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Researcher

Dr Yue Huang

My Expertise

My expertise is in research related to neurogenetic disorders, such as Huntington's disease, Parkinson's disease, Alzheimer's disease, etc, via clinical and pathological approaches. My research area mainly relates to 1) Study of gut-brain axis in neurodegenerative diseases; 2) Genetic & pathological diagnosis and clinical management of rare brain diseases;  3) Investigating changes in the tissue microenvironment leading to pathological inclusion body formation; and 4) Promoting brain health and neuroprotection against neurodegeneration.

Keywords

Fields of Research (FoR)

Developmental Psychology and Ageing, Health, Clinical and Counselling Psychology, Central Nervous System, Pathology

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Biography

I obtained MBBS degree from Harbin Medical University, China in 1991, trained as a neurologist, and practiced in clinics for nine years. I started my medical research career in 2003, when I completed my PhD in genetic and proteomic studies on neurological conditions. Following my PhD, I had postdoctoral training on neuropathology at Neuroscience Research Australia in Sydney, Australia. I became a conjunct Lecturer and Senior Research Officer...view more

I obtained MBBS degree from Harbin Medical University, China in 1991, trained as a neurologist, and practiced in clinics for nine years. I started my medical research career in 2003, when I completed my PhD in genetic and proteomic studies on neurological conditions. Following my PhD, I had postdoctoral training on neuropathology at Neuroscience Research Australia in Sydney, Australia. I became a conjunct Lecturer and Senior Research Officer in January 2008, a conjoint senior lecturer and associate professor of the University of New South Wales, Australia, in 2012 and 2016. I took the position of Director, Human Brain & Tissue Bank at China National Clinical Research Centre for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, China in Dec. 2017. I set up longitudinal observation cohorts for various neurological disorders, particularly in monogenetic form. I spend 30% of my time on outpatient and research clinics, 30% on pathological classification of incoming brain tissues, 30% on medical research and 10% on teaching. I have over 100 peer reviewed publications with H index 32 in my career and over 30 publications in the past five years. I have built up resources to support high impact research published in Cell, Neuron and Science Advance (2023).

(updated on Feb.2004)


My Grants

1. Investigating liquid-liquid phase separation involved in P62 condense in Chinese specific brain organoids and animal models of Alzheimer's disease. 2023.06-2025.06

2. Co-morbidities of Heart and Brain - Provincial Collaborative Innovation Center for Prevention and Control of Major Cardiovascular Diseases, Capital Medical University, China, 2022.04-2023.04

3. Clinical evaluation of the accuracy of RT-QuIC for the diagnosis of alpha-synucleinopathies, ID: 2022SKLID306, State Key Laboratory of Infectious Disease Prevention and Control, China, 2022.06-2023.06

4. Brain Health Management of Living Donors, National Human Body, Tissue and Organ Donation Management Center, China, 2021.08-2022.12

5. Exploring the mechanism and clinical application of cellular exocytosis vesicles on the progression of alpha-synucleinopathies. National Natural Program of China, ID: 82071417, 2021.01-2024.12

6. Enrol GBA gene mutants in China, YiCheng Fundation, China, 2022.12-2023.12

7. Enrol HD in China, Beijing Tiantan Hospital, Capital Medical University, China, 2018.12-2023.12

8. Human Brain Banking, Beijing Tiantan Hospital, Capital Medical University, China, 2017.12-2022.12


My Qualifications

MBBS, Harbin Medical University, Harbin, China

MD, Harbin Medical University, Harbin, China

PhD, Harbin Medical University, Harbin, China & Capital Medical University, Beijing, China & Flinders University, Australia

GCULT, The University of New South Wales, Sydney, Australia


My Research Supervision


Supervision keywords


Areas of supervision

I am available to supervise HDR Candidates if they would like to conduct data based analysis and bioinformatics research on Parkinson's disease and in Alzheimer's disease. For laboratory based projects, I am available to co-supervise to provide my expertise to HDR based in Sydney. Alternatively, if the HDR would be able to conduct the experiemnts in Beijing, the laboratory based projects are also doable.


Currently supervising

Ph.D students, MD students and Postdoc with location in Beijing Tiantan Hospital, Capital Medical University, Beijing, China

 


My Engagement

1. Australia and New Zealand Neurologists and Neuropathologists Association

2. Member of International Parkinson and Movement Disorders Society 

3. Member of the Neuropathology Group of the Chinese Society of Neurology

4. Member of the Special Committee of the Neurodegenerative Diseases Branch of the Chinese Society of Microcirculation

5. Member of the 5th Chinese Society of Gerontology and Geriatrics, Geriatrics Branch, Geriatric Neurology Committee

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