Researcher

Dr Kevin Ni

My Expertise

My expertise is in cancer biology and biomarker discovery, involving all stages of the translational pipeline, encompassing basic and clinical research on understanding how cancer starts, develops, spreads and identifying novel diagnostic and therapeutic biomarkers for particularly prostate, breast and bladder cancers. My research outputs are extensive as evidenced by > 40 publications with a high number of citations (h-index=24, total google citation=2300) and impact (FWCI=3.19), which have significantly informed precision medicine across the urological and breast cancer control continuum of early detection, diagnosis, treatment and surveillance. I also have extensive experience in the preparation and reviewing of human research ethics applications and promoting the good clinical practice in clinical trials/research across all health disciplines.

 

Keywords

Fields of Research (FoR)

Cancer Cell Biology, Chemotherapy, Radiation Therapy, Cancer Diagnosis, Biological and Medical Chemistry, Oncology and Carcinogenesis, Protein Targeting and Signal Transduction, Medical and Health Sciences, Cancer Diagnosis

Biography

I am a cancer research scientist specialising in molecular biomarker discovery, liquid biopsy and extracellular vesicles, transcriptomics, chemo-/radio-resistance, radiation biology, cancer stem cell and imaging in prostate, breast and bladder cancers.

I am currently a Senior Scientific Officer in Cancer Services at St George Hospital SESLHD and Conjoint Senior Lecturer in School of Clinical Medicine, Faculty of Medicine and Health, based on...view more

I am a cancer research scientist specialising in molecular biomarker discovery, liquid biopsy and extracellular vesicles, transcriptomics, chemo-/radio-resistance, radiation biology, cancer stem cell and imaging in prostate, breast and bladder cancers.

I am currently a Senior Scientific Officer in Cancer Services at St George Hospital SESLHD and Conjoint Senior Lecturer in School of Clinical Medicine, Faculty of Medicine and Health, based on St George and Sutherland Clinical Campuses.

I obtained my BA and MBBS/MD degrees from China in 2011 and completed my PhD at UNSW Sydney in 2016. To date, I have authored more than 40 publications in peer-reviewed journals which have attracted more than 2,200 citations with an h-index of 25.

Selected Professional & Editorial Activities

  • Contracted Scientific Reviewer, Research Directorate, SESLHD (2021~)
  • Member, Human Research Ethics Committee, SESLHD (2021~)
  • Member, Work Health & Safety Committee, STGCL UNSW (2016~)
  • Member, Peer-Review Taskforce, Postgraduate Scholarships, NHMRC (2020~)
  • Member, Peer-Review Committee, e-Asia joint program, NHMRC (2019)
  • Executive Committee Member, Australian Association for Chinese Biomedical Scientists (2011~)
  • Member, American Association for Cancer Research (2013~)
  • Member, European Association for Cancer Research (2017~)
  • Member, European Society of Medical Oncology (2017~)
  • Associate Editor/Editorial Board Member, Board of Radiation Oncology, Frontiers in Oncology (2020~)
  • Editorial Board Member, Journal of Extracellular Vesicles (2020~)

My Grants

  • CIA: A novel liquid biopsy assay of blood exosomal microRNA profiles to improve prostate cancer diagnosis. St George and Sutherland Medical Research Foundation, A$46,000, 2021-2022;
  • AI: Combining nanoplasmonic profiling with machine learning for non-invasive early detection of ovarian cancer using plasma exosomes, Ovarian Cancer Research Foundation (GA-2019-13), A$134,026, 2020-2021.
  • CI: Validation of extracellular vesicle protein biomarkers in blood for the personalised treatment decision of prostate cancer patients. SSMRF-St George Cancer Care Foundation Award, A$50,000, 2022-2023.

My Qualifications

  • Bachelor of Arts
  • Bachelor of Medicine, Bachelor of Surgery
  • Doctor of Medicine
  • Doctor of Philosophy

My Awards

  • National Scholarship of Excellence, 2008;
  • Outstanding Graduate, 2011;
  • Prostate and Breast Cancer Foundation Scholarships, 2012-2015;
  • Outstanding Self-financed Students Abroad Award of China, 2013;
  • Best oral presentation in Basic Science, 2nd Prize, St George and Sutherland Medical Research Symposium, 2016;
  • Travel grant award, European Society for Medical Oncology (ESMO) Asia 2017 Congress, 2017;
  • Service Excellence Award, AACBS, 2018.

My Research Activities

Dr Ni's current research interests are

  • identification of biomarkers in liquid biopsy (exosomes) on early detection and prognostic evaluation of prostate cancer patients;
  • proteomic and transcriptomic identification of novel biomarkers to predict radio-resistance in breast and prostate cancers;
  • investigation of the mechanisms of cancer progression, metastasis and therapeutic resistance associated with tumour microenvironment and cancer stem cells;
  • clinicopathologic and biomarker predictors for bladder cancer diagnosis, prognosis and surveillance.

My Research Supervision


Supervision keywords


Areas of supervision

I have supervised and co-supervised two PhDs and four Honours/ILP students to completion. I am available (upon agreement) to supervise and co-supervise PhD and ILP/Honours students in areas of liquid biopsy, tumour biology, molecular biology, biomarker discovery, radiation oncology, prostate cancer, cancer stem cells and radio-/chemo-resistance. Both lab-based and clinical studies are available in collaboration with clinicians.

Lab Alumni

Dr Xupeng Bai, PhD student, 2017-2021, with Dean's award, currently Research Fellow/Assistant Professor, Zhejiang University, China (co-supervisor)

Dr Bairen Pang, PhD student, 2017-2022 (co-supervisor)

Evan Cheng, ILP student, 2018 (co-supervisor)

Grace Tang, ILP student, 2018 (co-supervisor)

Jingpu Wang, ILP student, 2019 (primary supervisor)

Dylan Tsao Tsing, Honours student, 2019 (co-supervisor)

Nitin Niranjan, ILP student, 2019 (co-supervisor)


Currently supervising

  • PhD students 2x (EV transcriptomics and metabolomics in prostate cancer)
  • Masters Student 1x (EV proteomics in breast cancer)
  • Hons students 1x (primary supervisor, with peer-reviewed publication, EV miRNAs in bladder cancer)
  • Incoming Hons student Year 2023 2x (EV and MRI in prostate and bladder cancers)

My Engagement

https://www.theleader.com.au/story/5759719/scientists-pave-the-way-forward-with-medical-research/

St George Hospital cancer researchers work to advance benefits for patients through early detection

View less

Location

Level 2, Research and Education Centre, St George Hospital, 4-10 South Street, KOGARAH NSW 2217

Map reference (Google map)

Contact

(02) 9113 4049