Select Publications

Journal articles

Cox MJ; Edwards MC; Rodriguez Paris V; Aflatounian A; Ledger WL; Gilchrist RB; Padmanabhan V; Handelsman DJ; Walters KA, 2020, 'Androgen action in adipose tissue and the brain are key mediators in the development of PCOS traits in a mouse model.', Endocrinology, http://dx.doi.org/10.1210/endocr/bqaa061

Alshehre SM; Duffy S; Jones G; Ledger WL; Metwally M, 2020, 'A prospective, single-centre, single-arm, open label study of the long term use of a gonadotropin releasing hormone agonist (Triptorelin SR, 11.25 mg) in combination with Tibolone add-back therapy in the management of chronic cyclical pelvic pain', Reproductive Biology and Endocrinology, vol. 18, pp. 28, http://dx.doi.org/10.1186/s12958-020-00586-z

Wang Y; Logan S; Stern K; Wakefield CE; Cohn RJ; Agresta F; Jayasinghe Y; Deans R; Segelov E; McLachlan RI; Gerstl B; Sullivan E; Ledger WE; Anazodo A, 2020, 'Supportive oncofertility care, psychological health and reproductive concerns: a qualitative study', Supportive Care in Cancer, vol. 28, pp. 809 - 817, http://dx.doi.org/10.1007/s00520-019-04883-1

Raymer J; Guan Q; Norman RJ; Ledger W; Chambers GM, 2020, 'Projecting future utilization of medically assisted fertility treatments', Population Studies, vol. 74, pp. 23 - 38, http://dx.doi.org/10.1080/00324728.2019.1676461

Ataman LM; Rodrigues JK; Marinho RM; Caetano JPJ; Chehin MB; Alves da Motta EL; Serafini P; Suzuki N; Furui T; Takae S; Sugishita Y; Morishige KI; Almeida-Santos T; Melo C; Buzaglo K; Irwin K; Hamish Wallace W; Anderson RA; Mitchell RT; Telfer EE; Adiga SK; Anazodo A; Stern C; Sullivan E; Jayasinghe Y; Orme L; Cohn R; McLachlan R; Deans R; Agresta F; Gerstl B; Ledger WL; Robker RL; de Meneses e Silva JM; Melo e Silva LHF; Lunardi FO; Lee JR; Suh CS; de Vos M; van Moer E; Stoop D; Vloeberghs V; Smitz J; Tournaye H; Wildt L; Winkler-Crepaz K; Andersen CY; Smith BM; Smith K; Woodruff TK, 2020, 'Creating a global community of practice for oncofertility', Journal of Global Oncology, vol. 6, pp. 317 - 330, http://dx.doi.org/10.1200/JGO.2015.000307

Aflatounian A; Edwards MC; Rodriguez Paris V; Bertoldo MJ; Desai R; Gilchrist RB; Ledger WL; Handelsman DJ; Walters KA, 2020, 'Androgen signaling pathways driving reproductive and metabolic phenotypes in a PCOS mouse model.', J Endocrinol, vol. 245, pp. 381 - 395, http://dx.doi.org/10.1530/JOE-19-0530

Anazodo A; Laws P; Logan S; Saunders C; Travaglia J; Gerstl B; Bradford N; Cohn R; Birdsall M; Barr R; Suzuki N; Takae S; Marinho R; Xiao S; Chen QH; Mahajan N; Patil M; Gunasheela D; Smith K; Sender L; Melo C; Almeida-Santos T; Salama M; Appiah L; Su I; Lane S; Woodruff TK; Pacey A; Anderson RA; Shenfield F; Sullivan E; Ledger W, 2019, 'The Development of an International Oncofertility Competency Framework: A Model to Increase Oncofertility Implementation', Oncologist, vol. 24, pp. e1450 - e1459, http://dx.doi.org/10.1634/theoncologist.2019-0043

Chambers GM; Harrison C; Raymer J; Raymer AKP; Britt H; Chapman M; Ledger W; Norman RJ, 2019, 'Infertility management in women and men attending primary care - Patient characteristics, management actions and referrals', Human Reproduction, vol. 34, pp. 2173 - 2183, http://dx.doi.org/10.1093/humrep/dez172

Costello M; Garad R; Hart R; Homer H; Johnson L; Jordan C; Mocanu E; Qiao J; Rombauts L; Teede HJ; Vanky E; Venetis C; Ledger W, 2019, 'A Review of First Line Infertility Treatments and Supporting Evidence in Women with Polycystic Ovary Syndrome.', Med Sci (Basel), vol. 7, pp. 95 - 95, http://dx.doi.org/10.3390/medsci7090095

