By Dr Bill Giannakopoulos

Journal articles

Giannakopoulos B; Krilis SA, 2024, 'Domain 5 of Beta 2 glycoprotein I: Friend or foe in health? Context matters', Clinical Immunology, 265, http://dx.doi.org/10.1016/j.clim.2024.110282

Barbhaiya M; Zuily S; Amigo MC; Andrade D; Avcin T; Bertolaccini ML; Branch DW; Costedoat-Chalumeau N; Crowther M; Ramires de Jesus G; Devreese KMJ; Frances C; Garcia D; Gómez-Puerta JA; Guillemin F; Levine SR; Levy RA; Lockshin MD; Ortel TL; Petri M; Sanna G; Sciascia S; Seshan SV; Tektonidou MG; Wahl D; Willis R; Yelnik C; Hendry A; Naden R; Costenbader K; Erkan D; Agmon-Levin N; Aguilar C; Alba P; Alpan O; Ambrozic A; Andrade L; Appenzeller S; Berkun Y; Cabral A; Canaud G; Chen P; Chighizola C; Cimaz R; Cuadrado MJ; de Groot PG; de Moerloose P; Derksen R; Dörner T; Fortin P; Giannakopoulos B; Gonzalez EB; Inanc M; Kenet G; Khamashta M; Kriegel M; Krilis S; Ladha D; Manneville F; Massicotte P; McCarty G; Mikdashi J; Myones B; Sammaritano L; Signorelli F; Soybilgic A; Woller S; Zuo R, 2024, 'Development of the 2023 ACR/EULAR Antiphospholipid Syndrome Classification Criteria, Phase III-D Report: Multicriteria Decision Analysis', Arthritis Care and Research, http://dx.doi.org/10.1002/acr.25415

Zuo Y; Navaz S; Tsodikov A; Kmetova K; Kluge L; Ambati A; Hoy CK; Yalavarthi S; de Andrade D; Tektonidou MG; Sciascia S; Pengo V; Ruiz-Irastorza G; Belmont HM; Gerosa M; Fortin PR; de Jesus GR; Branch DW; Andreoli L; Rodriguez-Almaraz E; Petri M; Cervera R; Willis R; Karp DR; Li QZ; Cohen H; Bertolaccini ML; Erkan D; Knight JS; Pons-Estel G; Giannakopoulos B; Krilis S; Levy R; Signorelli F; Andrade D; Balbi G; Clarke AE; Skeith L; Ji L; Zhang Z; Yang C; Shi H; Zuily S; Wahl D; Nalli C; Tincani A; Chighizola CB; Meroni P; Cheng C; Pazzola G; Foddai S; Radin M; Davis S; Amengual O; Atsumi T; Uthman I; Limper M; de Groot P; Ugarte A; Rodriguez-Pinto I; Ríos-Garcés R; Barilaro G; Pardos-Gea J; Almaraz ER; Cuadrado MJ; Zamorano MAA; Lopez-Pedrera C; Artim-Esen B; Inanc M; Efthymiou M; Khamashta M; Mackie I; Sanna G; Knight J; Zuo Y; Petri M; Leaf RK; Roubey R; Ortel T; Gonzalez E; Kello N; Belmont M; Levine S; Rand J; Barbhaiya M; Salmon J; Lockshin M; Duarte Garcia AA, 2023, 'Anti–Neutrophil Extracellular Trap Antibodies in Antiphospholipid Antibody–Positive Patients: Results From the Antiphospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking Clinical Database and Repository', Arthritis and Rheumatology, 75, pp. 1407 - 1414, http://dx.doi.org/10.1002/art.42489

