By Catherine Li

Journal articles

Krinos EL; Fields RJ; DeLuca IM; Foutz MA; Li C; Hargett SR; Beretta M; Zhou M; Shrestha R; Gwinn RK; Byrne FL; Hoehn KL; Santos WL, 2026, 'Structure-activity relationship profiling of N-substituted 8-trifluoromethyl-9H-purin-6-amines as mitochondrial protonophores', European Journal of Medicinal Chemistry, 308, http://dx.doi.org/10.1016/j.ejmech.2026.118694

Quinlan JE; Salamoun JM; Garcia CJ; Hargett S; Beretta M; Shrestha R; Li C; Hoehn KL; Santos WL, 2025, 'Unsymmetric hydroxylamine and hydrazine BAM15 derivatives as potent mitochondrial uncouplers', Bioorganic and Medicinal Chemistry, 118, http://dx.doi.org/10.1016/j.bmc.2024.118045

Ho WHJ; Marinova MB; Listijono DR; Bertoldo MJ; Richani D; Kim LJ; Brown A; Riepsamen AH; Cabot S; Frost ER; Bustamante S; Zhong L; Selesniemi K; Wong D; Madawala R; Marchante M; Goss DM; Li C; Araki T; Livingston DJ; Turner N; Sinclair DA; Walters KA; Homer HA; Gilchrist RB; Wu LE, 2024, 'Fertility protection during chemotherapy treatment by boosting the NAD(P)+ metabolome', EMBO Molecular Medicine, 16, pp. 2583 - 2618, http://dx.doi.org/10.1038/s44321-024-00119-w

Zhou M; Li C; Byrne FL; Vancuylenburg CS; Olzomer EM; Hargreaves A; Wu LE; Shackel NA; Santos WL; Hoehn KL, 2024, 'Beneficial effects of MGL-3196 and BAM15 combination in a mouse model of fatty liver disease', Acta Physiologica, 240, http://dx.doi.org/10.1111/apha.14217

Beretta M; Dai Y; Olzomer EM; Vancuylenburg CS; Santiago-Rivera JA; Philp AM; Hargett SR; Li K; Shah DP; Chen SY; Alexopoulos SJ; Li C; Harris TE; Lee B; Wathier M; Cermak JM; Tucker SP; Turner N; Bayliss DA; Philp A; Byrne FL; Santos WL; Hoehn KL, 2024, 'Liver-Selective Imidazolopyrazine Mitochondrial Uncoupler SHD865 Reverses Adiposity and Glucose Intolerance in Mice', Diabetes, 73, pp. 374 - 384, http://dx.doi.org/10.2337/db23-0233

Chen SY; Telfser AJ; Olzomer EM; Vancuylenberg CS; Zhou M; Beretta M; Li C; Alexopoulos SJ; Turner N; Byrne FL; Santos WL; Hoehn KL, 2024, 'Beneficial effects of simultaneously targeting calorie intake and calorie efficiency in diet-induced obese mice', Clinical Science, 138, pp. 173 - 187, http://dx.doi.org/10.1042/CS20231016

Wu LE; Fiveash CE; Bentley NL; Kang MJ; Govindaraju H; Barbour JA; Wilkins BP; Hancock SE; Madawala R; Das A; Massudi H; Li C; Kim LJ; Wong ASA; Marinova MB; Sultani G; Das A; Youngson NA; Le Couteur DG; Sinclair DA; Turner N, 2023, 'SIRT2 transgenic over-expression does not impact lifespan in mice', Aging Cell, 22, http://dx.doi.org/10.1111/acel.14027

Kim LJ; Chalmers TJ; Madawala R; Smith GC; Li C; Das A; Poon EWK; Wang J; Tucker SP; Sinclair DA; Quek LE; Wu LE, 2023, 'Host–microbiome interactions in nicotinamide mononucleotide (NMN) deamidation', FEBS Letters, 597, pp. 2196 - 2220, http://dx.doi.org/10.1002/1873-3468.14698

Murray JH; Burgio AL; Beretta M; Hargett SR; Harris TE; Olzomer E; Grams RJ; Garcia CJ; Li C; Salamoun JM; Hoehn KL; Santos WL, 2023, 'Oxadiazolopyridine Derivatives as Efficacious Mitochondrial Uncouplers in the Prevention of Diet-Induced Obesity', Journal of Medicinal Chemistry, 66, pp. 3876 - 3895, http://dx.doi.org/10.1021/acs.jmedchem.2c01573

Li C; Wu LE, 2021, 'Risks and rewards of targeting NAD+ homeostasis in the brain', Mechanisms of Ageing and Development, 198, http://dx.doi.org/10.1016/j.mad.2021.111545

Bertoldo MJ; Listijono DR; Ho W-HJ; Riepsamen AH; Goss DM; Richani D; Jin XL; Mahbub S; Campbell JM; Habibalahi A; Loh W-GN; Youngson NA; Maniam J; Wong ASA; Selesniemi K; Bustamante S; Li C; Zhao Y; Marinova MB; Kim L-J; Lau L; Wu RM; Mikolaizak AS; Araki T; Le Couteur DG; Turner N; Morris MJ; Walters KA; Goldys E; O'Neill C; Gilchrist RB; Sinclair DA; Homer HA; Wu LE, 2020, 'NAD⁺ Repletion Rescues Female Fertility during Reproductive Aging', CELL REPORTS, 30, pp. 1670 - +, http://dx.doi.org/10.1016/j.celrep.2020.01.058

Das A; Huang GX; Bonkowski MS; Longchamp A; Li C; Schultz MB; Kim LJ; Osborne B; Joshi S; Lu Y; Treviño-Villarreal JH; Kang MJ; Hung TT; Lee B; Williams EO; Igarashi M; Mitchell JR; Wu LE; Turner N; Arany Z; Guarente L; Sinclair DA, 2019, 'Erratum: Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging (Cell (2018) 173(1) (74–89.e20), (S0092867418301521) (10.1016/j.cell.2018.02.008))', Cell, 176, pp. 944 - 945, http://dx.doi.org/10.1016/j.cell.2019.01.026

Das A; Huang GX; Bonkowski MS; Longchamp A; Li C; Schultz MB; Kim LJ; Osborne B; Joshi S; Lu Y; Treviño-Villarreal JH; Kang MJ; Hung TT; Lee B; Williams EO; Igarashi M; Mitchell JR; Wu LE; Turner N; Arany Z; Guarente L; Sinclair DA, 2018, 'Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging', Cell, 173, pp. 74 - 89.e20, http://dx.doi.org/10.1016/j.cell.2018.02.008

Mohamad M; Mitchell SJ; Wu LE; White MY; Cordwell SJ; Mach J; Solon-Biet SM; Boyer D; Nines D; Das A; Catherine Li SY; Warren A; Hilmer SN; Fraser R; Sinclair DA; Simpson SJ; de Cabo R; Le Couteur DG; Cogger VC, 2016, 'Ultrastructure of the liver microcirculation influences hepatic and systemic insulin activity and provides a mechanism for age-related insulin resistance', Aging Cell, 15, pp. 706 - 715, http://dx.doi.org/10.1111/acel.12481

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