By Associate Professor Shane Thomas

Journal articles

Manandhar B; Pandzic E; Deshpande N; Chen SY; Wasinger VC; Kockx M; Glaros EN; Ong KL; Thomas SR; Wilkins MR; Whan RM; Cochran BJ; Rye KA, 2024, 'ApoA-I Protects Pancreatic β-Cells from Cholesterol-Induced Mitochondrial Damage and Restores Their Ability to Secrete Insulin', Arteriosclerosis, Thrombosis, and Vascular Biology, 44, pp. E20 - E38, http://dx.doi.org/10.1161/ATVBAHA.123.319378

Nguyen TK; Paone S; Baxter AA; Mayfosh AJ; Phan TK; Chan E; Peter K; Poon IKH; Thomas SR; Hulett MD, 2024, 'Heparanase promotes the onset and progression of atherosclerosis in apolipoprotein E gene knockout mice', Atherosclerosis, pp. 117519 - 117519, http://dx.doi.org/10.1016/j.atherosclerosis.2024.117519

Thomas SR; Zhang Y; Rye KA, 2023, 'The pleiotropic effects of high-density lipoproteins and apolipoprotein A-I', Best Practice and Research: Clinical Endocrinology and Metabolism, 37, http://dx.doi.org/10.1016/j.beem.2022.101689

Zhang RYK; Cochran BJ; Thomas SR; Rye KA, 2023, 'Impact of Reperfusion on Temporal Immune Cell Dynamics After Myocardial Infarction', Journal of the American Heart Association, 12, http://dx.doi.org/10.1161/JAHA.122.027600

Zhang Y; Glaros E; Hung T; Zhang R; Rayner BS; Wu B; Ku J; Cochran BJ; Devalaraja M; Thomas S; Rye KA, 2023, 'Abstract 623: A Novel Strategy For Reducing Future Events In Myocardial Infarction Survivors', Arteriosclerosis, Thrombosis, and Vascular Biology, 43, http://dx.doi.org/10.1161/atvb.43.suppl_1.623

Rodrigo C; Herbert C; Saunders D; Thomas S; Polly P, 2022, 'Influence of COVID-19 restrictions on student satisfaction with undergraduate pathology teaching in an Australian University', Frontiers in Education, 7, pp. 1014906, http://dx.doi.org/10.3389/feduc.2022.1014906

Nguyen TK; Paone S; Chan E; Poon IKH; Baxter AA; Thomas SR; Hulett MD, 2022, 'Heparanase: A Novel Therapeutic Target for the Treatment of Atherosclerosis', Cells, 11, http://dx.doi.org/10.3390/cells11203198

Ong KL; Cochran BBiotech BJ; Manandhar B; Thomas S; Rye KA, 2022, 'HDL maturation and remodelling', Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1867, http://dx.doi.org/10.1016/j.bbalip.2022.159119

Guiney L; Glaros E; Vaisar T; Ooi S; Thomas S; Rye K, 2022, 'Longitudinal Analysis of the Effect of an Acute Coronary Syndrome on the Proteome of High-Density Lipoprotein', Heart, Lung and Circulation, 31, pp. S312 - S312, http://dx.doi.org/10.1016/j.hlc.2022.06.542

Parvaneh M; Witting PK; Ku J; Moradi T; Eroglu E; Freedman B; Sutherland GT; McCorkindale A; Guennewig B; Choowong P; Bell-Anderson K; Cooney G; Thomas SR; Eberhard J, 2021, 'Periodontitis induces endothelial dysfunction in mice', Scientific Reports, 11, http://dx.doi.org/10.1038/s41598-021-94418-8

Manandhar B; Pandzic E; Deshpande N; Chen S-Y; Wasinger VC; Kockx M; Glaros E; Ong KL; Thomas S; Wilkins M; Whan R; Cochran BJ; Rye KA, 2021, 'The Anti-Oxidant Function Of Apolipoprotein A-I Rescues Pancreatic beta-Cells From Cholesterol-Induced Mitochondrial Dysfunction', ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 41, http://dx.doi.org/10.1161/atvb.41.suppl_1.122