Gkrouzman E; Willis R; Andrade D; Tektonidou MG; Pengo V; Ruiz-Irastorza G; Belmont HM; Fortin PR; Gerosa M; Signorelli F; Atsumi T; Branch DW; Nalli C; Rodriguez-Almaraz E; Petri MA; Cervera R; Knight JS; Efthymiou M; Cohen H; Bertolaccini ML; Erkan D; Roubey R; Pons-Estel G; Giannakopoulos B; Krilis S; de Jesus G; Levy R; Balbi G; Clarke AE; Skeith L; Ji L; Zhang Z; Yang C; Shi H; Zuily S; Wahl D; Andreoli L; Tincani A; Chighizola CB; Meroni P; Cheng C; Pazzola G; Sciascia S; Foddai S; Radin M; Davis S; Amengual O; Uthman I; Limper M; Groot PD; Ruiz—Irastorza G; Ugarte A; Rodriguez-Pinto I; Pardos-Gea J; Cuadrado MJ; Aguirre Zamorano MA; Lopez-Pedrera C; Artim-Esen B; Inanc M; Khamashta M; Mackie I; Sanna G; Knight J; Zuo Y; Petri M; Leaf RK; Ortel T; Gonzalez E; Kello N; Belmont M; Levine S; Rand J; Barbhaiya M; Salmon J; Lockshin M; Duarte Garcia AA, 2023, 'Associations Among Antiphospholipid Antibody Types, Isotypes, and Titers: An AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) Study', Laboratory Investigation, 103, http://dx.doi.org/10.1016/j.labinv.2023.100147

Chighizola CB; Pregnolato F; Andrade D; Tektonidou M; Pengo V; Ruiz-Irastorza G; Belmont HM; Gerosa M; Fortin P; Branch DW; Andreoli L; Petri MA; Cervera R; Knight JS; Willis R; Efthymiou M; Cohen H; Erkan D; Bertolaccini ML; Pons-Estel G; Giannakopoulos B; Krilis S; de Jesus G; Levy R; Signorelli F; Balbi G; Clarke AE; Skeith L; Ji L; Zhang Z; Yang C; Shi H; Zuily S; Wahl D; Nalli C; Tincani A; Meroni PL; Cheng C; Pazzola G; Sciascia S; Foddai S; Radin M; Davis S; Amengual O; Atsumi T; Uthman I; Limper M; de Groot P; Ugarte A; Rodriguez-Pinto I; Barilaro G; Ríos-Garcés R; Pardos-Gea J; Almaraz ER; Cuadrado MJ; Zamorano MAA; Lopez-Pedrera C; Artim-Esen B; Inanc M; Khamashta M; Mackie I; Sanna G; Knight J; Zuo Y; Petri M; Leaf RK; Roubey R; Ortel T; Gonzalez E; Kello N; Belmont M; Levine S; Rand J; Barbhaiya M; Salmon J; Lockshin M; Duarte Garcia AA, 2023, 'Fluctuation of Anti–Domain 1 and Anti–β2-Glycoprotein I Antibody Titers Over Time in Patients With Persistently Positive Antiphospholipid Antibodies', Arthritis and Rheumatology, 75, pp. 984 - 995, http://dx.doi.org/10.1002/art.42459

Passam FH; Chen G; Chen VM; Qi M; Krilis SA; Giannakopoulos B, 2022, 'Βeta-2-glycoprotein I exerts antithrombotic function through its domain V in mice', Journal of Autoimmunity, 126, http://dx.doi.org/10.1016/j.jaut.2021.102747

Barbhaiya M; Zuily S; Ahmadzadeh Y; Amigo MC; Avcin T; Bertolaccini M; Branch DW; de Jesus G; Devreese KMJ; Frances C; Garcia D; Guillemin F; Levine SR; Levy RA; Lockshin MD; Ortel T; Seshan SV; Tektonidou M; Wahl D; Willis R; Naden R; Costenbader K; Erkan D; Agmon-Levin N; Aguilar C; Alba P; Alpan O; Ambrozic A; Amoura Z; Andrade D; Andrade L; Appenzeller S; Esen BA; Atsumi T; Berkun Y; Cabral A; Canaud G; Cervera R; Chen P; Chighizola C; Cimaz R; Cohen H; Costedoat-Chalumeau N; Crowther M; Cuadrado MJ; de Groot PG; de Moerloose P; Derksen R; Diz-Kucukkaya R; Dörner T; Fortin P; Giannakopoulos B; Gómez-Puerta JA; Gonzalez EB; Inanc M; Kenet G; Khamashta M; Kriegel M; Krilis S; Laskin C; Massicotte P; McCarty G; Meroni PL; Mikdashi J; Myones B; Pengo V; Petri M; Roubey R; Sammaritano L; Sanna G; Sciascia S; Signorelli F; Soybilgic A; Tincani A; Woller S; Yelnik C, 2021, 'Development of a New International Antiphospholipid Syndrome Classification Criteria Phase I/II Report: Generation and Reduction of Candidate Criteria', Arthritis Care and Research, 73, pp. 1490 - 1501, http://dx.doi.org/10.1002/acr.24520

