Select Publications
Journal articles
2013, 'HIV replication alters the composition of extrinsic pathway coagulation factors and increases thrombin generation.', Journal of the American Heart Association, 2, http://dx.doi.org/10.1161/JAHA.113.000264
,2013, 'Protease inhibitors and cardiac autonomic function in HIV-infected patients: a cross-sectional analysis from the Strategies for Management of Antiretroviral Therapy (SMART) Trial', BMJ OPEN, 3, http://dx.doi.org/10.1136/bmjopen-2012-002523
,2013, 'Results of external quality assessment for proviral DNA testing of HIV tropism in the Maraviroc switch collaborative study', Journal of Clinical Microbiology, 51, pp. 2063 - 2071, http://dx.doi.org/10.1128/JCM.00510-13
,2013, 'Biomarkers and Bacterial Pneumonia Risk in Patients with Treated HIV Infection: A Case-Control Study', PLoS ONE, 8, pp. e56249, http://dx.doi.org/10.1371/journal.pone.0056249
,2013, 'Mortality in well controlled HIV in the continuous antiretroviral therapy arms of the SMART and ESPRIT trials compared with the general population', AIDS, 27, pp. 973 - 979, http://dx.doi.org/10.1097/QAD.0b013e32835cae9c
,2013, 'Ritonavir-boosted lopinavir plus nucleoside or nucleotide reverse transcriptase inhibitors versus ritonavir-boosted lopinavir plus raltegravir for treatment of HIV-1 infection in adults with virological failure of a standard first-line ART regimen (SECOND-LINE): A randomised, open-label, non-inferiority study', Lancet, 381, pp. 2091 - 2099, http://dx.doi.org/10.1016/S0140-6736(13)61164-2
,2013, 'The Association between Serum Biomarkers and Disease Outcome in Influenza A(H1N1)pdm09 Virus Infection: Results of Two International Observational Cohort Studies', PLoS ONE, 8, pp. e57121, http://dx.doi.org/10.1371/journal.pone.0057121
,2013, 'The Potential Cost and Benefits of Raltegravir in Simplified Second-Line Therapy among HIV Infected Patients in Nigeria and South Africa', PLoS ONE, 8, pp. e54435, http://dx.doi.org/10.1371/journal.pone.0054435
,2012, 'Inflammation, coagulation and cardiovascular disease in HIV-infected individuals', PLoS ONE, 7, http://dx.doi.org/10.1371/journal.pone.0044454
,2012, 'Extended follow-up confirms early vaccine-enhanced risk of HIV acquisition and demonstrates waning effect over time among participants in a randomized trial of recombinant adenovirus HIV vaccine (Step Study)', Journal of Infectious Diseases, 206, pp. 258 - 266, http://dx.doi.org/10.1093/infdis/jis342
,2012, 'Optimising the manufacture, formulation, and dose of antiretroviral drugs for more cost-efficient delivery in resource-limited settings: A consensus statement', The Lancet Infectious Diseases, 12, pp. 550 - 560, http://dx.doi.org/10.1016/S1473-3099(12)70134-2
,2012, 'HIV replication, inflammation, and the effect of starting antiretroviral therapy on plasma asymmetric dimethylarginine, a novel marker of endothelial dysfunction', Journal of Acquired Immune Deficiency Syndromes, 60, pp. 128 - 134, http://dx.doi.org/10.1097/QAI.0b013e318252f99f
,2012, 'Pre-ART Levels of Inflammation and Coagulation Markers Are Strong Predictors of Death in a South African Cohort with Advanced HIV Disease', PLOS ONE, 7, http://dx.doi.org/10.1371/journal.pone.0024243
,2012, 'A randomized study of pharmacokinetics, efficacy, and safety of 2 raltegravir plus atazanavir strategies in ART-treated adults', JAIDS: Journal of Acquired Immune Deficiency Syndromes, 60, pp. 143 - 149, http://dx.doi.org/10.1097/QAI.0b013e318252f97e
,2012, 'Changes in Bone Turnover and Bone Loss in HIV-Infected Patients Changing Treatment to Tenofovir-Emtricitabine or Abacavir-Lamivudine', PLoS ONE, 7, pp. e38377, http://dx.doi.org/10.1371/journal.pone.0038377
,2012, 'Considerations in the rationale, design and methods of the Strategic Timing of AntiRetroviral Treatment (START) study', CLINICAL TRIALS, pp. 1 - 32, http://dx.doi.org/10.1177/1740774512440342
