By Associate Professor Stuart Grant Turville

Preprints

Perkins GB; Hope CM; Chai CS; Tunbridge MJ; Sterling S; Webb K; Yap J; Yeow AEL; Masavuli MG; Kireta S; Zuiani JD; Akerman A; Aggarwal A; Milogiannakis V; Roberts MB; Wilson W; Hurtado PR; Turville S; Grubor-Bauk B; Barry SC; Coates PT; Ravindran J; Hissaria P, 2023, Immune profiling of COVID-19 vaccine responses in people with multiple sclerosis on B cell-depleting therapy, , http://dx.doi.org/10.1101/2023.12.04.23299409

Foster CSP; Walker GJ; Jean T; Wong M; Brassil L; Isaacs S; Lyu Y; Turville S; Kelleher A; Rawlinson WD, 2023, Long-term serial passaging of SARS-CoV-2 reveals signatures of convergent evolution, , http://dx.doi.org/10.1101/2023.11.02.565396

Aggarwal A; Fichter C; Milogiannakis V; Akerman A; Ison T; Ruiz Silva M; Esneau C; Bartlett N; Burrell L; Patel S; Churchill M; Angelovich T; Parry R; Sng JD; Neely GG; Moreno CL; Loo L; Kelleher AD; Brilot F; Khromykh A; Turville SG, 2023, TMPRSS2 activation of Omicron lineage Spike glycoproteins is regulated by TMPRSS2 cleavage of ACE2, , http://dx.doi.org/10.1101/2023.09.22.558930

Perkins GB; Tunbridge MJ; Chai CS; Hope CM; Yeow AEL; Salehi T; Singer J; Shi B; Masavuli MG; Mekonnen ZA; Garcia-Valtanen P; Kireta S; Johnston JK; Drogemuller CJ; Sim BZ; Spencer SM; Sallustio BC; Comerford I; Bouras G; Weiskopf D; Sette A; Aggarwal A; Milogiannakis V; Akerman A; Turville S; Hurtado PR; Ying T; Hissaria P; Barry SC; Chadban SJ; Grubor-Bauk B; Coates PT, 2023, mTOR inhibition improves the formation of functional T cell memory following COVID-19 vaccination of kidney transplant recipients, , http://dx.doi.org/10.1101/2023.03.27.23287773

Lee WS; Tan H-X; Reynaldi A; Esterbauer R; Koutsakos M; Nguyen J; Amarasena T; Kent H; Aggarwal A; Turville S; Taiaroa G; Kinsella P; Liew KC; Tran T; Williamson D; Cromer D; Davenport M; Kent S; Juno J; Khoury D; Wheatley A, 2023, Durable reprogramming of neutralising antibody responses following breakthrough Omicron infection, , http://dx.doi.org/10.1101/2023.02.19.23286159

Phetsouphanh C; Jacka B; Ballouz S; Jackson KJL; Wilson D; Manandhar B; Klemm V; Tan H-X; Wheatley A; Aggarwal A; Akerman A; Milogiannakis V; Starr M; Cunningham P; Turville S; Kent S; Byrne A; Brew B; Darley D; Dore G; Kelleher A; Matthews G, 2023, Improvement of immune dysregulation and health-related quality of life in individuals with long COVID at 24-months following SARS-CoV-2 infection, , http://dx.doi.org/10.1101/2023.08.27.23294704

Moreno C; Castanheira F; Stella AO; Chung F; Aggarwal A; Cole A; Loo L; Dupuy A; Kong Y; Hagimola L; Fenwick J; Coleman P; Willson M; Bui-Marinos M; Hesselson D; Gamble J; Passam F; Turville S; Kubes P; Neely G, 2023, P-Selectin promotes SARS-CoV-2 interactions with platelets and the endothelium, , http://dx.doi.org/10.1101/2023.02.13.528235

Akerman A; Milogiannakis V; Jean T; Esneau C; Silva MR; Ison T; Fitcher C; Lopez JA; Chandra D; Naing Z; Caguicla J; Li D; Walker G; Amatayakul-Chantler S; Roth N; Manni S; Hauser T; Barnes T; Condylios A; Yeang M; Wong M; Foster CSP; Sato K; Lee S; Song Y; Mao L; Sigmund A; Phu A; Vande More AM; Hunt S; Douglas M; Caterson I; Sandgren K; Bull R; Lloyd A; Triccas J; Tangye S; Bartlett NW; Darley D; Matthews G; Stark DJ; Rawlinson WD; Murrell B; Brilot F; Cunningham AL; Kelleher AD; Aggarwal A; Turville SG, 2022, Emergence and antibody evasion of BQ, BA.2.75 and SARS-CoV-2 recombinant sublineages in the face of maturing antibody breadth at the population level, , http://dx.doi.org/10.1101/2022.12.06.22283000