Krilis M; Qi M; Ioannou Y; Zhang JY; Ahmadi Z; Wong JWH; Vlachoyiannopoulos PG; Moutsopoulos HM; Koike T; Sturgess AD; Chong BH; Krilis SA; Giannakopoulos B, 2021, 'Clinical relevance of nitrated beta 2-glycoprotein I in antiphospholipid syndrome: Implications for thrombosis risk', Journal of Autoimmunity, 122, http://dx.doi.org/10.1016/j.jaut.2021.102675

Weaver JC; Ullah I; Qi M; Giannakopoulos B; Rye KA; Kockx M; Kritharides L; Krilis SA, 2020, 'Free Thiol β2-GPI (β-2-Glycoprotein-I) Provides a Link Between Inflammation and Oxidative Stress in Atherosclerotic Coronary Artery Disease', Arteriosclerosis, Thrombosis, and Vascular Biology, 40, pp. 2794 - 2804, http://dx.doi.org/10.1161/ATVBAHA.120.315156

Zuily S; Clerc-Urmès I; Bauman C; Andrade D; Sciascia S; Pengo V; Tektonidou MG; Ugarte A; Gerosa M; Michael Belmont H; Zamorano MAA; Fortin P; Ji L; Efthymiou M; Cohen H; Branch DW; Jesus GRD; Nalli C; Petri M; Rodriguez E; Cervera R; Knight JS; Atsumi T; Willis R; Bertolaccini ML; Vega J; Wahl D; Erkan D; Pons-Estel G; Giannakopoulos B; Krilis S; de Jesus G; Levy R; Fortin PF; Zhang Z; Andreoli L; Tincani A; Chighizola CB; Meroni P; Banzato A; Davis S; Amengual O; Uthman I; Limper M; de Groot P; Irastorza GR; Rodríguez-Pintó I; Cuadrado MJ; Lopez-Pedrera R; Artim-Esen B; Inanc M; Khamashta M; Mackie I; Sanna G; Knight J; Roubey R; Ortel T; Gonzalez E; Belmont M; Levine S; Rand J; Barbhaiya M; Salmon J; Lockshin M, 2020, 'Cluster analysis for the identification of clinical phenotypes among antiphospholipid antibody-positive patients from the APS ACTION Registry', Lupus, 29, pp. 1353 - 1363, http://dx.doi.org/10.1177/0961203320940776

Krilis M; Qi M; Qi J; Wong JWH; Guymer R; Liew G; Hunyor AP; Madigan M; McCluskey P; Weaver J; Krilis SA; Giannakopoulos B, 2018, 'Dual roles of different redox forms of complement factor H in protecting against age related macular degeneration', Free Radical Biology and Medicine, 129, pp. 237 - 246, http://dx.doi.org/10.1016/j.freeradbiomed.2018.09.034

Weaver JC; Krilis SA; Giannakopoulos B, 2018, 'Oxidative post-translational modification of βeta 2-glycoprotein I in the pathophysiology of the anti-phospholipid syndrome', Free Radical Biology and Medicine, 125, pp. 98 - 103, http://dx.doi.org/10.1016/j.freeradbiomed.2018.03.048

El-Assaad F; Qi M; Gordon AK; Qi J; Dong S; Passam F; Weaver JC; Giannakopoulos B; Krilis SA, 2017, 'Βeta 2-glycoprotein i protects mice against gram-negative septicaemia in a sexually dimorphic manner', Scientific Reports, 7, pp. 8201, http://dx.doi.org/10.1038/s41598-017-07945-8

