By Conjoint Professor Maria Kavallaris

Journal articles

Sharbeen G; Kokkinos J; Schulstad G; Pandzic E; Youkhana J; Ma Z; Ignacio RMC; Raina AS; Chiang S; Boyer C; Haghighi KS; Gunawarman M; Goldstein D; Gebski V; Pajic M; Davis ME; Arkell OSM; Kopecky C; Gonzales-Aloy E; Ishak A; Erkan M; Morton JP; Kavallaris M; Gunning PW; Hardeman EC; Johns A; Gill AJ; Whan RM; Mawson A; Pitiyarachchi O; McCarroll JA; Phillips PA, 2026, 'βIII-tubulin can act as a brake on extrinsic apoptosis in pancreatic cancer', Cell Death and Disease, 17, http://dx.doi.org/10.1038/s41419-026-08657-6

Acosta AM; Gonzales-Aloy E; Ahmed-Cox A; Kurniawan N; Sivaram A; Tsoli M; Janjua T; Kokil G; Ziegler D; Mccarroll J; Turecht K; Popat A; Kumeria T; Kavallaris M, 2026, 'ID #811 Modelling the human blood-brain barrier in 3D to accelerate nanoparticle delivery strategies for brain cancer', Neuro-Oncology Pediatrics, 2, pp. wuag026.339, http://dx.doi.org/10.1093/neuped/wuag026.339

Minchaca AZ; Bertoldo J; Graber P; Bae DH; Jayatilleke N; Mayoh C; Stringer BW; Ludlow L; Kavallaris M; Merlot AM; Minchaca Acosta A, 2026, 'Surface Proteomic Analysis Reveals the Presence of Noncanonical Cell Membrane Endoplasmic Reticulum Chaperones in High-Grade Gliomas', Journal of Proteome Research, 25, pp. 169 - 184, http://dx.doi.org/10.1021/acs.jproteome.5c00616

Feng Y; Cao Y; Kavallaris M; Janjua T; Popat A, 2026, 'Advanced Materials for Biologics Delivery to Brain Tumors', Advanced Materials, http://dx.doi.org/10.1002/adma.74760

Zhang Y; Johansen MD; Ledger S; Shipley R; Zhao G; Moles E; Turville S; Thordarson P; Hansbro PM; Kavallaris M; Kelleher AD; Ahlenstiel CL, 2026, 'Comparative analysis of clinically approved lipid nanoparticles for intranasal siRNA delivery against SARS-CoV-2', Drug Delivery and Translational Research, http://dx.doi.org/10.1007/s13346-026-02076-y

Lim JL; Zong L; Deng W; Kavallaris M; Gu Z, 2026, 'Precisely Engineering Biomimetic Nanoparticles via Controlled Cell Membrane Coating', Small, http://dx.doi.org/10.1002/smll.75272

Jung MS; Poltavets V; Skhinas JN; Tax G; Kamili A; Xie J; Ghamrawi S; Graber P; Mao J; Wong-Erasmus M; Cui L; Kimpton K; Venkat P; Mayoh C; Lin A; Fleuren EDG; Fordham AM; Barger Z; Grady J; Thomas DM; Du EY; Graf NS; Cowley MJ; Gifford AJ; Fletcher JI; Lau LMS; Dolman MEM; Gooding JJ; Kavallaris M; Dolman E; Hearn B, 2025, 'High-throughput 3D engineered paediatric tumour models for precision medicine', Molecular Systems Biology, 21, pp. 1748 - 1777, http://dx.doi.org/10.1038/s44320-025-00152-y

Ignacio RMC; Forgham H; Ma Z; Jensen A; Sharbeen G; Ruan J; Ziegler DS; Tsoli M; Phillips PA; Mayoh C; Kavallaris M; McCarroll J, 2025, 'Chemotherapy reprograms miRNA expression profiles in apoptotic extracellular vesicles from medulloblastoma cells, regulating pro- and anti-proliferative effects on recipient drug-naïve cells', Cell Communication and Signaling, 23, http://dx.doi.org/10.1186/s12964-025-02241-9

