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Journal articles

Yang J; Gao C; Liu M; Liu YC; Kwon J; Qi J; Tian X; Stein A; Liu YV; Kong NR; Wu Y; Yin S; Xi J; Chen Z; Kumari K; Wong H; Luo H; Silberstein LE; Thoms JAI; Unnikrishnan A; Pimanda JE; Tenen DG; Chai L, 2021, 'Targeting an Inducible SALL4-Mediated Cancer Vulnerability with Sequential Therapy', Cancer Research, vol. 81, pp. 6018 - 6028, http://dx.doi.org/10.1158/0008-5472.CAN-21-0030

Lorenzi L; Chiu HS; Avila Cobos F; Gross S; Volders PJ; Cannoodt R; Nuytens J; Vanderheyden K; Anckaert J; Lefever S; Tay AP; de Bony EJ; Trypsteen W; Gysens F; Vromman M; Goovaerts T; Hansen TB; Kuersten S; Nijs N; Taghon T; Vermaelen K; Bracke KR; Saeys Y; De Meyer T; Deshpande NP; Anande G; Chen TW; Wilkins MR; Unnikrishnan A; De Preter K; Kjems J; Koster J; Schroth GP; Vandesompele J; Sumazin P; Mestdagh P, 2021, 'Publisher Correction: The RNA Atlas expands the catalog of human non-coding RNAs (Nature Biotechnology, (2021), 39, 11, (1453-1465), 10.1038/s41587-021-00936-1)', Nature Biotechnology, vol. 39, pp. 1467, http://dx.doi.org/10.1038/s41587-021-00996-3

Lorenzi L; Chiu HS; Avila Cobos F; Gross S; Volders PJ; Cannoodt R; Nuytens J; Vanderheyden K; Anckaert J; Lefever S; Tay AP; de Bony EJ; Trypsteen W; Gysens F; Vromman M; Goovaerts T; Hansen TB; Kuersten S; Nijs N; Taghon T; Vermaelen K; Bracke KR; Saeys Y; De Meyer T; Deshpande NP; Anande G; Chen TW; Wilkins MR; Unnikrishnan A; De Preter K; Kjems J; Koster J; Schroth GP; Vandesompele J; Sumazin P; Mestdagh P, 2021, 'The RNA Atlas expands the catalog of human non-coding RNAs', Nature Biotechnology, vol. 39, pp. 1453 - 1465, http://dx.doi.org/10.1038/s41587-021-00936-1

Chandrakanthan V; Rorimpandey P; Zanini F; Chacon D; Kang YC; Knezevic K; Huang Y; Qiao Q; Oliver R; Unnikrishnan A; Carter D; Lee B; Brownlee C; Power C; Mendez-Ferrer S; Enikolopov G; Walsh W; Göttgens B; Taoudi S; Beck D; Pimanda J, 2021, 'Mesoderm-Derived PDGFRA+ Cells Regulate the Emergence of Hematopoietic Stem Cells in the Dorsal Aorta', , http://dx.doi.org/10.1101/2021.08.08.455592

Liu L; Vujovic A; Deshpande N; Sathe S; Anande G; Xu J; Minden M; Yeo G; Unnikrishnan A; Hope K; Lu Y, 2021, 'RBM17 Mediates Evasion of Pro-Leukemic Factors from Splicing-coupled NMD to Enforce Leukemic Stem Cell Maintenance', , http://dx.doi.org/10.21203/rs.3.rs-728533/v1

Saini SK; Ørskov AD; Bjerregaard AM; Unnikrishnan A; Holmberg-Thydén S; Borch A; Jensen KV; Anande G; Bentzen AK; Marquard AM; Tamhane T; Treppendahl MB; Gang AO; Dufva IH; Szallasi Z; Ternette N; Pedersen AG; Eklund AC; Pimanda J; Grønbæk K; Hadrup SR, 2020, 'Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers', Nature Communications, vol. 11, http://dx.doi.org/10.1038/s41467-020-19464-8

Anande G; Deshpande NP; Mareschal S; Batcha AMN; Hampton HR; Herold T; Lehmann S; Wilkins MR; Wong JWH; Unnikrishnan A; Pimanda JE, 2020, 'RNA Splicing Alterations Induce a Cellular Stress Response Associated with Poor Prognosis in Acute Myeloid Leukemia', Clinical Cancer Research, vol. 26, pp. 3597 - 3607, http://dx.doi.org/10.1158/1078-0432.CCR-20-0184

