By Professor Kerry-Anne Rye

Journal articles

Barter PJ; Tabet F; Rye KA, 2015, 'Reduction in PCSK9 levels induced by anacetrapib: an off-target effect?', Journal of lipid research, 56, pp. 2045 - 2047, http://dx.doi.org/10.1194/jlr.C063768

Wu BJ; Shrestha S; Ong KL; Johns D; Dunn LL; Hou L; Barter PJ; Rye KA, 2015, 'Increasing HDL levels by inhibiting cholesteryl ester transfer protein activity in rabbits with hindlimb ischemia is associated with increased angiogenesis', International Journal of Cardiology, 199, pp. 204 - 212, http://dx.doi.org/10.1016/j.ijcard.2015.07.014

Ong KL; Januszewski AS; O’Connell R; Buizen L; Jenkins AJ; Xu A; Sullivan DR; Barter PJ; Scott RS; Taskinen MR; Rye KA; Keech AC, 2015, 'Relationship of fibroblast growth factor 21 with baseline and new on-study microvascular disease in the Fenofibrate Intervention and Event Lowering in Diabetes study', Diabetologia, 58, pp. 2035 - 2044, http://dx.doi.org/10.1007/s00125-015-3652-2

Barter PJ; Nicholls SJ; Kastelein JJP; Rye KA, 2015, 'Is cholesteryl ester transfer protein inhibition an effective strategy to reduce cardiovascular risk?: CETP inhibition as a strategy to reduce cardiovascular risk: The pro case', Circulation, 132, pp. 423 - 432, http://dx.doi.org/10.1161/CIRCULATIONAHA.114.014025

Ong KL; Ding J; McClelland RL; Cheung BMY; Criqui MH; Barter PJ; Rye KA; Allison MA, 2015, 'Relationship of pericardial fat with lipoprotein distribution: The Multi-Ethnic study of atherosclerosis', Atherosclerosis, 241, pp. 664 - 670, http://dx.doi.org/10.1016/j.atherosclerosis.2015.06.027

Rye KA; Ong KL, 2015, 'HDL function as a predictor of coronary heart disease events: Time to re-assess the HDL hypothesis?', The Lancet Diabetes and Endocrinology, 3, pp. 488 - 489, http://dx.doi.org/10.1016/S2213-8587(15)00205-3

Ong KL; Ding J; McClelland RL; Cheung BMY; Criqui MH; Barter PJ; Rye KA; Allison MA, 2015, 'Relationship of pericardial fat with biomarkers of inflammation and hemostasis, and cardiovascular disease: The Multi-Ethnic Study of Atherosclerosis', Atherosclerosis, 239, pp. 386 - 392, http://dx.doi.org/10.1016/j.atherosclerosis.2015.01.033

Du XM; Kim MJ; Hou L; Le Goff W; Chapman MJ; Van Eck M; Curtiss LK; Burnett JR; Cartland SP; Quinn CM; Kockx M; Kontush A; Rye KA; Kritharides L; Jessup W, 2015, 'HDL particle size is a critical determinant of ABCA1-mediated macrophage cellular cholesterol export', Circulation Research, 116, pp. 1133 - 1142, http://dx.doi.org/10.1161/CIRCRESAHA.116.305485

Wu BJ; Shrestha S; Ong KL; Johns D; Hou L; Barter PJ; Rye KA, 2015, 'Cholesteryl Ester Transfer Protein Inhibition Enhances Endothelial Repair and Improves Endothelial Function in the Rabbit', Arteriosclerosis, Thrombosis, and Vascular Biology, 35, pp. 628 - 636, http://dx.doi.org/10.1161/ATVBAHA.114.304747

Ong KL; Januszewski AS; O’Connell R; Jenkins AJ; Xu A; Sullivan DR; Barter PJ; Hung WT; Scott RS; Taskinen MR; Keech AC; Rye KA, 2015, 'The relationship of fibroblast growth factor 21 with cardiovascular outcome events in the Fenofibrate Intervention and Event Lowering in Diabetes study', Diabetologia, 58, pp. 464 - 473, http://dx.doi.org/10.1007/s00125-014-3458-7