Atkinson C; Kamili A; Tactacan CM; Jayatilleke N; Rosser SPA; Saletta F; Gana CC; Graber P; Wanninayaka A; Ignacio RMC; Kavallaris M; Gifford AJ; Lock RB; Norris MD; Haber M; Mayoh C; Nath CE; Trahair TN; Fletcher JI, 2025, 'P-glycoprotein as a chemotherapy resistance mechanism and biomarker of poor response in high-risk neuroblastoma', Ejc Paediatric Oncology, 6, pp. 100478, http://dx.doi.org/10.1016/j.ejcped.2025.100478

Joyce P; Allen CJ; Alonso MJ; Ashford M; Bradbury MS; Germain M; Kavallaris M; Langer R; Lammers T; Peracchia MT; Popat A; Prestidge CA; Rijcken CJF; Sarmento B; Schmid RB; Schroeder A; Subramaniam S; Thorn CR; Whitehead KA; Zhao CX; Santos HA, 2024, 'A translational framework to DELIVER nanomedicines to the clinic', Nature Nanotechnology, 19, pp. 1597 - 1611, http://dx.doi.org/10.1038/s41565-024-01754-7

Graber P; Dolman MEM; Jung MS; Kavallaris M, 2024, 'Ex Vivo Modeling of the Tumor Microenvironment to Develop Therapeutic Strategies for Gliomas', Advanced Therapeutics, 7, http://dx.doi.org/10.1002/adtp.202300442

Hassan N; Yi H; Malik B; Gaspard-Boulinc L; Samaraweera SE; Casolari DA; Seneviratne J; Balachandran A; Chew T; Duly A; Carter DR; Cheung BB; Norris M; Haber M; Kavallaris M; Marshall GM; Zhang XD; Liu T; Wang J; Liebermann DA; D'Andrea RJ; Wang JY, 2024, 'Loss of the stress sensor GADD45A promotes stem cell activity and ferroptosis resistance in LGR4/HOXA9-dependent AML', Blood, 144, pp. 84 - 98, http://dx.doi.org/10.1182/blood.2024024072

Forgham H; Zhu J; Huang X; Zhang C; Biggs H; Liu L; Wang YC; Fletcher N; Humphries J; Cowin G; Mardon K; Kavallaris M; Thurecht K; Davis TP; Qiao R, 2024, 'Multifunctional Fluoropolymer-Engineered Magnetic Nanoparticles to Facilitate Blood-Brain Barrier Penetration and Effective Gene Silencing in Medulloblastoma', Advanced Science, 11, http://dx.doi.org/10.1002/advs.202401340

Holliday H; Yang J; Dodson E; Nikolic I; Kamili A; Wheatley M; Deng N; Alexandrou S; Davis TP; Kavallaris M; Caldon CE; McCarroll J; De Preter K; Mestdagh P; Marshall GM; Simpson KJ; Fletcher J; Swarbrick A, 2024, 'Erratum: miR-99b-5p, miR-380-3p, and miR-485-3p are novel chemosensitizing miRNAs in high-risk neuroblastoma (Molecular Therapy (2022) 30(3) (1119–1134), (S1525001622000041), (10.1016/j.ymthe.2022.01.004))', Molecular Therapy, 32, pp. 2031 - 2033, http://dx.doi.org/10.1016/j.ymthe.2024.05.008

Evans L; Walker R; MacDiarmid J; Brahmbhatt H; Anazodo A; McCowage G; Gifford AJ; Kavallaris M; Trahair T; Ziegler DS, 2024, 'A Phase 1 Study of Intravenous EGFR-ErbituxEDVsMIT in Children with Solid or CNS Tumours Expressing Epidermal Growth Factor Receptor', Targeted Oncology, 19, pp. 333 - 342, http://dx.doi.org/10.1007/s11523-024-01051-2

