My Expertise
The management of rhinologic and skull base disorders is a field that is continuously evolving, with patient diagnostic tools and treatment approaches varying greatly between clinicians across the world. Our research group, lead by Prof Richard Harvey and of which I am director of clinical research, comprises investigators at different stages of their medical or scientific careers in the fields of rhinology, endocrinology, immunology and neurosurgery.
We endeavour to:
1) investigate the usefulness of applying diagnostic methodologies, often considered research tools only, in the clinical setting;
2) expand our understanding behind the mechanisms driving these types of disorders; and
3) assess the use of novel treatment options in their management.
We do so by conducting studies that evaluate the effectiveness of what is currently applied by specialists in these fields and conducting clinical trials that investigate novel disease management options. Our goal is to optimise the current approach in the diagnosis and treatment of rhinologic and skull base disorders in real life clinical settings with a more personalised medicine purpose.
Keywords
Fields of Research (FoR)
Immunology, Clinical sciences, Otorhinolaryngology, Respiratory diseasesSEO tags
Biography
As Director of clinical research of our group, I coordinate the investigation of novel diagnostic and treatment options in the management of rhinologic and skull base disorders in real life clinical settings.
For more than 10 years I have been the Director of Clinical Research of the Rhinology and Skull Base Research Group (lead by Prof Richard Harvey) of the St Vincent's Centre for Applied Medical Research. As well, I am a senior upper...view more
As Director of clinical research of our group, I coordinate the investigation of novel diagnostic and treatment options in the management of rhinologic and skull base disorders in real life clinical settings.
For more than 10 years I have been the Director of Clinical Research of the Rhinology and Skull Base Research Group (lead by Prof Richard Harvey) of the St Vincent's Centre for Applied Medical Research. As well, I am a senior upper airways scientist at a tertiary rhinology practice.
I have also worked as a casual academic being involved in teaching of practical and tutorials as well as lecturing across disciplines of immunology, haematology, microscopy and cytometry. I have been involved in development of course materials for a research inspired, collaborative immunology curriculum. As a conjoint Senior Lecturer of the University of NSW I have co- supervised ILP and Honours UNSW undergraduate students as well contributed in the supervision of UNSW and MHU PhD candidates. I have authored over 65 peer reviewed publications (with a H-index of 23) and have presented at national and international conferences. I have also been invited to participate as guest lecturer, and have been a member of faculty/coordinated professional development courses, that enable further training of otolaryngologists, respiratory physicians, immunologists, allergists and GP’s.
My Grants
In my role I have collaborated with pharmacological companies for industry sponsored studies (SYNAPSE study – GSK/ The effect of Betamethasone Dipropionate on patients with eosinophilic Chronic Rhinosinusitis – Oticara).
I have also contributed in the application and management of educational grants to the rhinology research group trust fund (used for research projects associated to UNSW) and coordination with industry (e.g. medication donation for study REGIS ID 2019/PID04424 by GSK and Sanofi, for study REGIS ID 2021/PID02338 by Stallergenes and for study REGIS ID 2025/PID01744 by P&G).
Competitive grant applications (NHMRC 2017, St Vincent’s Clinic & Curran 2021).
My Qualifications
Bachelor of Science in Biomedical Science (with AIMS accreditation), Honours (First Class), Doctor of Philosophy (PhD) in Immunology, Parasitology
My Research Activities
Our research group, lead by Prof Richard Harvey, is actively involved in tertiary research at all levels of medical and surgical rhinologic and skull base care. Our projects involve both international collaborations, and multi-centre studies within Australia.
Our current studies include:
Effects of biologic medications in airway disease (CRS, eCRS, Type 2 inflammation)
Diagnostic treatment protocols for rhinitis, sinusitis and tumours
Novel topical therapies in CRS management
Diagnosis and interventions for the perception of nasal obstruction
Clinical outcomes in skull base surgery
Pituitary tumour genetics, diagnosis, treatment and surgery
Outcomes assessment for open rhinoplasty and endoscopic turbinate reduction
Basic and clinical science to the etiopathogenesis of CRS
A tissue bank program allowing a range of other research projects
If you would like more information about our research, or are interested in becoming involved in any of our projects please contact us on +61 2 9360 4811 or noselab@sydneyentclinic.com. We conduct our research meetings on alternate Wednesdays from 5:30pm in the Level 8 conference room at St Vincent’s Centre for Applied Medical Research (AMR), entrance at 405 Liverpool St. If you would like to attend, please contact us ahead of time so that we can coordinate access (if entering the building after 5pm, you will need swipe access to get in the front doors and also up the lift). For OH&S reasons, if you do not have a SVMHS swipe card, you must sign in to the AMR visitor book.
Location
Clinical Unit: 67 Burton St, Darlinghurst, NSW 2010
Map reference (Google map)
Contact
Publications
ORCID as entered in ROS
https://orcid.org/0000-0001-7250-2200