Select Publications
Books
, 2012, School of Medical Sciences Honours Course Manual, Polly P; Hardman CD; Finch AM, (eds.), School of Medical Sciences, Faculty of Medicine, UNSW, Sydney, Australia
, 2011, School of Medical Sciences Honours Course Manual, Polly P; Hardman CD; Finch AM, (eds.), School of Medical Sciences, Faculty of Medicine, UNSW, Sydney, Australia
Book Chapters
2005, 'Ligand binding, activation and agonist trafficking', in Perez DM (ed.), The Adrenergic Receptors in the 21st Century, Humana Press, New Jersey, NJ, pp. 25 - 86
,Journal articles
2023, 'Gene expression analyses of TAS1R taste receptors relevant to the treatment of cardiometabolic disease', Chemical Senses, 48, http://dx.doi.org/10.1093/chemse/bjad027
,2022, 'Orphan GPR146: an alternative therapeutic pathway to achieve cholesterol homeostasis?', Trends in Endocrinology and Metabolism, 33, pp. 481 - 492, http://dx.doi.org/10.1016/j.tem.2022.04.008
,2022, 'Characterisation of bis(4-aminoquinoline)s as α
2021, 'Critically evaluating sweet taste receptor expression and signaling through a molecular pharmacology lens', FEBS Journal, 288, pp. 2660 - 2672, http://dx.doi.org/10.1111/febs.15768
,2021, 'Orphan receptor GPR37L1 remains unliganded', Nature Chemical Biology, 17, pp. 383 - 386, http://dx.doi.org/10.1038/s41589-021-00748-z
,2020, 'Vicinal difluorination as a C=C surrogate: An analog of piperine with enhanced solubility, photostability, and acetylcholinesterase inhibitory activity', Beilstein Journal of Organic Chemistry, 16, pp. 2663 - 2670, http://dx.doi.org/10.3762/BJOC.16.216
,2020, 'Orphan G protein-coupled receptor, GPR37L1: pharmacological toolbox empty once again', , http://dx.doi.org/10.1101/2020.09.11.290486
,2020, 'Vicinal difluorination as a C=C surrogate: an analog of piperine with enhanced solubility, photostability, and acetylcholinesterase inhibitory activity', , http://dx.doi.org/10.3762/bxiv.2020.93.v1
,2018, 'Design, Synthesis, and Evaluation of N- and C-Terminal Protein Bioconjugates as G Protein-Coupled Receptor Agonists', Bioconjugate Chemistry, 29, pp. 403 - 409, http://dx.doi.org/10.1021/acs.bioconjchem.7b00716
,2017, 'Template selection and refinement considerations for modelling aminergic GPCR-ligand complexes', Journal of Molecular Graphics and Modelling, 76, pp. 488 - 503, http://dx.doi.org/10.1016/j.jmgm.2017.07.030
,2017, 'Homobivalent conjugation increases the allosteric effect of 9-aminoacridine at the α
2014, 'Human α
2014, 'An aspartate in the second extracellular loop of the α
2014, 'Expression of adrenoceptor subtypes in preterm piglet heart is different to term heart', PLoS ONE, 9, http://dx.doi.org/10.1371/journal.pone.0092167
,2013, '5-HT1A receptor pharmacophores to screen for off-target activity of á1-adrenoceptor antagonists', Journal of Computer - Aided Molecular Design, 27, pp. 305 - 319, http://dx.doi.org/10.1007/s10822-013-9647-5
,2013, 'a1-Adrenoceptor and serotonin 5-HT1A receptor affinity of homobivalent 4-aminoquinoline compounds: An investigation of the effect of linker length', Biochemical Pharmacology, 85, pp. 1534 - 1541, http://dx.doi.org/10.1016/j.bcp.2013.03.010
,2011, 'A novel structural framework for á1a/d-adrenoceptor selective antagonists identified using subtype selective pharmacophores', PLoS One, 6, pp. e19695, http://dx.doi.org/10.1371/journal.pone.0019695
,2008, 'Effect of controlled alterations in maternal dietary retinol on foetal and neonatal retinol status and pregnancy outcome in pigs', Livestock Science, 118, pp. 247 - 254
,2008, 'Peripheral changes above and below injury level lead to prolonged vascular responses following high spinal cord injury', American Journal of Physiology - Heart and Circulatory Physiology, 294, pp. H785 - H792, http://dx.doi.org/10.1152/ajpheart.01002.2007
,2008, 'Wide turn diversity in protein transmembrane helices implications for G-protein-coupled receptor and other polytopic membrane protein structure and function', Molecular Pharmacology, 73, pp. 1092 - 1104, http://dx.doi.org/10.1124/mol.107.043042
,2007, 'Glucocorticoid exposure and tissue gene expression of 11â HSD-1, 11 â HSD-2, and glucocorticoid receptor in a porcine model of differential fetal growth', Reproduction, 133, pp. 653 - 661
,2006, 'The α
2006, 'Cardiac overexpression of the alpha(1A)-adrenergic receptor limits post-infarct ventricular remodeling and dysfunction, and improves survival', Journal of Molecular and Cellular Cardiology, 41, pp. 735 - 735
,2006, 'The alpha(1D)-adrenergic receptor: Cinderella or ugly stepsister', Molecular Pharmacology, 69, pp. 1 - 4
,2006, 'Transgenic alpha(1A)-adrenergic activation limits post-infarct ventricular remodeling and dysfunction and improves survival', Cardiovascular Research, 71, pp. 735 - 743