Logan A; Howard CB; Huda P; Kimpton K; Ma Z; Thurecht KJ; McCarroll JA; Moles E; Kavallaris M; Moles Meler E, 2024, 'Targeted delivery of polo-like kinase 1 siRNA nanoparticles using an EGFR-PEG bispecific antibody inhibits proliferation of high-risk neuroblastoma.', Journal of Controlled Release, 367, pp. 806 - 820, http://dx.doi.org/10.1016/j.jconrel.2024.02.007

Mohamed SMA; Schofield P; McCalmont H; Moles E; Friedrich KH; Kavallaris M; Christ D; Bayat N; Lock RB, 2024, 'An antibody fragment-decorated liposomal conjugate targets Philadelphia-like acute lymphoblastic leukemia', International Journal of Biological Macromolecules, 254, http://dx.doi.org/10.1016/j.ijbiomac.2023.127596

Moles E; Chang DW; Mansfeld FM; Duly A; Kimpton K; Logan A; Howard CB; Thurecht KJ; Kavallaris M; Moles Meler E, 2024, 'EGFR Targeting of Liposomal Doxorubicin Improves Recognition and Suppression of Non-Small Cell Lung Cancer', International Journal of Nanomedicine, 19, pp. 3623 - 3639, http://dx.doi.org/10.2147/IJN.S450534

Graber P; Dolman MEM; Jung M; Kavallaris M, 2024, 'Ex Vivo Modeling of the Tumor Microenvironment to Develop Therapeutic Strategies for Gliomas (Adv. Therap. 11/2024)', Advanced Therapeutics, 7, http://dx.doi.org/10.1002/adtp.202470026

Du EY; Jung MS; Skhinas J; Tolentino MAK; Noy J; Jamshidi N; Houng JL; Tjandra KC; Engel M; Utama R; Tilley RD; Kavallaris M; Gooding JJ, 2023, '3D Bioprintable Hydrogel with Tunable Stiffness for Exploring Cells Encapsulated in Matrices of Differing Stiffnesses', ACS Applied Bio Materials, 6, pp. 4603 - 4612, http://dx.doi.org/10.1021/acsabm.3c00334

Moles E; Howard CB; Huda P; Karsa M; McCalmont H; Kimpton K; Duly A; Chen Y; Huang Y; Tursky ML; Ma D; Bustamante S; Pickford R; Connerty P; Omari S; Jolly CJ; Joshi S; Shen S; Pimanda JE; Dolnikov A; Cheung LC; Kotecha RS; Norris MD; Haber M; de Bock CE; Somers K; Lock RB; Thurecht KJ; Kavallaris M, 2023, 'Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia', Science translational medicine, 15, pp. eabm1262 - eabm1262, http://dx.doi.org/10.1126/scitranslmed.abm1262

Janjua TI; Cao Y; Ahmed-Cox A; Raza A; Moniruzzaman M; Akhter DT; Fletcher NL; Kavallaris M; Thurecht KJ; Popat A, 2023, 'Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma', Journal of Controlled Release, 357, pp. 161 - 174, http://dx.doi.org/10.1016/j.jconrel.2023.03.040

Gonzales-Aloy E; Ahmed-Cox A; Tsoli M; Ziegler DS; Kavallaris M, 2023, 'From cells to organoids: The evolution of blood-brain barrier technology for modelling drug delivery in brain cancer', Advanced Drug Delivery Reviews, 196, http://dx.doi.org/10.1016/j.addr.2023.114777

Suwannakot P; Nemec S; Peres NG; Du EY; Kilian KA; Gaus K; Kavallaris M; Gooding JJ, 2023, 'Electrostatic Assembly of Multiarm PEG-Based Hydrogels as Extracellular Matrix Mimics: Cell Response in the Presence and Absence of RGD Cell Adhesive Ligands', ACS Biomaterials Science and Engineering, 9, pp. 1362 - 1376, http://dx.doi.org/10.1021/acsbiomaterials.2c01252