Zhang M; Charles R; Tong H; Zhang L; Patel M; Wang F; Rames MJ; Ren A; Rye KA; Qiu X; Johns DG; Charles MA; Ren G, 2015, 'HDL surface lipids mediate CETP binding as revealed by electron microscopy and molecular dynamics simulation', Scientific Reports, 5, http://dx.doi.org/10.1038/srep08741

Besseling J; Ong KL; Huijgen R; Rye KA; Hovingh GK; Hutten BA; Lambert G, 2015, 'The impact of LDLR function on fibroblast growth factor 21 levels', Atherosclerosis, 241, pp. 322 - 325, http://dx.doi.org/10.1016/j.atherosclerosis.2015.05.032

Di Bartolo BA; Cartland SP; Vellozzi M; Rye K-A; Kavurma MM, 2015, 'Abstract 103: HDL Improves Cholesterol and Glucose Homeostasis and Reduces Atherosclerosis in TRAIL-/-ApoE-/- mice', Arteriosclerosis, Thrombosis, and Vascular Biology, 35, http://dx.doi.org/10.1161/atvb.35.suppl_1.103

Tabet F; Cuesta Torres LF; Wiese CB; Öhrling G; Larsson R; Barter PJ; Vickers KC; Rye K-A, 2015, 'Abstract 47: High-Density Lipoproteins Induce Neutrophil-miRNA Transcription and Export: Contribution to HDL-miRNA Cell to Cell Communication', Arteriosclerosis, Thrombosis, and Vascular Biology, 35, http://dx.doi.org/10.1161/atvb.35.suppl_1.47

Lambert G; Chatelais M; Petrides F; Passard M; Thedrez A; Rye KA; Schwahn U; Gusarova V; Blom DJ; Sasiela W; Marais AD, 2014, 'Normalization of low-density lipoprotein receptor expression in receptor defective homozygous familial hypercholesterolemia by inhibition of PCSK9 with alirocumab', Journal of the American College of Cardiology, 64, pp. 2299 - 2300, http://dx.doi.org/10.1016/j.jacc.2014.07.995

Vickers KC; Landstreet SR; Levin MG; Shoucri BM; Toth CL; Taylor RC; Palmisano BT; Tabet F; Cui HL; Rye KA; Sethupathy P; Remaley AT, 2014, 'MicroRNA-223 coordinates cholesterol homeostasis', Proceedings of the National Academy of Sciences of the United States of America, 111, pp. 14518 - 14523, http://dx.doi.org/10.1073/pnas.1215767111

Ong KL; McClelland RL; Rye KA; Cheung BMY; Post WS; Vaidya D; Criqui MH; Cushman M; Barter PJ; Allison MA, 2014, 'The relationship between insulin resistance and vascular calcification in coronary arteries, and the thoracic and abdominal aorta: The multi-ethnic study of atherosclerosis', Atherosclerosis, 236, pp. 257 - 262, http://dx.doi.org/10.1016/j.atherosclerosis.2014.07.015

Cochran BJ; Bisoendial RJ; Hou L; Glaros E; Rossy J; Thomas SR; Barter PJ; Rye KA, 2014, 'Apolipoprotein a-I increases insulin secretion and production from pancreatic β-cells via a g-protein-camp-PKA-FOXO1-dependent mechanism', Arteriosclerosis, Thrombosis, and Vascular Biology, http://dx.doi.org/10.1161/ATVBAHA.114.304131

Lambert G; Petrides F; Chatelais M; Blom DJ; Choque B; Tabet F; Wong G; Rye KA; Hooper AJ; Burnett JR; Barter PJ; Marais AD, 2014, 'Elevated plasma PCSK9 level is equally detrimental for patients with nonfamilial hypercholesterolemia and heterozygous familial hypercholesterolemia, irrespective of low-density lipoprotein receptor defects', Journal of the American College of Cardiology, 63, pp. 2365 - 2373, http://dx.doi.org/10.1016/j.jacc.2014.02.538

