By Conjoint Professor Maria Kavallaris

Journal articles

McCarroll JA; Dwarte T; Baigude H; Dang J; Yang L; Erlich RB; Kimpton K; Teo J; Sagnella SM; Akerfeldt MC; Liu J; Phillips PA; Rana TM; Kavallaris M, 2015, 'Therapeutic targeting of polo-like kinase 1 using RNA-interfering nanoparticles (iNOPs) for the treatment of non-small cell lung cancer', Oncotarget, 6, pp. 12020 - 12034, http://dx.doi.org/10.18632/oncotarget.2664

McCarroll JA; Sharbeen G; Liu J; Youkhana J; Goldstein D; McCarthy N; Limbri LF; Dischl D; Ceyhan GO; Erkan M; Johns AL; Biankin AV; Kavallaris M; Phillips PA; Johns A, 2015, 'βIII-Tubulin: A novel mediator of chemoresistance and metastases in pancreatic cancer', Oncotarget, 6, pp. 2235 - 2249, http://dx.doi.org/10.18632/oncotarget.2946

Pasquier E; Tuset MP; Sinnappan S; Carnell M; Macmillan A; Kavallaris M, 2015, 'γ-Actin plays a key role in endothelial cell motility and neovessel maintenance', Vascular Cell, 7, http://dx.doi.org/10.1186/s13221-014-0027-2

Brandl MB; Pasquier E; Li F; Beck D; Zhang S; Zhao H; Kavallaris M; Wong STC, 2014, 'Computational analysis of image-based drug profiling predicts synergistic drug combinations: Applications in triple-negative breast cancer', Molecular Oncology, 8, pp. 1548 - 1560, http://dx.doi.org/10.1016/j.molonc.2014.06.007

Chen X; Soeriyadi AH; Lu X; Sagnella SM; Kavallaris M; Gooding JJ, 2014, 'Dual bioresponsive mesoporous silica nanocarrier as an "AND" logic gate for targeted drug delivery cancer cells', Advanced Functional Materials, 24, pp. 6999 - 7006, http://dx.doi.org/10.1002/adfm.201402339

Eiffe E; Pasquier E; Kavallaris M; Herbert C; Black DSC; Kumar N, 2014, 'Synthesis, anti-cancer and anti-inflammatory activity of novel 2-substituted isoflavenes', Bioorganic and Medicinal Chemistry, 22, pp. 5182 - 5193, http://dx.doi.org/10.1016/j.bmc.2014.08.010

Liu PY; Erriquez D; Marshall GM; Tee AE; Polly P; Wong M; Liu B; Bell JL; Zhang XD; Milazzo G; Cheung BB; Fox A; Swarbrick A; Hüttelmaier S; Kavallaris M; Perini G; Mattick JS; Dinger ME; Liu T, 2014, 'Effects of a Novel Long Noncoding RNA, lncUSMycN, on N-Myc Expression and Neuroblastoma Progression', Journal of the National Cancer Institute, 106, http://dx.doi.org/10.1093/jnci/dju113

Kim PY; Tan O; Diakiw SM; Carter D; Sekerye EO; Wasinger VC; Liu T; Kavallaris M; Norris MD; Haber M; Chesler L; Dolnikov A; Trahair TN; Cheung NK; Marshall GM; Cheung BB, 2014, 'Identification of plasma Complement C3 as a potential biomarker for neuroblastoma using a quantitative proteomic approach', Journal of Proteomics, 96, pp. 1 - 12, http://dx.doi.org/10.1016/j.jprot.2013.10.032

Sagnella SM; Hien D; MacMillan A; Boyer C; Whan R; McCarroll JA; Davis TP; Kavallaris M, 2014, 'Dextran-Based Doxorubicin Nanocarriers with Improved Tumor Penetration', BIOMACROMOLECULES, 15, pp. 262 - 275, http://dx.doi.org/10.1021/bm401526d

Sagnella SM; McCarroll JA; Kavallaris M, 2014, 'Drug delivery: Beyond active tumour targeting', Nanomedicine Nanotechnology Biology and Medicine, 10, pp. 1131 - 1137, http://dx.doi.org/10.1016/j.nano.2014.04.012

Vittorio O; Voliani V; Faraci P; Karmakar B; Iemma F; Hampel S; Kavallaris M; Cirillo G, 2014, 'Magnetic catechin-dextran conjugate as targeted therapeutic for pancreatic tumour cells', Journal of Drug Targeting, 22, pp. 408 - 415, http://dx.doi.org/10.3109/1061186X.2013.878941

