Select Publications
Journal articles
2018, 'Barriers and facilitators of appropriate vancomycin use: prescribing context is key', European Journal of Clinical Pharmacology, 74, pp. 1523 - 1529, http://dx.doi.org/10.1007/s00228-018-2525-2
,2018, 'Lactic Acidosis, Metformin Use, and Dose-Response Association', JAMA Internal Medicine, 178, pp. 1428 - 1429, http://dx.doi.org/10.1001/jamainternmed.2018.4448
,2018, 'Clinical pharmacokinetics in kidney disease application to rational design of dosing regimens', Clinical Journal of the American Society of Nephrology, 13, pp. 1254 - 1263, http://dx.doi.org/10.2215/CJN.05150418
,2018, 'Clinical pharmacokinetics in kidney disease: Fundamental principles', Clinical Journal of the American Society of Nephrology, 13, pp. 1085 - 1095, http://dx.doi.org/10.2215/CJN.00340118
,2018, 'Patients' use of mobile health applications: What general practitioners think', Family Practice, 36, pp. 214 - 218, http://dx.doi.org/10.1093/fampra/cmy052
,2018, 'Molecular Determinants for Substrate Interactions with the Glycine Transporter GlyT2', ACS Chemical Neuroscience, 9, pp. 603 - 614, http://dx.doi.org/10.1021/acschemneuro.7b00407
,2018, 'A Multicentre Open-Label Pharmacokinetic-Pharmacodynamic Study of Febuxostat in Patients with Chronic Gout', Proceedings for Annual Meeting of The Japanese Pharmacological Society, WCP2018, http://dx.doi.org/10.1254/jpssuppl.wcp2018.0_po1-11-12
,2017, 'Synthesis and Characterization of Novel Acyl-Glycine Inhibitors of GlyT2', ACS Chemical Neuroscience, 8, pp. 1949 - 1959, http://dx.doi.org/10.1021/acschemneuro.7b00105
,2017, 'Allopurinol: insights from studies of dose–response relationships', Expert Opinion on Drug Metabolism and Toxicology, 13, pp. 449 - 462, http://dx.doi.org/10.1080/17425255.2017.1269745
,2016, 'Glycine transporter2 inhibitors: Getting the balance right', Neurochemistry International, 98, pp. 89 - 93, http://dx.doi.org/10.1016/j.neuint.2015.12.007
,2016, 'Correction: Identification of a 3rd Na+ binding site of the glycine transporter, GlyT2', PLoS ONE, 11, http://dx.doi.org/10.1371/journal.pone.0159896
,2016, 'Identification of a 3rd Na+ binding site of the glycine transporter, GlyT2', PLoS ONE, 11, pp. e0157583, http://dx.doi.org/10.1371/journal.pone.0157583
,2015, 'Molecular Basis for Substrate and Inhibitor Interactions with the Glycine Transporter, GlyT2', FASEB JOURNAL, 29, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000361470504039&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
,2015, 'A Hydrophobic Area of the GABA ρ
2014, 'Glycine transport inhibitors for the treatment of pain', Trends in Pharmacological Sciences, 35, pp. 423 - 430, http://dx.doi.org/10.1016/j.tips.2014.05.006
,2014, 'Lipid inhibitors of high affinity glycine transporters: Identification of a novel class of analgesics', Neurochemistry International, 73, pp. 211 - 216, http://dx.doi.org/10.1016/j.neuint.2013.08.012
,2013, 'Mutagenic analysis of the intracellular portals of the human 5-HT
2013, 'Oleoyl-L-carnitine inhibits glycine transport by GlyT2', British Journal of Pharmacology, 168, pp. 891 - 902, http://dx.doi.org/10.1111/j.1476-5381.2012.02213.x
,2012, 'Differentiating enantioselective actions of GABOB: A possible role for threonine 244 in the binding site of GABA
2012, 'Structurally diverse GABA antagonists interact differently with open and closed conformational states of the ρ
2010, 'Novel structural determinants of single channel conductance and ion selectivity in 5-hydroxytryptamine type 3 and nicotinic acetylcholine receptors', Journal of Physiology, 588, pp. 587 - 596, http://dx.doi.org/10.1113/jphysiol.2009.183137
,2010, 'External divalent cations increase anion-cation permeability ratio in glycine receptor channels', Pflugers Archiv - European Journal of Physiology, 460, pp. 131 - 152, http://dx.doi.org/10.1007/s00424-010-0792-6
,2009, 'Characterization of the effects of charged residues in the intracellular loop on ion permeation in α1 glycine receptor channels', The Journal of Biological Chemistry, 284, pp. 2023 - 2030, http://dx.doi.org/10.1074/jbc.M806618200
,2008, 'Relative impact of residues at the intracellular and extracellular ends of the human GABA(C) rho 1 receptor M2 domain on picrotoxinin activity', European Journal of Pharmacology, 580, pp. 27 - 35
,2008, 'Structural determinants of Ca2+ permeability and conduction in the human 5-hydroxytryptamine type 3A receptor', The Journal of Biological Chemistry, 283, pp. 19301 - 19313
,2007, 'Dynamic modification of a mutant cytoplasmic residue modulates the conductance of the human 5-HT3A receptor', The Journal of Biological Chemistry, 282, pp. 6172 - 6182, http://dx.doi.org/10.1074/jbc.M607698200
,2006, 'Common determinants of single channel conductance within the large cytoplasmic loop of 5-HT3 and á4â2 nicotinic acetylcholine receptors', The Journal of Biological Chemistry, 281, pp. 8062 - 8071, http://dx.doi.org/10.1074/jbc.M513222200
