By Scientia Professor Anthony D Kelleher

Journal articles

Sasson SC; Kelleher AD, 2014, 'Site-specific host gene modification by zinc finger nucleases: pointing the way to drug free control of HIV-1?', Clinical and Translational Immunology, 3, pp. e19, http://dx.doi.org/10.1038/cti.2014.12

Achhra AC; Boyd MA; Law MG; Matthews GV; Kelleher AD; Cooper DA; Han A, 2014, 'Moving away from ritonavir, abacavir, tenofovir, and efavirenz (RATE) - Agents that concern prescribers and patients: A feasibility study and call for a trial', PLoS ONE, 9, pp. e99530, http://dx.doi.org/10.1371/journal.pone.0099530

Kelleher AD, 2014, 'Promoter targeted small RNAs: stabilising viral reservoirs', MICROBIOLOGY AUSTRALIA, 35, pp. 103 - 104, http://dx.doi.org/10.1071/MA14033

Haskelberg H; Cordery DV; Amin J; Kelleher AD; Cooper DA; Emery S; Post J, 2014, 'HLA Alleles association with changes in bone mineral density in HIV-1-infected adults changing treatment to tenofovir-emtricitabine or abacavir-lamivudine', PLoS ONE, 9, pp. e93333, http://dx.doi.org/10.1371/journal.pone.0093333

Tong WWY; Hillman RJ; Kelleher AD; Grulich AE; Carr A, 2014, 'Anal intraepithelial neoplasia and squamous cell carcinoma in HIV-infected adults', HIV Medicine, 15, pp. 65 - 76, http://dx.doi.org/10.1111/hiv.12080

Amin J; Law MG; Puls R; Kelleher A; Cooper DA; Emery S; Han A, 2014, 'Comparison of central and local HIV-1 RNA quantification from two international clinical trials', AIDS, 28, pp. 2480 - 2483, http://dx.doi.org/10.1097/QAD.0000000000000461

Amin J; Becker S; Belloso W; Boffito M; Cooper D; Crabtree-Ramirez B; Duncombe C; Emery S; Foulkes S; Hill A; Jessen H; Kumar S; Lee MP; Losso M; Nwizu C; Phanuphak P; Ripin D; Read T; Rooney J; Schaffer K; Shahar E; Winston A; Wolff M; Young B; Abela C; Boyd M; Carey D; Clarke A; Courtney-Vega K; Dazo C; Delfino M; Donaldson A; Espinosa N; Johannesen T; Kaew-On P; Lin E; Moricz A; Taylor J; Phanupak P; Puls RL; Pussadee K; Sutheerasak P; Tomkins L; Ubolyam S; Shah Bin Raja Azwa RI; Bissio E; Calanni L; Casiro A; Chetchotisakd P; Contarelli J; Doong N; Elliott J; Gazzard B; Kelly M; Del Carmen Luna N; Lupo S; Messina OG; Mohapi L; Moore R; Nolan D; Orrell C; Perez C; Pett S; Rockstroh J; Supparatpinyo K; Smith D; Villanueva JA; Vlahakis E; Kelleher T; Cunningham P; Merlin K; Yeung J; Shaik A; Fsadni B; Carrera A; Lograsso M; Gulick R; Crabtree-Ramiraz B; Winston E; Dunn D; Dolan M; Cooper D; Kelleher A, 2014, 'Efficacy of 400 mg efavirenz versus standard 600 mg dose in HIV-infected, antiretroviral-naive adults (ENCORE1): A randomised, double-blind, placebo-controlled, non-inferiority trial', The Lancet, 383, pp. 1474 - 1482, http://dx.doi.org/10.1016/S0140-6736(13)62187-X

Streeck H; Lu R; Beckwith N; Milazzo M; Liu M; Routy JP; Little S; Jessen H; Kelleher AD; Hecht F; Sekaly RP; Alter G; Heckerman D; Carrington M; Rosenberg ES; Altfeldc M, 2014, 'Emergence of individual HIV-specific CD8 T cell responses during primary HIV-1 infection can determine long-term disease outcome', Journal of Virology, 88, pp. 12793 - 12801, http://dx.doi.org/10.1128/JVI.02016-14