,2005, 'The effect of fetal pig size and stage of gestation on tissue fatty acid metabolism and profile', Reproduction, 129, pp. 757 - 763
,2004, 'Genetic enhancement of ventricular contractility protects against pressure-overload-induced cardiac dysfunction', Journal of Molecular and Cellular Cardiology, 37, pp. 979 - 987
,2004, 'Placental transport of leucine in a porcine model of low birth weight', Reproduction, 128, pp. 229 - 235
,2004, 'Synthesis and biological evaluation of bicyclic and tricyclic substituted nortropan derivatives: discovery of a novel selective Ą1D-adrenergic receptor ligand', Bioorganic and Medicinal Chemistry, 12, pp. 5639 - 5650
,2003, 'Sodium transport across the chorioallantoic membrane of porcine placenta involves the epithelial sodium channel (ENaC)', The Journal of Physiology, 547, pp. 849 - 857, http://dx.doi.org/10.1113/jphysiol.2002.031153
,2002, 'Patterns of fetal growth within Large White x Landrace and Chinese Meishan gilt litters at three stages of gestation', Reproduction, Fertility and Development, 14, pp. 419 - 425, http://dx.doi.org/10.1071/RD01131
,2001, 'Causes and consequences of fetal growth retardation in pigs.', Reproduction (Cambridge, England) Supplement, 58, pp. 233 - 246
,2001, 'The effect of feeding salmon oil to sows throughout pregnancy on pre-weaning mortality of piglets', Animal Science, 73, pp. 489 - 500, http://dx.doi.org/10.1017/s135772980005846x
,1999, 'Low-molecular-weight peptidic and cyclic antagonists of the receptor for the complement factor C5a', Journal of Medicinal Chemistry, 42, pp. 1965 - 1974, http://dx.doi.org/10.1021/jm9806594
,1999, 'Effects of a new C5a receptor antagonist on C5a- and endotoxin-induced neutropenia in the rat', British Journal of Pharmacology, 126, pp. 551 - 554, http://dx.doi.org/10.1038/sj.bjp.0702338
,1999, 'Pharmacological characterization of antagonists of the C5a receptor', British Journal of Pharmacology, 128, pp. 1461 - 1466, http://dx.doi.org/10.1038/sj.bjp.0702938
,1999, 'The influence of Lys68 in decapeptide agonists of C5a on C5a receptor binding, activation and selectivity', Journal of Peptide Research, 53, pp. 8 - 17, http://dx.doi.org/10.1111/j.1399-3011.1999.tb01612.x
,1998, 'Small molecular probes for G-protein-coupled C5a receptors: Conformationally constrained antagonists derived from the C terminus of the human plasma protein C5a', Journal of Medicinal Chemistry, 41, pp. 3417 - 3425, http://dx.doi.org/10.1021/jm9800651
,1997, 'Biologically active conformer of the effector region of human C5a and modulatory effects of N-terminal receptor binding determinants on activity', Journal of Medicinal Chemistry, 40, pp. 877 - 884, http://dx.doi.org/10.1021/jm960727r
,1997, 'Molecular Adjuvant Effects of a Conformationally Biased Agonist of Human C5a Anaphylatoxin', Journal of Immunology, 158, pp. 1377 - 1382
,1996, 'Conformationally biased analogs of human C5a mediate changes in vascular permeability', Journal of Pharmacology and Experimental Therapeutics, 278, pp. 432 - 440
,1995, 'Decapeptide Agonists of Human C5a: The Relationship between Conformation and Neutrophil Response', Journal of Medicinal Chemistry, 38, pp. 3669 - 3675, http://dx.doi.org/10.1021/jm00018a028
,1995, 'The effect of C5a and U46619 on the isolated, perfused human placental lobule: Development of a method for the online estimation of tissue fluid accumulation', Journal of Pharmacological and Toxicological Methods, 34, pp. 133 - 141, http://dx.doi.org/10.1016/1056-8719(95)00046-3
,1994, 'Reversibility of tachyphylaxis to C5a in guinea pig tissues, perfused human placental lobule, and umbilical artery', Inflammation, 18, pp. 645 - 657, http://dx.doi.org/10.1007/BF01535262
,1994, 'Decapeptide Agonists of Human C5a: The Relationship between Conformation and Spasmogenic and Platelet Aggregatory Activities', Journal of Medicinal Chemistry, 37, pp. 3171 - 3180, http://dx.doi.org/10.1021/jm00045a023
,Conference Papers
2004, 'Genetic enhancenment of ventricular contractility protects against pressure - overload-induced cardiac dysfunction', in Journal of Molecular and Cellular Cardiology, Academic Press Ltd Elsevier Science Ltd, London, England, pp. 363 - 364, presented at Journal of Molecular and Cellular Cardiology
,2003, 'Relationship between hepatic fatty acid profile and delta-6-desaturase gene expression in different sized pig fetuses at three stages of gestation.', in PEDIATRIC RESEARCH, INT PEDIATRIC RESEARCH FOUNDATION, INC, ENGLAND, BRIGHTON, pp. 16A - 16A, presented at 2nd World Congress on Dietal Origins of Adult Disease, ENGLAND, BRIGHTON, 07 June 2003 - 10 June 2003, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000183333800113&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
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