By Associate Professor David Anthony Jacques

Preprints

Brown AW; Al-Izzi SC; Parker JL; Hertel S; Jacques DA; Kusumaatmaja H; Morris RG, 2025, Capillarity Reveals the Role of Capsid Geometry in HIV Nuclear Translocation, http://dx.doi.org/10.48550/arxiv.2510.26357

Lau D; Walsh J; Peng W; Shah V; Turville S; Jacques D; Böcking T, 2019, Fluorescence biosensor for real-time interaction dynamics of host proteins with HIV-1 capsid tubes, http://dx.doi.org/10.1101/619841

Mitic I; Michie KA; Jacques DA, Assessing the Validity of Leucine Zipper Constructs Predicted in AlphaFold2, http://dx.doi.org/10.1101/2024.10.14.618350

Dickson CF; Hertel S; Ruan J; Ariotti N; Tuckwell A; Li N; Al-Izzi SC; Sierecki E; Gambin Y; Morris RG; Towers GJ; Böcking T; Jacques DA, Karyopherin mimicry explains how the HIV capsid penetrates nuclear pores, http://dx.doi.org/10.1101/2023.03.23.534032

Alvarez LZ; Govasli ML; Rasaiyaah J; Monit C; Perry SO; Sumner RP; McAlpine-Scott S; Dickson C; Faysal KMR; Hilditch L; Miles RJ; Bibollet-Ruche F; Hahn BH; Boecking T; Pinotsis N; James LC; Jacques DA; Towers GJ, Macrophage activation of cGAS and TRIM5 distinguish pandemic and non-pandemic HIV, http://dx.doi.org/10.1101/2022.01.21.477263

Gupta M; Waltmann C; Renner N; Wang Y; James LC; Jacques DA; Böcking T; Voth GA, Mechanistic Insights into Lenacapavir-Induced Off-Pathway HIV-1 Capsid Assembly, http://dx.doi.org/10.1101/2025.08.13.670175

Faysal KMR; Walsh J; Renner N; Márquez CL; Shah VB; Tuckwell AJ; Christie MP; Parker MW; Turville SG; Towers GJ; James L; Jacques DA; Böcking T, Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure, http://dx.doi.org/10.1101/2022.09.21.508807

Lau D; Walsh JC; Dickson CF; Tuckwell A; Stear JH; Hunter DJB; Bhumkar A; Shah V; Turville SG; Sierecki E; Gambin Y; Böcking T; Jacques DA, Rapid HIV-1 capsid interaction screening using fluorescence fluctuation spectroscopy, http://dx.doi.org/10.1101/2020.11.13.382242

Moustaqil M; Ollivier E; Chiu H-P; Van Tol S; Rudolffi-Soto P; Stevens C; Bhumkar A; Hunter DJB; Freiberg A; Jacques D; Lee B; Sierecki E; Gambin Y, SARS-CoV-2 proteases cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species and the search for reservoir hosts, http://dx.doi.org/10.1101/2020.06.05.135699

Zeng J; Santos AF; Mukadam A; Osswald M; Luptak J; Jacques D; Dickson C; Renner N; Johnson C; Vaysburd M; McEwan WA; Morais-de-Sá E; Clift D; James LC, Substrate-induced clustering activates Trim-Away of pathogens and proteins, http://dx.doi.org/10.1101/2020.07.28.225359

Yu R; Phalora P; Li N; Böcking T; Jacques DA, The Human T-cell Leukemia Virus capsid protein is a potential drug target, http://dx.doi.org/10.1101/2024.09.09.612167

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