Pillay A; Yeola A; Tea F; Denkova M; Houston S; Burrell R; Merheb V; Lee FXZ; Moran L; Jadhav A; Sterling K; Lai CL; Vitagliano TL; Aggarwal A; Catchpoole D; Wood N; Phan TG; Nanan R; Hsu P; Turville SG; Britton PN; Brilot F, 2022, Infection and vaccine induced Spike antibody responses against SARS-CoV-2 Variants of concern in immune naïve children and adults, , http://dx.doi.org/10.21203/rs.3.rs-2262275/v1

Thijssen V; Hurdiss DL; Debski-Antoniak OJ; Spence MA; Franck C; Norman A; Aggarwal A; Mokiem NJ; van Dongen DAA; Vermeir SW; Liu M; Li W; Chatziandreou M; Donselaar T; Du W; Drulyte I; Bosch B-J; Snijder J; Turville S; Payne RJ; Jackson CJ; van Kuppeveld FJM; Jongkees SAK, 2022, A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein, , http://dx.doi.org/10.1101/2022.11.11.516114

Poumbourios P; Langer C; Boo I; Zakir T; Center RJ; Akerman A; Milogiannakis V; Aggarwal A; Turville S; Drummer. HE, 2022, Enhanced stability of the SARS CoV-2 spike glycoprotein trimer following modification of an alanine cavity in the protein core, , http://dx.doi.org/10.1101/2022.11.08.515567

Faysal KMR; Walsh JC; Renner N; Marquez CL; Shah V; Tuckwell AJ; Christie MP; Parker MW; Turville SG; James L; Towers GJ; Jacques DA; Boecking T, 2022, Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure, , http://dx.doi.org/10.1101/2022.09.21.508807

Aggarwal A; Stella A; Akerman A; Walker G; Milogiannakis V; McAllery S; Esneau C; Silva MR; Lu Y; Forster C; Hal SV; Mathivanan V; Fitcher C; Hoppe AC; Munier ML; Darley D; Matthews G; Starck D; Robosa R; Bartlett N; Rawlinson W; Kelleher A; Turville S, 2022, Rapid isolation and resolution immune evasion and viral fitness across contemporary SARS-CoV-2 variants, , http://dx.doi.org/10.21203/rs.3.rs-1210846/v1

Loo L; Waller M; Cole A; Stella A; Moreno C; Denes C; Hamoudi Z; Chung F; Aggarwal A; Low J; Patel K; Siddiquee R; Mackay J; Turville S; Hesselson D; Neely G, 2022, LRRC15 suppresses SARS-CoV-2 infection and controls collagen production, , http://dx.doi.org/10.21203/rs.3.rs-1172665/v1

Ashhurst A; Johansen M; Maxwell J; Ashley C; Aggarwal A; Siddiquee R; Miemczyk S; Nguyen D; Mackay J; Counoupas C; Byrne S; Turville S; Steain M; Triccas J; Hansbro P; Payne R; Britton W, 2022, Mucosal TLR2-activating protein-based vaccination induces potent pulmonary immunity and protection against SARS-CoV-2 in mice, , http://dx.doi.org/10.21203/rs.3.rs-1179181/v1

Rouet R; Henry J; Johansen M; Sobti M; Balachandran H; Langley D; Walker G; Lenthall H; Jackson J; Ubiparipovic S; Mazigi O; Schofield P; Burnett D; Brown S; Martinello M; Hudson B; Gilroy N; Post J; Kelleher A; Jäck H-M; Goodnow C; Turville S; Rawlinson W; Bull R; Stewart A; Hansbro P; Christ D, 2022, Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients, , http://dx.doi.org/10.1101/2022.10.19.512954

Phetsouphanh C; Khoo WH; Jackson K; Klemm V; Howe A; Aggarwal A; Akerman A; Milogiannakis V; Stella AO; Rouet R; Schofield P; Faulks M; Law H; Danwilai T; Starr M; Munier ML; Christ D; Singh M; Croucher P; Brilot-Turville F; Turville S; Phan TG; Dore G; Darley D; Cunningham P; Matthews G; Kelleher A; Zaunders J, 2022, High titre neutralizing antibodies in response to SARS-CoV-2 infection require RBD-specific CD4 T cells that include proliferative memory cells, , http://dx.doi.org/10.1101/2022.07.22.22277947

Aggarwal A; Akerman A; Milogiannakis V; Silva MR; Walker G; Kidinger A; Angelovich T; Waring E; Amatayakul-Chantler S; Roth N; Coppola G; Yeang M; Jean T; Foster C; Hoppe AC; Ling Munier M; Darley D; Churchill M; Starck D; Christ D; Matthews G; Rawlinson W; Kelleher A; Turville S, 2022, SARS-CoV-2 Omicron BA.5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern, , http://dx.doi.org/10.1101/2022.07.07.22277128