Krilis M; Qi M; Madigan MC; Wong JWH; Abdelatti M; Guymer RH; Whitelock J; McCluskey P; Zhang P; Qi J; Hunyor AP; Krilis SA; Giannakopoulos B, 2017, 'Nitration of tyrosines in complement factor H domains alters its immunological activity and mediates a pathogenic role in age related macular degeneration', Oncotarget, 8, pp. 49016 - 49032, http://dx.doi.org/10.18632/oncotarget.14940

Dong S; Qi M; Wang Y; Chen L; Weaver JC; Krilis SA; Giannakopoulos B, 2017, 'β2GPI exerts an anti-obesity effect in female mice by inhibiting lipogenesis and promoting lipolysis', Oncotarget, 8, pp. 92652 - 92666, http://dx.doi.org/10.18632/oncotarget.21536

Ullah I; Qi M; Qi J; Giannakopoulos B; Weaver J; Krilis S, 2017, 'Development of Novel Assays for Quantitation of Total and Free Thiol Beta 2 Glycoprotein I', Heart, Lung and Circulation, 26, pp. S55 - S55, http://dx.doi.org/10.1016/j.hlc.2017.06.027

El-Assaad F; Krilis SA; Giannakopoulos B, 2016, 'Posttranslational forms of beta 2-glycoprotein I in the pathogenesis of the antiphospholipid syndrome', Thrombosis Journal, 14, pp. 20, http://dx.doi.org/10.1186/s12959-016-0115-z

Zhou S; Chen G; Qi M; El-Assaad F; Wang Y; Dong S; Chen L; Yu D; Weaver JC; Beretov J; Krilis SA; Giannakopoulos B, 2016, 'Gram negative bacterial inflammation ameliorated by the plasma protein beta 2-Glycoprotein I', Scientific Reports, 6, pp. 33656, http://dx.doi.org/10.1038/srep33656

Zhou S; Tanaka K; O'Keeffe M; Qi M; El-Assaad F; Weaver JC; Chen G; Weatherall C; Wang Y; Giannakopoulos B; Chen L; Yu DM; Hamilton MJ; Wensing LA; Stevens RL; Krilis SA, 2016, 'CD117⁺ dendritic and mast cells are dependent on RasGRP4 to function as accessory cells for optimal natural killer cell-mediated responses to lipopolysaccharide', PLoS ONE, 11, pp. e0151638, http://dx.doi.org/10.1371/journal.pone.0151638

Zhang P; Weaver JC; Chen G; Beretov J; Atsumi T; Qi M; Bhindi R; Qi JC; Madigan MC; Giannakopoulos B; Krilis SA, 2016, 'The fifth domain of beta 2 glycoprotein I protects from natural IgM mediated cardiac ischaemia reperfusion injury', PLoS ONE, 11, pp. e0152681, http://dx.doi.org/10.1371/journal.pone.0152681

Qi M; Abdelatti M; Krilis M; Madigan MC; Weaver J; Guymer RH; McCluskey P; Wang Y; Zhou S; Krilis SA; Giannakopoulos B, 2016, 'Do Beta 2-Glycoprotein i Disulfide Bonds Protect the Human Retina in the Setting of Age-Related Macular Degeneration?', Antioxidants and Redox Signaling, 24, pp. 32 - 38, http://dx.doi.org/10.1089/ars.2014.6052

Rahgozar S; Amirian T; Qi M; Shahshahan Z; Entezar-E-Ghaem M; Tehrani HG; Miroliaei M; Krilis SA; Giannakopoulos B, 2015, 'Improved assay for quantifying a redox form of angiotensinogen as a biomarker for pre-eclampsia: A case-control study', PLoS ONE, 10, pp. e0135905, http://dx.doi.org/10.1371/journal.pone.0135905

Krilis SA; Giannakopoulos B, 2014, 'Laboratory methods to detect antiphospholipid antibodies', Hematology (United States), 2014, pp. 321 - 328, http://dx.doi.org/10.1182/asheducation-2014.1.321

Giannakopoulos B; Krilis S, 2014, 'In APS, two A1's are better than one!', Blood, 123, pp. 955 - 956, http://dx.doi.org/10.1182/blood-2013-12-542506