Ong KL; Waters DD; Messig M; Demicco DA; Rye KA; Barter PJ, 2014, 'Effect of change in body weight on incident diabetes mellitus in patients with stable coronary artery disease treated with atorvastatin (from the Treating to New Targets Study)', American Journal of Cardiology, 113, pp. 1593 - 1598, http://dx.doi.org/10.1016/j.amjcard.2014.02.011

Ong KL; Allison MA; Cheung BMY; Wu BJ; Barter PJ; Rye KA; Wu B, 2014, 'The relationship between total Bilirubin levels and total mortality in older adults: The United States national health and nutrition examination survey (NHANES) 1999-2004', PLoS ONE, 9, pp. e94479, http://dx.doi.org/10.1371/journal.pone.0094479

Rye KA, 2014, 'Biomarkers associated with high-density lipoproteins in atherosclerotic kidney disease', Clinical and Experimental Nephrology, 18, pp. 247 - 250, http://dx.doi.org/10.1007/s10157-013-0865-x

Charlton F; Tooher J; Rye KA; Hennessy A, 2014, 'Cardiovascular risk, lipids and pregnancy: Preeclampsia and the risk of later life cardiovascular disease', Heart Lung and Circulation, 23, pp. 203 - 212, http://dx.doi.org/10.1016/j.hlc.2013.10.087

Wu BJ; Ong KL; Shrestha S; Chen K; Tabet F; Barter PJ; Rye KA, 2014, 'Inhibition of arthritis in the lewis rat by apolipoprotein A-I and reconstituted high-density lipoproteins', Arteriosclerosis, Thrombosis, and Vascular Biology, 34, pp. 543 - 551, http://dx.doi.org/10.1161/ATVBAHA.113.302832

Tabet F; Vickers KC; Cuesta Torres LF; Wiese CB; Shoucri BM; Lambert G; Catherinet C; Prado-Lourenco L; Levin MG; Thacker S; Sethupathy P; Barter PJ; Remaley AT; Rye KA, 2014, 'HDL-transferred microRNA-223 regulates ICAM-1 expression in endothelial cells', Nature Communications, 5, http://dx.doi.org/10.1038/ncomms4292

Rye KA; Barter PJ, 2014, 'Thematic review series: High density lipoprotein structure, function, and metabolism cardioprotective functions of HDLs 1', Journal of Lipid Research, 55, pp. 168 - 179, http://dx.doi.org/10.1194/jlr.R039297

Rye KA; Barter PJ, 2014, 'Regulation of high-density lipoprotein metabolism', Circulation Research, 114, pp. 143 - 156, http://dx.doi.org/10.1161/CIRCRESAHA.114.300632

McGrath KC; Li XH; Whitworth PT; Kasz R; Tan JT; McLennan SV; Celermajer DS; Barter PJ; Rye KA; Heather AK, 2014, 'High density lipoproteins improve insulin sensitivity in high-fat diet-fed mice by suppressing hepatic inflammation', Journal of Lipid Research, 55, pp. 421 - 430, http://dx.doi.org/10.1194/jlr.M043281

Vickers KC; Rye KA; Tabet F, 2014, 'MicroRNAs in the onset and development of cardiovascular disease', Clinical Science, 126, pp. 183 - 194, http://dx.doi.org/10.1042/CS20130203

Wiese CB; Toth CL; Tabet F; Taylor RC; Landstreet SR; Rye K-A; Hofmeister LH; Harrison DG; Kon V; Vickers KC, 2014, 'Abstract 3: HDL-MicroRNA-92a and Interleukin-33 Axis Underlies Endothelial Dysfunction Associated With Atherosclerosis and Chronic Kidney Disease', Arteriosclerosis, Thrombosis, and Vascular Biology, 34, http://dx.doi.org/10.1161/atvb.34.suppl_1.3

