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Researcher

Dr Sean O'Donoghue

Fields of Research (FoR)

Bioinformatics, Structural Biology (incl. Macromolecular Modelling), Systems Biology

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Biography

Seán O’Donoghue is a Conjoint Professor at the School of Biotechnology and Biomolecular Science (BABS), University of New South Wales. He also is a Laboratory Head and Senior Faculty Member at the Garvan Institute of Medical Research in Sydney, and a Visiting Scientist at CSIRO Data61.

He received his B.Sc. (Hons) and PhD in biophysics from the University of Sydney, Australia. Much of his career was spent in Heidelberg, Germany, where he...view more

Seán O’Donoghue is a Conjoint Professor at the School of Biotechnology and Biomolecular Science (BABS), University of New South Wales. He also is a Laboratory Head and Senior Faculty Member at the Garvan Institute of Medical Research in Sydney, and a Visiting Scientist at CSIRO Data61.

He received his B.Sc. (Hons) and PhD in biophysics from the University of Sydney, Australia. Much of his career was spent in Heidelberg, Germany, where he worked in the Structural and Computational Biology programme at the European Molecular Biology Laboratory (EMBL), and at Lion Bioscience AG - then the world's largest bioinformatics company - where he was Director of Scientific Visualization.

He has been actively engaged in bioinformatics research since 1988. He contributed to the development of ARIA, a method widely used for calculating 3D structures from NMR data. Since then, he has initiated and is leading the development of several computational resources that use data visualization, graphic design, and user interface principles to simplify the discovery of insight from complex biological data. These resources are focused on structural biology, systems biology, and sequence analysis. He is also co-founder and leader of two initiatives: VIZBI, an international initiative aimed at improving data visualization in bioinformatics software, and VizbiPlus, aimed at educating and inspiring the general public about cutting-edge biomedical research.

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Location

Garvan Institute of Medical Research

Map reference (Google map)

Contact

+61 2 9325 3278

Videos

How healthy diet and gut bacteria help prevent cancer. Created by Christopher Hammang (CSIRO, Sydney).
Reveals the role of protein breakdown in Alzheimer’s disease. Created by Christopher Hammang (CSIRO, Sydney).
How molecular mistakes can now be detected in individual cancers. Created by Kate Patterson (Garvan Institute of Medical Research, Sydney).
How methylation can affect gene expression without changing the genetic code. Created by Kate Patterson (Garvan Institute of Medical Research, Sydney).
The Hungry Microbiome
Alzheimer's Enigma
Cancer Is Not One Disease
Tagging DNA: Mislabelling The Cancer Genome