Brayford S; Duly A; Teo WS; Dwarte T; Gonzales-Aloy E; Ma Z; McVeigh L; Failes TW; Arndt GM; McCarroll JA; Kavallaris M, 2023, 'βIII-tubulin suppression enhances the activity of Amuvatinib to inhibit cell proliferation in c-Met positive non-small cell lung cancer cells', Cancer Medicine, 12, pp. 4455 - 4471, http://dx.doi.org/10.1002/cam4.5128

Nguyen DHT; Utama RH; Tjandra KC; Suwannakot P; Du EY; Kavallaris M; Tilley RD; Gooding JJ, 2023, 'Tuning the Mechanical Properties of Multiarm RAFT-Based Block Copolyelectrolyte Hydrogels via Ionic Cross-Linking for 3D Cell Cultures', Biomacromolecules, 24, pp. 57 - 68, http://dx.doi.org/10.1021/acs.biomac.2c00632

Jung MS; Ghamrawi S; Du EY; Gooding JJ; Kavallaris M, 2022, 'Advances in 3D Bioprinting for Cancer Biology and Precision Medicine: From Matrix Design to Application', Advanced Healthcare Materials, 11, pp. 2200690, http://dx.doi.org/10.1002/adhm.202200690

Jung MS; Skhinas JN; Du EY; Tolentino MAK; Utama RH; Engel M; Volkerling A; Sexton A; O'Mahony AP; Ribeiro JCC; Gooding JJ; Kavallaris M, 2022, 'A high-throughput 3D bioprinted cancer cell migration and invasion model with versatile and broad biological applicability', Biomaterials Science, 10, pp. 5876 - 5887, http://dx.doi.org/10.1039/d2bm00651k

Cong VT; Houng JL; Kavallaris M; Chen X; Tilley RD; Gooding JJ, 2022, 'How can we use the endocytosis pathways to design nanoparticle drug-delivery vehicles to target cancer cells over healthy cells?', Chemical Society Reviews, 51, pp. 7531 - 7559, http://dx.doi.org/10.1039/d1cs00707f

Muskovic W; Slavich E; Maslen B; Kaczorowski DC; Cursons J; Crampin E; Kavallaris M, 2022, 'High temporal resolution RNA-seq time course data reveals widespread synchronous activation between mammalian lncRNAs and neighboring protein-coding genes', Genome Research, 32, pp. 1463 - 1473, http://dx.doi.org/10.1101/gr.276818.122

Sumer-Bayraktar Z; Fife CM; Byrne FL; Kavallaris M; Packer NH, 2022, 'Membrane glycome is impacted by the cell culturing mode of neuroblastoma cells with differing migration and invasion potential', Glycobiology, 32, pp. 588 - 599, http://dx.doi.org/10.1093/glycob/cwac016

Ma Z; Wong SW; Forgham H; Esser L; Lai M; Leiske MN; Kempe K; Sharbeen G; Youkhana J; Mansfeld F; Quinn JF; Phillips PA; Davis TP; Kavallaris M; McCarroll JA, 2022, 'Aerosol delivery of star polymer-siRNA nanoparticles as a therapeutic strategy to inhibit lung tumor growth', Biomaterials, 285, http://dx.doi.org/10.1016/j.biomaterials.2022.121539

Duly AMP; Kao FCL; Teo WS; Kavallaris M, 2022, 'βIII-Tubulin Gene Regulation in Health and Disease', Frontiers in Cell and Developmental Biology, 10, http://dx.doi.org/10.3389/fcell.2022.851542

Holliday H; Yang J; Dodson E; Nikolic I; Kamili A; Wheatley M; Deng N; Alexandrou S; Davis TP; Kavallaris M; Caldon CE; McCarroll J; De Preter K; Mestdagh P; Marshall GM; Simpson KJ; Fletcher J; Swarbrick A, 2022, 'miR-99b-5p, miR-380-3p, and miR-485-3p are novel chemosensitizing miRNAs in high-risk neuroblastoma', Molecular Therapy, 30, pp. 1119 - 1134, http://dx.doi.org/10.1016/j.ymthe.2022.01.004