Maiocchi S; Ku J; Hawtrey T; De Silvestro I; Malle E; Rees M; Thomas SR; Morris JC, 2021, 'Polyamine-Conjugated Nitroxides Are Efficacious Inhibitors of Oxidative Reactions Catalyzed by Endothelial-Localized Myeloperoxidase', Chemical Research in Toxicology, 34, pp. 1681 - 1692, http://dx.doi.org/10.1021/acs.chemrestox.1c00094

Maiocchi SL; Ku J; Thai T; Chan E; Rees MD; Thomas SR, 2021, 'Myeloperoxidase: A versatile mediator of endothelial dysfunction and therapeutic target during cardiovascular disease', Pharmacology and Therapeutics, 221, http://dx.doi.org/10.1016/j.pharmthera.2020.107711

Thai T; Zhong F; Dang L; Chan E; Ku J; Malle E; Geczy CL; Keaney JF; Thomas SR, 2021, 'Endothelial-transcytosed myeloperoxidase activates endothelial nitric oxide synthase via a phospholipase C-dependent calcium signaling pathway', Free Radical Biology and Medicine, 166, pp. 255 - 264, http://dx.doi.org/10.1016/j.freeradbiomed.2020.12.448

Capraro A; Whan R; Thomas S; Jaffe A; Bridge W; Waters S; Hart-Smith G; Zhong L; Pandzic E; Fernando BSM; Awatade N; Wong S, 2020, 'Novel Antioxidant Therapy with the Immediate Precursor to Glutathione, -Glutamylcysteine (GGC), Ameliorates LPS-Induced Cellular Stress in In Vitro 3D-Differentiated Airway Model from Primary Cystic Fibrosis Human Bronchial Cells', Antioxidants, 9, pp. 1 - 19, http://dx.doi.org/10.3390/antiox9121204

El Kazzi M; Rayner BS; Chami B; Dennis JM; Thomas SR; Witting PK, 2020, 'Neutrophil-mediated cardiac damage after acute myocardial infarction: Significance of defining a new target cell type for developing cardioprotective drugs', Antioxidants and Redox Signaling, 33, pp. 689 - 712, http://dx.doi.org/10.1089/ars.2019.7928

Hewson C; Capraro A; Wong S; Pandzic E; Fernando BSM; Awatade N; Zhong L; Hart-Smith G; Whan R; Thomas S; Jaffe A; Bridge W; Waters S, 2020, 'Novel antioxidant therapy with the immediate precursor to glutathione, γ-glutamylcysteine (GGC), ameliorates LPS-induced cellular stress in an in vitro cystic fibrosis model', , http://dx.doi.org/10.1101/2020.05.27.119990

Rodrigo C; Tedla N; Thomas S; Polly P; Herbert C; Velan G; Saunders DN, 2019, 'Using Narratives to Teach Students Enrolled in Science and Medical Science Bachelor’s Degree Programs', Medical Science Educator, 29, pp. 357 - 361, http://dx.doi.org/10.1007/s40670-019-00698-1

Lim YJ; Foo TC; Yeung AWS; Tu X; Ma Y; Hawkins CL; Witting PK; Jameson GNL; Terentis AC; Thomas SR, 2019, 'Human Indoleamine 2,3-Dioxygenase 1 Is an Efficient Mammalian Nitrite Reductase', Biochemistry, 58, pp. 974 - 986, http://dx.doi.org/10.1021/acs.biochem.8b01231

Manuneedhi Cholan P; Cartland SP; Dang L; Rayner BS; Patel S; Thomas SR; Kavurma MM, 2018, 'TRAIL protects against endothelial dysfunction in vivo and inhibits angiotensin-II-induced oxidative stress in vascular endothelial cells in vitro', Free Radical Biology and Medicine, 126, pp. 341 - 349, http://dx.doi.org/10.1016/j.freeradbiomed.2018.08.031