Shen Y; Freeman JA; Holland J; Solterbeck A; Naidu K; Soosapilla A; Downe P; Tang C; Kerridge I; Wallman L; Van Bilsen N; Milogiannakis V; Akerman A; Martins Costa Gomes G; Sandgren K; Cunningham AL; Turville S; Mulligan SP, 2021, COVID-19 Vaccine Failure in Chronic Lymphocytic Leukemia and Monoclonal B-Lymphocytosis; Humoral and Cellular Immunity, , http://dx.doi.org/10.1101/2021.10.28.21265549

Li L; Honda-Okubo Y; Huang Y; Jang H; Carlock MA; Baldwin J; Piplani S; Bebin-Blackwell AG; Forgacs D; Sakamoto K; Stella A; Turville S; Chataway T; Colella A; Triccas J; Ross TM; Petrovsky N, 2021, Immunisation of ferrets and mice with recombinant SARS-CoV-2 spike protein formulated with Advax-SM adjuvant protects against COVID-19 infection, , http://dx.doi.org/10.1101/2021.07.03.451026

Garcia-Valtanen P; Hope C; Masavuli M; Lip Yeow AE; Balachandran H; Mekonnen Z; Al-Delfi Z; Abayasingam A; Agapiou D; Stella AO; Aggarwal A; Gummow J; Ferguson C; O’Connor S; McCartney E; Lynn D; Maddern G; Gowans E; Reddi BAJ; Shaw D; Kok-Lim C; Turville S; Beard M; Weiskopf D; Sette A; Bull R; Barry S; Grubor-Bauk B, 2021, COVID-19 convalescents exhibit deficient humoral and T cell responses to variant of concern Spike antigens at 12 month post-infection, , http://dx.doi.org/10.1101/2021.11.08.21266035

Johansen-Leete J; Ullrich S; Fry S; Frkic R; Bedding M; Aggarwal A; Ashhurst A; Ekanayake K; Mahawaththa M; Sasi V; Passioura T; Larance M; Otting G; Turville S; Jackson C; Nitsche C; Payne R, 2021, Discovery of Antiviral Cyclic Peptides Targeting the Main Protease of SARS-CoV-2 via mRNA Display, , http://dx.doi.org/10.1101/2021.08.23.457419

Loo L; Waller M; Moreno C; Cole A; Stella AO; Pop O-T; Jochum A-K; Ali OH; Denes C; Denes C; Hamoudi Z; Chung F; Aggarwal A; Low J; Patel K; Siddiquee R; Kang T; Mathivanan S; Mackay J; Flatz L; Hesselson D; Turville S; Neely G, 2021, Fibroblast-expressed LRRC15 suppresses SARS-CoV-2 infection and controls antiviral and antifibrotic transcriptional programs, , http://dx.doi.org/10.1101/2021.11.09.467981

Counoupas C; Pino P; Stella A; Ashley C; Lukeman H; Bhattacharyya N; Tada T; Anchisi S; Metayer C; Martinis J; Aggarwal A; Dcosta B; Kint J; Wurm M; Landau N; Steain M; Turville S; Wurm F; David S; Triccas J, 2021, Neutralising antibodies against the SARS-CoV-2 Delta variant induced by Alhydroxyquim-II-adjuvanted trimeric spike antigens, , http://dx.doi.org/10.1101/2021.08.18.456891

Aggarwal A; Stella AO; Walker G; Akerman A; Milogiannakis V; Brilot F; Amatayakul-Chantler S; Roth N; Coppola G; Schofield P; Jackson J; Henry J; Mazigi O; Langley D; Lu Y; Forster C; McAllery S; Mathivanan V; Fichter C; Hoppe AC; Munier ML; Jack H-M; Cromer D; Darley D; Matthews G; Christ D; Khoury D; Davenport M; Rawlinson W; Kelleher A; Turville S, 2021, SARS-CoV-2 Omicron: evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern, , http://dx.doi.org/10.1101/2021.12.14.21267772

Ashhurst AS; Tang AH; Fajtová P; Yoon M; Aggarwal A; Stoye A; Larance M; Beretta L; Drelich A; Skinner D; Li L; Meek TD; McKerrow JH; Hook V; Tseng C-TK; Turville S; Gerwick WH; O'Donoghue AJ; Payne RJ, 2020, Potent in vitro anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L., , http://dx.doi.org/10.1101/2020.12.23.424111

