Dr Jennifer Snaith is an Endocrinologist and Research Fellow based at the Garvan Institute of Medical Research where she conducts clinical trials in type 1 diabetes as part of the AUSTAG group. Her career mission is to improve the lives of people living with type 1 diabetes through clinical service, advocacy and innovative research. 

She is a Staff Specialist Endocrinologist at St Vincent's Hospital, and established with her team (Marhava/Lum/Higgins), the Diabetes in Youth (DIY) service in 2021. Her research activities are clinically based and relate to type 1 diabetes, insulin resistance, adjunctive therapies and cardiometabolic risk.

During her PhD candidature (primary supervisor Greenfield) Dr Snaith conducted the INTIMET study (INsulin resistance in type 1 diabetes managed with METformin) and was a recipient of the National Health and Medical Research Council (NHMRC) Post Graduate Scholarship, and Diabetes Australia top up scholarship. The INTIMET study was a placebo controlled randomised controlled clinical examining the impact of metformin on hepatic and muscle insulin resistance, assessed using hyperinsulinaemic euglycaemic clamps.

The RESET1 study (Reducing Cardiometabolic Risk with Semaglutide in Type 1 Diabetes) is the second clinical trial from the AUSTAG group. Snaith was awarded the Diabetes Australia Coghlan Award for Emerging Researchers, and the Rebecca Davies Fellowship from JDRF Australia to conduct this randomised placebo controlled clinical trial to examine the effect of semaglutide on cardiovascular risk in adults with type 1 diabetes. Trial registration: https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=386649&isReview=true

The TIRTLE study (Tirzepatide in Type 1 Diabetes: Cardiometabolic Effects) is a tirzepatide in type 1 diabetes placebo controlled trial (due for completion Dec 2024). Trial registration: https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=386985&isReview=true

Prof Jerry Greenfield and Dr Snaith established the Garvan Institute 'Australian Type 1 Diabetes Mellitus Adjuncts Group' (AUSTAG). The AUSTAG mission is to prolong the life of Australians living with type 1 diabetes by preventing cardiovascular disease through novel repurposing of cardioprotective medications. AUSTAG specialise in the conduct of clinical trials in type 1 diabetes. These studies include detailed mechanistic studies, to phenotype metabolic health in type 1 diabetes, and the physiological impacts of adjunctive therapies on cardiometabolic health in type 1 diabetes.