Ramarathinam SH; Gras S; Alcantara S; Yeung AWS; Mifsud NA; Sonza S; Illing PT; Glaros EN; Center RJ; Thomas SR; Kent SJ; Ternette N; Purcell DFJ; Rossjohn J; Purcell AW, 2018, 'Identification of Native and Posttranslationally Modified HLA-B*57:01-Restricted HIV Envelope Derived Epitopes Using Immunoproteomics', Proteomics, 18, http://dx.doi.org/10.1002/pmic.201700253

Manuneedhi Cholan P; Cartland S; Rayner B; Genner S; Dang L; Thomas S; Kavurma M, 2018, 'Abstract 055: TRAIL Protects Against Endothelial Dysfunction in vivo and Inhibits Angiotensin-II Induced Oxidative Stress in Vascular Endothelial Cells in vitro', Arteriosclerosis, Thrombosis, and Vascular Biology, 38, http://dx.doi.org/10.1161/atvb.38.suppl_1.055

Manuneedhi Cholan P; Cartland S; Rayner B; Genner S; Dang L; Thomas S; Kavurma M, 2018, 'Abstract 302: TRAIL Protects Against Endothelial Dysfunction in vivo and Inhibits Angiotensin-II Induced Oxidative Stress in Vascular Endothelial Cells in vitro', Arteriosclerosis, Thrombosis, and Vascular Biology, 38, http://dx.doi.org/10.1161/atvb.38.suppl_1.302

Guiney L; Liou K; Li J; Thomas S; Glaros E; Ooi S, 2018, 'Acute Activation of Polymorphonuclear Granulocyte During Percutaneous Coronary Intervention: Comparison of Myeloperoxidase and Elastase Release and Elimination Kinetics', Heart, Lung and Circulation, 27, pp. S434 - S434, http://dx.doi.org/10.1016/j.hlc.2018.06.882

Liou K; Li J; Guiney L; Thomas S; Glaros E; Ooi S, 2018, 'Coronary Myeloperoxidase Provides Superior Characterisation of Coronary Inflammation in Patients Undergoing Percutaneous Coronary Interventions in the Setting of Non-ST Elevation Acute Coronary Syndrome', Heart, Lung and Circulation, 27, pp. S311 - S311, http://dx.doi.org/10.1016/j.hlc.2018.06.598

Cartland SP; Harith HH; Genner SW; Dang L; Cogger VC; Vellozzi M; Di Bartolo BA; Thomas SR; Adams LA; Kavurma MM, 2017, 'Non-alcoholic fatty liver disease, vascular inflammation and insulin resistance are exacerbated by TRAIL deletion in mice', Scientific Reports, 7, pp. 1898, http://dx.doi.org/10.1038/s41598-017-01721-4

Maiocchi SL; Morris JC; Rees MD; Thomas SR, 2017, 'Regulation of the nitric oxide oxidase activity of myeloperoxidase by pharmacological agents', Biochemical Pharmacology, 135, pp. 90 - 115, http://dx.doi.org/10.1016/j.bcp.2017.03.016

Thomas SR, 2016, 'Haematopoietic-expressed C/EBPβ: A novel transcriptional regulator of hepatic liver metabolism and macrophage foam cells during atherosclerosis?', Atherosclerosis, 250, pp. 183 - 185, http://dx.doi.org/10.1016/j.atherosclerosis.2016.05.015

Huang Y; Thoms JAI; Tursky ML; Knezevic K; Beck D; Chandrakanthan V; Suryani S; Olivier J; Boulton A; Glaros EN; Thomas SR; Lock RB; MacKenzie KL; Bushweller JH; Wong JWH; Pimanda JE, 2016, 'MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation', Leukemia, 30, pp. 1552 - 1561, http://dx.doi.org/10.1038/leu.2016.55

Liou K; Jepson N; Buckley N; Chen V; Thomas S; Russell EA; Ooi SY, 2016, 'Design and Rationale for the Endothelin-1 Receptor Antagonism in the Prevention of Microvascular Injury in Patients with non-ST Elevation Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention (ENDORA-PCI) Trial', Cardiovascular Drugs and Therapy, 30, pp. 169 - 175, http://dx.doi.org/10.1007/s10557-016-6641-x

