By Dr Anne Poljak

Journal articles

Jeżewski RC; Poljak A; Mather KA; Sachdev PS; Shepherd CE, 2020, 'The prevalence of limbic‐predominant age‐related TDP‐43 encephalopathy in the Sydney brain bank', Alzheimer's & Dementia, 16, http://dx.doi.org/10.1002/alz.037885

Wong MWK; Braidy N; Pickford R; Sachdev PS; Poljak A, 2019, 'Comparison of Single Phase and Biphasic Extraction Protocols for Lipidomic Studies Using Human Plasma', Frontiers in Neurology, 10, pp. 1 - 11, http://dx.doi.org/10.3389/fneur.2019.00879

Lam T; McLean M; Hayden A; Poljak A; Cheema B; Gurney H; Stone G; Bahl N; Reddy N; Shahidipour H; Birzniece V, 2019, 'A potent liver-mediated mechanism for loss of muscle mass during androgen deprivation therapy', Endocrine Connections, 8, pp. 605 - 615, http://dx.doi.org/10.1530/EC-19-0179

Clement J; Wong M; Poljak A; Sachdev P; Braidy N, 2019, 'The Plasma NAD⁺ Metabolome Is Dysregulated in "normal" Aging', Rejuvenation Research, 22, pp. 121 - 130, http://dx.doi.org/10.1089/rej.2018.2077

Wong MWK; Braidy N; Pickford R; Vafaee F; Crawford J; Muenchhoff J; Schofield P; Attia J; Brodaty H; Sachdev P; Poljak A, 2019, 'Plasma lipidome variation during the second half of the human lifespan is associated with age and sex but minimally with BMI', Plos One, 14, pp. e0214141, http://dx.doi.org/10.1371/journal.pone.0214141

Braidy N; Berg J; Clement J; Khorshidi F; Poljak A; Jayasena T; Grant R; Sachdev PS, 2019, 'Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes', Antioxidants and Redox Signaling, 30, pp. 251 - 294, http://dx.doi.org/10.1089/ars.2017.7269

Wong MWK; Braidy N; Crawford J; Pickford R; Song F; Mather KA; Attia J; Brodaty H; Sachdev P; Poljak A, 2019, 'APOE Genotype Differentially Modulates Plasma Lipids in Healthy Older Individuals, with Relevance to Brain Health', Journal of Alzheimer S Disease, 72, pp. 703 - 716, http://dx.doi.org/10.3233/JAD-190524

Liu Y; Braidy N; Poljak A; Chan DK; Sachdev PS, 2018, 'Cerebral small vessel disease and the risk of Alzheimer's disease: A systematic review', Ageing Research Reviews, http://dx.doi.org/10.1016/j.arr.2018.06.002

Shum AMY; Poljak A; Bentley NL; Turner N; Tan TC; Polly P, 2018, 'Proteomic profiling of skeletal and cardiac muscle in cancer cachexia: Alterations in sarcomeric and mitochondrial protein expression', Oncotarget, 9, pp. 22001 - 22022, http://dx.doi.org/10.18632/oncotarget.25146

Stefanoska K; Volkerling A; Bertz J; Poljak A; Ke YD; Ittner LM; Ittner A, 2018, 'An N-terminal motif unique to primate tau enables differential protein–protein interactions', Journal of Biological Chemistry, 293, pp. 3710 - 3719, http://dx.doi.org/10.1074/jbc.RA118.001784

Caplan GA; Tai J; Mohd Hanizan F; McVeigh CL; Hill MA; Poljak A, 2017, 'Cerebrospinal Fluid Apolipoprotein E Levels in Delirium', Dementia and Geriatric Cognitive Disorders Extra, 7, pp. 240 - 248, http://dx.doi.org/10.1159/000477847

Muenchhoff J; Song F; Poljak A; Crawford JD; Mather KA; Kochan NA; Yang Z; Trollor JN; Reppermund S; Maston K; Theobald A; Kirchner-Adelhardt S; Kwok JB; Richmond RL; McEvoy M; Attia J; Schofield PW; Brodaty H; Sachdev PS, 2017, 'Plasma apolipoproteins and physical and cognitive health in very old individuals', Neurobiology of Aging, 55, pp. 49 - 60, http://dx.doi.org/10.1016/j.neurobiolaging.2017.02.017

Williams TJ; Liao Y; Ye J; Kuchel RP; Poljak A; Raftery MJ; Cavicchioli R, 2017, 'Cold adaptation of the Antarctic haloarchaea Halohasta litchfieldiae and Halorubrum lacusprofundi', Environmental Microbiology, 19, pp. 2210 - 2227, http://dx.doi.org/10.1111/1462-2920.13705