Khanna A; Thoms JAI; Stringer BW; Chung SA; Ensbey KS; Jue TR; Jahan Z; Subramanian S; Anande G; Shen H; Unnikrishnan A; McDonald KL; Day BW; Pimanda JE, 2020, 'Constitutive CHK1 Expression Drives a pSTAT3-CIP2A Circuit that Promotes Glioblastoma Cell Survival and Growth', Molecular cancer research : MCR, vol. 18, pp. 709 - 722, http://dx.doi.org/10.1158/1541-7786.MCR-19-0934

Anande G; Deshpande N; Mareschal S; Batcha A; Hampton H; Herold T; Lehmann S; Wilkins M; Wong JWH; Unnikrishnan A; Pimanda J, 2020, 'RNA splicing alterations induce a cellular stress response associated with poor prognosis in AML', , http://dx.doi.org/10.1101/2020.01.10.895714

Kumar P; Beck D; Galeev R; Thoms JAI; Talkhoncheh MS; de Jong I; Unnikrishnan A; Baudet A; Subramaniam A; Pimanda JE; Larsson J, 2019, 'HMGA2 promotes long-term engraftment and myeloerythroid differentiation of human hematopoietic stem and progenitor cells', Blood Advances, vol. 3, pp. 681 - 691, http://dx.doi.org/10.1182/bloodadvances.2018023986

Smeets MF; Tan SY; Xu JJ; Anande G; Unnikrishnan A; Chalk AM; Taylor SR; Pimanda JE; Wall M; Purton LE; Walkley CR, 2018, 'Srsf2P95H initiates myeloid bias and myelodysplastic/ myeloproliferative syndrome from hemopoietic stem cells', Blood, vol. 132, pp. 608 - 621, http://dx.doi.org/10.1182/blood-2018-04-845602

Ali A; Penneroux J; Dal Bello R; Massé A; Quentin S; Unnikrishnan A; Hernandez L; Raffoux E; Ben Abdelali R; Renneville A; Preudhomme C; Pimanda J; Dombret H; Soulier J; Fenaux P; Clappier E; Adès L; Puissant A; Itzykson R, 2018, 'Granulomonocytic progenitors are key target cells of azacytidine in higher risk myelodysplastic syndromes and acute myeloid leukemia', Leukemia, vol. 32, pp. 1856 - 1860, http://dx.doi.org/10.1038/s41375-018-0076-2

Unnikrishnan A; Vo ANQ; Pickford R; Raftery MJ; Nunez AC; Verma A; Hesson LB; Pimanda JE, 2018, 'AZA-MS: A novel multiparameter mass spectrometry method to determine the intracellular dynamics of azacitidine therapy in vivo', Leukemia, vol. 32, pp. 900 - 910, http://dx.doi.org/10.1038/leu.2017.340

Unnikrishnan A; Papaemmanuil E; Beck D; Deshpande NP; Verma A; Kumari A; Woll PS; Richards LA; Knezevic K; Chandrakanthan V; Thoms JAI; Tursky ML; Huang Y; Ali Z; Olivier J; Galbraith S; Kulasekararaj AG; Tobiasson M; Karimi M; Pellagatti A; Wilson SR; Lindeman R; Young B; Ramakrishna R; Arthur C; Stark R; Crispin P; Curnow J; Warburton P; Roncolato F; Boultwood J; Lynch K; Jacobsen SEW; Mufti GJ; Hellstrom-Lindberg E; Wilkins MR; MacKenzie KL; Wong JWH; Campbell PJ; Pimanda JE, 2017, 'Integrative Genomics Identifies the Molecular Basis of Resistance to Azacitidine Therapy in Myelodysplastic Syndromes', Cell Reports, vol. 20, pp. 572 - 585, http://dx.doi.org/10.1016/j.celrep.2017.06.067

Poulos RC; Thoms JAI; Guan YF; Unnikrishnan A; Pimanda JE; Wong JWH, 2016, 'Functional Mutations Form at CTCF-Cohesin Binding Sites in Melanoma Due to Uneven Nucleotide Excision Repair across the Motif', Cell Reports, vol. 17, pp. 2865 - 2872, http://dx.doi.org/10.1016/j.celrep.2016.11.055

Unnikrishnan A; Guan YF; Huang Y; Beck D; Thoms JAI; Peirs S; Knezevic K; Ma S; De Walle IV; De Jong IDE; Ali Z; Zhong L; Raftery MJ; Taghon T; Larsson J; MacKenzie KL; Van Vlierberghe P; Wong JWH; Pimanda JE, 2016, 'A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network', Nucleic Acids Research, vol. 44, pp. 10644 - 10661, http://dx.doi.org/10.1093/nar/gkw804

