Dr. Lili Song MD PhD, is the Head of Stroke Program, senior research fellow at The George Institute for Global Health (TGI), and senior lecturer at Faculty of Medicine, University of New South Wales. She has been a neurologist for 15 years and focused on clinical research for more than 10 years. Her research interest is in the treatment and prevention of acute stroke, in particular of blood pressure management and digital management platform...view more
Dr. Lili Song MD PhD, is the Head of Stroke Program, senior research fellow at The George Institute for Global Health (TGI), and senior lecturer at Faculty of Medicine, University of New South Wales. She has been a neurologist for 15 years and focused on clinical research for more than 10 years. Her research interest is in the treatment and prevention of acute stroke, in particular of blood pressure management and digital management platform after stroke. She currently leads several large-scale clinical trials in stroke area including INTERACT3, INTERACT4, ENCHANTED-MT, Late-MT, CHAIN and ASPIRING as co-PI, co-investigator, Project lead as well as Steering Committee and Executive Committee members. She serves Steering Committee or Data Safety Monitoring Board members for several other large clinical trials (TRIDENT, OPTIMISTmain, PROTECT-MT, and ENRICH-AF). She has successfully awarded as CIB an MRC joint funding in the UK in 2019 as well as an MRFF funding in Australia in 2022. She has published more than 50 publications on high impact clinical journals including NEJM and Lancet (2 Lancet paper as co-first author). She is a reviewer for many high-ranking clinical journals including Lancet, Stroke, Cerebrovascular Diseases, International Journal of Stroke, European Stroke Journal, SVN, TRIALS, etc. She was invited to write editorial or commentary for Lancet Neurology and JAMA. She is supervising 2 PhD students at UNSW. She has been identified as one of 2018 Emerging Leaders by the World Heart Foundation.
My Grants
- The third, Intensive care bundle with blood pressure reduction in acute cerebral haemorrhage (INTERACT3) trial. Co-investigator (second), GBP 2,280,496, 2020-03-01 to 2023-02-28, JGHT-CALL 9: DFID/MRC/NIHR/Wellcome Trust Joint Global Health Trials (MR/T005009/1)
- The Second Enhanced Control of Hypertension and Thrombectomy Stroke Study (ENCHANTED2). Co-investigator (CIB) and Project Lead. MRFF International Clinical Trial Collaborations - ICTC 21-1 (APP2015371) AUD 2,029,361, 2022-2025, 2021
- INTEnsive blood pressure Reduction in hyperAcute Cerebral haemorrhage Trial. First author, AUD 50,000, 2018/19 Seed Grant: Under-Served Populations in LMIC, The George Institute for Global Health
- Screening, Early referral and Lifestyle tailored E_prescription for Cardiovascular prevention in PakisTan (SELECT): a pilot feasibility study. Co-author, AUD 49,940, 2018/19 Seed Grant: Under-Served Populations in LMIC, The George Institute for Global Health
- Essential Acute Stroke care in low resource settings : a pilot studY (EASY) Co-author, USD 25,000, 2018/19 Seed Grant, the World Heart Federation
My Qualifications
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Institution
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Qualification
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Date Awarded
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Department of Neurology; Changzheng Hospital
The Second Military Medical University, Shanghai, China
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PhD
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2004
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Department of Aerospace Clinical Medicine
School of Aerospace Medicine
The Fourth Military Medical University, Xi’an, China
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Master of Medical Science
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2001
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The Fourth Military Medical University, Xi’an, China
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Bachelor of Medical Science
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1998
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My Awards
- I am Head of Stroke Program at TGI, China. I am responsible for obtaining funding and setting budgets across my team, managing staff, supervising researchers, and making strategic priority.
- I am a member of Stroke Academic Work Committee, Chinses Geriatrics Society. We meet regularly to establish network and collaboration, disseminate knowledge and evidence with the commission of improving the health in elder population.
- I was identified by the World Heart Federation as an emerging leader of great potential (2018). I was also awarded a seed grant as co-PI by WHF.
- I regularly review manuscripts for several scientific journals including Lancet, Stroke, Cerebrovascular Diseases, International Journal of Stroke, Stroke and Vascular Neurology, Trials, Frontiers in Neurology, etc.
- I have co-authored invited Reviews for Stroke (IF:10.17), International Journal of Stroke (IF: 6.948, corresponding author).
- I have co-authored invited Comment for Lancet Neurology (IF 59.935).
- I have co-authored invited Editorials for JAMA (IF:56.272).
- I have been invited to be Editorial Board member for Cerebrovascular Diseases from 2023.
- I was invited to review abstracts for International Stroke Conference (2020-2022); and review the research grant application for Faculty of Medicine, Zhejiang University (2019).
- I was invited to be PhD Recruitment Interview Committee member for Guangdong Province TCM Hospital (2022).