Jayawardena MB; Yee LH; Poljak A; Cavicchioli R; Kjelleberg SJ; Siddiqui KS, 2017, 'Enhancement of lipase stability and productivity through chemical modification and its application to latex-based polymer emulsions', Process Biochemistry, 57, pp. 131 - 140, http://dx.doi.org/10.1016/j.procbio.2017.03.014

Braidy N; Poljak A; Marjo C; Rutlidge H; Rich A; Jugder BE; Jayasena T; Inestrosa NC; Sachdev PS, 2017, 'RETRACTED: Corrigendum: Identification of Cerebral Metal Ion Imbalance in the Brain of Ageing Octodon degus', Frontiers in Aging Neuroscience, 9, pp. 134, http://dx.doi.org/10.3389/fnagi.2017.00134

Lam T; Poljak A; McLean M; Bahl N; Ho KKY; Birzniece V, 2017, 'Testosterone prevents protein loss via the hepatic urea cycle in human', European Journal of Endocrinology, 176, pp. 489 - 496, http://dx.doi.org/10.1530/EJE-16-0868

Braidy N; Poljak A; Marjo C; Rutlidge H; Rich A; Jugder B-E; Jayasena T; Inestrosa N; Sachdev P, 2017, 'Identification of cerebral metal ion imbalance in the brain of ageing Octodon degus', Frontiers in Aging Neuroscience, 9, pp. 66 - 66, http://dx.doi.org/10.3389/fnagi.2017.00066

Petersons CJ; Mangelsdorf BL; Poljak A; Smith MD; Greenfield JR; Thompson CH; Burt MG, 2017, 'Low dose prednisolone and insulin sensitivity differentially affect arterial stiffness and endothelial function: An open interventional and cross-sectional study', Atherosclerosis, 258, pp. 34 - 39, http://dx.doi.org/10.1016/j.atherosclerosis.2017.01.033

Chen DLT; Brown R; Liess C; Poljak A; Xu A; Zhang J; Trenell M; Jenkins A; Chisholm D; Samocha-Bonet D; Macefield VG; Greenfield JR; Chen D; Milliken S; Goodnow C, 2017, 'Muscle sympathetic nerve activity is associated with liver insulin sensitivity in obese non-diabetic men', Frontiers in Physiology, 8, pp. 101, http://dx.doi.org/10.3389/fphys.2017.00101

Wong MW; Braidy N; Poljak A; Pickford R; Thambisetty M; Sachdev PS, 2017, 'Dysregulation of lipids in Alzheimer's disease and their role as potential biomarkers', Alzheimers Dement, 13, pp. 810 - 827, http://dx.doi.org/10.1016/j.jalz.2017.01.008

Braidy N; Jugder B-E; Poljak A; Jayasena T; Nabavi SM; Sachdev P; Grant R, 2017, 'Molecular targets of Tannic Acid in Alzheimer’s disease', Curr Alzheimer Res, 14, http://dx.doi.org/10.2174/1567205014666170206163158

, 2017, 'Erratum for the Report “Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer’s mice” by A. Ittner, S. W. Chua, J. Bertz, A. Volkerling, J. van der Hoven, A. Gladbach, M. Przybyla, M. Bi, A. van Hummel, C. H. Stevens, S. Ippati, L. S. Suh, A. Macmillan, G. Sutherland, J. J. Kril, A. P. G. Silva, J. P. Mackay, A. Poljak, F. Delerue, Y. D. Ke, L. M. Ittner', Science, 355, pp. eaam9523, http://dx.doi.org/10.1126/science.aam9523

Poljak A; Sachdev PS, 2017, 'Plasma amyloid beta peptides: an Alzheimer’s conundrum or a more accessible Alzheimer’s biomarker?', Expert Review of Neurotherapeutics, 17, pp. 3 - 5, http://dx.doi.org/10.1080/14737175.2016.1217156

Lam T; McLean M; Bahl N; Poljak A; Ho KKY; Birzniece V, 2017, 'Testosterone prevents protein loss via the hepatic urea cycle', CLINICAL ENDOCRINOLOGY, 86, pp. 14 - 14, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000393453600038&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Wong MW; Braidy N; Poljak A; Sachdev PS, 2017, 'The application of lipidomics to biomarker research and pathomechanisms in Alzheimer's disease', Current Opinion in Psychiatry, 30, pp. 136 - 144, http://dx.doi.org/10.1097/YCO.0000000000000303

Liao Y; Williams TJ; Ye J; Charlesworth J; Burns BP; Poljak A; Raftery MJ; Cavicchioli R, 2016, 'Morphological and proteomic analysis of biofilms from the Antarctic archaeon, Halorubrum lacusprofundi', Scientific Reports, 6, pp. 37454, http://dx.doi.org/10.1038/srep37454