Giannakopoulos B; Mirarabshahi P; Qi M; Weatherall C; Qi JC; Tanaka K; Millar E; Vonthethoff L; Gatto D; Spielman D; Krilis SA, 2014, 'Deletion of the antiphospholipid syndrome autoantigen β2- glycoprotein i potentiates the lupus autoimmune phenotype in a toll-like receptor 7-mediated murine model', Arthritis and Rheumatology, 66, pp. 2270 - 2280, http://dx.doi.org/10.1002/art.38646

Krilis M; Mao Q; Madigan M; Wong J; Abulatti M; Guymer R; McCluskey P; Zhang P; Qi J; Krilis S; Giannakopoulos B, 2013, 'POST TRANSLATIONALLY MODIFIED COMPLEMENT FACTOR H IN AGE RELATED MACULAR DEGENERATION', CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 41, pp. 17 - 17, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000329507100022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Giannakopoulos B; Krilis S, 2013, 'The Pathogenesis of the Antiphospholipid Syndrome', New England Journal of Medicine, 368, pp. 1033 - 1044

Giannakopoulos B; Gao L; Qi M; Wong JW; Yu D; Vlachoyiannopoulos P; Moutsopoulos HM; Atsumi T; Koike T; Hogg PJ; Qi JC; Krilis S, 2012, 'Factor XI is a substrate for oxidoreductases: Enhanced activation of reduced FXI and its role in antiphospholipid syndrome thrombosis.', Journal of Autoimmunity, 39, pp. 121 - 129, http://dx.doi.org/10.1016/j.jaut.2012.05.005

Krilis S; Passam F; Giannakopoulos B; Mirarabshahi P, 2011, 'Molecular pathophysiology of the antiphospholipid syndrome: the role of oxidative posttranslational modification of beta 2 glycoprotein I', JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 9, pp. 715 - 715, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208992803015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Giannakopoulos B; Mirarabshahi P; Krilis S, 2011, 'New insights into the biology and pathobiology of beta2-glycoprotein I.', Current Rheumatology Reports, 13, pp. 90 - 95, http://dx.doi.org/10.1007/s11926-010-0151-9

Passam F; Rahgozar S; Qi M; Raftery MJ; Wong JWH; Tanaka K; Ioannou Y; Zhang JY; Gemmell R; Qi JC; Giannakopoulos B; Hughes WE; Hogg PJ; Krilis S; Qi J, 2011, 'Redox control of â2-glycoprotein I-von Willebrand factor interaction by thioredoxin-1.', Journal of Thrombosis and Haemostasis, 8, pp. 1754 - 1762, http://dx.doi.org/10.1111/j.1538-7836.2010.03944.x

Ioannou Y; Zhang JY; Passam FH; Rahgozar S; Qi JC; Giannakopoulos B; Qi M; Yu P; Yu DM; Hogg PJ; Krilis SA, 2010, 'Naturally occurring free thiols within β2-glycoprotein I in vivo: Nitrosylation, redox modification by endothelial cells, and regulation of oxidative stress-induced cell injury', Blood, 116, pp. 1961 - 1970, http://dx.doi.org/10.1182/blood-2009-04-215335

Passam F; Rahgozar S; Qi M; Raftery MJ; Wong J; Tanaka K; Ioannou Y; Zhang JY; Gemmell R; Qi JC; Giannakopoulos B; Hughes WE; Hogg PJ; Krilis S, 2010, 'Beta 2 glycoprotein I is a substrate of thiol oxidoreductases', Blood, 116, pp. 1995 - 1997, http://bloodjournal.hematologylibrary.org/cgi/content/citation/116/11/1995

Giannakopoulos B; Krilis S, 2009, 'How I treat the antiphospholipid syndrome', Blood, 114, pp. 2020 - 2030

Krilis S; Giannakopoulos B; Passam F; Ioannou Y, 2009, 'How we diagnose the antiphospholipid syndrome', Blood, 113, pp. 985 - 994

Reed J; Giannakopoulos B; Jackson M; Krilis S; Gordon T, 2009, 'Ro 60 functions as a receptor for β2-glycoprotein I on apoptotic cells', Arthritis Care & Research, 60, pp. 860 - 869