Pham QD; Wilson DP; Law MG; Kelleher AD; Zhang L; Han A, 2014, 'Global burden of transmitted HIV drug resistance and HIV-exposure categories: A systematic review and meta-analysis', AIDS, 28, pp. 2751 - 2762, http://dx.doi.org/10.1097/QAD.0000000000000494

Murray JM; Zaunders JJ; McBride KL; Xu Y; Bailey M; Suzuki K; Cooper DA; Emery S; Kelleher AD; Koelsch KK, 2014, 'HIV DNA subspecies persist in both activated and resting memory CD4⁺ T cells during antiretroviral therapy', Journal of Virology, 88, pp. 3516 - 3526, http://dx.doi.org/10.1128/JVI.03331-13

Williams JP; Hurst J; Stöhr W; Robinson N; Brown H; Fisher M; Kinloch S; Cooper D; Schechter M; Tambussi G; Fidler S; Carrington M; Babiker A; Weber J; Koelsch KK; Kelleher AD; Phillips RE; Frater J, 2014, 'HIV-1 DNA predicts disease progression and post-treatment virological control', eLife, 3, pp. e03821, http://dx.doi.org/10.7554/eLife.03821

Ana-Sosa-Batiz F; Johnston APR; Liu H; Center RJ; Rerks-Ngarm S; Pitisuttithum P; Nitayaphan S; Kaewkungwal J; Kim JH; Michael NL; Kelleher AD; Stratov I; Kent SJ; Kramski M, 2014, 'HIV-specific antibody-dependent phagocytosis matures during HIV infection', Immunology and Cell Biology, 92, pp. 679 - 687, http://dx.doi.org/10.1038/icb.2014.42

Seddiki N; Cook L; Hsu DC; Phetsouphanh C; Brown K; Xu Y; Kerr SJ; Cooper DA; Munier CML; Pett S; Ananworanich J; Zaunders J; Kelleher AD, 2014, 'Human antigen-specific CD4⁺CD25⁺CD134⁺CD39⁺ T cells are enriched for regulatory T cells and comprise a substantial proportion of recall responses', European Journal of Immunology, 44, pp. 1644 - 1661, http://dx.doi.org/10.1002/eji.201344102

Kuang XT; Li X; Anmole G; Mwimanzi P; Shahid A; Le AQ; Chong L; Qian H; Miura T; Markle T; Baraki B; Connick E; Daar ES; Jessen H; Kelleher AD; Little S; Markowitz M; Pereyra F; Rosenberg ES; Walker BD; Ueno T; Brumme ZL; Brockman MA; Walker B, 2014, 'Impaired Nef function is associated with early control of HIV-1 viremia', Journal of Virology, 88, pp. 10200 - 10213, http://dx.doi.org/10.1128/JVI.01334-14

Hsu DC; Kerr SJ; Thongpaeng P; Iampornsin T; Pett SL; Zaunders JJ; Avihingsanon A; Ubolyam S; Ananworanich J; Kelleher AD; Cooper DA, 2014, 'Incomplete restoration of Mycobacterium tuberculosis-specific-CD4 T cell responses despite antiretroviral therapy', Journal of Infection, 68, pp. 344 - 354, http://dx.doi.org/10.1016/j.jinf.2013.11.016

Swaminathan S; Kelleher AD, 2014, 'MicroRNA modulation of key targets associated with T cell exhaustion in HIV-1 infection', Current Opinion in HIV and AIDS, 9, pp. 464 - 471, http://dx.doi.org/10.1097/COH.0000000000000089

Fernandez CS; Kelleher AD; Finlayson R; Godfrey DI; Kent SJ, 2014, 'NKT cell depletion in humans during early HIV infection', Immunology and Cell Biology, 92, pp. 578 - 590, http://dx.doi.org/10.1038/icb.2014.25

Phetsouphanh C; Xu Y; Bailey M; Pett S; Zaunders J; Seddiki N; Kelleher AD, 2014, 'Ratios of effector to central memory antigen-specific CD4 + T cells vary with antigen exposure in HIV+ patients', Immunology and Cell Biology, 92, pp. 384 - 388, http://dx.doi.org/10.1038/icb.2013.101

