By Associate Professor Venessa Therese Chin

Journal articles

Johns AL; McKay SH; Humphris JL; Pinese M; Chantrill LA; Mead RS; Tucker K; Andrews L; Goodwin A; Leonard C; High HA; Nones K; Waddell N; Patch AM; Merrett ND; Pavlakis N; Kassahn KS; Samra JS; Miller DK; Chang DK; Pajic M; Pearson JV; Grimmond SM; Zeps N; Gill AJ; Biankin AV; Chin VT; Chou A; Steinmann A; Arshi M; Drury A; Froio D; Morgan A; Timpson P; Hermann D; Vennin C; Warren S; Wu J; Pinho AV; Newell F; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Wood S; Xu C; Hofmann O; Wilson PJ; Christ A; Bruxner T; Samra S; Arena J; Mittal A; Asghari R; Pavey D; Das A; Cosman PH; Ismail K; O'Connnor C; Williams D; Spigellman A; Lam W; McLeod D; Nagrial AM; Kirk J; James V; Grimison P; Cooper CL; Sandroussi C; Forest C; Epari KP; Ballal M; Fletcher DR; Mukhedkar S; Beilin M; Feeney K; Nguyen NQ; Ruszkiewicz AR; Worthley C; Brooke-Smith ME; Papangelis V; Clouston AD; Martin P; Barbour AP; O'Rourke TJ; Fawcett JW; Slater K; Hatzifotis M; Hodgkinson P; Hruban RH; Wolfgang CL; Hodgin M; Lawlor RT; Beghelli S; Corbo V; Scardoni M; Bassi C; Bailey P; Martin S; Musgrove EA; Herrmann D, 2017, 'Lost in translation: Returning germline genetic results in genome-scale cancer research', Genome Medicine, 9, pp. 41, http://dx.doi.org/10.1186/s13073-017-0430-4

Vennin C; Chin VT; Warren SC; Lucas MC; Herrmann D; Magenau A; Melenec P; Walters SN; Del Monte-Nieto G; Conway JRW; Nobis M; Allam AH; McCloy RA; Currey N; Pinese M; Boulghourjian A; Zaratzian A; Adam AAS; Heu C; Nagrial AM; Chou A; Steinmann A; Drury A; Froio D; Giry-Laterriere M; Harris NLE; Phan T; Jain R; Weninger W; McGhee EJ; Whan R; Johns AL; Samra JS; Chantrill L; Gill AJ; Kohonen-Corish M; Harvey RP; Biankin AV; Evans TRJ; Anderson KI; Grey ST; Ormandy CJ; Gallego-Ortega D; Wang Y; Samuel MS; Sansom OJ; Burgess A; Cox TR; Morton JP; Pajic M; Timpson P, 2017, 'Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis', Science Translational Medicine, 9, http://dx.doi.org/10.1126/scitranslmed.aai8504

Scarpa A; Chang DK; Nones K; Corbo V; Patch AM; Bailey P; Lawlor RT; Johns AL; Miller DK; Mafficini A; Rusev B; Scardoni M; Antonello D; Barbi S; Sikora KO; Cingarlini S; Vicentini C; McKay S; Quinn MCJ; Bruxner TJC; Christ AN; Harliwong I; Idrisoglu S; McLean S; Nourse C; Nourbakhsh E; Wilson PJ; Anderson MJ; Fink JL; Newell F; Waddell N; Holmes O; Kazakoff SH; Leonard C; Wood S; Xu Q; Nagaraj SH; Amato E; Dalai I; Bersani S; Cataldo I; Dei Tos AP; Capelli P; Davì MV; Landoni L; Malpaga A; Miotto M; Whitehall VLJ; Leggett BA; Harris JL; Harris J; Jones MD; Humphris J; Chantrill LA; Chin V; Nagrial AM; Pajic M; Scarlett CJ; Pinho A; Rooman I; Toon C; Wu J; Pinese M; Cowley M; Barbour A; Mawson A; Humphrey ES; Colvin EK; Chou A; Lovell JA; Jamieson NB; Duthie F; Gingras MC; Fisher WE; Dagg RA; Lau LMS; Lee M; Pickett HA; Reddel RR; Samra JS; Kench JG; Merrett ND; Epari K; Nguyen NQ; Zeps N; Falconi M; Simbolo M; Butturini G; Van Buren G; Partelli S; Fassan M; Khanna KK; Gill AJ; Wheeler DA; Gibbs RA; Musgrove EA; Bassi C; Tortora G; Pederzoli P; Pearson JV, 2017, 'Whole-genome landscape of pancreatic neuroendocrine tumours', Nature, 543, pp. 65 - 71, http://dx.doi.org/10.1038/nature21063

