By Professor David Thomas

Journal articles

Thomas D; Carriere P; Jacobs I, 2010, 'Safety of denosumab in giant-cell tumour of bone', Lancet Oncology, 11, pp. 815, http://dx.doi.org/10.1016/S1470-2045(10)70170-4

Thomas DM; Wagner AJ, 2010, 'Specific targets in sarcoma and developmental therapeutics', Jnccn Journal of the National Comprehensive Cancer Network, 8, pp. 677 - 685, http://dx.doi.org/10.6004/jnccn.2010.0050

Thomas DM, 2010, 'Wnts, bone and cancer', Journal of Pathology, 220, pp. 1 - 4, http://dx.doi.org/10.1002/path.2635

Thomas DM; Fox J; Haston CK, 2010, 'Imatinib therapy reduces radiation-induced pulmonary mast cell influx and delays lung disease in the mouse', International Journal of Radiation Biology, 86, pp. 436 - 444, http://dx.doi.org/10.3109/09553001003674863

Thomas D; Johnston V; Fitz J, 2010, 'Lessons for Aboriginal tobacco control in remote communities: an evaluation of the Northern Territory 'Tobacco Project'', AUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH, 34, pp. 45 - 49, http://dx.doi.org/10.1111/j.1753-6405.2010.00472.x

Conyers R; Thomas D, 2010, 'Review of “Cancer – basic science and clinical aspects”', BioEssays, 32, pp. 914 - 916, http://dx.doi.org/10.1002/bies.201000084

Angoa-Pérez M; Kreipke CW; Thomas DM; Van Shura KE; Lyman M; McDonough JH; Kuhn DM, 2010, 'Soman increases neuronal COX-2 levels: Possible link between seizures and protracted neuronal damage', NeuroToxicology, 31, pp. 738 - 746, http://dx.doi.org/10.1016/j.neuro.2010.06.007

Thomas DM, 2010, 'The importance of molecular and anatomic pathology in cancer management', Pathology, 42, pp. S31 - S31, http://dx.doi.org/10.1097/01268031-201042001-00063

Thomas DM, 2010, 'The importance of molecular and anatomic pathology in cancer management', Pathology, 42, pp. S12 - S12, http://dx.doi.org/10.1097/01268031-201042001-00014

Kong E; Gutierrez G; Thomas D; Hinds P, 2009, 'Abstract A10: Increased mesenchymal progenitor cells in RB1−/− bone', Cancer Research, 69, pp. A10 - A10, http://dx.doi.org/10.1158/0008-5472.fbcr09-a10

Garsed DW; Holloway AJ; Thomas DM, 2009, 'Cancer-associated neochromosomes: A novel mechanism of oncogenesis', Bioessays, 31, pp. 1191 - 1200, http://dx.doi.org/10.1002/bies.200800208

Fleming NI; Trivett MK; George J; Slavin JL; Murray WK; Moseley JM; Anderson RL; Thomas DM, 2009, 'Parathyroid hormone-related protein protects against mammary tumor emergence and is associated with monocyte infiltration in ductal carcinoma in situ (Cancer Research (2009) 69, (7473-7479))', Cancer Research, 69, pp. 8832, http://dx.doi.org/10.1158/0008-5472.CAN-09-3870

Fleming NI; Trivett MK; George J; Slavin JL; Murray WK; Moseley JM; Anderson RL; Thomas DM, 2009, 'Parathyroid hormone-related protein protects against mammary tumor emergence and is associated with monocyte infiltration in ductal carcinoma in situ', Cancer Research, 69, pp. 7473 - 7479, http://dx.doi.org/10.1158/0008-5472.CAN-09-0194

Thomas DM; O'Sullivan B; Gronchi A, 2009, 'Current concepts and future perspectives in retroperitoneal soft-tissue sarcoma management', Expert Review of Anticancer Therapy, 9, pp. 1145 - 1157, http://dx.doi.org/10.1586/ERA.09.77