Nasrallah R; Fast EM; Solaimani P; Knezevic K; Eliades A; Patel R; Thambyrajah R; Unnikrishnan A; Thoms J; Beck D; Vink CS; Smith A; Wong J; Shepherd M; Kent D; Roychoudhuri R; Paul F; Klippert J; Hammes A; Willnow T; Göttgens B; Dzierzak E; Zon LI; Lacaud G; Kouskoff V; Pimanda JE, 2016, 'Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes', Blood, vol. 128, pp. 1928 - 1939, http://dx.doi.org/10.1182/blood-2016-02-697870

Botezatu L; Michel LC; Makishima H; Schroeder T; Germing U; Haas R; Van der Reijden B; Marneth AE; Bergevoet SM; Jansen JH; Przychodzen B; Wlodarski M; Niemeyer C; Platzbecker U; Ehninger G; Unnikrishnan A; Beck D; Pimanda J; Hellström-Lindberg E; Malcovati L; Boultwood J; Pellagatti A; Papaemmanuil E; Le Coutre P; Kaeda J; Opalka B; Möröy T; Dührsen U; Maciejewski J; Khandanpour C, 2016, 'GFI136N as a therapeutic and prognostic marker for myelodysplastic syndrome', Experimental Hematology, vol. 44, pp. 590 - 595.e1, http://dx.doi.org/10.1016/j.exphem.2016.04.001

Chandrakanthan V; Yeola A; Kwan JC; Oliver RA; Qiao Q; Kang YC; Zarzour P; Beck D; Boelen L; Unnikrishnan A; Villanueva JE; Nunez AC; Knezevic K; Palu C; Nasrallah R; Carnell M; Macmillan A; Whan R; Yu Y; Hardy P; Grey ST; Gladbach A; Delerue F; Ittner L; Mobbs R; Walkley CR; Purton LE; Ward RL; Wong JWH; Hesson LB; Walsh W; Pimanda JE, 2016, 'Pdgf-ab and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells', Proceedings of the National Academy of Sciences of the United States of America, vol. 113, pp. E2306 - E2315, http://dx.doi.org/10.1073/pnas.1518244113

Tursky ML; Beck D; Thoms JAI; Huang Y; Kumari A; Unnikrishnan A; Knezevic K; Evans K; Richards LA; Lee E; Morris J; Goldberg L; Izraeli S; Wong JWH; Olivier J; Lock RB; MacKenzie KL; Pimanda JE, 2015, 'Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias', Leukemia, vol. 29, pp. 819 - 827, http://dx.doi.org/10.1038/leu.2014.299

Woll PS; Kjällquist U; Chowdhury O; Doolittle H; Wedge DC; Thongjuea S; Erlandsson R; Ngara M; Anderson K; Deng Q; Mead AJ; Stenson L; Giustacchini A; Duarte S; Giannoulatou E; Taylor S; Karimi M; Scharenberg C; Mortera-Blanco T; Macaulay IC; Clark SA; Dybedal I; Josefsen D; Fenaux P; Hokland P; Holm MS; Cazzola M; Malcovati L; Tauro S; Bowen D; Boultwood J; Pellagatti A; Pimanda JE; Unnikrishnan A; Vyas P; Göhring G; Schlegelberger B; Tobiasson M; Kvalheim G; Constantinescu SN; Nerlov C; Nilsson L; Campbell PJ; Sandberg R; Papaemmanuil E; Hellström-Lindberg E; Linnarsson S; Jacobsen SEW, 2015, 'Erratum to Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo, [Cancer Cell, 25, 2014, 794-808]', Cancer Cell, vol. 27, pp. 603 - 605, http://dx.doi.org/10.1016/j.ccell.2015.03.003

Woll PS; Kjaellquist U; Chowdhury O; Doolittle H; Wedge DC; Thongjuea S; Erlandsson R; Ngara M; Anderson K; Deng Q; Mead AJ; Stenson L; Giustacchini A; Duarte S; Giannoulatou E; Taylor S; Karimi M; Scharenberg C; Mortera-Blanco T; Macaulay IC; Clark S-A; Dybedal I; Josefsen D; Fenaux P; Hokland P; Holm MS; Cazzola M; Malcovati L; Tauro S; Bowen D; Boultwood J; Pellagatti A; Pimanda JE; Unnikrishnan A; Vyas P; Goehring G; Schlegelberger B; Tobiasson M; Kvalheim G; Constantinescu SN; Nerlov C; Nilsson L; Campbell PJ; Sandberg R; Papaemmanuil E; Hellstroem-Lindberg E; Linnarsson S; Jacobsen SEW, 2015, 'Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo (vol 25, pg 794, 2014)', CANCER CELL, vol. 27, pp. 603 - 605, http://dx.doi.org/10.1016/j.ccell.2015.03.003