Tran J; Magenau A; Rodriguez M; Rentero C; Royo T; Enrich C; Thomas SR; Grewal T; Gaus K, 2016, 'Activation of endothelial nitric oxide (eNOS) occurs through different membrane domains in endothelial cells', PLoS ONE, 11, http://dx.doi.org/10.1371/journal.pone.0151556

Thoms JAI; Knezevic K; Liu JJ; Glaros EN; Thai T; Qiao Q; Campbell H; Packham D; Huang Y; Papathanasiou P; Tunningley R; Whittle B; Yeung AWS; Chandrakanthan V; Hesson L; Chen V; Wong JWH; Purton LE; Ward RL; Thomas SR; Pimanda JE, 2016, 'Arrested hematopoiesis and vascular relaxation defects in mice with a mutation in Dhfr', Molecular and Cellular Biology, 36, pp. 1222 - 1236, http://dx.doi.org/10.1128/MCB.01035-15

Harith H; Cartland S; Di Bartolo B; Dang L; Thomas S; Kavurma M, 2016, 'Abstract 614: TRAIL Deletion in Mice Promotes Vascular Insulin Resistance', Arteriosclerosis, Thrombosis, and Vascular Biology, 36, http://dx.doi.org/10.1161/atvb.36.suppl_1.614

Yeung AWS; Lim YJ; Hastad M; Dang L; Örfi L; Szabadkai I; Kéri G; Terentis AC; King NJC; Witting PK; Thomas SR, 2016, 'Redox Control of the Critical Immune Regulatory Enzyme Indoleamine 2,3-Dioxygenase by NADPH Oxidase 2-Derived Reactive Oxygen Species in Human Monocytes', Free Radical Biology and Medicine, 100, pp. S62 - S62, http://dx.doi.org/10.1016/j.freeradbiomed.2016.10.162

Di Bartolo BA; Cartland SP; Prado-Lourenco L; Griffith TS; Gentile C; Ravindran J; Azahri NSM; Thai T; Yeung AWS; Thomas SR; Kavurma MM, 2015, 'Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) promotes angiogenesis and ischemia-induced neovascularization via NADPH oxidase 4 (NOX4) and nitric oxide-dependent mechanisms', Journal of the American Heart Association, 4, http://dx.doi.org/10.1161/JAHA.115.002527

Nasrallah R; Knezevic K; Thai T; Thomas SR; Göttgens B; Lacaud G; Kouskoff V; Pimanda JE, 2015, 'Endoglin potentiates nitric oxide synthesis to enhance definitive hematopoiesis', Biology Open, 4, pp. 819 - 829, http://dx.doi.org/10.1242/bio.011494

Rees MD; Thomas SR, 2015, 'Using cell-substrate impedance and live cell imaging to measure real-time changes in cellular adhesion and de-adhesion induced by matrix modification', Journal of Visualized Experiments, http://dx.doi.org/10.3791/52423

Das T; Kutty SK; Tavallaie R; Ibugo AI; Panchompoo J; Sehar S; Aldous L; Yeung AWS; Thomas SR; Kumar N; Gooding JJ; Manefield M; Amaye I, 2015, 'Phenazine virulence factor binding to extracellular DNA is important for Pseudomonas aeruginosa biofilm formation', Scientific Reports, 5, pp. 8398, http://dx.doi.org/10.1038/srep08398

Yeung AWS; Terentis AC; King NJC; Thomas SR, 2015, 'Role of indoleamine 2,3-dioxygenase in health and disease', Clinical Science, 129, pp. 601 - 672, http://dx.doi.org/10.1042/CS20140392

Rees MD; Thomas SR, 2015, 'Using cell-substrate impedance and live cell imaging to measure real-time changes in cellular adhesion and de-adhesion induced by matrix modification', Journal of visualized experiments : JoVE, http://dx.doi.org/10.3791/52423

Sherrah AG; Edelman JJB; Thomas SR; Brady PW; Wilson MK; Jeremy RW; Bannon PG; Vallely MP, 2014, 'The freestyle aortic bioprosthesis: A systematic review', Heart Lung and Circulation, 23, pp. 1110 - 1117, http://dx.doi.org/10.1016/j.hlc.2014.04.262