Khamly KK; Thursfield VJ; Fay M; Desai J; Toner GC; Choong PFM; Ngan SYK; Powell GJ; Thomas DM, 2009, 'Gender-specific activity of chemotherapy correlates with outcomes in chemosensitive cancers of young adulthood', International Journal of Cancer, 125, pp. 426 - 431, http://dx.doi.org/10.1002/ijc.24376

Thomas DM; Skubitz KM, 2009, 'Giant cell tumour of bone', Current Opinion in Oncology, 21, pp. 338 - 344, http://dx.doi.org/10.1097/CCO.0b013e32832c951d

Soliman H; Ferrari A; Thomas D, 2009, 'Sarcoma in the Young Adult Population: An International View', Seminars in Oncology, 36, pp. 227 - 236, http://dx.doi.org/10.1053/j.seminoncol.2009.03.006

Thomas DM; Chawla S; Skubitz K; Staddon A; Henshaw R; Blay J; Smith J; Ye Z; Roudier M; Jun S, 2009, 'Denosumab for the treatment of giant cell tumor (GCT) of bone: Final results from a proof-of-concept, phase II study', Journal of Clinical Oncology, 27, pp. 10510 - 10510, http://dx.doi.org/10.1200/jco.2009.27.15_suppl.10510

Kansara M; Tsang M; Kodjabachian L; Sims NA; Trivett MK; Ehrich M; Dobrovic A; Slavin J; Choong PFM; Simmons PJ; Dawid IB; Thomas DM, 2009, 'Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice', Journal of Clinical Investigation, 119, pp. 837 - 851, http://dx.doi.org/10.1172/JCI37175

Thomas D; Whyte S; Choong P, 2009, 'Australian Sarcona Study Group: Development and outlook', Cancer Forum, 33, pp. 25 - 28

Pires de Camargo V; van de Rijn M; de Alava E; Madoz-Gúrpide J; Pilotti S; von Mehren M; Pedeutour F; Maki RG; Rutkowski P; Thomas DM, 2009, 'Other Targetable Sarcomas', Seminars in Oncology, 36, pp. 358 - 371, http://dx.doi.org/10.1053/j.seminoncol.2009.06.008

Thomas DM; Francescutti‐Verbeem DM; Kuhn DM, 2009, 'Increases in cytoplasmic dopamine compromise the normal resistance of the nucleus accumbens to methamphetamine neurotoxicity', Journal of Neurochemistry, 109, pp. 1745 - 1755, http://dx.doi.org/10.1111/j.1471-4159.2009.06094.x

Grant DG; Breitenfeldt N; Shepherd NA; Thomas DM, 2009, 'Intranodal neurilemmoma presenting as parotid mass', The Journal of Laryngology and Otology, 123, pp. 912 - 914, http://dx.doi.org/10.1017/s0022215108003496

Newnham GM; Thomas DM; McLachlan SA; Wright G; Conron M, 2008, 'Molecular Profiling of Non-Small Cell Lung Cancer: Of What Value in Clinical Practice?', Heart Lung and Circulation, 17, pp. 451 - 462, http://dx.doi.org/10.1016/j.hlc.2007.11.144

Gutierrez GM; Kong E; Sabbagh Y; Brown NE; Lee JS; Demay MB; Thomas DM; Hinds PW, 2008, 'Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice', Proceedings of the National Academy of Sciences of the United States of America, 105, pp. 18402 - 18407, http://dx.doi.org/10.1073/pnas.0805925105

Alvaro F; Young A; Goldstein D; Thomas D; McJannett M; Dillon R, 2008, 'Clinical oncological society of Australia: Adolescent and young adult cancer forum', Cancer Forum, 32, pp. 116 - 119

Thomas D; Chawla SP; Skubitz K; Staddon AP; Henshaw R; Blay JY; Smith J; Ye Z; Roudier M; Jun S, 2008, 'Denosumab treatment of giant cell tumor of bone: Interim analysis of an open-label phase II study', Journal of Clinical Oncology, 26, pp. 10500 - 10500, http://dx.doi.org/10.1200/jco.2008.26.15_suppl.10500