Parker AL; Teo WS; Brayford S; Moorthi UK; Arumugam S; Ferguson C; Parton RG; McCarroll JA; Kavallaris M, 2022, 'βIII-Tubulin Structural Domains Regulate Mitochondrial Network Architecture in an Isotype-Specific Manner', Cells, 11, http://dx.doi.org/10.3390/cells11050776

Ahmed-Cox A; Macmillan AM; Pandzic E; Whan RM; Kavallaris M, 2022, 'Application of Rapid Fluorescence Lifetime Imaging Microscopy (RapidFLIM) to Examine Dynamics of Nanoparticle Uptake in Live Cells', Cells, 11, http://dx.doi.org/10.3390/cells11040642

Karsa M; Ronca E; Bongers A; Mariana A; Moles E; Failes TW; Arndt GM; Cheung LC; Kotecha RS; Kavallaris M; Haber M; Norris MD; Henderson MJ; Xiao L; Somers K; Moles Meler E, 2022, 'Systematic In Vitro Evaluation of a Library of Approved and Pharmacologically Active Compounds for the Identification of Novel Candidate Drugs for KMT2A-Rearranged Leukemia', Frontiers in Oncology, 11, pp. 779859, http://dx.doi.org/10.3389/fonc.2021.779859

Upton DH; Ung C; George SM; Tsoli M; Kavallaris M; Ziegler DS, 2022, 'Challenges and opportunities to penetrate the blood-brain barrier for brain cancer therapy', Theranostics, 12, pp. 4734 - 4752, http://dx.doi.org/10.7150/THNO.69682

Ahmed-Cox A; Pandzic E; Johnston ST; Heu C; McGhee J; Mansfeld FM; Crampin EJ; Davis TP; Whan RM; Kavallaris M, 2022, 'Spatio-temporal analysis of nanoparticles in live tumor spheroids impacted by cell origin and density', Journal of Controlled Release, 341, pp. 661 - 675, http://dx.doi.org/10.1016/j.jconrel.2021.12.014

Mohamed SMA; Wohlmann A; Schofield P; Sia KCS; McCalmont H; Savvides SN; Verstraete K; Kavallaris M; Christ D; Friedrich KH; Bayat N; Lock RB, 2021, 'A recombinant antibody fragment directed to the thymic stromal lymphopoietin receptor (CRLF2) efficiently targets pediatric Philadelphia chromosome-like acute lymphoblastic leukemia', International Journal of Biological Macromolecules, 190, pp. 214 - 223, http://dx.doi.org/10.1016/j.ijbiomac.2021.08.194

Janjua TI; Ahmed-Cox A; Meka AK; Mansfeld FM; Forgham H; Ignacio RMC; Cao Y; McCarroll JA; Mazzieri R; Kavallaris M; Popat A, 2021, 'Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma', Nanoscale, 13, pp. 16909 - 16922, http://dx.doi.org/10.1039/d1nr03553c

Connerty P; Moles E; de Bock CE; Jayatilleke N; Smith JL; Meshinchi S; Mayoh C; Kavallaris M; Lock RB, 2021, 'Development of siRNA-loaded lipid nanoparticles targeting long non-coding RNA LINC01257 as a novel and safe therapeutic approach for t(8;21) pediatric acute myeloid leukemia', Pharmaceutics, 13, http://dx.doi.org/10.3390/pharmaceutics13101681

Utama RH; Tan VTG; Tjandra KC; Sexton A; Nguyen DHT; O'Mahony AP; Du EY; Tian P; Ribeiro JCC; Kavallaris M; Gooding JJ, 2021, 'A Covalently Crosslinked Ink for Multimaterials Drop-on-Demand 3D Bioprinting of 3D Cell Cultures', Macromolecular Bioscience, 21, pp. e2100125, http://dx.doi.org/10.1002/mabi.202100125

