Select Publications
Journal articles
, 2019, 'Efficacy and safety of triple versus dual combination blood pressure-lowering drug therapy: A systematic review and meta-analysis of randomized controlled trials', Journal of Hypertension, 37, pp. 1567 - 1573, http://dx.doi.org/10.1097/HJH.0000000000002089
, 2019, 'Thyroid Nodules in Type 2 Diabetes Mellitus', Current Medical Science, 39, pp. 576 - 581, http://dx.doi.org/10.1007/s11596-019-2076-5
, 2019, 'Determinants of the high admission blood pressure in mild-to-moderate acute intracerebral hemorrhage', Journal of Hypertension, 37, pp. 1463 - 1466, http://dx.doi.org/10.1097/HJH.0000000000002056
, 2019, 'Lowering blood pressure after acute intracerebral haemorrhage: Protocol for a systematic review and meta-analysis using individual patient data from randomised controlled trials participating in the Blood Pressure in Acute Stroke Collaboration (BASC)', BMJ Open, 9, pp. e030121, http://dx.doi.org/10.1136/bmjopen-2019-030121
, 2019, 'Blood pressure variability and outcome in acute ischemic and hemorrhagic stroke: a post hoc analysis of the HeadPoST study', Journal of Human Hypertension, 33, pp. 411 - 418, http://dx.doi.org/10.1038/s41371-019-0193-z
, 2019, 'Effects of continuous positive airway pressure on depression and anxiety symptoms in patients with obstructive sleep apnoea: results from the sleep apnoea cardiovascular Endpoint randomised trial and meta-analysis', Eclinicalmedicine, 11, pp. 89 - 96, http://dx.doi.org/10.1016/j.eclinm.2019.05.012
, 2019, 'Infratentorial Intracerebral Hemorrhage: Relation of Location to Outcome', Stroke, 50, pp. 1257 - 1259, http://dx.doi.org/10.1161/STROKEAHA.118.023766
, 2019, 'Statistical analysis plan for pooled individual patient data from two landmark randomized trials (INTERACT2 and ATACH-II) of intensive blood pressure lowering treatment in acute intracerebral hemorrhage', International Journal of Stroke, 14, pp. 321 - 328, http://dx.doi.org/10.1177/1747493018813695
, 2019, 'Hyperuricemia and its related histopathological features on renal biopsy', BMC Nephrology, 20, pp. 95, http://dx.doi.org/10.1186/s12882-019-1275-4
, 2019, 'Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial', Lancet, 393, pp. 877 - 888, http://dx.doi.org/10.1016/S0140-6736(19)30038-8
, 2019, 'The National Institute for Health Research Hyperacute Stroke Research Centres and the ENCHANTED trial: The impact of enhanced research infrastructure on trial metrics and patient outcomes', Health Research Policy and Systems, 17, pp. 19, http://dx.doi.org/10.1186/s12961-019-0417-2
, 2019, 'Determinants of Early Versus Delayed Neurological Deterioration in Intracerebral Hemorrhage: The INTERACT-2 Study', Stroke, 50, pp. 1409 - 1414, http://dx.doi.org/10.1161/STROKEAHA.118.024403
, 2019, 'Ginkgetin aglycone attenuates neuroinflammation and neuronal injury in the rats with ischemic stroke by modulating STAT3/JAK2/SIRT1', Folia Neuropathologica, 57, pp. 16 - 23, http://dx.doi.org/10.5114/fn.2019.83827
, 2019, 'Abstract TP362: Comparison of the Simplified Modified Rankin Scale Questionnaire With Conventional Neurological Scales in the Dose Arm of the Enchanted Study', Stroke, 50, http://dx.doi.org/10.1161/str.50.suppl_1.tp362
, 2019, 'Abstract TP371: Adopting a Patient-centered Approach in Acute Stroke Trials With Utility-weighted Modified Rankin Scale Scores', Stroke, 50, http://dx.doi.org/10.1161/str.50.suppl_1.tp371
, 2019, 'Abstract WP107: Early Recurrence of Ischemic Stroke in Alteplase-treated Patients: The ENCHANTED Study', Stroke, 50, http://dx.doi.org/10.1161/str.50.suppl_1.wp107
, 2018, 'A Simple Modified Framingham Scoring System to Predict Obstructive Coronary Artery Disease', Journal of Cardiovascular Translational Research, 11, pp. 495 - 502, http://dx.doi.org/10.1007/s12265-018-9837-6