Tabet F; Lee S; Cuesta Torres LF; Levin MG; Drummond GR; Remaley AT; Rye K-A; Sobey CG; Vickers KC, 2014, 'Abstract 312: Transcriptional and Posttranscriptional Circuitry in the Brain After Transient and Permanent Ischemia', Arteriosclerosis, Thrombosis, and Vascular Biology, 34, http://dx.doi.org/10.1161/atvb.34.suppl_1.312

Tabet F; Vickers KC; Cuesta Torres LF; Ammori B; Yadav R; Hama S; Liu Y; Schofield J; Barter P; Soran H; Rye K-A, 2014, 'Abstract 612: Effect of Bariatric Surgery on HDL-Associated MicroRNAs', Arteriosclerosis, Thrombosis, and Vascular Biology, 34, http://dx.doi.org/10.1161/atvb.34.suppl_1.612

Rye KA, 2013, 'High density lipoprotein structure, function, and metabolism: A new Thematic Series', Journal of Lipid Research, 54, pp. 2031 - 2033, http://dx.doi.org/10.1194/jlr.E041350

Ong KL; Allison MA; Cheung BMY; Wu BJ; Barter PJ; Rye KA; Wu B, 2013, 'Trends in C-reactive protein levels in US adults from 1999 to 2010', American Journal of Epidemiology, 177, pp. 1430 - 1442, http://dx.doi.org/10.1093/aje/kws443

Brown BE; Nobecourt E; Zeng J; Jenkins AJ; Rye KA; Davies MJ, 2013, 'Apolipoprotein A-I glycation by Glucose and Reactive Aldehydes Alters Phospholipid Affinity but Not Cholesterol Export from Lipid-Laden Macrophages', PLoS ONE, 8, http://dx.doi.org/10.1371/journal.pone.0065430

Yu S; Youssef P; Tabet F; Rye K; Bisoendial R, 2013, 'HIGH DENSITY LIPOPROTEIN FUNCTION IN RHEUMATOID ARTHRITIS BEFORE AND AFTER TNF alpha INHIBITION', INTERNAL MEDICINE JOURNAL, 43, pp. 9 - 9, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000318185100029&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Mulay V; Wood P; Manetsch M; Darabi M; Cairns R; Hoque M; Chan KC; Reverter M; Álvarez-Guaita A; Rye KA; Rentero C; Heeren J; Enrich C; Grewal T, 2013, 'Inhibition of Mitogen-Activated Protein Kinase Erk1/2 Promotes Protein Degradation of ATP Binding Cassette Transporters A1 and G1 in CHO and HuH7 Cells', PLoS ONE, 8, http://dx.doi.org/10.1371/journal.pone.0062667

Huijgen R; Boekholdt SM; Arsenault BJ; Bao W; Davaine JM; Tabet F; Petrides F; Rye KA; DeMicco DA; Barter PJ; Kastelein JJP; Lambert G, 2013, 'Erratum: Plasma PCSK9 levels and clinical outcomes in the TNT (Treating to New Targets) Trial (Journal of the American College of Cardiology (2012) 59 (1778-1784))', Journal of the American College of Cardiology, 61, pp. 1751, http://dx.doi.org/10.1016/j.jacc.2013.04.002

Van Der Vorst EPC; Vanags LZ; Dunn LL; Prosser HC; Rye KA; Bursill CA, 2013, 'High-density lipoproteins suppress chemokine expression and proliferation in human vascular smooth muscle cells', FASEB Journal, 27, pp. 1413 - 1425, http://dx.doi.org/10.1096/fj.12-212753