Ittner A; Chua SW; Bertz J; Volkerling A; Van Der Hoven J; Gladbach A; Przybyla M; Bi M; Van Hummel A; Stevens CH; Ippati S; Suh LS; Macmillan A; Sutherland G; Kril JJ; Silva APG; Mackay J; Poljak A; Delerue F; Ke YD; Ittner LM, 2016, 'Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice', Science, 354, pp. 904 - 908, http://dx.doi.org/10.1126/science.aah6205

Jayasena T; Poljak A; Braidy N; Zhong L; Rowlands B; Muenchhoff J; Grant R; Smythe G; Teo C; Raftery M; Sachdev PS, 2016, 'Application of targeted mass spectrometry for the quantification of sirtuins in the central nervous system', Scientific Reports, 6, pp. 35391 - 35391, http://dx.doi.org/10.1038/srep35391

Liao Y; Williams TJ; Walsh JC; Ji M; Poljak A; Curmi PMG; Duggin IG; Cavicchioli R, 2016, 'Developing a genetic manipulation system for the Antarctic archaeon, Halorubrum lacusprofundi: Investigating acetamidase gene function', Scientific Reports, 6, pp. 34639, http://dx.doi.org/10.1038/srep34639

Muenchhoff J; Poljak A; Thalamuthu A; Gupta VB; Chatterjee P; Raftery M; Masters CL; Morris JC; Bateman RJ; Fagan AM; Martins RN; Sachdev PS, 2016, 'Changes in the plasma proteome at asymptomatic and symptomatic stages of autosomal dominant Alzheimer's disease', Scientific Reports, 6, pp. 29078 - 29078, http://dx.doi.org/10.1038/srep29078

Braidy N; Jugder BE; Poljak A; Jayasena T; Mansour H; Nabavi SM; Sachdev P; Grant R, 2016, 'Resveratrol as a potential therapeutic candidate for the treatment and management of alzheimer’s disease', Current Topics in Medicinal Chemistry, 16, pp. 1951 - 1960, http://dx.doi.org/10.2174/1568026616666160204121431

Mather KA; Thalamuthu A; Oldmeadow C; Song F; Armstrong NJ; Poljak A; Holliday EG; McEvoy M; Kwok JB; Assareh AA; Reppermund S; Kochan NA; Lee T; Ames D; Wright MJ; Trollor JN; Schofield PW; Brodaty H; Scott RJ; Schofield PR; Attia JR; Sachdev PS, 2016, 'Genome-wide significant results identified for plasma apolipoprotein H levels in middle-aged and older adults.', Sci Rep, 6, pp. 23675, http://dx.doi.org/10.1038/srep23675

Chen DL; Liess C; Poljak A; Xu A; Zhang J; Thoma C; Trenell M; Milner B; Jenkins AB; Chisholm DJ; Samocha-Bonet D; Greenfield JR, 2016, 'Erratum: Phenotypic Characterization of Insulin-Resistant and Insulin-Sensitive Obesity (Journal of Clinical Endocrinology and Metabolism 2015 100(11): (4082-4091)); doi: 10.1210/jc.2015-2712', Journal of Clinical Endocrinology and Metabolism, 101, pp. 757, http://dx.doi.org/10.1210/jc.2015-4260

Braidy N; Essa MM; Poljak A; Selvaraju S; Al-Adawi S; Manivasagm T; Thenmozhi AJ; Ooi L; Sachdev P; Guillemin GJ, 2016, 'Consumption of pomegranates improves synaptic function in a transgenic mice model of Alzheimer's disease', Oncotarget, 7, pp. 64589 - 64604, http://dx.doi.org/10.18632/oncotarget.10905

Yeung ACY; D'Agostino PM; Poljak A; McDonald J; Bligh MW; Waite TD; Neilan BA, 2016, 'Physiological and proteomic responses of continuous cultures of Microcystis aeruginosa PCC 7806 to changes in iron bioavailability and growth rate', Applied and Environmental Microbiology, 82, pp. 5918 - 5929, http://dx.doi.org/10.1128/AEM.01207-16

McGill M; Shum A; Poljak A; Tan T; Polly P, 2016, 'Cancer Cachexia Induced Changes in Sarcomeric and Energy Homeostasis: Proteomic Signatures in the Heart', Heart, Lung and Circulation, 25, pp. S99 - S100, http://dx.doi.org/10.1016/j.hlc.2016.06.236

Poljak A; Crawford JD; Smythe GA; Brodaty H; Slavin MJ; Kochan NA; Trollor JN; Wen W; Mather KA; Assareh AA; Ng PC; Sachdev PS, 2016, 'The Relationship Between Plasma Aβ Levels, Cognitive Function and Brain Volumetrics: Sydney Memory and Ageing Study.', Current Alzheimer research, 13, pp. 243 - 255, http://dx.doi.org/10.2174/1567205013666151218150202