,2006, 'Novel structural determinants of single channel conductance in nicotinic acetylcholine and 5-hydroxytryptamine type-3 receptors', Biochemical Society Transactions, 34, pp. 882 - 886, http://www.biochemsoctrans.org/bst/034/0882/0340882.pdf
,2005, 'Methyllycaconitine analogues have mixed antagonist effects at nicotinic acetylcholine receptors', Bioorganic and Medicinal Chemistry, 13, pp. 4565 - 4575, http://dx.doi.org/10.1016/j.bmc.2005.04.054
,2004, 'Charged residues at the 2 ` position of human GABA(c) rho 1 receptorsinvert ion selectivity and influence open state probability', The Journal of Biological Chemistry, 279, pp. 54153 - 54160
,2004, 'Mutations of the 2' proline in the M2 domain of the human GABAC ĉ1 subunit alter agonist responses', Neuropharmacology, 46, pp. 770 - 781, http://dx.doi.org/10.1016/j.neuropharm.2003.11.027
,Conference Papers
2008, 'External divalent ions increase anion-cation permeability in glycine receptor channels – consideration of ion activities, surface charge and conductance measurements', in Proceedings of the Australian Physiological and Pharmacological Society, presented at Australian Physiological and Pharmacological Society Conference 2008
,Conference Posters
2023, 'A novel practical class using crickets to demonstrate the pharmacological actions of drugs for third year neuropharmacology students', presented at ANS, 04 December 2023 - 07 December 2023
,2023, 'Patient’s experience of a psychiatric, alcohol and non-prescription drug assessment (PANDA) unit', Sydney, presented at ASCEPT, Sydney, 20 November 2023 - 23 November 2023
,2022, 'The trends and opinions of Australian clinicians on the use of antihyperglycemic agents in heart failure patients', Queenstown, New Zealand, presented at ASCEPT-PAGANZ, Queenstown, New Zealand, 25 November 2022 - 29 November 2019
,2021, 'Matters close to the heart: adaptation of a tacrolimus model to inform therapeutic drug monitoring using the PRIOR approach', Virtual, presented at American Conference on Pharmacometrics, Virtual, 08 November 2021 - 12 November 2021
,2021, 'Matters close to the heart: adaptation of a tacrolimus model to inform therapeutic drug monitoring using the PRIOR approach', Virtual, presented at IATDMCT, Virtual, 19 September 2021 - 22 September 2021
,2021, 'Matters close to the heart: adaptation of a tacrolimus model to inform therapeutic drug monitoring using the PRIOR approach', Virtual, presented at Population Approach Group Europe, Virtual, 02 September 2021 - 07 September 2021
,2020, 'Predictive performance of population pharmacokinetic models for tacrolimus in lung transplant recipients', Virtual, presented at ASCEPT, Virtual, 29 November 2020 - 02 December 2020
,2020, 'A step forward in patient safety - understanding barriers to correct intravenous medication administrations', Virtual, presented at ASCEPT, Virtual, 29 November 2020 - 02 December 2020
,2020, 'External evaluation of population pharmacokinetic models of tacrolimus in adult heart transplant recipients', presented at Pharmacometrics Japan, 22 January 2020 - 23 January 2020
,2019, 'Accuracy of documented administration times for intravenous antimicrobial drugs', Queenstown, New Zealand, presented at ASCEPT-PAGANZ, Queenstown, New Zealand, 25 November 2019 - 29 November 2019
,2019, 'Barriers and facilitators to user acceptance of a pilot therapeutic drug monitoring advisory service for vancomycin', Queenstown, New Zealand, presented at ASCEPT-PAGANZ, Queenstown, New Zealand, 25 November 2019 - 29 November 2019
,2019, 'External evaluation of published population pharmacokinetic models of tacrolimus in adult heart transplant recipients', Queenstown, New Zealand, presented at ASCEPT-PAGANZ, Queenstown, New Zealand, 25 November 2019 - 29 November 2019
,2019, 'Population pharmacokinetic models of tacrolimus in adult transplant recipients: a systematic review', Queenstown, New Zealand, presented at ASCEPT-PAGANZ, Queenstown, New Zealand, 25 November 2019 - 29 November 2019
,2019, 'Designing a therapeutic drug monitoring (TDM) advisory service for vancomycin: identifying barriers and facilitators to service implementation', Darwin, Australia, presented at ASID, Darwin, Australia, 16 May 2019 - 18 May 2019
,2019, 'Predictive performance of a commercial Bayesian forecasting program in estimating vancomycin drug exposure', Washington DC, USA, presented at American Society for Clinical Pharmacology and Therapeutics, Washington DC, USA, 14 March 2019 - 16 March 2019
,2018, 'Comparison of vancomycin area-under-the-curve using one and two-compartment pharmacokinetic models', Adelaide, Australia, presented at ASCEPT, Adelaide, Australia, 27 November 2018 - 30 November 2018
,2018, 'Predictive performance of tacrolimus precision dosing software', Adelaide, Australia, presented at ASCEPT, Adelaide, Australia, 27 November 2018 - 30 November 2018
,2018, 'Tacrolimus Dosing and Monitoring in Lung Transplant Patients', Adelaide, Australia, presented at ASCEPT, Adelaide, Australia, 27 November 2018 - 30 November 2018
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