Bull R; Abayasingam A; Balachandran H; Agapiou D; Rodrigo C; Keoshkerian E; Li H; Brasher N; Christ D; Rouet R; Burnett D; Grubor-Bauk B; Rawlinson W; Turville S; Aggarwal A; Brilot F; Mina M; Post J; Hudson B; Gilroy N; Dwyer D; Sasson S; Tea F; Pilli D; Tedla N; Lloyd A; Martinello M, 2020, Long-term persistence of neutralizing memory B cells in SARS-CoV-2, , http://dx.doi.org/10.21203/rs.3.rs-92527/v1

Counoupas C; Johansen M; Stella A; Nguyen D; Ferguson A; Aggarwal A; Bhattacharyya N; Grey A; Patel K; Siddiquee R; Stewart E; Feng C; Hansbro N; Palendira U; Steain M; Saunders B; Low J; Mackay J; Kelleher A; Britton W; Turville S; Hansbro P; Triccas J, 2020, A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilizing immunity against SARS-CoV-2 infection in mice, , http://dx.doi.org/10.1101/2020.12.10.419044

Norman A; Franck C; Christie M; Hawkins P; Patel K; Ashhurst A; Aggarwal A; Low J; Siddiquee R; Ashley C; Steain M; Triccas J; Turville S; Mackay J; Passioura T; Payne R, 2020, Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein using mRNA Display, , http://dx.doi.org/10.1101/2020.12.22.424069

Lau D; Walsh J; Dickson C; Tuckwell A; Stear J; Hunter D; Bhumkar A; Shah V; Turville S; Sierecki E; Gambin Y; Böcking T; Jacques D, 2020, Rapid HIV-1 capsid interaction screening using fluorescence fluctuation spectroscopy, , http://dx.doi.org/10.1101/2020.11.13.382242

Wong AKH; Mathivanan V; Di Giallonardo F; Ahlenstiel C; Turville SG, A Molecular Basis for the Increased Transmission of Ebolavirus in Recent Outbreaks, , http://dx.doi.org/10.2139/ssrn.3507710

Akerman A; Milogiannakis V; Jean T; Esneu C; Silva MR; Ison T; Fitcher C; Lopez JA; Chandra D; Naing Z; Caguicla J; Li D; Walker G; Amatayakul-Chantler S; Roth N; Manni S; Hauser T; Barnes T; Condylios A; Yeang M; Wong M; Foster C; Lee S; Song Y; Mao L; Sigmund A; Phu A; Vande More AM; Hunt S; Douglas M; Caterson I; Sandgren KJ; Bull RA; Lloyd AR; Triccas J; Tangye SG; Bartlett NW; Darley DR; Matthews G; Starck D; Rawlinson W; Brilot F; Cunningham AL; Kelleher A; Aggarwal A; Turville S, Emergence and Antibody Evasion of BQ and BA.2.75 SARS-CoV-2 Sublineages in the Face of Maturing Antibody Breadth at the Population Level, , http://dx.doi.org/10.2139/ssrn.4295993

Abayasingam A; Balachandran H; Agapiou D; Rodrigo C; Keoshkerian E; Li H; Brasher N; Christ D; Rouet R; Burnett D; Grubor-Bauk B; Rawlinson W; Turville S; Aggarwal A; Brilot F; Mina M; Post JJ; Hudson B; Gilroy N; Dwyer D; Sasson S; Tea F; Pilli D; Tedla N; Lloyd AR; Martinello M; Bull RA; Group COSINS, Long-Term Persistence of Neutralizing Memory B Cells in SARS-CoV-2, , http://dx.doi.org/10.2139/ssrn.3732365

Balachandran H; Phetsouphanh C; Agapiou D; Adhikari A; Rodrigo C; Hammoud M; Shrestha LB; Keoshkerian E; Gupta M; Turville S; Christ D; King C; Sasson S; Bartlett A; Grubor-Bauk B; Rawlinson W; Aggarwal A; Stella AO; Klemm V; Mina MM; Post JJ; Hudson B; Gilroy N; Konecny P; Ahlenstiel G; Dwyer D; Sorrell TC; Kelleher A; Tedla N; Lloyd AR; Martinello M; Bull RA, Maintenance of Broad Neutralising Antibodies and Memory B Cells 12 Months Post-Infection Is Predicted by SARS-CoV-2 Specific CD4+ T Cell Responses, , http://dx.doi.org/10.2139/ssrn.3920641

Aggarwal A; Akerman A; Milogiannakis V; Silva MR; Walker G; Kidinger A; Angelovich T; Waring E; Amatayakul-Chantler S; Roth N; Yeang M; Jean T; Foster C; Hoppe AC; Munier ML; Darley DR; Churchill M; Starck D; Christ D; Matthews G; Rawlinson W; Kelleher A; Turville S, SARS-CoV-2 Omicron BA.5: Evolving Tropism and Evasion of Potent Humoral Responses and Resistance to Clinical Immunotherapeutics Relative to Viral Variants of Concern, , http://dx.doi.org/10.2139/ssrn.4157473

Back to profile page