Researcher

Dr Audrey Indrawati Sutanto-Adji

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Biography

I completed my PhD in Biomedical Engineering from Macquarie University, Sydney, in 2016. My research focus is to characterise change in cardiac ejection pattern, cardiac contractility and arterial pulsatile function of human circulation due to aging and cardiovascular diseases. This is achieved using a hemodynamic approach, through application of both medicine and engineering principles to cardiovascular physiology. I have been working on this...view more

I completed my PhD in Biomedical Engineering from Macquarie University, Sydney, in 2016. My research focus is to characterise change in cardiac ejection pattern, cardiac contractility and arterial pulsatile function of human circulation due to aging and cardiovascular diseases. This is achieved using a hemodynamic approach, through application of both medicine and engineering principles to cardiovascular physiology. I have been working on this area since completing my Master of Biomedical Engineering degree from the University of New South Wales, Sydney, in 2001. I have extended my research interest further into potential deleterious effect of aging pulsatile circulatory function on the cerebral circulation through collaborative work worldwide. To date, I have published papers in various scientific journals, and presented my work in numerous international and ntional scientific meetings. I have won a number of scientific awards and prizes, including the inaugural 2018 International Society of Hypertension Mid-Career Award for Women Researchers.

I joined the Cardiac Mechanics Laboratory at the Victor Chang Cardiac Research Institute in 2019 led by Professor Christopher Hayward. My objective is to investigate the clinical impications of the arterial (non-)pulsatility in individuals with continuous flow heart assist device, or "reduced pulsatility" mechanical circulatory systems. 


My Grants

I was Associate Investigator on a successful St Vincent’s Clinic Foundation Research Grant 2018 (CI: Associate Professor David Muller) on “Quantification of heart and circulatory function in patients with heart valve obstruction”. I started in my current research position in the Mechanical Circulatory Support Laboratory in 2019, and have established protocols to allow progression of grant applications.


My Qualifications

PhD in Biomedical Engineering, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, Australia (2007 - 2016 P/T); research project "Non-Invasive Characterisation of Age-Related Changes in Ascending Aortic Blood Pressure and Blood Flow: From Old Concept to Novel Approach"

Graduate Certificate in Statistics, University of Newcastle, Newcastle, Australia (2004 - 2006)

Master of Biomedical Engineering, Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia (1999 - 2001)

Bachelor of Medicine, Faculty of Medicine, Universitas Atmajaya, Jakarta, Indonesia (1992 - 1997)


My Awards

High Blood Pressure Research Council of Australia Early Career Researcher Moderated Poster Award 2019 (first author and presenter): Non-invasive estimation of ascending aortic impedance to assess ventricular load in aortic stenosis patients using cardiac MR and applanation tonometry.

International Society of Hypertension Young Investigators Moderated Poster Award 2019 (first author and presenter): A disparate phenomenon of pulse wave reflection with sex in obese individuals.

International Society of Hypertension Mid-Career Award for Women Researchers 2018 (the first recipient): Outstanding work and impressive publication record in the field of hypertension whilst being a role model.

High Blood Pressure Foundation of Australia Travel Award 2018 (presenter): Financial support for selected young investigators to attend and present at the International Society Hypertension Scientific Meeting, Beijing, China.


My Research Activities

  • Cardiovascular hemodynamics and cardiac contractility
  • Arterial pulsatility in humans and its characteristic change with aging and disease
  • Association of arterial stiffness and pulse wave reflection (arterial pressure and flow), its deviation from normal function and deleterious effect to the brain
  • Arterial (non-)pulsatility in individuals with continuous pump heart assist device (mechanical circulatory system)

My Research Supervision


Areas of supervision

Cardiovascular hemodynamics and arterial pulsatility

Non-estimation of cardiac load from arterial pressure and flow recordings

(Non-)pulsatility in mechanical heart assist with continuous pump

Arterial pressure and flow waveform morphology and its related indices

Non-invasive arterial pressure and flow monitoring

 


Currently supervising

Master of Research student (from Rural Clinical School, UNSW) with expected completion end of 2020 (co-supervisor)

Potentially 2 BSc (Med) Hons projects commencing 2021 (co-supervisor)

 


My Engagement

I regularly review articles for journals including the American Journal of Hypertension, Journal of Human Hypertension and Scientific Reports. I have been invited and have accepted the American Journal of Hypertension offer to serve on the Editorial Board from 2020-2022. I have reviewed abstracts submitted for the Asia Pacific Congress in Hypertension meeting held in Brisbane, 24-27 November 2019. In the same meeting, I also acted as a session chair and a judge for the student poster award, as well as the co-organiser for the Satellite Symposium on Central Blood Pressure.

I am a member of the High Blood Pressure Research Council of Australia (HBPRCA), Franklin Women (a women’s organisation working in health and medical research), the Heart Foundation NSW Cardiovascular Research Network, and the International Society of Hypertension (international peak body supporting research into high blood pressure related diseases).vI served on the HBPRCA Early Career Researchers Committee in 2019 (as Secretary) and am currently serving on the HBPRCA Executive Committee from 2020-2022 with a specific role of “Women in Hypertension” (research).

 

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