Krilis S; Reed J; Giannakopoulos B; Jackson M; Gordon T, 2009, 'Ro60 Functions as a receptor for B2-glycoprotein I on apoptotic cells', Arthritis Care & Research, 60, pp. 985 - 994

Rahgozar S; Giannakopoulos B; Yan X; Wei J; Jian CQ; Gemmell R; Krilis SA, 2008, 'Beta2-glycoprotein I protects thrombin from inhibition by heparin cofactor II: Potentiation of this effect in the presence of anti-β2-glycoprotein I autoantibodies', Arthritis and Rheumatism, 58, pp. 1146 - 1155, http://dx.doi.org/10.1002/art.23387

Krilis S; Rahgozar S; Giannakopoulos B; Qi JC; Gemmell R; Yan X; Wei J, 2008, 'Beta2- Glycoprotein I Protects Thrombin from Inhibition by Heparin Cofactor II', Arthritis Care & Research, 58, pp. 1146 - 1155

Rahgozar S; Yang Q; Giannakopoulos B; Yan X; Miyakis S; Krilis SA, 2007, 'Beta2-glycoprotein I binds thrombin via exosite I and exosite II: Anti-β2-glycoprotein I antibodies potentiate the inhibitory effect of β2-glycoprotein I on thrombin-mediated factor XIa generation', Arthritis and Rheumatism, 56, pp. 605 - 613, http://dx.doi.org/10.1002/art.22367

Giannakopoulos B; Shi T; Yan XK; Yu P; Berndt MC; Andrew R; Rivera J; Iverson GM; Cockerill KA; Linnik MD; Krilis S, 2007, 'Anti-beta(2)-glycoprotein I antibodies in complex with beta(2)-glycoprotein I can activate platelets via glycoprotein Ib-IX-V', Clinical and Experimental Rheumatology, 25, pp. 159 - 160

Rahgozar S; Yang Q; Giannakopoulos B; Yan XK; Miyakis S; Krilis S, 2007, 'Beta(2)-glycoprotein I binds thrombin via exosite I and exosite II Anti-beta(2)-glycoprotein I antibodies potentiate the inhibitory effect of beta(2)-glycoprotein I on thrombin-mediated factor XIa generation', Arthritis Care & Research, 56, pp. 605 - 613

Giannakopoulos B; Passam F; Rahgozar S; Krilis S, 2007, 'Current concepts on the pathogenesis of the antiphospholipid syndrome', Blood, 109, pp. 422 - 430

Shi T; Giannakopoulos B; Yan X; Yu P; Berndt MC; Andrews RK; Rivera J; Iverson GM; Cockerill KA; Linnik MD; Krilis SA, 2006, 'Anti-β2-glycoprotein I antibodies in complex with β2-glycoprotein I can activate platelets in a dysregulated manner via glycoprotein Ib-IX-V', Arthritis and Rheumatism, 54, pp. 2558 - 2567, http://dx.doi.org/10.1002/art.21968

Shi T; Giannakopoulos B; Yan XK; Yu P; Berndt MC; Andrews RK; Rivera J; Iverson M; Cockerill KA; Linnik MD; Krilis S, 2006, 'Anti-Beta2-Glycoprotein I Antibodies in Complex With Beta2-Glycoprotein I Can Activate Platelets in a Dysregulated Manner Via Glycoprotein Ib-IX-V', Arthritis Care & Research, 54, pp. 2558 - 2567

Shi T; Giannakopoulos B; Iverson M; Cockerill KA; Linnik MD; Krilis S, 2005, 'Domain V of B2-Glycoprotein I Binds Factor XI/XIa and Is Cleaved of Lys317-Thr318', The Journal of Biological Chemistry, 280, pp. 907 - 912

Yang Q; Shi T; Cheyne B; Giannakopoulos B; Krilis S, 2004, 'Anti-beta(2) glycoprotein I antibodies potentiate the inhibitory effects of beta(2)glycoprotein I on the activation of FXI by FIIa: Effect of clipped beta(2) glycoprotein I', Thrombosis Research, 114, pp. 608 - 608

Miyakis S; Giannakopoulos B; Krilis S, 2004, 'Beta 2-Glycoprotein I-function in health and disease', Thrombosis Research, 114, pp. 335 - 346

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