Fraison E; Crawford G; Casper G; Harris V; Ledger W, 2019, 'Pregnancy following diagnosis of premature ovarian insufficiency: a systematic review', Reproductive BioMedicine Online, vol. 39, pp. 467 - 476, http://dx.doi.org/10.1016/j.rbmo.2019.04.019

Riepsamen AH; Chan K; Lien S; Sweeten P; Donoghoe MW; Walker G; Fraison EHJ; Stocker WA; Walton KL; Harrison CA; Ledger WL; Robertson DM; Gilchrist RB, 2019, 'Serum Concentrations of Oocyte-Secreted Factors BMP15 and GDF9 during IVF and in Women with Reproductive Pathologies', Endocrinology, vol. 160, pp. 2298 - 2313, http://dx.doi.org/10.1210/en.2019-00264

Costello MF; Garad RM; Hart R; Homer H; Johnson L; Jordan C; Mocanu E; Qiao J; Rombauts L; Teede HJ; Vanky E; Venetis CA; Ledger WL, 2019, 'A Review of Second- and Third-line Infertility Treatments and Supporting Evidence in Women with Polycystic Ovary Syndrome.', Med Sci (Basel), vol. 7, http://dx.doi.org/10.3390/medsci7070075

Bertoldo MJ; Caldwell ASL; Riepsamen AH; Lin D; Gonzalez MB; Robker RL; Ledger WL; Gilchrist RB; Handelsman DJ; Walters KA, 2019, 'A hyperandrogenic environment causes intrinsic defects that are detrimental to follicular dynamics in a PCOS mouse model', Endocrinology, vol. 160, pp. 699 - 715, http://dx.doi.org/10.1210/en.2018-00966

Richani D; Constance K; Lien S; Agapiou D; Stocker WA; Hedger MP; Ledger WL; Thompson JG; Robertson DM; Mottershead DG; Walton KL; Harrison CA; Gilchrist RB, 2019, 'Cumulin and FSH cooperate to regulate inhibin B and activin B production by human granulosa-lutein cells in vitro', Endocrinology, vol. 160, pp. 853 - 862, http://dx.doi.org/10.1210/en.2018-01026

Weddell S; Jones GL; Duffy S; Hogg C; Johnson S; Ledger W, 2019, 'Home ovulation test use and stress during subfertility evaluation: Subarm of a randomized controlled trial', Women's Health, vol. 15, pp. 1745506519838363, http://dx.doi.org/10.1177/1745506519838363

Crawford GE; Ledger WL, 2019, 'In vitro fertilisation/intracytoplasmic sperm injection beyond 2020', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 126, pp. 237 - 243, http://dx.doi.org/10.1111/1471-0528.15526

Anazodo A; Ledger W, 2019, 'Assessing and Supporting Adolescent Boys Having Fertility Preservation', In: Woodruff T., Shah D., Vitek W. (eds) Textbook of Oncofertility Research and Practice., pp. 507 - 512, http://dx.doi.org/10.1007/978-3-030-02868-8_53

Ledger W, 2019, 'Preimplantation genetic screening should be used in all in vitro fertilisation cycles in women over the age of 35 years: AGAINST: Pre-implantation genetic screening should not be used in all IVF cycles in women over the age of 35 years', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 126, pp. 1555, http://dx.doi.org/10.1111/1471-0528.15942

Walters KA; Gilchrist RB; Ledger WL; Teede HJ; Handelsman DJ; Campbell RE, 2018, 'New Perspectives on the Pathogenesis of PCOS: Neuroendocrine Origins', Trends in Endocrinology and Metabolism, vol. 29, pp. 841 - 852, http://dx.doi.org/10.1016/j.tem.2018.08.005

Vogt KS; Hughes J; Wilkinson A; Mahmoodi N; Skull J; Wood H; McDougall S; Slade P; Greenfield DM; Pacey A; Ledger W; Jones GL, 2018, 'Preserving fertility in women with cancer (PreFer): Decision-making and patient-reported outcomes in women offered egg and embryo freezing prior to cancer treatment', Psycho-Oncology, vol. 27, pp. 2725 - 2732, http://dx.doi.org/10.1002/pon.4866

Anazodo A; Paula L; Logan S; Saunders C; Travaglia J; Gerstl B; Bradford N; Cohn R; Birdsall M; Barr R; Suzuki N; Seido T; Marinho R; Xiao S; Qiang-Hua C; Mahajan N; Patil M; Gunasheela D; Smith K; Sender L; Melo C; Almeida-Santos T; Salama M; Appiah L; Su I; Lane S; Woodruff T; Pacey A; Anderson RA; Shenfield F; Ledger W; Sullivan E, 2018, 'How can we improve oncofertility care for patients? A systematic scoping review of current international practice and models of care.', Human Reproduction Update, http://dx.doi.org/10.1093/humupd/dmy038