, 2018, 'Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial', Lancet Neurology, 17, pp. 1053 - 1060, http://dx.doi.org/10.1016/S1474-4422(18)30319-3
, 2018, 'Statistical analysis plan for evaluating different intensities of blood pressure control in the ENhanced Control of Hypertension And Thrombolysis strokE stuDy.', International Journal of Stroke, pp. 1 - 4, http://dx.doi.org/10.1177/1747493018806170
, 2018, 'Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data', Lancet Neurology, 17, pp. 885 - 894, http://dx.doi.org/10.1016/S1474-4422(18)30253-9
, 2018, 'High Risk Characteristics for Recurrent Cardiovascular Events among Patients with Obstructive Sleep Apnoea in the SAVE Study', Eclinicalmedicine, 2-3, pp. 59 - 65, http://dx.doi.org/10.1016/j.eclinm.2018.09.002
, 2018, 'Lipid-lowering pretreatment and outcome following intravenous thrombolysis for acute ischaemic stroke: a post hoc analysis of the enhanced control of hypertension and thrombolysis stroke study trial', Cerebrovascular Diseases, 45, pp. 213 - 220, http://dx.doi.org/10.1159/000488911
, 2018, 'SP243PROGNOSTIC SIGNIFICANCE OF LOW LEVEL OF BLOOD GLUCOSE IN SEVERE ACUTE KIDNEY INJURY: A SECONDARY ANALYSIS FROM THE RENAL STUDY', Nephrology Dialysis Transplantation, 33, pp. i425 - i425, http://dx.doi.org/10.1093/ndt/gfy104.sp243
, 2018, 'Comparative effects of low-dose versus standard-dose alteplase in ischemic patients with prior stroke and/or diabetes mellitus: The ENCHANTED trial', Journal of the Neurological Sciences, 387, pp. 1 - 5, http://dx.doi.org/10.1016/j.jns.2018.01.014
, 2018, 'Current status of intravenous tissue plasminogen activator dosage for acute ischaemic stroke: An updated systematic review', Stroke and Vascular Neurology, 3, pp. 28 - 33, http://dx.doi.org/10.1136/svn-2017-000112
, 2018, 'Clinical utility of electronic Alberta stroke program early computed tomography score software in the ENCHANTED trial database', Stroke, 49, pp. 1407 - 1411, http://dx.doi.org/10.1161/STROKEAHA.117.019863
, 2018, 'Low- versus standard-dose intravenous alteplase in the context of bridging therapy for acute ischemic stroke: A Korean ENCHANTED study', Journal of Stroke, 20, pp. 131 - 139, http://dx.doi.org/10.5853/jos.2017.01578
, 2018, 'A12614 Predictors of severity of hypertensive response in acute intracerebral haemorrhage', Journal of Hypertension, 36, pp. e323, http://dx.doi.org/10.1097/01.hjh.0000549321.17364.3c
, 2017, 'Early Cognitive Impairment after Intracerebral Hemorrhage in the INTERACT1 Study', Cerebrovascular Diseases, 44, pp. 320 - 324, http://dx.doi.org/10.1159/000481443
, 2017, 'Practice patterns for neurosurgical utilization and outcome in acute intracerebral hemorrhage: Intensive blood pressure reduction in acute cerebral hemorrhage trials 1 and 2 studies', Clinical Neurosurgery, 81, pp. 980 - 985, http://dx.doi.org/10.1093/neuros/nyx129
, 2017, 'Low-dose vs standard-dose alteplase for patients with acute ischemic stroke: Secondary analysis of the ENCHANTED randomized clinical trial', JAMA Neurology, 74, pp. 1328 - 1335, http://dx.doi.org/10.1001/jamaneurol.2017.2286
, 2017, 'Influence of Renal Impairment on Outcome for Thrombolysis-Treated Acute Ischemic Stroke: ENCHANTED (Enhanced Control of Hypertension and Thrombolysis Stroke Study) Post Hoc Analysis', Stroke, 48, pp. 2605 - 2609, http://dx.doi.org/10.1161/STROKEAHA.117.017808
, 2017, 'Frequency, determinants, and effects of early seizures after thrombolysis for acute ischemic stroke: The ENCHANTED trial', Neurology Clinical Practice, 7, pp. 324 - 332, http://dx.doi.org/10.1212/CPJ.0000000000000384
