Keywords
Biography
Dr.Murat Dogru is the first academician from the whole continental Europe to acquire a Japanese Medical License to practice in the field of Ophthalmology. Dr. Murat Dogru is an internationally recognized expert in ocular surface disorders, dry eyes, ocular allergy and ocular inflammation. He conducts both basic and translational research in the field of corneal and ocular surface inflammation and oxidative stress. He studies the molecular and...view more
Dr.Murat Dogru is the first academician from the whole continental Europe to acquire a Japanese Medical License to practice in the field of Ophthalmology. Dr. Murat Dogru is an internationally recognized expert in ocular surface disorders, dry eyes, ocular allergy and ocular inflammation. He conducts both basic and translational research in the field of corneal and ocular surface inflammation and oxidative stress. He studies the molecular and cellular mechanisms of ocular inflammation with applications to autoimmunity, dry eye disease, contact lens wear and ocular allergy.
An executive board member of the international Tear film and Ocular Surface Society, Asia Dry Eye Society and Japan Dry Eye Research Society, and a Fellow of the Association for Research in Vision and Ophthalmology (ARVO), he has authored more than 283 peer-reviewed articles and several book chapters, and has presented more than 200 invited and named lectures worldwide. His published work has been read and cited more than 8,200 times. Dr. Dogru’s research has led to several successful grant applications to the Japanese Ministry of Health and the Japan Society for the Promotion of Science where he was registered as an official researcher of Japan in 2002. His research is also supported by several continual industry grants. Dr. Dogru has trained several clinical fellows, postdoctoral fellows and students in Turkey and in Japan over 8 countries to date, the significant majority achieving full-time academic positions in ophthalmology and vision research in their respective countries. Dr. Dogru served as a lecturer for Kobe School of Optometry from 1995-1999 and established a teaching and wet lab curriculum for corneal topography, contact lens wear and adverse effects with Johnson and Johnson in Japan for Japanese Ophthalmology residents and optometrists for the first time.Dr. Murat Dogru currently is a practicing ophthalmologist and a researcher affiliated with Keio University School of Medicine, Tokyo, Japan and Tsurumi University Eye Clinic,Yokohama, Japan
My Grants
Government Grants
Japanese Ministry of Health Grant 2005-2007 Grant amount: 20.000.000 JY Title: Preparation of World Dry Eye Diagnostic Guidelines and Introduction of Guidelines into Japan
Japan Society for Promotion of Science 2009-2011 Grant amount: 3.500.000 JY Title: Evaluation of the lacrimal gland/Ocular surface damage mechanism due to smoking
Japan Society for Promotion of Science 2009-2011 Grant amount: 3.500.000 JY Title:：Investigation of epithelial-mesenchymal differentiation in the aging dry eye SOD1 KO mouse
Japan Society for Promotion of Science 2010-2011 Grant amount: 2.200.000 JY Title: Pathophsiology of Age related Meibomian gland disease
Japan Society for Promotion of Science2011 Grant amount: 3.500.000 JY Title:：Evaluation of the lacrimal gland/Ocular surface damage mechanism due to smoking
Industry Grants
2006 Johnson & Johnson Ocular Surface and Visual Optics Sponsored Department Grant amount: 40.000.000 JY
2007 Johnson & Johnson Ocular Surface and Visual Optics Sponsored Department Grant amount: 40.000.000 JY
2008 Johnson & Johnson Ocular Surface and Visual Optics Sponsored Department Grant amount: 40.000.000 JY
2009 Johnson & Johnson Ocular Surface and Visual Optics Sponsored Department Grant amount: 30.000.000 JY
2010 Johnson & Johnson Ocular Surface and Visual Optics Sponsored Department Grant amount: 30.000.000 JY
2011 Santen Pharmaceuticals Basic investigation on the administration of 3% Diquafosol sodium eye drops in the SOD 1 KO dry eye model mice Grant amount:1.000.000 JY
Otsuka Pharmaceuticals The effect of rebamipide eye drops on inflammatory cytokines in the SOD1 KO mice Grant amount: 15.000.000 JY