Di Bartolo BA; Cartland SP; Prado-Lourenco L; Azahri NSM; Thai T; Yeung A; Thomas SR; Kavurma MM, 2014, 'Abstract 18060: TRAIL Promotes Angiogenesis and Ischemia-Induced Neovascularisation via NOX4, H2O2 and Nitric Oxide-Dependent Mechanisms', Circulation, 130, http://dx.doi.org/10.1161/circ.130.suppl_2.18060

Maiocchi SL; Thomas SR; Rees MD, 2014, 'Regulation of the NO Oxidase Activity of Myeloperoxidase by Pharmacological Agents', FREE RADICAL BIOLOGY AND MEDICINE, 76, pp. S17 - S17, http://dx.doi.org/10.1016/j.freeradbiomed.2014.10.497

Cochran BJ; Bisoendial RJ; Hou L; Glaros E; Rossy J; Thomas SR; Barter PJ; Rye KA, 2014, 'Apolipoprotein a-I increases insulin secretion and production from pancreatic β-cells via a g-protein-camp-PKA-FOXO1-dependent mechanism', Arteriosclerosis, Thrombosis, and Vascular Biology, http://dx.doi.org/10.1161/ATVBAHA.114.304131

Stapelberg M; Zobalova R; Nguyen MN; Walker T; Stantic M; Goodwin J; Pasdar EA; Thai T; Prokopova K; Yan B; Hall S; De Pennington N; Thomas SR; Grant G; Stursa J; Bajzikova M; Meedeniya ACB; Truksa J; Ralph SJ; Ansorge O; Dong LF; Neuzil J, 2014, 'Indoleamine-2,3-dioxygenase elevated in tumor-initiating cells is suppressed by mitocans', Free Radical Biology and Medicine, 67, pp. 41 - 50, http://dx.doi.org/10.1016/j.freeradbiomed.2013.10.003

Rees MD; Maiocchi SL; Kettle AJ; Thomas SR, 2014, 'Mechanism and regulation of peroxidase-catalyzed nitric oxide consumption in physiological fluids: Critical protective actions of ascorbate and thiocyanate', Free Radical Biology and Medicine, 72, pp. 91 - 103, http://dx.doi.org/10.1016/j.freeradbiomed.2014.03.037

Rivera J; Walduck AK; Thomas SR; Glaros EN; Hooker EU; Guida E; Sobey CG; Drummond GR, 2013, 'Accumulation of serum lipids by vascular smooth muscle cells involves a macropinocytosis-like uptake pathway and is associated with the downregulation of the ATP-binding cassette transporter A1', Naunyn-Schmiedeberg's Archives of Pharmacology, 386, pp. 1081 - 1093, http://dx.doi.org/10.1007/s00210-013-0909-5

Sherrah AG; Edelman JJB; Thomas SR; Brady PW; Wilson MK; Jeremy RW; Bannon PG; Vallely MP, 2013, 'The Freestyle Aortic Bioprosthesis: A Systematic Review', Heart Lung and Circulation, http://dx.doi.org/10.1016/j.hlc.2014.04.262

Freewan M; Rees MD; Sempertegui plaza T; Glaros EN; Lim YJ; Wang X; Yeung AWS; Witting PK; Terentis AC; Thomas SR, 2013, 'Human Indoleamine 2,3-dioxygenase is a catalyst of physiological heme peroxidase reactions: implications for the inhibition of dioxygenase activity by hydrogen peroxide', The Journal of Biological Chemistry, 288, pp. 1548 - 1567, http://dx.doi.org/10.1074/jbc.M112.410993

Yeung AWC; Wu W; Freewan M; Stocker R; King NJC; Thomas SR, 2012, 'Flavivirus infection induces indoleamine 2,3-dioxygenase in human monocyte-derived macrophages via tumor necrosis factor and NF-êB', Journal of Leukocyte Biology, 91, pp. 657 - 666, http://dx.doi.org/10.1189/jlb.1011532

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