Humphris JL; Patch AM; Nones K; Bailey PJ; Johns AL; McKay S; Chang DK; Miller DK; Pajic M; Kassahn KS; Quinn MCJ; Bruxner TJC; Christ AN; Harliwong I; Idrisoglu S; Manning S; Nourse C; Nourbakhsh E; Stone A; Wilson PJ; Anderson M; Fink JL; Holmes O; Kazakoff S; Leonard C; Newell F; Waddell N; Wood S; Mead RS; Xu Q; Wu J; Pinese M; Cowley MJ; Jones MD; Nagrial AM; Chin VT; Chantrill LA; Mawson A; Chou A, 2017, 'Hypermutation In Pancreatic Cancer', Gastroenterology, 152, pp. 68 - 74.e2, http://dx.doi.org/10.1053/j.gastro.2016.09.060

Bailey P; Chang DK; Nones K; Johns AL; Patch AM; Gingras MC; Miller DK; Christ AN; Bruxner TJC; Quinn MC; Nourse C; Murtaugh LC; Harliwong I; Idrisoglu S; Manning S; Nourbakhsh E; Wani S; Fink L; Holmes O; Chin V; Anderson MJ; Kazakoff S; Leonard C; Newell F; Waddell N; Wood S; Xu Q; Wilson PJ; Cloonan N; Kassahn KS; Taylor D; Quek K; Robertson A; Pantano L; Mincarelli L; Sanchez LN; Evers L; Wu J; Pinese M; Cowley MJ; Jones MD; Colvin EK; Nagrial AM; Humphrey ES; Chantrill LA; Mawson A; Humphris J; Chou A; Pajic M; Scarlett CJ; Pinho AV; Giry-Laterriere M; Rooman I; Samra JS; Kench JG; Lovell JA; Merrett ND; Toon CW; Epari K; Nguyen NQ; Barbour A; Zeps N; Moran-Jones K; Jamieson NB; Graham JS; Duthie F; Oien K; Hair J; Grützmann R; Maitra A; Iacobuzio-Donahue CA; Wolfgang CL; Morgan RA; Lawlor RT; Corbo V; Bassi C; Rusev B; Capelli P; Salvia R; Tortora G; Mukhopadhyay D; Petersen GM; Munzy DM; Fisher WE; Karim SA; Eshleman JR; Hruban RH; Pilarsky C; Morton JP; Sansom OJ; Scarpa A; Musgrove EA; Bailey UMH; Hofmann O; Sutherland RL; Wheeler DA; Gill AJ; Gibbs RA; Pearson JV; Waddell N, 2016, 'Genomic analyses identify molecular subtypes of pancreatic cancer', Nature, 531, pp. 47 - 52, http://dx.doi.org/10.1038/nature16965

Sabanathan D; Nagrial AM; Chin VT, 2016, 'The changing landscape of systemic therapy in advanced pancreatic cancer', Cancer Forum, 40, pp. 53 - 58