2012 Otsuka Pharmaceuticals The effect of rebamipide eye drops on inflammatory cytokines in the SOD1 KO mice Grant amount: 22.000.000 JY
2014 Otsuka Pharmaceuticals The effect of rebamipide eye drops on inflammatory cytokines in the SOD1 KO mice Grant amount: 4.920.000 JY
2015 Otsuka Pharmaceuticals The effect of rebamipide eye drops on inflammatory cytokines in the SOD1 KO mice Grant amount: 6.730.000 JY
2016 Santen Pharmaceuticals The effect of 3% Diquafosol sodium eye drops on dry eyes induced by anti-glaucoma medications Grant amount: 4.500.000 JY
2017 Santen Pharmaceuticals The effect of 3% Diquafosol sodium eye dropson membrane mucins in an age related dry eye mouse model Grant amount: 1.500.000 JY
Otsuka Pharmaceuticals The nerve protection effects of rebamipide eye drops in environmental stress dry eye mouse models Grant amount: 8.140.000 JY
Eco Denki Co The in vitro applicability of strip meniscometry tubes Grant amount: 3.500.000 JY
Otsuka Pharmaceuticals Evaluation of the retrieaval of antioxidantsin a dry eye model mouse Grant amount: 4.950.000 JY
2018~2023
Icom Inc,The ocular surface effects and bioavalibility of novel dry eye, ocular allergy and anti-glaucoma eye frops Grant amount:50.000 Euro/year
My Qualifications
Language Skills
- Turkish Native
- English Fluent
- Japanese Fluent
- German Fluent
Licences
Doctor of Medicine MD 89AB053 Granted by Turkish Ministry of Health on June 30 1989
Doctor of Medicine MD 8944 Granted by Japan Ministry of Health on April 19 2013
Ophthalmology specialist 1993
Associate Professorship in Ophthalmology 2002 (Turkey) 2006 (Japan)
Doctorate Degree
PhD obtained from Kobe University School of Medicine (HAKU-I-1218)
Field: Corneal science
PhD Thesis paper：Impression Cytology in Atopic Dermatitis, Ophthalmology 1998
Memberships in Professional Societies
Turkish Ophthalmology Society
Turkish Cornea Society Executive Member
Japanese Ophthalmological Society
Japan Cornea Society
Kyoto Cornea Club
ARVO
Tear Film Ocular Surface Society (Execuitive Board Member)
Turkish Contact Lens Society
Japan Dry Eye Society (Executive Board Member)
Asia Dry Eye Society (Board Member)
Editorial Board Member
IOVS
Eye and Contact Lens (ECLA-former CLAO journal)
Turkish Ophthalmology Journal
Associate Editor
International Journal of Molecular Science
Journal of Clinical Medicine
Diagnostics
My Awards
Awards and Honors
1983-1989 Turkish Education Association Top student Turkey award for 6 consecutive years
1993 Japan Ministry of Health Monbusho Scholarship
1997 Kobe Mayor English Japanese Bilingual Speech Contest award
1997 Asahi newspaper Best Composition Award
1999 ARVO travel award
2000 Japan Cornea Congress Uchida Award for best cornea presentation
2002 Japan Society for Promotion of Science Postgraduate Scholarship
2007 Japan Dry Eye Society Research Award
+ Numerous TFOS ,ARVO and congress best presentation and travel awards for graduate and undergraduate students
My Research Activities
Murat's research interests include studying the pathophysiology of several types of dry eye disease and ocular allergy, discovering new diagnostic methods and biomarkers for dry eyes, the role of oxidative stress in ocular surface diseases, assessment of novel treatments for dry eyes and ocular allergies, studying animal models of ocular surface disease, role of aging on eyes, studying the effect of environmental factors on dry eyes and ocular allergy, the effect of contact lens wear on tear film and ocular surface, studying and devising CLs able to deliver therapeutic agents for ocular surface disease, meibomian gland disease.
My Research Supervision
Areas of supervision
Anterior segment, ocular surface disease, dry eyes, ocular allergy, contact lens, diagnostic imaging,
novel treatments for dry eyes, allergy and glaucoma
Currently supervising
Bioavailability of a novel antiglaucoma eye drop, its safety and ocular surface effects
My Teaching
I teach basic and advanced research and clinical skills to diagnose dry eyes, ocular allergies, glaucoma, uveitis, ocular effects of contact lens wear, histopathology of ocular tissues including immunohistochemistry,
Real Time RT-PCR and electron microscopy skills to undergraduate and postgraduate students.