By Professor Kate Louise Seib

Journal articles

Serruto D; Spadafina T; Ciucchi L; Lewis LA; Ram S; Tontini M; Santini L; Biolchi A; Seib KL; Giuliani MM; Donnelly JJ; Berti F; Savino S; Scarselli M; Costantino P; Simon Kroll J; O'Dwyer C; Qiu J; Plaut AG; Moxon R; Rappuoli R; Pizza M; Aricò B, 2010, 'Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans', Proceedings of the National Academy of Sciences of the United States of America, 107, pp. 3770 - 3775, http://dx.doi.org/10.1073/pnas.0915162107

Seib KL; Dougan G; Rappuoli R, 2009, 'The key role of genomics in modern vaccine and drug design for emerging infectious diseases', Plos Genetics, 5, http://dx.doi.org/10.1371/journal.pgen.1000612

Rinaudo CD; Telford JL; Rappuoli R; Seib KL, 2009, 'Vaccinology in the genome era', Journal of Clinical Investigation, 119, pp. 2515 - 2525, http://dx.doi.org/10.1172/JCI38330

Fantappiè L; Metruccio MME; Seib KL; Oriente F; Cartocci E; Ferlicca F; Giuliani MM; Scarlato V; Delany I, 2009, 'The RNA chaperone Hfq is involved in stress response and virulence in Neisseria meningitidis and is a pleiotropic regulator of protein expression', Infection and Immunity, 77, pp. 1842 - 1853, http://dx.doi.org/10.1128/IAI.01216-08

Srikhanta YN; Dowideit SJ; Edwards JL; Falsetta ML; Wu HJ; Harrison OB; Fox KL; Seib KL; Maguire TL; Wang AHJ; Maiden MC; Grimmond SM; Apicella MA; Jennings MP, 2009, 'Phasevarions mediate random switching of gene expression in pathogenic Neisseria', Plos Pathogens, 5, http://dx.doi.org/10.1371/journal.ppat.1000400

Seib KL; Serruto D; Oriente F; Delany I; Adu-Bobie J; Veggi D; Aricò B; Rappuoli R; Pizza M, 2009, 'Factor H-binding protein is important for meningococcal survival in human whole blood and serum and in the presence of the antimicrobial peptide LL-37', Infection and Immunity, 77, pp. 292 - 299, http://dx.doi.org/10.1128/IAI.01071-08

Ieva R; Roncarati D; Metruccio MME; Seib KL; Scarlato V; Delany I, 2008, 'OxyR tightly regulates catalase expression in Neisseria meningitidis through both repression and activation mechanisms', Molecular Microbiology, 70, pp. 1152 - 1165, http://dx.doi.org/10.1111/j.1365-2958.2008.06468.x

Seib KL; Wu HJ; Srikhanta YN; Edwards JL; Falsetta ML; Hamilton AJ; Maguire TL; Grimmond SM; Apicella MA; McEwan AG; Jennings MP, 2007, 'Characterization of the OxyR regulon of Neisseria gonorrhoeae', Molecular Microbiology, 63, pp. 54 - 68, http://dx.doi.org/10.1111/j.1365-2958.2006.05478.x

Power PM; Seib KL; Jennings MP, 2006, 'Pilin glycosylation in Neisseria meningitidis occurs by a similar pathway to wzy-dependent O-antigen biosynthesis in Escherichia coli', Biochemical and Biophysical Research Communications, 347, pp. 904 - 908, http://dx.doi.org/10.1016/j.bbrc.2006.06.182

Seib KL; Wu HJ; Kidd SP; Apicella MA; Jennings MP; McEwan AG, 2006, 'Defenses against oxidative stress in Neisseria gonorrhoeae: A system tailored for a challenging environment', Microbiology and Molecular Biology Reviews, 70, pp. 344 - 361, http://dx.doi.org/10.1128/MMBR.00044-05

Wu HJ; Seib KL; Srikhanta YN; Kidd SP; Edwards JL; Maguire TL; Grimmond SM; Apicella MA; McEwan AG; Jennings MP, 2006, 'PerR controls Mn-dependent resistance to oxidative stress in Neisseria gonorrhoeae', Molecular Microbiology, 60, pp. 401 - 416, http://dx.doi.org/10.1111/j.1365-2958.2006.05079.x

Wu HJ; Seib KL; Edwards JL; Apicella MA; McEwan AG; Jennings MP, 2005, 'Azurin of pathogenic Neisseria spp. is involved in defense against hydrogen peroxide and survival within cervical epithelial cells', Infection and Immunity, 73, pp. 8444 - 8448, http://dx.doi.org/10.1128/IAI.73.12.8444-8448.2005

Seib KL; Simons MP; Wu HJ; McEwan AG; Nauseef WM; Apicella MA; Jennings MP, 2005, 'Investigation of oxidative stress defenses of Neisseria gonorrhoeae by using a human polymorphonuclear leukocyte survival assay', Infection and Immunity, 73, pp. 5269 - 5272, http://dx.doi.org/10.1128/IAI.73.8.5269-5272.2005

Seib KL; Tseng HJ; McEwan AG; Apicella MA; Jennings MP, 2004, 'Defenses against oxidative stress in Neisseria gonorrhoeae and Neisseria meningitidis: Distinctive systems for different lifestyles', Journal of Infectious Diseases, 190, pp. 136 - 147, http://dx.doi.org/10.1086/421299

Seib KL; Jennings MP; McEwan AG, 2003, 'A Sco homologue plays a role in defence against oxidative stress in pathogenic Neisseria', FEBS Letters, 546, pp. 411 - 415, http://dx.doi.org/10.1016/S0014-5793(03)00632-X

Seib KL; Peak IRA; Jennings MP, 2002, 'Phase variable restriction-modification systems in Moraxella catarrhalis', FEMS Immunology and Medical Microbiology, 34, pp. 159 - 165, http://dx.doi.org/10.1111/j.1574-695X.2002.tb00548.x

Seib K, 2002, 'Phase variable restriction–modification systems in Moraxella catarrhalis', Pathogens and Disease, 32, pp. 159 - 165, http://dx.doi.org/10.1016/s0928-8244(01)00294-2

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