Bleyer A; Barr R; Hayes-Lattin B; Thomas D; Ellis C; Anderson B, 2008, 'The distinctive biology of cancer in adolescents and young adults', Nature Reviews Cancer, 8, pp. 288 - 298, http://dx.doi.org/10.1038/nrc2349

Khamly KK; Hicks RJ; McArthur GA; Thomas DM, 2008, 'The promise of PET in clinical management and as a sensitive test for drug cytotoxicity in sarcomas', Expert Review of Molecular Diagnostics, 8, pp. 105 - 119, http://dx.doi.org/10.1586/14737159.8.1.105

Thomas DM; Francescutti‐Verbeem DM; Kuhn DM, 2008, 'Methamphetamine‐induced neurotoxicity and microglial activation are not mediated by fractalkine receptor signaling', Journal of Neurochemistry, 106, pp. 696 - 705, http://dx.doi.org/10.1111/j.1471-4159.2008.05421.x

Clark JCM; Thomas DM; Choong PFM; Dass CR, 2007, 'RECK - A newly discovered inhibitor of metastasis with prognostic significance in multiple forms of cancer', Cancer and Metastasis Reviews, 26, pp. 675 - 683, http://dx.doi.org/10.1007/s10555-007-9093-8

Fon A; Mileshkin L; Slavin J; Twomey H; James P; Thomas DM, 2007, 'Synchronous diagnosis of Hodgkin lymphoma and osteosarcoma [1]', Internal Medicine Journal, 37, pp. 731 - 732, http://dx.doi.org/10.1111/j.1445-5994.2007.01465.x

Thomas DM, 2007, 'Adolescents and young adults with cancer: The challenge', Palliative and Supportive Care, 5, pp. 173 - 174, http://dx.doi.org/10.1017/S1478951507070253

Kansara M; Thomas DM, 2007, 'Molecular pathogenesis of osteosarcoma', DNA and Cell Biology, 26, pp. 1 - 18, http://dx.doi.org/10.1089/dna.2006.0505

Thomas D, 2007, 'Not part of the public: Non-indigenous policies and practices and the health of Indigenous South Australians 1836-1973', AUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH, 31, pp. 193 - 194, http://dx.doi.org/10.1111/j.1753-6405.2007.00044.x

Esler DM; Johnston F; Thomas D, 2007, 'The acceptability of a depression screening tool in an urban, Aboriginal community‐controlled health service', Australian and New Zealand Journal of Public Health, 31, pp. 259 - 263, http://dx.doi.org/10.1111/j.1467-842x.2007.00058.x

Krypuy M; Newnham GM; Thomas DM; Conron M; Dobrovic A, 2006, 'High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer', BMC Cancer, 6, http://dx.doi.org/10.1186/1471-2407-6-295

Chaffer CL; Thomas DM; Thompson EW; Williams ED, 2006, 'PPARγ-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma', BMC Cancer, 6, http://dx.doi.org/10.1186/1471-2407-6-53

Tan JZY; Schlicht SM; Powell GJ; Thomas D; Slavin JL; Smith PJ; Choong PFM, 2006, 'Multidisciplinary approach to diagnosis and management of osteosarcoma - A review of the St Vincent's Hospital experience', International Seminars in Surgical Oncology, 3, http://dx.doi.org/10.1186/1477-7800-3-38

Thomas D; Kansara M, 2006, 'Epigenetic modifications in osteogenic differentiation and transformation', Journal of Cellular Biochemistry, 98, pp. 757 - 769, http://dx.doi.org/10.1002/jcb.20850