Parker AL; Kavallaris M; McCarroll JA, 2014, 'Microtubules and their role in cellular stress in cancer', Frontiers in Oncology, 4 JUN, pp. 153, http://dx.doi.org/10.3389/fonc.2014.00153

Fife CM; McCarroll JA; Kavallaris M, 2014, 'Movers and shakers: Cell cytoskeleton in cancer metastasis', British Journal of Pharmacology, 171, pp. 5507 - 5523, http://dx.doi.org/10.1111/bph.12704

Vittorio O; Brandl M; Cirillo G; Spizzirri UG; Picci N; Kavallaris M; Iemma F; Hampel S, 2014, 'Novel functional cisplatin carrier based on carbon nanotubes-quercetin nanohybrid induces synergistic anticancer activity against neuroblastoma in vitro', Rsc Advances, 4, pp. 31378 - 31384, http://dx.doi.org/10.1039/c4ra03331k

McCarroll JA; Naim S; Sharbeen G; Russia N; Lee J; Kavallaris M; Goldstein D; Phillips PA, 2014, 'Role of pancreatic stellate cells in chemoresistance in pancreatic cancer', Frontiers in Physiology, 5 APR, pp. 141, http://dx.doi.org/10.3389/fphys.2014.00141

Chen X; Cheng X; Soeriyadi AH; Sagnella SM; Lu X; Scott JA; Lowe SB; Kavallaris M; Gooding JJ, 2014, 'Stimuli-responsive functionalized mesoporous silica nanoparticles for drug release in response to various biological stimuli', Biomaterials Science, 2, pp. 121 - 130, http://dx.doi.org/10.1039/c3bm60148j

Sagnella SM; McCarroll JA; Kavallaris M, 2014, 'Drug delivery: Beyond active tumour targeting', Nanomedicine: Nanotechnology, Biology, and Medicine, http://dx.doi.org/10.1016/j.nano.2014.04.012

McCarroll J; Teo J; Boyer C; Goldstein D; Kavallaris M; Phillips PA, 2014, 'Potential applications of nanotechnology for the diagnosis and treatment of pancreatic cancer', Frontiers in Physiology, 5, pp. 1 - 10, http://dx.doi.org/10.3389/fphys.2014.00002

Byrne FL; Yang L; Phillips PA; Hansford LM; Fletcher JI; Ormandy CJ; McCarroll JA; Kavallaris M, 2014, 'RNAi-mediated stathmin suppression reduces lung metastasis in an orthotopic neuroblastoma mouse model', Oncogene, 33, pp. 882 - 890, http://dx.doi.org/10.1038/onc.2013.11

Sevimli S; Sagnella S; Kavallaris M; Bulmus V; Davis TP, 2013, 'Assessment of cholesterol-derived ionic copolymers as potential vectors for gene delivery.', Biomacromolecules, 14, pp. 4135 - 4149, http://dx.doi.org/10.1021/bm4013088

Basuki JS; Duong HTT; Macmillan A; Erlich RB; Esser L; Akerfeldt MC; Whan RM; Kavallaris M; Boyer C; Davis TP, 2013, 'Using Fluorescence Lifetime Imaging Microscopy to Monitor Theranostic Nanoparticle Uptake and Intracellular Doxorubicin Release', ACS NANO, 7, pp. 10175 - 10189, http://dx.doi.org/10.1021/nn404407g

Pasquier E; Trahair T; Kavallaris M; Andre N, 2013, 'Reply: Comment on 'beta-blockers increase response to chemotherapy via direct anti-tumour and anti-angiogenic mechanisms in neuroblastoma'-β- blockers are potent anti-angiogenic and chemo-sensitising agents, rather than cytotoxic drugs', British Journal of Cancer, 109, pp. 2024 - 2025, http://dx.doi.org/10.1038/bjc.2013.498

Pasquier E; Street J; Pouchy C; Carre M; Gifford AJ; Murray J; Norris MD; Trahair T; Andre N; Kavallaris M, 2013, 'B-blockers increase response to chemotherapy via direct antitumour and anti-angiogenic mechanisms in neuroblastoma', British Journal of Cancer, 108, pp. 2485 - 2494, http://dx.doi.org/10.1038/bjc.2013.205

Teo J; Erlich RB; Sagnella S; Dwarte T; Davis TP; Kavallaris M; McCarroll J; Boyer C; Duong HTT; Phillips P; Sharbeen G; Goldstein D, 2013, 'Effective delivery of siRNA into cancer cells and tumors using well-defined biodegradable cationic star polymers', Molecular Pharmaceutics, 10, pp. 2435 - 2444, http://dx.doi.org/10.1021/mp400049e