, 2017, 'Admission Low Magnesium Level Is Associated with In-Hospital Mortality in Acute Ischemic Stroke Patients', Cerebrovascular Diseases, 44, pp. 35 - 42, http://dx.doi.org/10.1159/000471858
, 2017, 'Low-Versus Standard-Dose Alteplase in Patients on Prior Antiplatelet Therapy the ENCHANTED Trial (Enhanced Control of Hypertension and Thrombolysis Stroke Study)', Stroke, 48, pp. 1877 - 1883, http://dx.doi.org/10.1161/STROKEAHA.116.016274
, 2017, 'Characteristics, management and response to alteplase in China versus non-China participants of the ENCHANTED trial', Stroke and Vascular Neurology, 2, pp. 53 - 58, http://dx.doi.org/10.1136/svn-2017-000085
, 2017, 'Intensive Care Unit Admission for Patients in the INTERACT2 ICH Blood Pressure Treatment Trial: Characteristics, Predictors, and Outcomes', Neurocritical Care, 26, pp. 371 - 378, http://dx.doi.org/10.1007/s12028-016-0365-4
, 2017, 'SP311INFLUENCE OF RENAL IMPAIRMENT ON OUTCOME FOR THROMBOLYSIS-TREATED ACUTE ISCHEMIC STROKE: THE ENCHANTED TRIAL', Nephrology Dialysis Transplantation, 32, pp. iii212 - iii212, http://dx.doi.org/10.1093/ndt/gfx146.sp311
, 2017, 'Intracerebral hemorrhage location and outcome among INTERACT2 participants', Neurology, 88, pp. 1408 - 1414, http://dx.doi.org/10.1212/WNL.0000000000003771
, 2017, 'Withdrawal of active treatment after intracerebral haemorrhage in the INTERACT2 study', Age and Ageing, 46, pp. 329 - 332, http://dx.doi.org/10.1093/ageing/afw187
, 2017, 'Prognostic significance of delayed intraventricular haemorrhage in the INTERACT studies', Journal of Neurology Neurosurgery and Psychiatry, 88, pp. 19 - 24, http://dx.doi.org/10.1136/jnnp-2015-311562
, 2017, 'Abstract 148: Evaluation of Sex, Racial and Geographic Demographics and Outcomes in Clinical Trials of Spontaneous Intracerebral Hemorrhage', Stroke, 48, http://dx.doi.org/10.1161/str.48.suppl_1.148
, 2017, 'Abstract TMP25: Effects of Age and Ethnicity on the Benefits and Risks of Low- versus Standard-dose Alteplase in Acute Ischemic Stroke Patients: The Enchanted Trial', Stroke, 48, http://dx.doi.org/10.1161/str.48.suppl_1.tmp25
, 2016, 'Early blood pressure lowering in patients with intracerebral haemorrhage and prior use of antithrombotic agents: Pooled analysis of the INTERACT studies', Journal of Neurology Neurosurgery and Psychiatry, 87, pp. 1330 - 1335, http://dx.doi.org/10.1136/jnnp-2016-313246
, 2016, 'Early Blood Pressure Lowering Does Not Reduce Growth of Intraventricular Hemorrhage following Acute Intracerebral Hemorrhage: Results of the INTERACT Studies', Cerebrovascular Diseases Extra, 6, pp. 71 - 75, http://dx.doi.org/10.1159/000448897
, 2016, 'Ambient temperature and stroke occurrence: A systematic review and meta-analysis', International Journal of Environmental Research and Public Health, 13, pp. 698, http://dx.doi.org/10.3390/ijerph13070698
, 2016, 'Air Pressure, Humidity and Stroke Occurrence: A Systematic Review and Meta-Analysis', International Journal of Environmental Research and Public Health, 13, pp. 675, http://dx.doi.org/10.3390/ijerph13070675
, 2016, 'Estimated GFR and the Effect of Intensive Blood Pressure Lowering after Acute Intracerebral Hemorrhage', American Journal of Kidney Diseases, 68, pp. 94 - 102, http://dx.doi.org/10.1053/j.ajkd.2016.01.020
, 2016, 'Prognostic significance of hyponatremia in acute intracerebral hemorrhage: Pooled analysis of the intensive blood pressure reduction in acute cerebral hemorrhage trial studies', Critical Care Medicine, 44, pp. 1388 - 1394, http://dx.doi.org/10.1097/CCM.0000000000001628
, 2016, 'Prophylactic heparin in acute intracerebral hemorrhage: A propensity score-matched analysis of the INTERACT2 study', International Journal of Stroke, 11, pp. 549 - 556, http://dx.doi.org/10.1177/1747493016641113