Chen DL; Liess C; Poljak A; Xu A; Zhang J; Thoma C; Trenell M; Milner B; Jenkins AB; Chisholm DJ; Samocha-Bonet D; Greenfield JR, 2015, 'Phenotypic characterization of insulin-resistant and insulin-sensitive obesity', Journal of Clinical Endocrinology and Metabolism, 100, pp. 4082 - 4091, http://dx.doi.org/10.1210/jc.2015-2712

Braidy N; Poljak A; Grant R; Jayasena T; Mansour H; Chan-Ling T; Smythe G; Sachdev P; Guillemin GJ, 2015, 'Differential expression of sirtuins in the aging rat brain', Frontiers in Cellular Neuroscience, 9, pp. 167, http://dx.doi.org/10.3389/fncel.2015.00167

Braidy N; Poljak A; Jayasena T; Mansour H; Inestrosa NC; Sachdev PS, 2015, 'Accelerating Alzheimer's research through 'natural' animal models', Current Opinion in Psychiatry, 28, pp. 155 - 164, http://dx.doi.org/10.1097/YCO.0000000000000137

Ertan H; Cassel C; Verma A; Poljak A; Charlton T; Aldrich-Wright J; Omar SM; Siddiqui KS; Cavicchioli R, 2015, 'A new broad specificity alkaline metalloprotease from a Pseudomonas sp. isolated from refrigerated milk: Role of calcium in improving enzyme productivity', Journal of Molecular Catalysis B Enzymatic, 113, pp. 1 - 8, http://dx.doi.org/10.1016/j.molcatb.2014.12.010

Lazarus J; Mather KA; Armstrong NJ; Song F; Poljak A; Thalamuthu A; Lee T; Kochan NA; Brodaty H; Wright MJ; Ames D; Sachdev PS; Kwok JBJ, 2015, 'DNA methylation in the apolipoprotein-A1 gene is associated with episodic memory performance in healthy older individuals', Journal of Alzheimer's Disease, 44, pp. 175 - 182, http://dx.doi.org/10.3233/JAD-141314

Muenchhoff J; Poljak A; Song F; Raftery M; Brodaty H; Duncan M; McEvoy M; Attia J; Schofield PW; Sachdev PS, 2015, 'Plasma protein profiling of mild cognitive impairment and Alzheimer's disease across two independent cohorts', Journal of Alzheimer's Disease, 43, pp. 1355 - 1373, http://dx.doi.org/10.3233/JAD-141266

Jayasena T; Poljak A; Braidy N; Smythe G; Raftery M; Hill M; Brodaty H; Trollor J; Kochan N; Sachdev P, 2015, 'Upregulation of glycolytic enzymes, mitochondrial dysfunction and increased cytotoxicity in glial cells treated with Alzheimer's disease plasma.', PLoS One, 10, pp. e0116092, http://dx.doi.org/10.1371/journal.pone.0116092

Hou X; McMillan M; Coumans JVF; Poljak A; Raftery MJ; Pereg L, 2014, 'Cellular responses during morphological transformation in Azospirillum brasilense and its flcA knockout mutant', Plos One, 9, http://dx.doi.org/10.1371/journal.pone.0114435

Coumans JVF; Gau D; Poljak A; Wasinger V; Roy P; Moens PDJ, 2014, 'Profilin-1 overexpression in MDA-MB-231 breast cancer cells is associated with alterations in proteomics biomarkers of cell proliferation, survival, and motility as revealed by global proteomics analyses', OMICS A Journal of Integrative Biology, 18, pp. 778 - 791, http://dx.doi.org/10.1089/omi.2014.0075

Lee P; Birzniece V; Umpleby AM; Poljak A; Ho KKY, 2014, 'Formoterol, a Highly β2-Selective Agonist, Induces Gender-Dimorphic Whole Body Leucine Metabolism in Humans', Metabolism: Clinical and Experimental, http://dx.doi.org/10.1016/j.metabol.2014.12.005

Braidy N; Poljak A; Grant R; Jayasena T; Mansour H; Chan-Ling T; Guillemin GJ; Smythe G; Sachdev P, 2014, 'Mapping NAD+ metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence', Biogerontology, 15, pp. 177 - 198, http://dx.doi.org/10.1007/s10522-013-9489-5

Coumans JVF; Gau D; Poljak A; Wasinger V; Roy P; Moens P, 2014, 'Green fluorescent protein expression triggers proteome changes in breast cancer cells', Experimental Cell Research, 320, pp. 33 - 45, http://dx.doi.org/10.1016/j.yexcr.2013.07.019

Braidy N; Poljak A; Marjo C; Rutlidge H; Rich A; Jayasena T; Inestrosa NC; Sachdev P, 2014, 'Metal and complementary molecular bioimaging in alzheimer's disease', Frontiers in Aging Neuroscience, 6, pp. 138, http://dx.doi.org/10.3389/fnagi.2014.00138

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