Bell JL; Malyukova A; Kavallaris M; Marshall GM; Cheung BB, 2013, 'TRIM16 inhibits neuroblastoma cell proliferation through cell cycle regulation and dynamic nuclear localization.', Cell Cycle, 12, pp. 889 - 898, http://dx.doi.org/10.4161/cc.23825

Po'uha ST; Honore S; Braguer D; Kavallaris M, 2013, 'Partial depletion of gamma-actin suppresses microtubule dynamics', Cytoskeleton, 70, pp. 148 - 160, http://dx.doi.org/10.1002/cm.21096

Pasquier E; Tuset MP; Street J; Sinnappan SM; Mackenzie KL; Braguer D; Andre N; Kavallaris M, 2013, 'Concentration- and schedule-dependent effects of chemotherapy on the angiogenic potential and drug sensitivity of vascular endothelial cells', Angiogenesis, 16, pp. 373 - 386, http://dx.doi.org/10.1007/s10456-012-9321-x

Duong HTT; Kamarudin ZM; Erlich RB; Li Y; Jones MJ; Kavallaris M; Boyer CA; Davis TP, 2013, 'Intracellular nitric oxide delivery from stable NO-polymeric nanoparticle carriers', Chemical Communications, 49, pp. 4190 - 4192, http://dx.doi.org/10.1039/c2cc37181b

Duong HTT; Hughes F; Sagnella S; Kavallaris M; MacMillan A; Whan R; Hook J; Davis TP; Boyer C, 2012, 'Functionalizing biodegradable dextran scaffolds using living radical polymerization: New versatile nanoparticles for the delivery of therapeutic molecules', Molecular Pharmaceutics, 9, pp. 3046 - 3061, http://dx.doi.org/10.1021/mp300144y

Mccarroll JA; Baigude H; Erlich R; Dwarte T; Rana TM; Kayallaris M, 2012, 'Silencing alll-tubulin by RNA interfering nanoparticles in non-small cell lung cancer', CANCER RESEARCH, 72, http://dx.doi.org/10.1158/1538-7445.AM2012-1969

Kan C; Wen VW; Pasquier E; Jankowski K; Chang M; Richards LA; Kavallaris M; Mackenzie K, 2012, 'Endothelial cell dysfunction and cytoskeletal changes associated with repression of p16(INK4a) during immortalization', Oncogene, 31, pp. 4815 - 4827, http://dx.doi.org/10.1038/onc.2011.645

Failes TW; Mitic G; Abdel-halim H; Po'uha ST; Liu M; Hibbs DE; Kavallaris M, 2012, 'Evolution of Resistance to Aurora Kinase B Inhibitors in Leukaemia Cells', PLoS ONE, 7, pp. e30734, http://dx.doi.org/10.1371/journal.pone.0030734

Sevimli S; Sagnella SM; Kavallaris M; Bulmus V; Davis TP, 2012, 'Synthesis, self-assembly and stimuli responsive properties of cholesterol conjugated polymers', Polymer Chemistry, 3, pp. 2057 - 2069, http://dx.doi.org/10.1039/c2py20112g

Cheung BB; Koach J; Tan O; Kim P; Bell JL; D'andreti C; Sutton S; Malyukova A; Sekyere E; Norris M; Haber M; Kavallaris M; Cunningham AM; Proby C; Leigh I; Wilmott JS; Cooper CL; Halliday GM; Scolyer RA; Marshall GM, 2012, 'The retinoid signalling molecule, TRIM16, is repressed during squamous cell carcinoma skin carcinogenesis in vivo and reduces skin cancer cell migration in vitro.', J Pathol, 226, pp. 451 - 462, http://dx.doi.org/10.1002/path.2986

Bell JL; Malyukova A; Holien JK; Koach J; Parker MW; Kavallaris M; Marshall GM; Cheung BB, 2012, 'TRIM16 acts as an E3 ubiquitin ligase and can heterodimerize with other TRIM family members.', PLoS One, 7, pp. e37470, http://dx.doi.org/10.1371/journal.pone.0037470

Schofield DJ; Meachem S; West C; Kavallaris M; Callander EJ, 2011, 'A crisis in the making? Education, ageing populations and the future of the medical research workforce', Medical Education, 45, pp. 200 - 207, http://dx.doi.org/10.1111/j.1365-2923.2010.03785.x

Ginu A; McCarroll J; Byrne F; Saricilar S; Kavallaris M; Bulmus V, 2011, 'Block Co-polymer Nanoparticles with Degradable Cross-Linked Core and Low-Molecular-Weight PEG Corona for Anti-tumour Drug Delivery', Journal of Biomaterials Science - Polymer Edition, 22, pp. 1001 - 1022, http://dx.doi.org/10.1163/092050610X497872