Pantazis N; Porter K; Costagliola D; De Luca A; Ghosn J; Guiguet M; Johnson AM; Kelleher AD; Morrison C; Thiebaut R; Wittkop L; Touloumi G, 2014, 'Temporal trends in prognostic markers of HIV-1 virulence and transmissibility: An observational cohort study', The Lancet HIV, 1, pp. e119 - e126, http://dx.doi.org/10.1016/S2352-3018(14)00002-2

Kelleher AD, 2014, 'Promoter targeted small RNAs: stabilising viral reservoirs', Microbiology Australia, 10, pp. 1071

Murray JM; Zaunders JJ; Koelsch KK; Natarajan V; Badralmaa Y; McBride K; Carrera A; Cooper DA; Emery S; Kelleher AD, 2013, 'Short communication: HIV blips while on antiretroviral therapy can indicate consistently detectable viral levels due to assay underreporting', AIDS Research and Human Retroviruses, 29, pp. 1621 - 1625, http://dx.doi.org/10.1089/aid.2013.0132

Vaidya SA; Streeck H; Beckwith N; Ghebremichael M; Pereyra F; Kwon DS; Addo MM; Rychert J; Routy JP; Jessen H; Kelleher AD; Hecht F; Sekaly RP; Carrington M; Walker BD; Allen TM; Rosenberg ES; Altfeld M, 2013, 'Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection', Retrovirology, 10, http://dx.doi.org/10.1186/1742-4690-10-139

Hsu DC; Kerr SJ; Iampornsin T; Pett SL; Avihingsanon A; Thongpaeng P; Zaunders JJ; Ubolyam S; Ananworanich J; Kelleher AD; Cooper DA, 2013, 'Restoration of CMV-Specific-CD4 T Cells with ART Occurs Early and Is Greater in Those with More Advanced Immunodeficiency', PLoS ONE, 8, http://dx.doi.org/10.1371/journal.pone.0077479

Phetsouphanh C; Xu Y; Amin J; Seddiki N; Procopio F; Sekaly RP; Zaunders JJ; Kelleher AD, 2013, 'Characterization of Transcription Factor Phenotypes within Antigen-Specific CD4+ T Cells Using Qualitative Multiplex Single-Cell RT-PCR', PLoS ONE, 8, http://dx.doi.org/10.1371/journal.pone.0074946

McBride K; Xu Y; Bailey M; Seddiki N; Suzuki K; Murray JM; Gao Y; Yan C; Cooper DA; Kelleher AD; Koelsch KK; Zaunders J, 2013, 'The majority of HIV type 1 DNA in circulating CD4⁺ T lymphocytes is present in non-gut-homing resting memory CD4⁺ T cells', AIDS Research and Human Retroviruses, 29, pp. 1330 - 1339, http://dx.doi.org/10.1089/aid.2012.0351

Kent SJ; Reece JC; Petravic J; Martyushev A; Kramski M; De Rose R; Cooper DA; Kelleher AD; Emery S; Cameron PU; Lewin SR; Davenport MP, 2013, 'The search for an HIV cure: Tackling latent infection', The Lancet Infectious Diseases, 13, pp. 614 - 621, http://dx.doi.org/10.1016/S1473-3099(13)70043-4

French MA; Center RJ; Wilson KM; Fleyfel I; Fernandez S; Schorcht A; Stratov I; Kramski M; Kent SJ; Kelleher AD, 2013, 'Isotype-switched immunoglobulin G antibodies to HIV Gag proteins may provide alternative or additional immune responses to 'protective' human leukocyte antigen-B alleles in HIV controllers', AIDS, 27, pp. 519 - 528, http://dx.doi.org/10.1097/QAD.0b013e32835cb720

Suzuki K; Hattori S; Marks K; Ahlenstiel C; Maeda Y; Ishida T; Millington M; Boyd M; Symonds G; Cooper DA; Okada S; Kelleher AD, 2013, 'Promoter Targeting shRNA Suppresses HIV-1 Infection In vivo Through Transcriptional Gene Silencing', Molecular Therapy Nucleic Acids, 2, pp. e137, http://dx.doi.org/10.1038/mtna.2013.64