Conte C; Monteiro PF; Gurnani P; Stolnik S; Ungaro F; Quaglia F; Clarke P; Grabowska A; Kavallaris M; Alexander C, 2021, 'Multi-component bioresponsive nanoparticles for synchronous delivery of docetaxel and TUBB3 siRNA to lung cancer cells', Nanoscale, 13, pp. 11414 - 11426, http://dx.doi.org/10.1039/d1nr02179f

Janjua TI; Rewatkar P; Ahmed-Cox A; Saeed I; Mansfeld FM; Kulshreshtha R; Kumeria T; Ziegler DS; Kavallaris M; Mazzieri R; Popat A, 2021, 'Frontiers in the treatment of glioblastoma: Past, present and emerging', Advanced Drug Delivery Reviews, 171, pp. 108 - 138, http://dx.doi.org/10.1016/j.addr.2021.01.012

Putra V; Hulme AJ; Tee AE; Sun JQJ; Atmadibrata B; Ho N; Chen J; Gao J; Norris MD; Haber M; Kavallaris M; Henderson MJ; McCarroll J; Trahair T; Liu T; Liu PY, 2021, 'The RNA-helicase DDX21 upregulates CEP55 expression and promotes neuroblastoma', Molecular Oncology, 15, pp. 1162 - 1179, http://dx.doi.org/10.1002/1878-0261.12906

Ung C; Tsoli M; Liu J; Cassano D; Pocoví-Martínez S; Upton DH; Ehteda A; Mansfeld FM; Failes TW; Farfalla A; Katsinas C; Kavallaris M; Arndt GM; Vittorio O; Cirillo G; Voliani V; Ziegler DS, 2021, 'Doxorubicin-loaded gold nanoarchitectures as a therapeutic strategy against diffuse intrinsic pontine glioma', Cancers, 13, pp. 1 - 20, http://dx.doi.org/10.3390/cancers13061278

Grohmann C; Walker F; Devlin M; Luo MX; Chüeh AC; Doherty J; Vaillant F; Ho GY; Wakefield MJ; Weeden CE; Kamili A; Murray J; Po’uha ST; Weinstock J; Kane SR; Faux MC; Broekhuizen E; Zheng Y; Shield-Artin K; Kershaw NJ; Tan CW; Witchard HM; Ebert G; Charman SA; Street I; Kavallaris M; Haber M; Fletcher JI; Asselin-Labat ML; Scott CL; Visvader JE; Lindeman GJ; Watson KG; Burgess AW; Lessene G, 2021, 'Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors', Cell Death and Disease, 12, http://dx.doi.org/10.1038/s41419-020-03269-0

Yang Y; Mansfeld FM; Kavallaris M; Gaus K; Tilley RD; Gooding JJ, 2021, 'Monitoring the heterogeneity in single cell responses to drugs using electrochemical impedance and electrochemical noise', Chemical Science, 12, pp. 2558 - 2566, http://dx.doi.org/10.1039/d0sc05489e

Yeola A; Subramanian S; Oliver RA; Lucas CA; Thoms JAI; Yan F; Olivier J; Chacon D; Tursky ML; Hung T; Power C; Hardy P; D D; McCarroll J; Kavallaris M; Hesson LB; Beck D; Curtis DJ; Wong JWH; Hardeman EC; Walsh WR; Mobbs R; Chandrakanthan V; Pimanda JE; Kilian K; Potas J; Ma D; Srivastava P; Chacon Fajardo D, 2021, 'Induction of Muscle Regenerative Multipotent Stem Cells from Human Adipocytes by PDGF-AB and 5-Azacytidine', Science Advances, 7, pp. 2020.06.04.130872 - 2020.06.04.130872, http://dx.doi.org/10.1126/sciadv.abd1929

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