Dr Valencia Arroyo (MD, MSc, PhD) is an infectious diseases physician and emerging research leader in human immunogenetics, with extensive background experience (>12 yrs) in clinical research and a recent PhD studying host and pathogen determinants of infectious diseases outcomes incorporating whole genome viral sequencing, genome-wide association studies (GWAS) and genome-to-genome analyses. He also acquired complementary bioinformatics and genomics skills training in Genomic data science (John Hopkins University), Next Generation Sequencing Bioinformatics (The European Bioinformatics Institute), and Genomics and Clinical Virology (Wellcome Genome Campus, Cambridge). In the first year post-PhD, Dr Valencia Arroyo has an i-index = 15, FWCI = 2.18, and 38 publications of collaborations with 132 researchers worldwide; 36% of the papers are in the top 10% most cited. He currently leads the host immunogenetics arm of the Viral Immunology Systems Program (VISP), which investigates globally significant infectious diseases (dengue, hepatitis C, SARS CoV-2). Dr Valencia Arroyo is a member of the Executive Committee of COFFI, the international consortium supporting this proposal with 19 prospective cohorts following subjects from acute infective illness up to 6-12 months after infection. He has participated as an expert in two World Health Organization technical reports in HTLV-1 (ISBN: 978-92-4-002022-1) and American Tegumentary Leishmaniasis (ISBN: 978-92-75-32191-1), as well as a book chapter on neurological infections (10.1016/B978-0-444-53490-3.00013-3). Dr Valencia Arroyo is an active peer reviewer for over 18 scientific journals (54 peer-reviews) and an infectious diseases officer at the Public Health Unit (South Eastern Sydney Local Health District), supporting outbreak containment activities and case investigations. To date, his research has attracted >$340K in competitive grant funding, including a prestigious Scientia scholarship and a global UNSW initiative to retain outstanding researchers.