,2012, 'Dynamics of cognitive change in HIV-infected individuals commencing three different initial antiretroviral regimens: A randomized, controlled study', HIV Medicine, 13, pp. 245 - 251, http://dx.doi.org/10.1111/j.1468-1293.2011.00962.x
,2012, 'Integrated HIV DNA accumulates prior to treatment while episomal HIV DNA records ongoing transmission afterwards', AIDS, 26, pp. 543 - 550, http://dx.doi.org/10.1097/QAD.0b013e328350fb3c
,2012, 'Pharmacokinetics of lamivudine and lamivudine-triphosphate after administration of 300 milligrams and 150 milligrams once daily to healthy volunteers: Results of the ENCORE 2 study', Antimicrobial Agents and Chemotherapy, 56, pp. 1427 - 1433, http://dx.doi.org/10.1128/AAC.05599-11
,2012, 'Plasma HIV Viral Rebound following Protocol-Indicated Cessation of ART Commenced in Primary and Chronic HIV Infection', PLoS ONE, 7, pp. Article numbere43754, http://dx.doi.org/10.1371/journal.pone.0043754
,2012, 'Reclassification of risk of death with the knowledge of D-dimer in a cohort of treated HIV-infected individuals', AIDS, 26, pp. 1707 - 1717, http://dx.doi.org/10.1097/QAD.0b013e328355d659
,2012, 'The influence of HLA supertype on thymidine analogue associated with low peripheral fat in HIV.', AIDS, 26, pp. 2337 - 2344, http://dx.doi.org/10.1097/QAD.0b013e32835ab213
,2012, 'Two patterns of cerebral metabolite abnormalities are detected on proton magnetic resonance spectroscopy in HIV-infected subjects commencing antiretroviral therapy.', Neuroradiology, 54, pp. 1331 - 1339, http://dx.doi.org/10.1007/s00234-012-1061-5
,2011, 'Genotypic resistance at viral rebound among patients who received lopinavir/ritonavir-based or efavirenz-based first antiretroviral therapy in South Africa', Journal of Acquired Immune Deficiency Syndromes, 58, pp. 304 - 308, http://dx.doi.org/10.1097/QAI.0b013e3182278c29
,2011, 'Hyaluronic acid levels predict increased risk of non-AIDS death in hepatitis-coinfected persons interrupting antiretroviral therapy in the SMART study', Antiviral Therapy, 16, pp. 667 - 675, http://dx.doi.org/10.3851/IMP1815
,2011, 'Haemoglobin and anaemia in the SMART study', Antiviral Therapy, 16, pp. 329 - 337, http://dx.doi.org/10.3851/IMP1746
,2011, 'Higher levels of CRP, D-dimer, IL-6, and hyaluronic acid before initiation of antiretroviral therapy (ART) are associated with increased risk of AIDS or death', Journal of Infectious Diseases, 203, pp. 1637 - 1646, http://dx.doi.org/10.1093/infdis/jir134
,2011, 'Resumption of HIV replication is associated with monocyte/macrophage derived cytokine and chemokine changes: results from a large international clinical trial', AIDS, 25, pp. 1207 - 1217, http://dx.doi.org/10.1097/QAD.0b013e3283471f10
,2011, 'An Ad5-vectored HIV-1 vaccine elicits cell-mediated immunity but does not affect disease progression in HIV-1-infected male subjects: Results from a randomized placebo-controlled trial (The step study)', Journal of Infectious Diseases, 203, pp. 765 - 772, http://dx.doi.org/10.1093/infdis/jiq114
,2011, 'N-terminal-proB-type natriuretic peptide predicts cardiovascular disease events in HIV-infected patients', AIDS, 25, pp. 651 - 657, http://dx.doi.org/10.1097/QAD.0b013e32834404a1
,2011, 'Boosted protease inhibitors and the electrocardiographic measures of QT and PR durations', AIDS, 25, pp. 367 - 377, http://dx.doi.org/10.1097/QAD.0b013e328341dcc0
,2011, 'Empirical evaluation of the need for 'on-going consent' in clinical research', AIDS, 25, pp. 107 - 114, http://dx.doi.org/10.1097/QAD.0b013e328340fec7
,2011, 'Lower fat mass and lower bone formation predict greater bone loss with tenofovir in HIV-infected adults', ANTIVIRAL THERAPY, 16, pp. A6 - A7, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000294375900007&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2011, 'The influence of HLA supertype on thymidine analogue induced body composition changes in STEAL', ANTIVIRAL THERAPY, 16, pp. A20 - A21, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000294375900025&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2011, 'Bone turnover markers in HIV disease', AIDS Reviews, 13, pp. 240 - 250, http://www.aidsreviews.com/files/2011_13_4_240-250.pdf