Gingras MC; Covington KR; Chang DK; Donehower LA; Gill AJ; Ittmann MM; Creighton CJ; Johns AL; Shinbrot E; Dewal N; Fisher WE; Pilarsky C; Grützmann R; Overman MJ; Jamieson NB; Van Buren G; Drummond J; Walker K; Hampton OA; Xi L; Muzny DM; Doddapaneni H; Lee SL; Bellair M; Hu J; Han Y; Dinh HH; Dahdouli M; Samra JS; Bailey P; Waddell N; Pearson JV; Harliwong I; Wang H; Aust D; Oien KA; Hruban RH; Hodges SE; McElhany A; Saengboonmee C; Duthie FR; Grimmond SM; Biankin AV; Wheeler DA; Gibbs RA; Jones MD; Mawson A; Scarlett CJ; Brancato MAL; Rowe SJ; Simpson SH; Smith Martyn M; Thomas MT; Chantrill LA; Chin VT; Angela C; Cowley MJ; Humphris JL; Mead S; Nagrial AM; Pajic M; Pettit J; Pinese M; Rooman I; Wu J; Tao J; DiPietro R; Watson C; Steinmann A; Lee HC; Wong R; Pinho AV; Giry-Laterriere M; Daly RJ; Musgrove EA; Sutherland RL; Kassahn KS; Miller DK; Wilson PJ; Patch AM; Song S; Idrisoglu S; Nourse C; Nourbakhsh E; Manning S; Wani S; Gongora M; Anderson M; Holmes O; Leonard C; Taylor D; Wood S; Xu C; Nones K; Fink LJ; Christ A; Bruxner T; Cloonan N; Newell F; Quinn M, 2016, 'Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation', Cell Reports, 14, pp. 907 - 919, http://dx.doi.org/10.1016/j.celrep.2015.12.005

Chou A; Steinmann A; Froio D; Drury A; Wohl D; Chin V; Nagrial A; Gill A; Pajic M, 2016, 'Combination of CDK4/6 inhibitor PD-0332991 with standard chemotherapy is synergistic in RB high pancreatic cancer', European Journal of Cancer, 61, pp. S182 - S182, http://dx.doi.org/10.1016/s0959-8049(16)61645-3

Nagrial AM; Chin VT; Sjoquist KM; Pajic M; Horvath LG; Biankin AV; Yip D, 2015, 'Second-line treatment in inoperable pancreatic adenocarcinoma: A systematic review and synthesis of all clinical trials', Critical Reviews in Oncology/Hematology, 96, pp. 483 - 497, http://dx.doi.org/10.1016/j.critrevonc.2015.07.007

Chantrill LA; Nagrial AM; Watson C; Johns AL; Martyn-Smith M; Simpson S; Mead S; Jones MD; Samra JS; Gill AJ; Watson N; Chin VT; Humphris JL; Chou A; Brown B; Morey A; Pajic M; Grimmond SM; Chang DK; Thomas D; Sebastian L; Sjoquist K; Yip S; Pavlakis N; Asghari R; Harvey S; Grimison P; Simes J; Biankin AV, 2015, 'Precision medicine for advanced pancreas cancer: The individualized molecular pancreatic cancer therapy (IMPaCT) Trial', Clinical Cancer Research, 21, pp. 2029 - 2037, http://dx.doi.org/10.1158/1078-0432.CCR-15-0426

Waddell N; Pajic M; Patch AM; Chang DK; Kassahn KS; Bailey P; Johns AL; Miller D; Nones K; Quek K; Quinn MCJ; Robertson AJ; Fadlullah MZH; Bruxner TJC; Christ AN; Harliwong I; Idrisoglu S; Manning S; Nourse C; Nourbakhsh E; Wani S; Wilson PJ; Markham E; Cloonan N; Anderson MJ; Fink JL; Holmes O; Kazakoff SH; Leonard C; Newell F; Poudel B; Song S; Taylor D; Waddell N; Wood S; Xu Q; Wu J; Pinese M; Cowley MJ; Lee HC; Jones MD; Nagrial AM; Humphris J; Chantrill LA; Chin V; Steinmann AM; Mawson A; Humphrey ES; Colvin EK; Chou A; Scarlett CJ; Pinho AV; Giry-Laterriere M; Rooman I; Samra JS; Kench JG; Pettitt JA; Merrett ND; Toon C; Epari K; Nguyen NQ; Barbour A; Zeps N; Jamieson NB; Graham JS; Niclou SP; Bjerkvig R; Grützmann R; Aust D; Hruban RH; Maitra A; Iacobuzio-Donahue CA; Wolfgang CL; Morgan RA; Lawlor RT; Corbo V; Bassi C; Falconi M; Zamboni G; Tortora G; Tempero MA; Gill AJ; Eshleman JR; Pilarsky C; Scarpa A; Musgrove EA; Pearson JV; Biankin AV; Grimmond SM, 2015, 'Whole genomes redefine the mutational landscape of pancreatic cancer', Nature, 518, pp. 495 - 501, http://dx.doi.org/10.1038/nature14169