Deans R; Vancaillie T; Ledger W; Liu J; Abbott JA, 2018, 'Live birth rate and obstetric complications following the hysteroscopic management of intrauterine adhesions including Asherman syndrome', Human Reproduction, vol. 33, pp. 1847 - 1853, http://dx.doi.org/10.1093/humrep/dey237

Bertoldo MJ; Walters KA; Ledger WL; Gilchrist RB; Mermillod P; Locatelli Y, 2018, 'In-vitro regulation of primordial follicle activation: challenges for fertility preservation strategies', Reproductive BioMedicine Online, vol. 36, pp. 491 - 499, http://dx.doi.org/10.1016/j.rbmo.2018.01.014

Storr A; Venetis C; Cooke S; Kilani S; Ledger W, 2018, 'Time-lapse algorithms and morphological selection of day-5 embryos for transfer: a preclinical validation study', Fertility and Sterility, vol. 109, pp. 276 - 283.e3, http://dx.doi.org/10.1016/j.fertnstert.2017.10.036

Ledger W, 2018, 'Preface – Vol. 53', Best Practice and Research: Clinical Obstetrics and Gynaecology, vol. 53, pp. 1 - 2, http://dx.doi.org/10.1016/j.bpobgyn.2018.10.005

Jones G; Hughes J; Mahmoodi N; Smith E; Skull J; Ledger W, 2017, 'What factors hinder the decision-making process for women with cancer and contemplating fertility preservation treatment?', Human Reproduction Update, vol. 23, pp. 433 - 457, http://dx.doi.org/10.1093/humupd/dmx009

McCredie S; Ledger W; Venetis CA, 2017, 'Anti-Müllerian hormone kinetics in pregnancy and post-partum: a systematic review', Reproductive BioMedicine Online, vol. 34, pp. 522 - 533, http://dx.doi.org/10.1016/j.rbmo.2017.02.005

Rodgers RJ; Reid GD; Koch J; Deans R; Ledger WL; Friedlander M; Gilchrist RB; Walters KA; Abbott JA, 2017, 'The safety and efficacy of controlled ovarian hyperstimulation for fertility preservation in women with early breast cancer: A systematic review', Human Reproduction, vol. 32, pp. 1033 - 1045, http://dx.doi.org/10.1093/humrep/dex027

Patanwala IY; Lamvu G; Ledger WJ; Witzeman K; Marvel R; Rapkin A; Bongiovanni AM; Feranec J; Witkin SS, 2017, 'Catechol-O-methyltransferase gene polymorphism and vulvar pain in women with vulvodynia', American Journal of Obstetrics and Gynecology, vol. 216, pp. 395.e1 - 395.e6, http://dx.doi.org/10.1016/j.ajog.2016.10.020

Nasioudis D; Linhares IM; Ledger WJ; Witkin SS, 2017, 'Bacterial vaginosis: a critical analysis of current knowledge', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 124, pp. 61 - 69, http://dx.doi.org/10.1111/1471-0528.14209

Storr A; Venetis CA; Cooke S; Kilani S; Ledger W, 2017, 'Inter-observer and intra-observer agreement between embryologists during selection of a single Day 5 embryo for transfer: A multicenter study', Human Reproduction, vol. 32, pp. 307 - 314, http://dx.doi.org/10.1093/humrep/dew330

Ledger WL, 2017, 'The HFEA should be regulating add-on treatments for IVF/ICSI', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 124, pp. 1850, http://dx.doi.org/10.1111/1471-0528.14670

Ledger WL, 2017, 'A history of mental illness, but not of conception with assisted reproductive technology, puts patients at increased risk of severe postnatal depression', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 124, pp. 443, http://dx.doi.org/10.1111/1471-0528.13792

Chambers GM; Wand H; Macaldowie A; Chapman MG; Farquhar CM; Bowman M; Molloy D; Ledger W, 2016, 'Population trends and live birth rates associated with common ART treatment strategies', Human Reproduction, vol. 31, pp. 2632 - 2641, http://dx.doi.org/10.1093/humrep/dew232

Anazodo AC; Stern CJ; Mclachlan RI; Gerstl B; Agresta F; Cohn RJ; Jayasinghe Y; Wakefield CE; Daly G; Chan D; Gilbert L; Kemertzis M; Orme LM; Wand H; Viney R; Gillam L; Deans R; Jetti M; Wu J; Chapman M; Ledger W; Sullivan EA, 2016, 'A study protocol for the australasian oncofertility registry: Monitoring referral patterns and the uptake, quality, and complications of fertility preservation strategies in Australia and New Zealand', Journal of Adolescent and Young Adult Oncology, vol. 5, pp. 215 - 225, http://dx.doi.org/10.1089/jayao.2015.0062