,2011, 'Changes in inflammatory and coagulation biomarkers: A randomized comparison of immediate versus deferred antiretroviral therapy in patients with HIV infection', JAIDS: Journal of Acquired Immune Deficiency Syndromes, 56, pp. 36 - 43, http://dx.doi.org/10.1097/QAI.0b013e3181f7f61a
,2011, 'Hyperlactataemia in HIV-infected subjects initiating antiretroviral therapy in a large randomized study (a substudy of the INITIO trial)', HIV Medicine, 12, pp. 602 - 609, http://dx.doi.org/10.1111/j.1468-1293.2011.00934.x
,2011, 'Impact of lamivudine on HIV and hepatitis B virus-related outcomes in HIV/hepatitis B virus individuals in a randomized clinical trial of antiretroviral therapy in southern Africa', AIDS, 25, pp. 1727 - 1735
,2011, 'Impact of treatment with raltegravir during primary or chronic HIV infection on RNA decay characteristics and the HIV viral reservoir', AIDS, 25, pp. 2069 - 2078, http://dx.doi.org/10.1097/QAD.0b013e32834b9658
,2011, 'Inflammation predicts changes in high-density lipoprotein particles and apolipoprotein A1 following initiation of antiretroviral therapy', AIDS, 25, pp. 2133 - 2142, http://dx.doi.org/10.1097/QAD.0b013e32834be088
,2011, 'Intensification of antiretroviral therapy with raltegravir or addition of hyperimmune bovine colostrum in HIV-infected patients with suboptimal CD4 + T-cell response: A randomized controlled trial', Journal of Infectious Diseases, 204, pp. 1532 - 1540, http://jid.oxfordjournals.org/content/204/10/1532
,2011, 'Pharmacokinetics of plasma lopinavir/ritonavir following the administration of 400/100 mg, 200/150 mg and 200/50 mg twice daily in HIV-negative volunteers', Journal of Antimicrobial Chemotherapy, 66, pp. 635 - 640, http://dx.doi.org/10.1093/jac/dkq468
,2011, 'Plasma levels of soluble CD14 independently predict mortality in HIV infection', Journal of Infectious Diseases, 203, pp. 780 - 790, http://dx.doi.org/10.1093/infdis/jiq118
,2011, 'Predictors of bacterial pneumonia in Evaluation of Subcutaneous Interleukin-2 in a Randomized International Trial (ESPRIT)', HIV Medicine, 12, pp. 219 - 227, http://dx.doi.org/10.1111/j.1468-1293.2010.00875.x
,2011, 'Predictors of limb fat gain in HIV positive patients following a change to tenofovir-emtricitabine or Abacavir-Lamivudine', PLoS One, 6, pp. Article number e26885, http://dx.doi.org/10.1371/journal.pone.0026885
,2011, 'Prevalence and prognostic significance of ECG abnormalities in HIV-infected patients: Results from the Strategies for Management of Antiretroviral Therapy study', Journal of Electrocardiology, 44, pp. 779 - 785, http://dx.doi.org/10.1016/j.jelectrocard.2010.10.027
,2011, 'Prospective evidence that HIV lipoatrophy and visceral adiposity are partially independent processes', Open Access Journal of Clinical Trials, 3, pp. 1 - 7, http://dx.doi.org/10.2147/OAJCT.S14359
,2011, 'Surveillance of illness associated with pandemic (H1N1) 2009 virus infection among adults using a global clinical site netwok approach: The INSIGHT FLU 002 and FLU 003 studies', Vaccine, 29, pp. B56 - B62
,2011, 'The development of an expert system to predict virological response to HIV therapy as part of an online treatment support tool', AIDS, 25, pp. 1855 - 1863, http://dx.doi.org/10.1097/QAD.0b013e328349a9c2
,2010, 'Smoking-Related Health Risks Among Persons With HIV in the Strategies for Management of Antiretroviral Therapy Clinical Trial', AMERICAN JOURNAL OF PUBLIC HEALTH, 100, pp. 1896 - 1903, http://dx.doi.org/10.2105/AJPH.2009.188664
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