Lacramioara B; Makishima H; Michel L; Hoenes J; Marneth A; van der Reijden B; Radiovoyevich T; Germing U; Haas R; Schroeder T; Vadnais C; Helness A; Pimanda J; Jansen J; Unnikrishnan A; Platzbecker U; Papaemmanuil E; Ehninger G; Moroy T; Duhrsen U; Maciejewski J; Khandanpour C, 2015, '72 PERSONALIZED TREATMENT APPROACH FOR GFI136N HETEROZYGOUS OR HOMOZYGOUS MDS PATIENTS', Leukemia Research, vol. 39, pp. S35 - S35, http://dx.doi.org/10.1016/s0145-2126(15)30073-4

Tobiasson M; Karimi M; Dimitriou M; Qu Y; Lennartsson A; Ali HA; Unnikrishnan A; Jadersten M; Jansson M; Ben Azenkoud A; Pimanda JE; Ekwall K; Ungerstedt J; Lehmann S; Hellstrom-Lindberg E, 2014, 'Mutations in Histone Modulators and HOXA5 Methylation Levels Affects Survival in Azacitidine Treated MDS Patients', BLOOD, vol. 124, http://www.bloodjournal.org/content/124/21/4613

Woll PS; Kjaellquist U; Chowdhury O; Doolittle H; Wedge DC; Thongjuea S; Erlandsson R; Ngara M; Anderson K; Deng Q; Mead AJ; Stenson L; Giustacchini A; Duarte S; Giannoulatou E; Taylor S; Karimi M; Scharenberg C; Mortera-Blanco T; Macaulay IC; Clark S-A; Dybedal I; Josefsen D; Fenaux P; Hokland P; Holm MS; Cazzola M; Malcovati L; Tauro S; Bowen D; Boultwood J; Pellagatti A; Pimanda JE; Unnikrishnan A; Vyas P; Goehring G; Schlegelberger B; Tobiasson M; Kvalheim G; Constantinescu SN; Nerlov C; Nilsson L; Campbell PJ; Sandberg R; Papaemmanuil E; Hellstroem-Lindberg E; Linnarsson S; Jacobsen SEW, 2014, 'Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo (vol 25, pg 794, 2014)', CANCER CELL, vol. 25, pp. 861 - 861, http://dx.doi.org/10.1016/j.ccr.2014.05.027

Ju YSE; Alexandrov LB; Gerstung M; Martincorena I; Nik-Zainal S; Ramakrishna M; Davies HR; Papaemmanuil E; Gundem G; Shlien A; Bolli N; Behjati S; Tarpey PS; Nangalia J; Massie CE; Butler AP; Teague JW; Vassiliou GS; Green AR; Du MQ; Unnikrishnan A; Pimanda JE; Teh BTE; Munshi N; Greaves M; Vyas P; El-Naggar AK; Santarius T; Collins VP; Grundy R; Taylor JA; Hayes DN; Malkin D; Foster CS; Warren AY; Whitaker HC; Brewer D; Eeles R; Cooper C; Neal D; Visakorpi T; Isaacs WB; Bova GS; Flanagan AM; Futreal PA; Lynch AG; Chinnery PF; McDermott U; Stratton MR; Campbell PJ, 2014, 'Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer', eLife, vol. 3, http://dx.doi.org/10.7554/eLife.02935

Beck D; Thoms JAI; Perera D; Schütte J; Unnikrishnan A; Knezevic K; Kinston SJ; Wilson NK; O'Brien TA; Göttgens B; Wong JWH; Pimanda JE, 2013, 'Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes', Blood, vol. 122, pp. e12 - e22, http://dx.doi.org/10.1182/blood-2013-03-490425

Unnikrishnan A; Akiyoshi B; Biggins S; Tsukiyama T, 2012, 'An efficient purification system for native minichromosome from Saccharomyces cerevisiae', Methods in Molecular Biology, vol. 833, pp. 115 - 123, http://dx.doi.org/10.1007/978-1-61779-477-3_8

Beck D; Brandl MB; boelen L; Unnikrishnan A; Pimanda JE; Wong JWH, 2012, 'Signal analysis for genome-wide maps of histone modifications measured by ChIP-seq', Bioinformatics, vol. 28, pp. 1062 - 1069, http://dx.doi.org/10.1093/bioinformatics/bts085

Unnikrishnan A; Gafken PR; Tsukiyama T, 2010, 'Dynamic changes in histone acetylation regulate origins of DNA replication', Nature Structural & Molecular Biology, vol. 17, pp. 430 - 437, http://dx.doi.org/10.1038/nsmb.1780


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