ledger W; Chambers GM, 2020, 'Projecting future utilization of medically assisted fertility treatments', Population Studies, 74, pp. 23 - 38, http://dx.doi.org/10.1080/00324728.2019.1676461

Cox MJ; Edwards MC; Paris VR; Aflatounian A; Ledger WL; Gilchrist RB; Padmanabhan V; Handelsman DJ; Walters KA, 2020, 'Androgen Action in Adipose Tissue and the Brain are Key Mediators in the Development of PCOS Traits in a Mouse Model', Endocrinology (United States), 161, pp. 1 - 15, http://dx.doi.org/10.1210/ENDOCR/BQAA061

Rozen G; Rogers P; Chander S; Anderson R; McNally O; Umstad M; Winship A; Hutt K; Teh WT; Dobrotwir A; Hart R; Ledger W; Stern K, 2020, 'Clinical summary guide: Reproduction in women with previous abdominopelvic radiotherapy or total body irradiation', Human Reproduction Open, 2020, http://dx.doi.org/10.1093/hropen/hoaa045

Ataman LM; Rodrigues JK; Marinho RM; Caetano JPJ; Chehin MB; Alves da Motta EL; Serafini P; Suzuki N; Furui T; Takae S; Sugishita Y; Morishige KI; Almeida-Santos T; Melo C; Buzaglo K; Irwin K; Hamish Wallace W; Anderson RA; Mitchell RT; Telfer EE; Adiga SK; Anazodo A; Stern C; Sullivan E; Jayasinghe Y; Orme L; Cohn R; McLachlan R; Deans R; Agresta F; Gerstl B; Ledger WL; Robker RL; de Meneses e Silva JM; Melo e Silva LHF; Lunardi FO; Lee JR; Suh CS; de Vos M; van Moer E; Stoop D; Vloeberghs V; Smitz J; Tournaye H; Wildt L; Winkler-Crepaz K; Andersen CY; Smith BM; Smith K; Woodruff TK, 2020, 'Creating a global community of practice for oncofertility', Journal of Global Oncology, 6, pp. 317 - 330, http://dx.doi.org/10.1200/JGO.2015.000307

Ataman LM; Rodrigues JK; Marinho RM; Caetano JPJ; Chehin MB; Alves da Motta EL; Serafini P; Suzuki N; Furui T; Takae S; Sugishita Y; Morishige K-I; Almeida-Santos T; Melo C; Buzaglo K; Irwin K; Wallace WH; Anderson RA; Mitchell RT; Telfer EE; Adiga SK; Anazodo A; Stern C; Sullivan E; Jayasinghe Y; Orme L; Cohn R; McLachlan R; Deans R; Agresta F; Gerstl B; Ledger WL; Robker RL; de Meneses E Silva JM; Melo E Silva LHF; Lunardi FO; Lee JR; Suh CS; De Vos M; Van Moer E; Stoop D; Vloeberghs V; Smitz J; Tournaye H; Wildt L; Winkler-Crepaz K; Andersen CY; Smith BM; Smith K; Woodruff TK, 2020, 'Creating a Global Community of Practice for Oncofertility.', JCO Glob Oncol, 6, pp. 317 - 330, http://dx.doi.org/10.1200/GO.22.00007

Ledger W, 2019, 'Preimplantation genetic screening should be used in all in vitro fertilisation cycles in women over the age of 35 years: AGAINST: Pre-implantation genetic screening should not be used in all IVF cycles in women over the age of 35 years', BJOG: An International Journal of Obstetrics and Gynaecology, 126, pp. 1555, http://dx.doi.org/10.1111/1471-0528.15942

Anazodo A; Laws P; Logan S; Saunders C; Travaglia J; Gerstl B; Bradford N; Cohn R; Birdsall M; Barr R; Suzuki N; Takae S; Marinho R; Xiao S; Chen QH; Mahajan N; Patil M; Gunasheela D; Smith K; Sender L; Melo C; Almeida-Santos T; Salama M; Appiah L; Su I; Lane S; Woodruff TK; Pacey A; Anderson RA; Shenfield F; Sullivan E; Ledger W, 2019, 'The Development of an International Oncofertility Competency Framework: A Model to Increase Oncofertility Implementation', Oncologist, 24, pp. e1450 - e1459, http://dx.doi.org/10.1634/theoncologist.2019-0043

Chambers GM; Harrison C; Raymer J; Raymer AKP; Britt H; Chapman M; Ledger W; Norman RJ, 2019, 'Infertility management in women and men attending primary care - Patient characteristics, management actions and referrals', Human Reproduction, 34, pp. 2173 - 2183, http://dx.doi.org/10.1093/humrep/dez172