Tu E; Swenson LC; Land S; Pett S; Emery S; Marks K; Kelleher AD; Kaye S; Kaiser R; Schuelter E; Harrigan R, 2013, 'Results of external quality assessment for proviral DNA testing of HIV tropism in the Maraviroc switch collaborative study', Journal of Clinical Microbiology, 51, pp. 2063 - 2071, http://dx.doi.org/10.1128/JCM.00510-13

Mee Ling Munier C; Kelleher AD; Kent SJ; De Rose R, 2013, 'The role of T cell immunity in HIV-1 infection', Current Opinion in Virology, 3, pp. 438 - 446, http://dx.doi.org/10.1016/j.coviro.2013.05.009

Gilmore JB; Kelleher AD; Cooper DA; Murray JM, 2013, 'Explaining the determinants of first phase HIV decay dynamics through the effects of stage-dependent drug action', PLoS Computational Biology, 9, pp. e1002971 (11pp), http://dx.doi.org/10.1371/journal.pcbi.1002971

Swaminathan S; Murray DD; Kelleher AD, 2013, 'Mirnas and HIV: Unforeseen Determinants Of Host-Pathogen Interaction', Immunological Reviews, 254, pp. 265 - 280, http://dx.doi.org/10.1111/imr.12077Document

Porter K; Ewings FM; Ramjee G; Cooper DA; Fisher M; Schechter MT; Tambussi G; Kinloch-De Loes S; Miro J; Kelleher AD; Mcclure MO; Gabriel M; Phillips R; Weber J; Babiker AG, 2013, 'Short-course antiretroviral therapy in primary HIV infection', New England Journal of Medicine, 368, pp. 207 - 217, http://dx.doi.org/10.1056/NEJMoa1110039

Xu Y; Weatherall CJ; Bailey MR; Alcantara S; De Rose R; Estaquier J; Wilson KM; Suzuki K; Corbeil J; Cooper DA; Kent SJ; Kelleher AD; Zaunders J, 2013, 'Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques', Journal of Virology, 87, pp. 3760 - 3773, http://dx.doi.org/10.1128/JVI.02497-12

Seddiki N; Phetsouphanh C; Swaminathan S; Xu Y; Rao S; Li J; Sutcliffe E; Denyer G; Finlayson R; Gelgor L; Cooper DA; Zaunders J; Kelleher AD, 2013, 'The microRNA-9/B-lymphocyte-induced maturation protein-1/IL-2 axis is differentially regulated in progressive HIV infection', European Journal of Immunology, 43, pp. 510 - 520, http://dx.doi.org/10.1002/eji.201242695

, 2012, 'Track A Basic Science', Journal of the International AIDS Society, 15, http://dx.doi.org/10.7448/ias.15.5.18438

Kikuchi T; Iwabu Y; Kawana-Tachikawa A; Koga M; Hosoya N; Nomura S; Brumme ZL; Jessen H; Kelleher A; Markowitz M; Pereyra F; Trocha A; Walker BD; Iwamoto A; Tokunaga K; Miura T, 2012, 'Anti-APOBEC3G activity of HIV-1 Vif protein from elite controllers is attenuated compared to those from untreated chronic progressors or those from individuals with acute infection', JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 15, pp. 19 - 19, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310588200043&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

French M; Center R; Wilson K; Fleyfel I; Fernandez S; Kelleher A, 2012, 'Natural control of HIV infection is associated with an isotype switched IgG antibody response to HIV core antigens in patients with 'non-protective' HLA-B alleles', JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 15, pp. 5 - 6, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310588200010&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Kelleher AD; Cooper DA, 2012, 'Acute HIV infection', , pp. 77 - 88, http://dx.doi.org/10.1016/B978-1-4557-0695-2.00006-7

Jarrin I; Pantazis N; Gill MJ; Geskus R; Perez-Hoyos S; Meyer L; Prins M; Touloumi G; Johnson A; Hamouda O; de Olalla PG; Porter K; del Amo J; CASCADE Collaboration in EuroCoord , 2012, 'Uptake of combination antiretroviral therapy and HIV disease progression according to geographical origin in seroconverters in Europe, Canada, and Australia.', Clin Infect Dis, 54, pp. 111 - 118, http://dx.doi.org/10.1093/cid/cir814