Chin VT; Nagrial AM; Chou A; Biankin AV; Gill AJ; Timpson P; Pajic M, 2015, 'Rho-associated kinase signalling and the cancer microenvironment: Novel biological implications and therapeutic opportunities', Expert Reviews in Molecular Medicine, 17, http://dx.doi.org/10.1017/erm.2015.17

Pajic M; Herrmann D; Vennin C; Conway JRW; Chin VT; Johnsson AKE; Welch HCE; Timpson P, 2015, 'The dynamics of Rho GTPase signaling and implications for targeting cancer and the tumor microenvironment', Small GTPases, 6, pp. 123 - 133, http://dx.doi.org/10.4161/21541248.2014.973749

Humphris JL; Johns AL; Simpson SH; Cowley MJ; Pajic M; Chang DK; Nagrial AM; Chin VT; Chantrill LA; Pinese M; Mead RS; Gill AJ; Samra JS; Kench JG; Musgrove EA; Tucker KM; Spigelman AD; Waddell N; Grimmond SM; Biankin AV, 2014, 'Clinical and pathologic features of familial pancreatic cancer', Cancer, 120, pp. 3669 - 3675, http://dx.doi.org/10.1002/cncr.28863

Nagrial AM; Chang DK; Nguyen NQ; Johns AL; Chantrill LA; Humphris JL; Chin VT; Samra JS; Gill AJ; Pajic M; Pinese M; Colvin EK; Scarlett CJ; Chou A; Kench JG; Sutherland RL; Horvath LG; Biankin AV, 2014, 'Adjuvant chemotherapy in elderly patients with pancreatic cancer', British Journal of Cancer, 110, pp. 313 - 319, http://dx.doi.org/10.1038/bjc.2013.722

Sjoquist KM; Chin VT; Chantrill LA; O'Connor C; Hemmings C; Chang DK; Chou A; Pajic M; Johns AL; Nagrial AM; Biankin AV; Yip D, 2014, 'Personalising pancreas cancer treatment: When tissue is the issue', World Journal of Gastroenterology, 20, pp. 7849 - 7863, http://dx.doi.org/10.3748/wjg.v20.i24.7849

Chantrill L; Johns A; Nagrial A; Chin V; Chou A; Pinese M; Mead S; Gebski V; Sjoguist K; Lee C; Yip S; Miller D; Sebastian L; Asghari R; Harvey S; Paviakis N; Mukhedkar S; Grimison P; Miller D; Pearson J; Waddell N; Grimmond S; Simes J; Biankin A, 2013, 'The IMPaCT trial: Individualised Molecular Pancreatic Cancer Therapy. A pilot, randomized, open label Phase II trial assessing first line treatment with gemcitabine or personalized treatment based on tumour molecular signature in patients with metastatic pancreatic cancer.', MOLECULAR CANCER THERAPEUTICS, 12, http://dx.doi.org/10.1158/1535-7163.TARG-13-A75

Chou A; Waddell N; Cowley MJ; Gill AJ; Chang DK; Patch AM; Nones K; Wu J; Pinese M; Johns AL; Miller DK; Kassahn KS; Nagrial AM; Wasan H; Goldstein D; Toon CW; Chin V; Chantrill L; Humphris J; Mead RS; Rooman I; Samra JS; Pajic M; Musgrove EA; Pearson JV; Morey AL; Grimmond SM; Biankin AV, 2013, 'Clinical and molecular characterization of HER2 amplified-pancreatic cancer', Genome Medicine, 5, pp. 78, http://dx.doi.org/10.1186/gm482

Nagrial A; Chantrill L; Chin V; Sjoquist K; O'Connor CA; Yip D, 2013, 'Pharmacologic and radiotherapeutic interventions for advanced pancreatic cancer', Cochrane Database of Systematic Reviews, 2013, http://dx.doi.org/10.1002/14651858.CD010584

Chin VT; Nagrial A; Chantrill LA; Chang DK; Chou A; Humprhis J; Cowley M; Wu J; DiPetro R; Watson C; Spielman C; Steinmann A; Pinese M; Pettitt J; Johns A; Waddell N; Grimmond S; Timpson P; Biankin AV; Pajic M, 2013, 'From functional genomics to precision medicine: The therapeutic potential of targeting ROCK signaling in pancreatic cancer.', Journal of Clinical Oncology, 31, pp. e15029 - e15029, http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e15029