Costello M; Garad R; Hart R; Homer H; Johnson L; Jordan C; Mocanu E; Qiao J; Rombauts L; Teede HJ; Vanky E; Venetis C; Ledger W, 2019, 'A Review of First Line Infertility Treatments and Supporting Evidence in Women with Polycystic Ovary Syndrome', Medical sciences (Basel, Switzerland), 7, http://dx.doi.org/10.3390/medsci7090095

Fraison E; Crawford G; Casper G; Harris V; Ledger W, 2019, 'Pregnancy following diagnosis of premature ovarian insufficiency: a systematic review', Reproductive BioMedicine Online, 39, pp. 467 - 476, http://dx.doi.org/10.1016/j.rbmo.2019.04.019

Riepsamen AH; Chan K; Lien S; Sweeten P; Donoghoe MW; Walker G; Fraison EHJ; Stocker WA; Walton KL; Harrison CA; Ledger WL; Robertson DM; Gilchrist RB, 2019, 'Serum Concentrations of Oocyte-Secreted Factors BMP15 and GDF9 during IVF and in Women with Reproductive Pathologies', Endocrinology, 160, pp. 2298 - 2313, http://dx.doi.org/10.1210/en.2019-00264

Costello MF; Garad RM; Hart R; Homer H; Johnson L; Jordan C; Mocanu E; Qiao J; Rombauts L; Teede HJ; Vanky E; Venetis CA; Ledger WL, 2019, 'A Review of Second- and Third-line Infertility Treatments and Supporting Evidence in Women with Polycystic Ovary Syndrome', Medical sciences (Basel, Switzerland), 7, http://dx.doi.org/10.3390/medsci7070075

Anazodo A; Ledger W, 2019, 'Assessing and Supporting Adolescent Boys Having Fertility Preservation', In: Woodruff T., Shah D., Vitek W. (eds) Textbook of Oncofertility Research and Practice., pp. 507 - 512, http://dx.doi.org/10.1007/978-3-030-02868-8_53

Rodriguez Paris V; Solon-Biet S; Edwards M; Cox M; Ledger W; Gilchrist R; Simpson S; Handelsman D; Walters K, 2019, 'MON-231 Dietary Interventions Can Ameliorate Polycystic Ovary Syndrome (PCOS) Traits in a PCOS Mouse Model', Journal of the Endocrine Society, 3, http://dx.doi.org/10.1210/js.2019-mon-231

Aflatounian A; Edwards M; Gilchrist R; Bertoldo M; Ledger W; Handelsman D; Walters K, 2019, 'OR08-2 Androgen Receptor- Vs Estrogen Receptor-Mediated Actions in the Development of Distinct Clinical Polycystic Ovary Syndrome (PCOS) Phenotypes', Journal of the Endocrine Society, 3, http://dx.doi.org/10.1210/js.2019-or08-2

Bertoldo MJ; Caldwell ASL; Riepsamen AH; Lin D; Gonzalez MB; Robker RL; Ledger WL; Gilchrist RB; Handelsman DJ; Walters KA, 2019, 'A hyperandrogenic environment causes intrinsic defects that are detrimental to follicular dynamics in a PCOS mouse model', Endocrinology, 160, pp. 699 - 715, http://dx.doi.org/10.1210/en.2018-00966

Richani D; Constance K; Lien S; Agapiou D; Stocker WA; Hedger MP; Ledger WL; Thompson JG; Robertson DM; Mottershead DG; Walton KL; Harrison CA; Gilchrist RB, 2019, 'Cumulin and FSH cooperate to regulate inhibin B and activin B production by human granulosa-lutein cells in vitro', Endocrinology, 160, pp. 853 - 862, http://dx.doi.org/10.1210/en.2018-01026

Weddell S; Jones GL; Duffy S; Hogg C; Johnson S; Ledger W, 2019, 'Home ovulation test use and stress during subfertility evaluation: Subarm of a randomized controlled trial', Women's Health, 15, http://dx.doi.org/10.1177/1745506519838363

Crawford GE; Ledger WL, 2019, 'In vitro fertilisation/intracytoplasmic sperm injection beyond 2020', BJOG: An International Journal of Obstetrics and Gynaecology, 126, pp. 237 - 243, http://dx.doi.org/10.1111/1471-0528.15526

Hardy T; Ledger W; Scott H, 2019, '28. KARYOMAPPING USING WHOLE GENOME SEQUENCING DATA: PRECLINICAL VALIDATION OF A PERSONALISED APPROACH TO PGT-M', Reproductive BioMedicine Online, 39, pp. e43 - e44, http://dx.doi.org/10.1016/j.rbmo.2019.04.081

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