- My clinical trial expertise has been recognised in my being invited to be a Data Safety Monitoring Board member for a China multicentre trial (PROTECT-MT), and was invited to sit on the Steering Committee for several international trials (ENRICH-AF, TRIDENT, ASPIRING, OPTIMISTmain).
- Recognition at the George Institute: sitting on TGI China Research Operation and Strategy Committee and Impact & Engagement Advisory Group. In these roles, I engaged in facilitation of achieving 2025 strategy and how to incorporate global strategy into China office. I am also the China coordinator for Better Treatment – one of three 2025 institutional strategy. As the coordinator, I act as a bridge to develop the collaborations between regions and offices.
My Research Activities
My research experience has encompassed many fields, including electrophysiology, animal behaviour, molecular biology and clinical trials. My master’s dissertation study focused on “Effects of pHo on membrane potential and K+ channels’ activity in aortic smooth muscle cells”. My PhD research was “Effect of diabetes mellitus on cognition of vascular dementia”, in which many basic medical research techniques such as cell culture, patch-clamp, making animal model, molecular biology were mastered and developed.
I started engaging in clinical trials and epidemiological research over the last ten years. At the beginning I worked as the medical monitor for the ENCHANTED and BEYOND7 studies, and as an end-point adjudicator for SAVE, all of which were undertaken by The George Institute and George Clinical organisations. I also worked as the Lead of the central follow-up team and study coordinator for HeadPoST study in China, resulting in a New England Journal of Medicine publication. While staying in the previous hospital, I played the role of site PI of ENCHANTED and HeadPoST study.
Current contribution to the field of research:
- CIB, Steering Committee member and global Project Lead of MRC-jointly-funded The third, INTEnsive care bundle with blood pressure Reduction in Acute Cerebral haemorrhage Trial (INTERACT3, completed).
- Recruited 7000+ stroke patients, 121 centres, 10 countries.
- The main result has been published on Lancet in May, 2023 (co-first author).
- CIB and Project Lead, SC member of Second Enhanced Control of Hypertension and Thrombectomy Stroke Study (ENCHANTED2-Part A).
- Recruited 816 stroke patients, 45 centres in China.
- The main result has been published on Lancet in Oct, 2022 (co-first author).
- Co-PI and Project Lead of ongoing INTEnsive blood pressure Reduction in hyperAcute Cerebral haemorrhage Trial (INTERACT4).
- Recruited 2300+ stroke patients, 50+ centres in China.
- Co-investigator and Project Lead, SC member of Chinese Herbal medicine in Acute Intracerebral haemorrhage (CHAIN) trial.
- Recruited 1300+ stroke patients, 28 centres in China.
- Co-investigator and project lead of Large Artery occlusion Treated in Extended Time with Mechanical Thrombectomy (LATE-MT) trial.
- Anticipated recruitment of 300+ stroke patients, 30+ centres in China.
- Co-invistigator and Steering Committee member of ASPIRING Pilot Trial.
- Recruitment completion of 80 stroke patients, 20+ centres in China and Australia.
- Co-PI of ongoing WHF-funded Essential Acute Stroke care in low resource settings: a pilot studY (EASY).
- Steering Committee member of TRIDENT, ENRICH-AF, OPTIMISTmain, INTERACT3, INTERACT4, ENCHANTED2, CHAIN, ASPIRING, EASY trials.
- Data Safety Monitoring Board member for PROximal TEmporary oCclusion using balloon guide caTheter for Mechanical Thrombectomy (PROTECT-MT) trial.
- Supervision of 3 PhD students at UNSW.
- Regular peer review for several scientific journals including Lancet, Stroke, European Stroke Journal, Cerebrovascular Diseases, International Journal of Stroke, Stroke and Vascular Neurology, Trials, Frontiers in Neurology, etc.
- I was invited to review abstracts for International Stroke Conference (ISC, 2020-2022), and World Intracerebral Haemorrhage Conference (WICH, 2023); and review the research grant application for Faculty of Medicine, Zhejiang University (2019).
My Research Supervision
Supervision keywords
Areas of supervision
I prefer to supervise students who are interested in clinical research, particularly clinical trials. The areas includes comprehensive management in patients with acute intracerebral heamorrhage; blood pressure control as secondary prevention in patients with ICH; pre-hospital management in acute suspected stroke patients.
Currently supervising
I am co-supervising 2 PhD student with Professor Craig Anderson.
My Teaching
My post teaching experience:
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Supervision for junior medical resident officers (2 completed Doctor of Medicine).
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Responsible for clinical tutorials for 5th year medical students in my role as Head of teaching and research section for internal medicine since 2014
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I have tutored a master student, Dr Wu Yujun, as an advisory teacher in his research topic and paper writing during 2011-2013.
https://orcid.org/0000-0002-6105-1720