Chang DK; Jamieson N; Johns A; Scarlett CJ; Pajic M; Biankin AV; et A, 2013, 'Histomolecular phenotypes and outcome in adenocarcinoma of the ampulla of vater', Journal of Clinical Oncology, 31, pp. 1348 - 1356, http://dx.doi.org/10.1200/JCO.2012.46.8868

Chin VT; Waddell N; Nones K; Quek K; Mawson A; Johns A; Grimmond S; Biankin A, 2012, 'INDIVIDUALISED MEASUREMENT OF TUMOUR-DERIVED CIRCULATING DNA IN PATIENTS WITH PANCREATIC CANCER: A MARKER OF PROGNOSIS AND THERAPEUTIC RESPONSE', ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 8, pp. 36 - 36, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000306960100002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Biankin AV; Waddell NJ; Kassahn KS; Gingras M-C; Muthuswamy L; Johns AL; Miller DK; Wilson PJ; Patchett A-M; Wu J; Chang DK; Cowley MJ; Gardiner BB; Song S; Harliwong I; Idrisoglu S; Nourse C; Nourbakhsh E; Manning S; Wani S; Gongora MM; Pajic M; Scarlett CJ; Gill AJ; Pinho AV; Rooman I; Anderson ML; Holmes O; Leonard C; Taylor DF; Wood SA; Xu Q; Nones K; Fink JL; Christ A; Bruxner T; Cloonan N; Kolle G; Newell F; Pinese M; Mead RS; Humphris J; Kaplan W; Jones M; Colvin EK; Nagrial AM; Humphreys ES; Chou A; Chin VT; Chantrill LA; Mawson A; Samra JS; Kench JG; Lovell JA; Daly RJ; Merrett ND; Toon C; Epari K; Nguyen NQ; Barbour A; Zeps N; Kakkar N; Zhao F; Wu YQ; Wang MJ; Muzny DM; Fisher WE; Brunicardi FC; Hodges SE; Reid JG; Drummond J; Chang K; Han Y; Lewis LR; Dinh H; Buhay CJ; Beck T; Timms L; Sam M; Begley K; Brown A; Pai D; Panchal A; Buchner N; De Borja R; Denroche RE; Yung CK; Serra S; Onetto N; Mukhopadhyay D; Tsao M; Shaw PA; Petersen G; Gallinger S; Hruban R; Maitra A; Iacobuzio-donahue CA; Schulick RD; Wolfgang ; Morgan RA; Lawlor RT; Capelli P; Corbo V; Scardoni M; Tortora G; Tempero MA; Mann KM; Jenkins NA; Perez-Mancera PA; Adams DJ; Largaespada DA; Wessels LFA; Rust AG; Stein LD; Tuveson DA; Copeland NG; Musgrove EA; Scarpa A; Eshleman JR; Hudson TJ; Sutherland RL; Wheeler DA; Pearson JV; McPherson JD; Gibbs RA; Grimmond SM, 2012, 'Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes', Nature, 491, pp. 399 - 405, http://dx.doi.org/10.1038/nature11547

Humphris J; Chang D; Johns A; Scarlett C; Pajic M; Jones M; Colvin EK; Nagrial A; Chin V; Chantrill L; Samra JS; Gill A; Kench JG; Merrett ND; Das A; Musgrove EA; Sutherland RL; Biankin AV, 2012, 'The prognostic and predictive value of serum CA19.9 in pancreatic cancer', Annals of Oncology, 23, pp. 1713 - 1722, http://dx.doi.org/10.1093/annonc/mdr561

Yip D; Karapetis C; Strickland C; Steer C; Goldstein D, 2006, 'Chemotherapy and radiotherapy for pancreatic cancer', Cochrane Database of Systematic Reviews, 4

Teague BD; Morrison CP; Court FG; Chin VT; Costello SP; Kirkwood ID; Maddern GJ, 2004, 'Role of FDG-PET in surgical management of patients with colorectal liver metastases', ANZ Journal of Surgery, 74, pp. 646 - 652, http://dx.doi.org/10.1111/j.1445-1433.2004.02948.x

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