Vamre TBA; Stalsberg H; Thomas DB; Berry G; Maclennan R; Shearman R; Jelihovsky T; Booth JC; Molina R; Martinez L; Salas O; Dabacens A; Zhiheng C; Yun T; Wei HY; Cuadros A; Aristizabal N; Ebeling K; Nishan P; Kunde D; Modan B; Ron E; Alfandary E; Mati JG; Kenya P; Kungu A; Gatei D; Cuevas HR; Salazar SB; Palet A; Ontiveros P; Apelo RA; De La Cruz JR; Baens J; Javier B; Silpisornkosol S; Pardthaisong T; Martin N; Theetranont C; Boosiri B; Chutivongse S; Virutamasen P; Wongsrichanalai C; Jimakorn P; Koetsawang S; Rachawat D; Chantarakul N; Ray RM; Noonan EA; Holck S, 2006, 'Extra-tumoral breast tissue in breast cancer patients: Variations with steroid contraceptive use', International Journal of Cancer, 118, pp. 2827 - 2831, http://dx.doi.org/10.1002/ijc.21697

Lee JS; Thomas DM; Gutierrez G; Carty SA; Yanagawa SI; Hinds PW, 2006, 'HES1 cooperates with pRb to activate RUNX2-dependent transcription', Journal of Bone and Mineral Research, 21, pp. 921 - 933, http://dx.doi.org/10.1359/jbmr.060303

Thomas DM; Seymour JF; O'Brien T; Sawyer SM; Ashley DM, 2006, 'Adolescent and young adult cancer: A revolution in evolution?', Internal Medicine Journal, 36, pp. 302 - 307, http://dx.doi.org/10.1111/j.1445-5994.2006.01062.x

Amukotuwa SA; Choong PFM; Smith PJ; Powell GJ; Thomas D; Schlicht SM, 2006, 'Femoral mesenchymal chondrosarcoma with secondary aneurysmal bone cysts mimicking a small-cell osteosarcoma', Skeletal Radiology, 35, pp. 311 - 318, http://dx.doi.org/10.1007/s00256-005-0044-6

Slavin JL; Thomas D, 2006, 'Gene expression profiling of sarcomas', Pathology, 38, pp. 101 - 102, http://dx.doi.org/10.1080/00313020600595854

Gold LS; De Roos AJ; Ray RM; Wernli K; Fitzgibbons ED; Gao D-L; Astrakianakis G; Feng Z; Thomas D; Checkoway H, 2006, 'Brain tumors and occupational exposures in a cohort of female textile workers in Shanghai, China.', Scandinavian Journal of Work, Environment & Health, 32, pp. 178 - 184, http://dx.doi.org/10.5271/sjweh.996

Cullinane C; Dorow DS; Kansara M; Conus N; Binns D; Hicks RJ; Ashman LK; McArthur GA; Thomas DM, 2005, 'An in vivo tumor model exploiting metabolic response as a biomarker for targeted drug development', Cancer Research, 65, pp. 9633 - 9636, http://dx.doi.org/10.1158/0008-5472.CAN-05-2285

Dudley AC; Thomas D; Best J; Jenkins A, 2005, 'A VEGF/JAK2/STAT5 axis may partially mediate endothelial cell tolerance to hypoxia', Biochemical Journal, 390, pp. 427 - 436, http://dx.doi.org/10.1042/BJ20050351

Morgan T; Atkins GJ; Trivett MK; Johnson SA; Kansara M; Schlicht SL; Slavin JL; Simmons P; Dickinson I; Powell G; Choong PFM; Holloway AJ; Thomas DM, 2005, 'Molecular profiling of giant cell tumor of bone and the osteoclastic localization of ligand for receptor activator of nuclear factor κB', American Journal of Pathology, 167, pp. 117 - 128, http://dx.doi.org/10.1016/S0002-9440(10)62959-8

Thomas DM; Johnson SA; Sims NA; Trivett MK; Slavin JL; Rubin BP; Waring P; McArthur GA; Walkley CR; Holloway AJ; Diyagama D; Grim JE; Clurman BE; Bowtell DDL; Lee JS; Gutierrez GM; Piscopo DM; Carty SA; Hinds PW, 2004, 'Terminal osteoblast differentiation, mediated by runx2 and p27 KIP1, is disrupted in osteosarcoma', Journal of Cell Biology, 167, pp. 925 - 934, http://dx.doi.org/10.1083/jcb.200409187

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