Hsu DC; Zaunders J; Plit ML; Leeman C; Ip S; Iampornsin T; Pett SL; Bailey MR; Amin J; Ubolyam S; Avihingsanon A; Ananworanich J; Ruxrungtham K; Cooper DA; Kelleher AD, 2012, 'A novel assay detecting recall response to Mycobacterium tuberculosis: Comparison with existing assays', Tuberculosis, 92, pp. 321 - 327, http://dx.doi.org/10.1016/j.tube.2012.03.008

Lodi S; Meyer L; Kelleher AD; Rosinska M; Ghosn J; Sannes M; Porter K, 2012, 'Immunovirologic Control 24 Months After Interruption of Antiretroviral Therapy Initiated Close to HIV Seroconversion', Annals of Internal Medicine, 172, pp. 1252 - 1255, http://dx.doi.org/10.1001/archinternmed.2012.2719

Sasson SC; Zaunders J; Seddiki N; Mcbride K; Koelsch KK; Merlin KM; Smith DE; Cooper DA; Kelleher AD; Bailey MR, 2012, 'Progressive activation of CD127+132- recent thymic emigrants into terminally differentiated CD127-132+ T-cells in HIV-1 infection', PLoS One, 7, pp. e31148, http://dx.doi.org/10.1371/journal.pone.0031148

Kramski M; Schorcht A; Johnston APR; Lichtfuss G; Jegaskanda S; De rose R; Stratov I; Kelleher AD; French MA; Center RJ; Jaworowski A; Kent SJ, 2012, 'Role of monocytes in mediating HIV-specific antibody-dependent cellular cytotoxicity', Journal of Immunological Methods, 384, pp. 51 - 61, http://dx.doi.org/10.1016/j.jim.2012.07.006

Wren LH; Chung AW; Isitman G; Kelleher AD; Parsons MS; Amin J; Cooper DA; Stratov SI; Navis M; Kent SJ, 2012, 'Specific antibody-dependent cellular cytotoxicity responses associated with slow progression of HIV infection', Immunology, 138, pp. 116 - 123, http://dx.doi.org/10.1111/imm.12016

Cordery D; Martin A; Kelleher AD; Emery S; Cooper DA, 2012, 'The influence of HLA supertype on thymidine analogue associated with low peripheral fat in HIV.', AIDS, 26, pp. 2337 - 2344, http://dx.doi.org/10.1097/QAD.0b013e32835ab213

Swaminathan S; Kelleher AD; Murray DD, 2012, 'The role of microRNAs in HIV-1 pathogenesis and therapy', AIDS, 26, pp. 1325 - 1334, http://dx.doi.org/10.1097/QAD.0b013e328352adca

Brockman M; Chopera DR; Olvera A; Brumme C; Sela J; Markle TJ; Martin EPG; Carlson JM; Le AQ; Mcgovern R; Cheung PK; Kelleher AD; Jessen H; Markowitz M; Rosenberg E; Frahm N; Sanchez J; Mallal S; John M; Harrigan PR; Heckerman D; Brander C; Walker BD; Brummea ZL, 2012, 'Uncommon pathways of immune escape attenuate HIV-1 integrase replication capacity', Journal of Virology, 86, pp. 6913 - 6923, http://dx.doi.org/10.1128/JVI.07133-11

Jaffe HW; De Stavola BL; Carpenter LM; Porter K; Cox DR; CASCADE Collaboration , 2011, 'Immune reconstitution and risk of Kaposi sarcoma and non-Hodgkin lymphoma in HIV-infected adults.', AIDS, 25, pp. 1395 - 1403, http://dx.doi.org/10.1097/QAD.0b013e3283489c8b

Matthews PC; Leslie AJ; Katzourakis A; Crawford H; Payne R; Prendergast A; Power K; Kelleher AD; Klenerman P; Carlson J; Heckerman D; Ndung'u T; Walker BD; Allen TM; Pybus OG; Goulder PJR, 2011, 'HLA footprints on human immunodeficiency virus type 1 are associated with interclade polymorphisms and intraclade phylogenetic clustering', Journal of Virology, 85, pp. 4635, http://dx.doi.org/10.1128/JVI.00375-11

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