Anazodo AC; Gerstl B; Stern CJ; Mclachlan RI; Agresta F; Jayasinghe Y; Cohn RJ; Wakefield CE; Chapman M; Ledger W; Sullivan EA, 2016, 'Utilizing the experience of consumers in consultation to develop the australasian oncofertility consortium charter', Journal of Adolescent and Young Adult Oncology, vol. 5, pp. 232 - 239, http://dx.doi.org/10.1089/jayao.2015.0056

Wang X; Gook DA; Walters KA; Anazodo A; Ledger WL; Gilchrist RB, 2016, 'Improving fertility preservation for girls and women by coupling oocyte in vitro maturation with existing strategies', Women's Health, vol. 12, pp. 275 - 278, http://dx.doi.org/10.2217/whe-2016-0019

Robertson DM; Gilchrist RB; Ledger WL; Baerwald A, 2016, 'Random start or emergency IVF/in vitro maturation: A new rapid approach to fertility preservation', Women's Health, vol. 12, pp. 339 - 349, http://dx.doi.org/10.2217/whe-2015-0001

Lim HJ; Ledger W, 2016, 'Targeted therapy in ovarian cancer', Women's Health, vol. 12, pp. 363 - 378, http://dx.doi.org/10.2217/whe.16.4

Jones GL; Jacques RM; Thompson J; Wood HJ; Hughes J; Ledger W; Alazzam M; Radley SC; Tidy JA, 2016, 'The impact of surgery for vulval cancer upon health-related quality of life and pelvic floor outcomes during the first year of treatment: a longitudinal, mixed methods study', Psycho-Oncology, pp. 656 - 662, http://dx.doi.org/10.1002/pon.3992

Ledger WL; Turner MJ, 2016, 'Implementation of the findings of a national enquiry into the misdiagnosis of miscarriage in the Republic of Ireland: impact on quality of clinical care', Fertility and sterility, vol. 105, pp. 417 - 422, http://dx.doi.org/10.1016/j.fertnstert.2015.11.002

Ledger W, 2016, 'A history of mental illness, but not of conception with assisted reproductive technology, puts patients at increased risk of severe postnatal depression', BJOG: An International Journal of Obstetrics and Gynaecology, http://dx.doi.org/10.1111/1471-0528.13792

Ledger WL, 2016, 'Superfertility is more prevalent in obese women with recurrent early pregnancy miscarriage', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 123, pp. 223, http://dx.doi.org/10.1111/1471-0528.13815

Ledger W; Johnson MH, 2016, 'One plus one equals two: Why fetal reduction is always a second-best solution', Reproductive BioMedicine Online, vol. 32, pp. 467 - 468, http://dx.doi.org/10.1016/j.rbmo.2016.03.002

McCullough K; Ledger W, 2016, 'Anti-Müllerian hormone is all you need: An assisted reproductive technology perspective in diagnosing polycystic ovary syndrome', Women's Health, vol. 12, pp. 263 - 265, http://dx.doi.org/10.2217/whe-2016-0005

Ledger WL; Turner MJ, 2016, 'Implementation of the findings of a national enquiry into the misdiagnosis of miscarriage in the Republic of Ireland: impact on quality of clinical care', Fertility and Sterility, vol. 105, pp. 417 - 422, http://dx.doi.org/10.1016/j.fertnstert.2015.11.002

Jones G; Carlton J; Weddell S; Johnson S; Ledger WL, 2015, 'Women's experiences of ovulation testing: A qualitative analysis', Reproductive Health, vol. 12, http://dx.doi.org/10.1186/s12978-015-0103-y

Storr A; Venetis CA; Cooke S; Susetio D; Kilani S; Ledger W, 2015, 'Morphokinetic parameters using time-lapse technology and day 5 embryo quality: a prospective cohort study', Journal of Assisted Reproduction and Genetics, vol. 32, pp. 1151 - 1160, http://dx.doi.org/10.1007/s10815-015-0534-y

Coughlan C; Clarke H; Cutting R; Saxton J; Waite S; Ledger W; Li T; Pacey AA, 2015, 'Sperm DNA fragmentation, recurrent implantation failure and recurrent miscarriage', Asian Journal of Andrology, vol. 17, pp. 681 - 685, http://dx.doi.org/10.4103/1008-682X.144946

Riepsamen A; Wu L; Lau L; Listijono D; Ledger W; Sinclair DA; Homer H, 2015, 'Erratum: Nicotinamide impairs entry into and exit from meiosis I in mouse oocytes (PLoS ONE (2015) 10:5 (e0126194) DOI:10.1371/journal.pone.0126194)', PLoS ONE, vol. 10, http://dx.doi.org/10.1371/journal.pone.0126194


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