Kow SC; McCarroll J; Valade D; Boyer CA; Dwarte T; Davis TP; Kavallaris M; Bulmus V, 2011, 'Dicer-Labile PEG Conjugates for siRNA Delivery', Biomacromolecules, 12, pp. 4301 - 4310, http://dx.doi.org/10.1021/bm201199c

Wong L; Kavallaris M; Bulmus V, 2011, 'Doxorubicin conjugated, crosslinked, PEGylated particles prepared via one-pot thiol-ene modification of a homopolymer scaffold: synthesis and in vitro evaluation', Polymer Chemistry, 2, pp. 385 - 393, http://dx.doi.org/10.1039/c0py00256a

Nakano M; Saldanha R; Gobel A; Kavallaris M; Packer NH, 2011, 'Identification of Glycan Structure Alterations on Cell Membrane Proteins in Desoxyepothilone B Resistant Leukemia Cells', Molecular and Cellular Proteomics, 10, http://dx.doi.org/10.1074/mcp.M111.009001

Pasquier E; Ciccolini J; Carre M; Giacometti S; Fanciullino R; Pouchy C; Montero MP; Serdjebi C; Kavallaris M; Andre N, 2011, 'Propranolol potentiates the anti-angiogenic effects and anti-tumor efficacy of chemotherapy agents: implication in breast cancer treatment.', Oncotarget, 2, pp. 797 - 809

Gan PP; Mccarroll J; Byrne F; Garner J; Kavallaris M; Byrne F, 2011, 'Specific beta-Tubulin Isotypes Can Functionally Enhance or Diminish Epothilone B Sensitivity in Non-Small Cell Lung Cancer Cells', PLoS One, 6, pp. e21717, http://dx.doi.org/10.1371/journal.pone.0021717

Katsetos CD; Draber P; Kavallaris M, 2011, 'Targeting betaIII-tubulin in glioblastoma multiforme: From cell biology and histopathology to cancer therapeutics', Anti-Cancer Agents in Medicinal Chemistry, 11, pp. 719 - 728, http://dx.doi.org/10.2174/187152011797378760

Shum MSY; Pasquier E; Po'uha ST; O'Neill GM; Chaponnier C; Gunning PW; Kavallaris M, 2011, 'γ-Actin regulates cell migration and modulates the ROCK signaling pathway', FASEB JOURNAL, 25, pp. 4423 - 4433, http://dx.doi.org/10.1096/fj.11-185447

Marshall GM; Bell JL; Koach J; Tan O; Kim P; Malyukova A; Thomas W; Sekyere EO; Liu T; Cunningham AM; Tobias V; Norris MD; Haber M; Kavallaris M; Cheung BB, 2010, 'TRIM16 acts as a tumour suppressor by inhibitory effects on cytoplasmic vimentin and nuclear E2F1 in neuroblastoma cells.', Oncogene, 29, pp. 6172 - 6183, http://dx.doi.org/10.1038/onc.2010.340

Kavallaris M, 2010, 'Erratum: Microtubules and resistance to tubulin-binding agents (Nature Reviews Cancer)', Nature Reviews Cancer, 10, pp. 309, http://dx.doi.org/10.1038/nrc2819

Kavallaris M, 2010, 'Microtubules and resistance to tubulin-binding agents', Nature Reviews Cancer, http://dx.doi.org/10.1038/nrc2830

Boyer CA; Priyanto P; Davis TP; Pissuwan D; Bulmus V; Kavallaris M; Teoh WY; Amal R; Carroll M; Woodward R; St pierre T, 2010, 'Anti-fouling magnetic nanoparticles for siRNA delivery', Journal of Materials Chemistry, 20, pp. 255 - 265, http://dx.doi.org/10.1039/b914063h

McCarroll J; Gan PP; Liu M; Kavallaris M, 2010, 'beta III-Tubulin Is a Multifunctional Protein Involved in Drug Sensitivity and Tumorigenesis in Non-Small Cell Lung Cancer', Cancer research, 70, pp. 4995 - 5003, http://dx.doi.org/10.1158/0008-5472.CAN-09-4487

Abraham G; McCaroll J; Byrne F; Saricilar S; Kavallaris M; Bulmus V, 2010, 'Block Co-polymer Nanoparticles with Degradable Cross-Linked Core and Low-Molecular-Weight PEG Corona for Anti-tumour Drug Delivery', Journal of Biomaterials Science - Polymer Edition, 22, pp. 1001 - 1022, http://dx.doi.org/10.1163/092050610X497872

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