Chung RWS; Kamili A; Tandy S; Weir JM; Gaire R; Wong G; Meikle PJ; Cohn JS; Rye KA, 2013, 'Dietary Sphingomyelin Lowers Hepatic Lipid Levels and Inhibits Intestinal Cholesterol Absorption in High-Fat-Fed Mice', PLoS ONE, 8, http://dx.doi.org/10.1371/journal.pone.0055949

Wu BJ; Chen K; Shrestha S; Ong KL; Barter PJ; Rye KA, 2013, 'High-density lipoproteins inhibit vascular endothelial inflammation by increasing 3β-hydroxysteroid-[INCREMENT]24 reductase expression and inducing heme oxygenase-1', Circulation Research, 112, pp. 278 - 288, http://dx.doi.org/10.1161/CIRCRESAHA.111.300104

Hadfield KA; Pattison DI; Brown BE; Hou L; Rye KA; Davies MJ; Hawkins CL, 2013, 'Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins: Comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl)', Biochemical Journal, 449, pp. 531 - 542, http://dx.doi.org/10.1042/BJ20121210

Ong KL; Wu BJ; Cheung BMY; Barter PJ; Rye KA; Wu B, 2013, 'Arthritis: Its prevalence, Risk factors, And association with cardiovascular diseases in the United States, 1999 to 2008', Annals of Epidemiology, 23, pp. 80 - 86, http://dx.doi.org/10.1016/j.annepidem.2012.11.008

Wu BJ; Ong KL; Shrestha S; Chen K; Barter PJ; Rye K-A, 2013, 'Abstract 3: Apolipoprotein A-I Inhibits Streptococcal Cell Wall-Induced Arthritis in the Rat in an ABCA1-dependent Manner', Arteriosclerosis, Thrombosis, and Vascular Biology, 33, http://dx.doi.org/10.1161/atvb.33.suppl_1.a3

Tso C; Rye K; Barter P, 2013, 'Effects of Low-Density Lipoproteins on Endothelium-Generation from Human Peripheral Blood Mononuclear Cells', Heart, Lung and Circulation, 22, pp. S16 - S16, http://dx.doi.org/10.1016/j.hlc.2013.05.034

Bisoendial R; Roediger B; Jain R; Cavanagh L; Tak P-P; Rye K-A; Weninger W, 2013, 'THU0096 Targeting Lymphatic Dysfunction in Rheumatoid Arthritis by High-Density Lipoprotein', Annals of the Rheumatic Diseases, 72, pp. A195.2 - A195, http://dx.doi.org/10.1136/annrheumdis-2013-eular.624

Ong KL; Rye KA; O'Connell R; Jenkins AJ; Brown C; Xu A; Sullivan DR; Barter PJ; Keech AC, 2012, 'Long-term fenofibrate therapy increases fibroblast growth factor 21 and retinol-binding protein 4 in subjects with type 2 diabetes', Journal of Clinical Endocrinology and Metabolism, 97, pp. 4701 - 4708, http://dx.doi.org/10.1210/jc.2012-2267

Barter PJ; Rye KA; Beltangady MS; Ports WC; Duggan WT; Boekholdt SM; DeMicco DA; Kastelein JJP; Shear CL, 2012, 'Relationship between atorvastatin dose and the harm caused by torcetrapib', Journal of Lipid Research, 53, pp. 2436 - 2442, http://dx.doi.org/10.1194/jlr.P026328

Barter PJ; Rye KA, 2012, 'Cholesteryl ester transfer protein inhibition as a strategy to reduce cardiovascular risk', Journal of Lipid Research, 53, pp. 1755 - 1766, http://dx.doi.org/10.1194/jlr.R024075

Ismael F; Hadfield KA; Pattison DI; Rye KA; Davies MJ; Hawkins CL, 2012, 'Role of lipoprotein modification by the myeloperoxidase-derived oxidant HOSCN in the formation of foam cells in atherosclerosis', FREE RADICAL BIOLOGY AND MEDICINE, 53, pp. S130 - S131, http://dx.doi.org/10.1016/j.freeradbiomed.2012.08.273

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